• Title/Summary/Keyword: Activity Cost

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Multimeric Expression of the Antimicrobial Peptide Buforin II in Escherichia coli by Fusion to a Cysteine-Rich Acidic Peptide

  • Lee, Jae-Hyun;Kim, Jeong-Hyun;Hong, Seung-Suh;Lee, Hyun-Soo;Kim, Sun-Chang
    • Journal of Microbiology and Biotechnology
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    • v.9 no.3
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    • pp.303-310
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    • 1999
  • A cost-effective mass production method for a strong antimicrobial peptide, buforin II, which was isolated from the stomach of Bufo bufo gargarizans, has been developed. This method is based on the neutralization of the positive charge of buforin II by fusion with a cysteine-rich acidic peptide (CAP) to avoid any lethal effect on the host. The neutralized fusion peptide was multimerized and expressed in Escherichia coli as tandem repeats to increase the production yield. Multimers of the CAP-buforin II fusion peptide were successfully expressed at high levels in E. coli as inclusion bodies. More than 100mg of pure buforin II was obtained per 11 of E. coli culture after cleaving the multimeric polypeptide with CNBr. The buforin II obtained from the recombinant E. coli had antimicrobial activity identical to that of natural buforin II. The proposed expression system can provide a cost-effective mass production method for both antimicrobial peptides and other host-lethal basic proteins.

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A Case Study on Quality Improvement of Employee Foodservice in Hospital, Seoul - Focused on Cost Control by the Quantity of Non-Offered Meal - (서울 지역 종합병원 직원 급식서비스의 질 향상 사례 연구 -잔식량 분석에 의한 원가 관리 중심으로 -)

  • Lee, Seung-Lim
    • The Korean Journal of Food And Nutrition
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    • v.23 no.3
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    • pp.411-418
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    • 2010
  • The objective of this study was to analyze the effects of non-offered meal on waste reduction in foodservice. To this end, the quantity of non-offered meal before and after Quality Improvement(QI) activity was analyzed, and employee satisfaction with foodservice was investigated. Statistical data analyses can be summarized as follows: The daily quantity of non-offered meal decreased significantly after QI(p<0.001)($27.80{\pm}3.14\;kg$ before QI and $7.22{\pm}4.17\;kg$ after QI). Among 7 items related to employee satisfaction, kindness of meal service staffs improved significantly after QI(p<0.05)($4.05{\pm}0.74$ before QI and $4.21{\pm}0.17$ after QI). No significant difference was found in the variety of menus, or cooking/seasoning of food, and there seemed to be greater satisfaction with taste of food after QI.

The family relationships and the policy implications of dual-earner families with school-aged children (학동기 자녀를 둔 맞벌이가족의 가족관계와 정책적 제언)

  • 김양희
    • Journal of the Korean Home Economics Association
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    • v.30 no.3
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    • pp.285-305
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    • 1992
  • The purpose of this study was to describe the current status of dual-earner families in Seoul. The specific aims of this study were to examine the dynamics of marital relationship, parent-child relationship and old mother-daughter/daughter in law relationship in the same family. The sample consised of 265 dual-earner families was selected based on wives' jobs, primarily non-professional. The information was gathered from working couples and their school-aged children. The findings of this study were as follows: 1. Sex role attitude of husbands was more traditional than their wives. Therefore, housework sharing of husbands was very low and wives' perception of inequity was high. Wives' marital satisfaction was affected by the wives' perception of inequity, joint leisure activity, sexual satisfaction, and wives' job satisfaction. Husbands' marital satisfaction was affected by sexual satisfaction, perceived difficulties and problems of the husbands caused by wives' employment, and the degree of their housework participation. 2. The emotional uneasiness of children during mothers' absence was reported. The communication about mothers' job was helpful to gain children's understanding toward mothers' job. Mothers suffered from guilty feeling of neglecting their children in spite of their good performance of mothering role. 3. The employed daughters/daughters in law perceived high rewards and low cost in relationships with their mothers/mothers in law. The perceived quality of daughter-mother relationship was higher with low cost and high rewards than that of daughter in law/mother in law. Finally practical and policy implications were suggested.

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Study for Plans to Reduce Restaurant Food Waste at Source Based on an Example of Reduction Operation -Y-city's Reform Team of Reduction- (레스토랑 음식물 쓰레기 감량 방안에 관한 연구 -Y시티 저감 활동 프로그램을 중심으로-)

  • Na, Young-Sun;Seo, Min-Suk
    • Culinary science and hospitality research
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    • v.11 no.3 s.26
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    • pp.121-137
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    • 2005
  • Today's rapid industrialization and population concentration in cities lead to a vast economic growth, and consequently, people's increased desire of spending demands abundant and diverse food. As a result in Korea, annual food waste is 4.1 million tons (24.6% of household waste) and daily food waste amount to 11,397 tons which is equivalent to 1,400 loads of 8-ton truck. It is best to recycle toed waste as manure, forage, and fuel than reclamation but separate collection of food waste is very difficult by reason of water content. So only a little portion of food waste from large-scaled restaurants and cafeterias that handle food waste relatively well. requirement for recycling food wastes into forage and manure needless to say, reduction activity is best way. Therefore, large-scaled restaurants and cafeterias need to seek plans to minimize food resource waste thus reducing the cost and waste processing cost by implementing appropriate reduction program.

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QR Adoption and Merchandiser's Activity in the Korean Apparel Industry (국내 의류업체의 QR도입과 머천다이저의 활동에 관한 연구)

  • 신상무
    • Journal of the Korean Home Economics Association
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    • v.36 no.11
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    • pp.141-156
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    • 1998
  • The purpose of this study was to investigate current QR technology usages and merchandisers' roles and information activities in the Korean apparel industry. Data were collected by interview and questionnaire with merchandisers in apparel companies, manufacturing apparels for both men and women. Statistical analyses were t-test, ANOVA, frequency with SAS program. The results of the study were as follows: 1. The usage of QR technology was generally low. But POS, bar-coding, logistics and small lot order were highly used compared to other technologies. CAD, automated sewing operation, unit product system, logistics, and small lot order were more used in domestic national brand than in import license brand. POS applications were more used in product planning division than in others. 2. Merchandisers played important roles in making major decisions on cost price, sales price, manufacturing request, delivery data, production quantity, produce mix, budget planning, market timing and delivery channels. Products planning was conducted mostly on a monthly basis. Price was determined mainly according to cost price, while the production quantity depended on the last year's sales. Usually sales were analyzed on a daily basis. 3. Merchandisers got more information on fashion them and color trend from foreign information sources than from domestic, while more information on fabrication from domestic sources. For fashion design information they used the equal amount from domestic and foreign sources. Over all degree of utilization in each field of fashion information was fugured rather high.

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Time Shortening of Structural Framework of High-rise Apartment Housing for the Urgent Project Area: Focused on the Cases of Insufficient Time or Delayed Projects

  • Bang, Jong-Dae;Lee, Do-Heun;Chun, Young-Soo;Park, Ji-Young;Lee, Bum-Sik;Jun, Myoung-Hoon
    • Land and Housing Review
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    • v.2 no.4
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    • pp.355-365
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    • 2011
  • Construction duration is very important as a factor which comprises three axises of construction management with quality and cost in construction project. In general project condition, construction duration is optimized while minimizing construction cost and securing required quality. However, in case of insufficient project time duration or delayed projects, project progress management is different from those of normal projects. These project areas need solutions to complete work within a given completion day. To time shortening the current duration of each typical floor of structural framework in apartment construction is investigated, and a basic time schedule planning for typical floor of structural framework in normal projects is planned. This study proposed 3 ways for time shortening of urgent project or insufficient construction duration project. Also, This study proposed detailed time shortening method and technical solution conditions while time is shortened.

Design of User Concentration Classification Model by EEG Analysis Based on Visual SCPT

  • Park, Jin Hyeok;Kang, Seok Hwan;Lee, Byung Mun;Kang, Un Gu;Lee, Young Ho
    • Journal of the Korea Society of Computer and Information
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    • v.23 no.11
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    • pp.129-135
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    • 2018
  • In this study, we designed a model that can measure the level of user's concentration by measuring and analyzing EEG data of the subjects who are performing Continuous Performance Test based on visual stimulus. This study focused on alpha and beta waves, which are closely related to concentration in various brain waves. There are a lot of research and services to enhance not only concentration but also brain activity. However, there are formidable barriers to ordinary people for using routinely because of high cost and complex procedures. Therefore, this study designed the model using the portable EEG measurement device with reasonable cost and Visual Continuous Performance Test which we developed as a simplified version of the existing CPT. This study aims to measure the concentration level of the subject objectively through simple and affordable way, EEG analysis. Concentration is also closely related to various brain diseases such as dementia, depression, and ADHD. Therefore, we believe that our proposed model can be useful not only for improving concentration but also brain disease prediction and monitoring research. In addition, the combination of this model and the Brain Computer Interface technology can create greater synergy in various fields.

An Analysis of The Relative Importance for Target Selecting Criteria in Agricultural Environment Conservation Program (농업환경보전 프로그램 사업대상지 선정기준의 상대적 중요도 분석)

  • Kim, Hyeon-Woong;Sung, Jae-Hoon
    • Korean Journal of Organic Agriculture
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    • v.30 no.4
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    • pp.485-497
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    • 2022
  • Agricultural environmental policies to reduce negative externalities and expand positive externalities became common around the world. However, literature regarding the efficient and effective implementation of agricultural environmental policies, such as optional direct payment, is limited. This study, thus, analyzes the relative importance for target selecting-criteria in order to enhance the cost-effectiveness of the Agricultural Environment Conservation Program in Korea. In this context, we conducted survey to 15 experts who are related in agricultural environment policies and analyzed survey results based on ANP method which can consider correlation between selecting criteria. The results show that, in the case field, "soil", "water", and "ecology" field have relative high importance than the other fields. Also, the relative importance for 'improving rural landscape', 'giving nutrient input moderately', and 'conserving agricultural heritage' activities is higher than the other activities. Furthermore, the relative importance among fields and activities of ANP is different from those of AHP. This result implies that it is necessary to consider the correlation between selecting criteria in order to design effectively. Finally, we suggest that in order to enhance the effectiveness of the program, it would be appropriate to assign differential points according to the importance of each activity when identifying appropriate farms.

Localization of hotspots via a lightweight system combining Compton imaging with a 3D lidar camera

  • Mattias Simons;David De Schepper;Eric Demeester;Wouter Schroeyers
    • Nuclear Engineering and Technology
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    • v.56 no.8
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    • pp.3188-3198
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    • 2024
  • Efficient and secure decommissioning of nuclear facilities demands advanced technologies. In this context, gamma-ray detection and imaging are crucial in identifying radioactive hotspots and monitoring radiation levels. Our study is dedicated to developing a gamma-ray detection system tailored for integration into robotic platforms for nuclear decommissioning, offering a safe and automated solution for this intricate task and ensuring the safety of human operators by mitigating radiation exposure and streamlining hotspot localization. Our approach integrates a Compton camera based 3D reconstruction algorithm with a single Timepix3 detector. This eliminates the need for a second detector and significantly reduces system weight and cost. Additionally, combining a 3D camera with the setup enhances hotspot visualization and interpretation, rendering it an ideal solution for practical nuclear decommissioning applications. In a proof-of-concept measurement utilizing a 137Cs source, our system accurately localized and visualized the source in 3D with an angular error of 1° and estimated the activity with a 3% relative error. This promising result underscores the system's potential for deployment in real-world decommissioning settings. Future endeavors will expand the technology's applications in authentic decommissioning scenarios and optimize its integration with robotic platforms. The outcomes of our study contribute to heightened safety and accuracy for nuclear decommissioning works through the advancement of cost-effective and efficient gamma-ray detection systems.

The development of the critical pathway for hysterectomy patients and its effect (자궁절제술 환자의 표준진료지침(Critical pathway) 개발과 적용효과)

  • Kim, Kyung-Hee;Seo, Young-Seung;Tae, Young-Sook;Lee, Hwa-Ja;Jeon, Sung-Sook
    • Journal of Korean Academy of Nursing Administration
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    • v.6 no.1
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    • pp.123-134
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    • 2000
  • This study intended to analyze the effectiveness to obtain by developing the critical pathway presented as the method to improve the quality-betterment and cost effectiveness the through the continuous and consistent patient management for the hysterectomy patient and applying it to the real practice. This study was designed to develop and effect the critical pathway for hysterectomy patients in the way to be possible the intergrated in patient management. It was adopted the process of seven phase to develop a critical pathway. To analyze the application effect of the developed critical pathway, this author offered health care service applying the critical pathway to the hysterectomy patient from July. 20 to Oct. 19. 1999. The study method had been done by investigating the experimental group and control group through the questionnaire on 40 patients who had been inpatient hysterectomy. Dependent variables were measured by modified from satisfaction, and cost and length of hospital stay. The data anlyzed by frequency, x2-test, t-test. The results of this study was as follows; 1. It was decided that the vertical line of the critical pathway was made up of eight items such as monitoring/assessment, treatment, activity, medication, consult. Lab test, diet, patient teaching and horizontal line was 7days from admission to discharge. 2. After the verifying the validity of the expert group about the critical pathway, the horizontal line was amended from hospitalization to five postoperative days and taking their consensus, some contents of the horizontal line was amended and deleted. 3. There was no significant differences in the experimental group and control group in the satisfaction, and significant differences in the cost, the length of hospital stay.

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