• Title/Summary/Keyword: Activity Coefficient

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Measurement of Flash Point for Binary Mixtures of Methanol, Ethanol, 1-propanol and Toluene (Methanol, Ethanol, 1-propanol 그리고 Toluene 이성분 혼합계에 대한 인화점 측정)

  • Hwang, In Chan;Kim, Seon Woo;In, Se Jin
    • Fire Science and Engineering
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    • v.32 no.1
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    • pp.1-6
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    • 2018
  • The flash point is one of the most important parameters used to characterize the ignition and explosion hazards of liquids. Flash points were measured for several binary systems containing toluene, including {methanol+toluene}, {ethanol+toluene}, and {1-propanol+toluene}. Experiments were performed according to the standard test method using a SETA closed cup flash point tester. The measured flash points were compared with the predicted values calculated using the following $G^E$ models: Wilson, NRTL, and UNIQUAC. The average absolute deviation between the predicted and measured lower flash point was less than 1.69 K.

The Leisure Type, Health Status, Self-esteem, and Social Support of the Elderly Living Alone (일부 지역사회 독거노인의 여가활동유형과 건강상태, 자아존중감, 사회적지지와의 관계 연구)

  • Jang, In-Sun
    • Journal of Korean Public Health Nursing
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    • v.20 no.2
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    • pp.130-140
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    • 2006
  • Purpose: This study aimed to analyze the conditions of the leisure type, health status, self-esteem, and social support of the elderly living alone. Method: The subjects were 189 elderly. The instrument was a structured questionnaire. The data were analyzed by descriptive statistics, ANOVA, and Pearson correlation coefficient. Results: The frequency of the leisure types of the elderly living alone was in the order of culture, rest, social activity and sports. The following factors showed a statistically significant relation: gender, education, religion and marital status with leisure type; age, economic status, job and leisure type with perceived health status; education, economic status and religion with self-esteem; and economic status, marital status and religion with social support. There was a negative correlation between ADL and both perceived health status, and self-esteem, but positive correlations between self-esteem and perceived health status, and between social support and both perceived health status and self-esteem. Conclusion: To maintain the quality of life of the elderly living alone, this study suggests that providing various leisure activities could raise self-esteem, and thereby complement for any deficiencies in family and social support.

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Development of Bioluminescence Immunoassay Using Photoprotein, Aequorin and Site-directed Immobilization

  • Shim, Yu-Nee;Rhee, In-sook
    • Bulletin of the Korean Chemical Society
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    • v.24 no.1
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    • pp.70-74
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    • 2003
  • The heterogeneous bioluminescence immunoassay for digoxin was developed using photoprotein, native aequorin as a label and the site-directed immobilization technique based on avidin/biotin interaction. Aequorin is a bioluminescence protein, originally isolated from the jellyfish Aequoria Victoria and an attractive label in analytical applications because of sensitive detection due to virtually no background bioluminescent signal. Digoxin is a cardioactive drug, and its therapeutic level in serum is at low concentration with very narrow therapeutic index. The aequorin-digoxigenin conjugates were synthesized by the N-hydroxysuccinimide ester method and characterized in terms of bioluminescent residual activity. The resulting dose-response curve shows that the detection limit is $1.0\;{\times}\;10^{-10}\;M$ and a dynamic range is three orders of magnitude, which was obtained by $1.0\;{times}\;10^{-10}\;M$ conjugate and 0.9 μg/mL anti-digoxin antibody. Three structurally similar molecules to digoxin were examined for their cross-reactivity. None of these three compounds showed any crossreactivity with digoxin antibody employed in this study. Standard amounts of digoxin corresponding to the therapeutic range were spiked into the each serum solution. Study of the serum matrix effect indicated that correlation coefficient shows good agreement between luminescence light intensity between in buffer and in serum.

Affecting Factors of the Awareness of Biomedical Ethics in Nursing Students (간호학생의 생명의료윤리의식 영향 요인)

  • Chong, Yu Ri;Lee, Young Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.23 no.4
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    • pp.389-397
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    • 2017
  • Purpose: This study was conducted to examine awareness of biomedical ethics, and to identify affecting factors of the awareness of biomedical ethics in nursing students. Methods: The subjects consisted of 266 nursing students their third and fourth years of study. The data were collected from October to December, 2015 by self-report using questionnaires. Data analysis was performed using SPSS/WIN 18.0, descriptive statistics, t-test, ANOVA, $Scheff{\acute{e}}$ test, Pearson correlation coefficient, and multiple regression analysis. Results: The mean score of the awareness of biomedical ethics was $2.81{\pm}0.22$, perception of death was $3.15{\pm}0.36$, and knowledge of brain death, organ donation, and organ transplant was $12.12{\pm}3.02$. The prediction factors of awareness of biomedical ethics were gender (${\beta}=.29$, p<.001), participation in religious activity (${\beta}=.23$, p=.015), and perception of death (${\beta}=.20$, p=.016). The explanation power was 17.1%. Conclusion: These results showed that education about biomedical ethics is necessary for nursing students, and the development of biomedical ethics educational programs should reflect affecting factors.

Comparative Molecular Similarity Index Analysis on 2-(indol-5-yl)thiazolederivatives as Xanthine Oxidase(XO)inhibitors

  • Nagarajan, Santhosh Kumar;Madhavan, Thirumurthy
    • Journal of Integrative Natural Science
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    • v.9 no.3
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    • pp.190-198
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    • 2016
  • Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organsincluding the liver, gut, lung, kidney, heart, brain and plasma. It is involved in gout pathogenesis. In this study, we have performed Comparative Molecular Field Analysis (CoMSIA) on a series of 2-(indol-5-yl) thiazole derivatives as xanthine oxidase (XO) inhibitors to identify the structural variations with their inhibitory activities. Ligand based CoMSIA models were generated based on atom-by-atom matching alignment. In atom-by-atom matching, the bioactive conformation of highly active molecule 11 was generated using systematic search. Compounds were aligned using the bioactive conformation and it is used for model generation. Different CoMSIA models were generated using different alignments and the best model yielded across-validated $q^2$ of 0.698 with five components and non-cross-validated correlation coefficient ($r^2$) of 0.992 with Fisher value as 236.431, and an estimated standard error of 0.068. The predictive ability of the best CoMSIA models was found to be $r{^2}_{pred}$ 0.653. The study revealed the important structural features required for the biological activity of the inhibitors and could provide useful for the designing of novel and potent drugs for the inhibition of Xanthine oxidase.

A Study on Psychological Care for Hospitalized Patients (입원 환자에 대한 심리 간호 연구)

  • Yu, Sook-Ja;Yang, Soo
    • Journal of Korean Academy of Nursing
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    • v.13 no.3
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    • pp.86-94
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    • 1983
  • The purpose of this study were to find out the perceived importance of psychological care, to investigate the nurses perception on the quantity of psychological care activities, and the correlation between the structual variables. 206 registered nurses from general wards of 3 university hospitals in Seoul were randommly sampled. Data were gathered by check-list on the perceived importance and perceived quantity and were analysed by the frequency, percentile scores, ANOVA and Correlation-coefficient. Results are as follows 1. Majority of subjects(96.6%) responded to the psychological care for hospitalized patients being very, and most important nursing care activity Two-third(66%) revealed to be give more or less satisfactory amount of psychological care-to the hospitalized patients. 2. Heavy work-load(79%), personal factors of(33.0%) nurses and the health team and factors of nurse-patient relationship (20.9%) revealed to be the major causes hindering psychological care. 3. To improve quality and the quantity of psychological care, personal and professional development of nurses and the health team(56.8%), improvement of nurse-patient relationships (49.03) and improvement of nurse patient ratio(45%) were suggested. 4. The perceived quantity of psychological care and the educational status revealed significant correlation(p<.005). The perceived quantity and position in nursing revealed significant correlation (p<.01). 5. No significant correlation was revealed between the perceived importance and the perceived quantity of the psychological care.

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Assessment of the Influence of Physical Impairments on Activities in Persons With Stroke

  • Woo, Young-Keun
    • Physical Therapy Korea
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    • v.18 no.4
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    • pp.11-18
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    • 2011
  • The aim of this study was to analyze the relationship between physical impairments and daily activities on the basis of the outcome measurements in stroke patients. Seventy-six stroke patients participated in this study. Two physical therapists evaluated 3 clinical common measurements, i.e., the Fugl-Meyer Assessment (FMA), the Berg Balance Scale (BBS), and the Functional Independence Measure (FIM). Multiple regression analysis was used, as the dependent variables were the BBS and FIM; the independent variables were post-stroke duration, FMA of Upper Extremity (FMU), and FMA of Lower Extremity (FML). In the regression equation of the BBS, the coefficient of determination ($R^2$) was .383, and the FML was found to be the most important variable for determining the BBS score. In the regression equation of the FIM, $R^2$ was .531, and the FML was found to be the most important variable for determining the FIM. These results suggest that there is a need to determine the function of activities on the basis of the physical impairments of stroke patients. More variable measurement tools on the levels of body function and structure, as well as activity limitations are required.

The Effects of Health Behavior and Health Status on Heath-related Quality of Life in Older People: Gender Analysis by using the 2012 Korea Health Panel Data (건강행위와 건강상태가 노인의 건강 관련 삶의 질에 미치는 영향: 2012년 한국의료패널 자료를 이용한 성별 분석)

  • Park, Min-Jeong;Choi, So Eun
    • Research in Community and Public Health Nursing
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    • v.28 no.2
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    • pp.118-128
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    • 2017
  • Purpose: The purpose of this study is to measure health-related quality of life (HRQoL) and to investigate the affecting factors according to gender in older adults by using the 2012 Korea Health Panel data. Methods: The Korea Health Panel data 2012 were collected from February to August 2012 by Korea Institute for Health and Social Affairs and National Health Insurance Corporation and the number of respondents were 1,921. The data were analyzed by t-test, chi-square, Pearson correlation coefficient and multiple regression using SPSS/WIN program. Results: The limitation of activity was the most influential factor for health-related quality of life of both male and female. For male, the affecting factors on HRQoL were hearing problems and frustration. For female, the affecting factors on HRQoL were eating problems, depression and suicidal impulses. Drinking, moderate physical activities, vision problems and stress had a significant effect on HRQoL for both male and female. Conclusion: Health care providers should consider the differences between male and female when they design a program in order to improve HRQoL of older people.

A Study on the Developement of Soil Geochemical Exploration Method for Metal Ore Deposits Affected by Agricultural Activity (농경작업 영향지역의 금속광상에 대한 토양 지구화학 탐사법 개발 연구)

  • Kim, Oak-Bae;Lee, Moo-Sung
    • Economic and Environmental Geology
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    • v.25 no.2
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    • pp.145-151
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    • 1992
  • In order to study the optimum depth for the soil geochemical exploration in the area which is affected by agricultural activities and waste disposal of metal mine, the soil samples were sampled from the B layer of residual soil and vertical 7 layers up to 250 cm in the rice field and 3 layers up to 90 cm in the ordinary field. They were analyzed for Au, As, Cu, Pb and Zn by AAS, AAS-graphite furnace and ICP. To investigate the proper depth for the soil sampling in the contaminated area, the data were treated statistically by applying correlation coefficient, factor analysis and trend analysis. It is conclude that soil geochemical exploration method could be applied in the farm-land and a little contaminated area. The optimum depth of soil sampling is 60 cm in the ordinary field, and 150~200 cm in the rice field. Soil sampling in the area of a huge mine waste disposal is not recommendable. Plotting of geochemical map with factor scores as a input data shows a clear pattern compared with the map of indicater element such as As or Au. The second or third degree trend surface analysis is effective in inferring the continuity of vein in the area where the outcrop is invisible.

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Analysis and radiation dose assessment of 222Rn in indoor air at schools: Case study at Ulju County, Korea

  • Lee, ChoongWie;Choi, Sungyeol;Kim, Hee Reyoung
    • Nuclear Engineering and Technology
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    • v.50 no.5
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    • pp.806-813
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    • 2018
  • $^{222}Rn$ exists in nature in the form of a rare radioactive gas. In terms of environmental radiation, issues regarding $^{222}Rn$ have persisted because of its radiological hazardousness. Ulju County is one of the regions of Ulsan metropolitan city, with a population of 227,699. Ulju County has the highest density of industrial complexes in Korea. In this study, $^{222}Rn$ radioactivity concentration was measured and analyzed in 57 schools in Ulju County using 114 passive LR-115 type detectors to secure radiological safety and confirm basic information for reduction of resident exposure to $^{222}Rn$. The effective dose of $^{222}Rn$ was assessed to find the actual risk of the concentration surveyed in schools to human beings. The dose depended on four factors: subjects, $^{222}Rn$ concentration, dose coefficient, and time. The individuals subjected to dose estimation were classified into three types: students, teachers, and office workers. The subjects had different dwelling locations and times. The findings demonstrate that the radiological hazard to students and workers at schools in Ulju County owing to $^{222}Rn$ is negligible in terms of $^{222}Rn$ activity recommendation level.