• Title/Summary/Keyword: Activity Based Test

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Cell Viability and Antioxidant Enzyme Activity in the Cell of Ginseng (Panax ginseng C.A. Meyer) Treated with Soil Extracts (인삼재배지의 토양추출물이 종자 발아와 세포의 항산화효소 활성에 미치는 영향)

  • Ryu, Tae-Seok;Kwon, Soon-Tae
    • Korean Journal of Plant Resources
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    • v.21 no.4
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    • pp.324-328
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    • 2008
  • One hundred-eighty extracts of soil collected from ginseng (Panax ginseng C.A. Meyer) fields were subjected to lettuce germination test, electrolyte leakage, cell viability and antioxidant enzyme activity test. Regardless of various cultivation periods, there was no significant difference in soil pH, the content of organic matter and available phosphate in ginseng fields. Based on lettuce seed germination test, six soil extracts showing inhibition of germination and/or seedling growth were selected for further study. Selected soil extracts markedly inhibited cell viability of ginseng cultured cells but leakage of electrolytes were not affected by the treatment. Enzyme activity of superoxide dimutase in ginseng cultured cells was not affected by the treatment with the soil extracts. However, those of peroxidase and catalase were significantly inhibited by the treatment with soil extracts which showed inhibition of lettuce seed germination and seedling growth.

A Horticultural Therapy Program Focusing on Gardening Activities to Promote Psychological, Emotional and Social Health of the Elderly Living in a Homeless Living Facility for a Long Time: A Pilot Study

  • Kim, Yong Hyun;Lee, So-Hyeon;Park, Chul-Soo;Bae, Hwa-ok;Kim, Yun Jeong;Huh, Moo Ryong
    • Journal of People, Plants, and Environment
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    • v.23 no.5
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    • pp.565-576
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    • 2020
  • Background and objective: The elderly living in homeless living facilities for a long time suffer from various mental health problems. This study aims to determine the psychological, emotional, and social effects of a horticultural therapy program composed of gardening activities, which was designed based on the semantic structures of life for the homeless elderly living in the facilities for a long time. Methods: A total of 12 subjects (6 in the control group and 6 in the experimental group) participated in the study. The horticultural therapy program consisted mainly of gardening activities, and a total of 16 sessions were conducted once a week for 16 weeks, 60-90 minutes per session. The subjects were tested to evaluate their self-esteem, depression, and horticultural activities. The data were analyzed using the Mann-Whitney U test, Wilcoxon rank test, and Friedman test, which were nonparametric tests, conducted at a 95% significance level. Results: First, in the case of self-esteem, a significant difference was found between the groups, 20.00 points (SD = 5.69) in the control group, and 25.50 points (SD = 3.73) in the experimental group (p = .034). Second, in the case of depression, no statistically significant difference was found in the posttest. Finally, in the case of the horticultural activity evaluation, the scores of most variables gradually and significantly increased during the program [Verbal interaction during activity (p = .006), Self-concept and identity (p = .006), Need-drive adaptation (p < .001), Interpersonal and social relations (p < .001)]. Conclusion: These results support that the horticultural therapy program could help the elderly improve psychological relaxation, emotional stability, and social relationships. In order to generalize the results, it is suggested to increase the number of subjects or conduct additional repetitive experiments in further research.

A Study on the Application of Spatial Big Data from Social Networking Service for the Operation of Activity-Based Traffic Model (활동기반 교통모형 분석자료 구축을 위한 소셜네트워크 공간빅데이터 활용방안 연구)

  • Kim, Seung-Hyun;Kim, Joo-Young;Lee, Seung-Jae
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.15 no.4
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    • pp.44-53
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    • 2016
  • The era of Big Data has come and the importance of Big Data has been rapidly growing. The part of transportation, the Four-Step Travel Demand Model(FSTDM), a traditional Trip-Based Model(TBM) reaches its limit. In recent years, a traffic demand forecasting method using the Activity-Based Model(ABM) emerged as a new paradigm. Given that transportation means the spatial movement of people and goods in a certain period of time, transportation could be very closely associated with spatial data. So, I mined Spatial Big Data from SNS. After that, I analyzed the character of these data from SNS and test the reliability of the data through compared with the attributes of TBM. Finally, I built a database from SNS for the operation of ABM and manipulate an ABM simulator, then I consider the result. Through this research, I was successfully able to create a spatial database from SNS and I found possibilities to overcome technical limitations on using Spatial Big Data in the transportation planning process. Moreover, it was an opportunity to seek ways of further research development.

Iodine Quantification on Spectral Detector-Based Dual-Energy CT Enterography: Correlation with Crohn's Disease Activity Index and External Validation

  • Kim, Yeon Soo;Kim, Se Hyung;Ryu, Hwa Sung;Han, Joon Koo
    • Korean Journal of Radiology
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    • v.19 no.6
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    • pp.1077-1088
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    • 2018
  • Objective: To correlate CT parameters on detector-based dual-energy CT enterography (DECTE) with Crohn's disease activity index (CDAI) and externally validate quantitative CT parameters. Materials and Methods: Thirty-nine patients with CD were retrospectively enrolled. Two radiologists reviewed DECTE images by consensus for qualitative and quantitative CT features. CT attenuation and iodine concentration for the diseased bowel were also measured. Univariate statistical tests were used to evaluate whether there was a significant difference in CTE features between remission and active groups, on the basis of the CDAI score. Pearson's correlation test and multiple linear regression analyses were used to assess the correlation between quantitative CT parameters and CDAI. For external validation, an additional 33 consecutive patients were recruited. The correlation and concordance rate were calculated between real and estimated CDAI. Results: There were significant differences between remission and active groups in the bowel enhancement pattern, subjective degree of enhancement, mesenteric fat infiltration, comb sign, and obstruction (p < 0.05). Significant correlations were found between CDAI and quantitative CT parameters, including number of lesions (correlation coefficient, r = 0.573), bowel wall thickness (r = 0.477), iodine concentration (r = 0.744), and relative degree of enhancement (r = 0.541; p < 0.05). Iodine concentration remained the sole independent variable associated with CDAI in multivariate analysis (p = 0.001). The linear regression equation for CDAI (y) and iodine concentration (x) was y = 53.549x + 55.111. For validation patients, a significant correlation (r = 0.925; p < 0.001) and high concordance rate (87.9%, 29/33) were observed between real and estimated CDAIs. Conclusion: Iodine concentration, measured on detector-based DECTE, represents a convenient and reproducible biomarker to monitor disease activity in CD.

Biocompatibility and Bioactivity of Four Different Root Canal Sealers in Osteoblastic Cell Line MC3T3-El

  • Jun, Nu-Ri;Lee, Sun-Kyung;Lee, Sang-Im
    • Journal of dental hygiene science
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    • v.21 no.4
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    • pp.243-250
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    • 2021
  • Background: Endodontic sealers or their toxic components may become inflamed and lead to delayed wound healing when in direct contact with periapical tissues over an extended period. Moreover, an overfilled sealer can directly interact with adjacent tissues and may cause immediate necrosis or further resorption. Therefore, the treatment outcome conceivably depends on the endodontic sealer's biocompatibility and osteogenic potential. This study aimed to evaluate the cell viability and osteogenic effects of four different sealers in osteoblastic cells. Methods: AH Plus (resin-based sealer), Pulp Canal Sealer EWT (zinc oxide-eugenol sealer), BioRoot RCS (calcium silicate-based sealer), and Well-Root ST (MTA-based calcium silicate sealer) were mixed strictly according to the manufacturer's instructions, and dilutions of sealer extracts (1/2, 1/5 and 1/10) were determined. Cell viability was measured using the water-soluble tetrazolium-8 (WST-8) assay. Differentiation was assessed by alkaline phosphatase (ALP) activity and mineralized nodule formation by Alizarin Red S staining. Results: The cell viability of the extracts derived from the sealers excluding Well-Root ST was concentration dependent, with sealer extracts having the least viability at a 1/2 dilution. At sealer extract dilution of 1/10, the test groups showed the same survival rate as that control group, with the exception of BioRoot RCS. Among all experimental groups, BioRoot RCS showed the highest cell viability after 48 hours. The ALP activity was significantly higher in a concentration-dependent manner. Furthemore, all four materials promoted ALP activity and mineralized nodule formation compared to the control at 1/10 dilutions. Conclusion: This is the first study to highlight the differences in biological activity of these four materials. These results suggest that the composition of root canal sealers appears to alter the form of biocompatibility and osteoblastic differentiation.

Effects of Kinect-Based Mixed Reality Device on Physical Function and Quality of Life in Breast Cancer Survivors : A randomized controlled trial

  • Byung-Gul Lim;Xinxing Li;Yun-Ho Sung;Si-Woo LEE;Hyun-Jun Kim;Wook Song
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.2
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    • pp.49-60
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    • 2023
  • Purpose : We aimed to evaluate the impact of a exercise with kinect-based mixed reality device (KMR) on physical function, upper extremity disability, fatigue, and quality of life in breast cancer survivors. We hypothesized that this exercise program would improve physical function, physical activity, fatigue, and quality of life. Methods : Thirty-nine breast cancer survivors were randomized to either the KMR exercise group (KE) or the home stretch group (HS). The KE participated in 8 weeks of exercise, exercising 3 times per week, while the HS performed 8 weeks of stretching exercises, also 3 times per week. Before and after the intervention period, participants underwent assessments of physical function, including body composition, chester step test (CST), and hand grip strength (HGS). Additionally, participants completed questionnaires including the international physical activity questionnaire (IPAQ), disabilities of the arm, shoulder and hand (DASH) questionnaire, and functional assessment of cancer therapy-breast (FACT-B) questionnaire to measure their physical activity levels, upper extremity disability, and quality of life, respectively. Results : Overall, significant improvements were observed in several shoulder movements, body weight, and physical activity, with no significant interaction effects between groups and time. Furthermore, there was a significant group by time interaction for body weight, left flexion, right flexion, right abduction, and left adduction, as well as for upper extremity disability (K-DASH) and quality of life (FACT-B). Conclusion : In conclusion, the KMR exercise program was found to be effective at improving physical function, upper extremity disability, quality of life, and overall well-being in breast cancer survivors. The significant improvements observed in multiple measures and the significant group by time interactions for various outcomes highlight the potential benefits of this KMR exercise program in promoting a better quality of life for breast cancer survivors.

Evaluation Tools for Patients with Neurologic Disorders Based on the ICF Model: A Survey of Korean Physical Therapists (ICF 모델 기반 신경계 환자 물리치료 평가 도구 사용 조사)

  • Lee, Ji-ah;Woo, Yong-Keun;Won, Jong-Im;Kim, Su-jin
    • PNF and Movement
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    • v.20 no.3
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    • pp.359-370
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    • 2022
  • Purpose: Physical therapists are required to properly choose the most appropriate treatment for each patient within the framework of the International Classification of Functioning, Disability, and Health (ICF model). The aims of this study were to determine whether neurological physical therapists in clinical settings in South Korea know about the ICF model and to investigate the current trends of outcome measures (OMs) used by them. Methods: Two hundred and one physical therapists who worked with patients with neurological disorders participated in this study. The survey was conducted via e-mail and asked about commonly used OMs and the considerations for selecting OMs. Results: All physical therapists involved in this study responded completely, and 45.8% of participants learned about the ICF model, while 37.3% understood the detailed information related to the ICF model. The rest of the participants did not know or just heard about the ICF model. The most frequently used tools at the body function/structure level were the Range of Motion (98%), Manual Muscle Test (97%), Berg Balance Scale (83.1%), and Modified Ashworth Scale (70.6%) when allowing repetition. At the activity level, the 10-meter walk test (71.1%), 6-minute walk test (54.2%), and Functional Ambulatory Category (43.3%) were used, while the Activity-Specific Balance Confidence Scale (23.9%) was used at the participation level. There was a positive relationship between the number of tools used and years of work, as well as the level of understanding of the ICF model. Conclusion: The results of this study suggest that it is necessary to learn the ICF model in a clinical setting. In addition, the medical system needs to be modified to encourage physical therapists in South Korea to use proper OMs within the ICF model.

Relationship between Handgrip Strength and Cardiopulmonary Fitness in Patients with Myocardial Infarction (심근 경색 환자에서의 손의 근력과 심폐기능의 연관성)

  • Kim, JiHee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.10
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    • pp.506-514
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    • 2018
  • This study was conducted to investigate the relationship between hand grip strength and cardiopulmonary fitness in patients with myocardial infarction. In this retrospective study, 67 patients who experienced myocardial infarction for 10 months were analyzed. Hand grip strength was measured using a handheld dynamometer. Dynapenia was diagnosed based on a dominant hand grip strength of less than 30 kg for males and 20 kg for females. A cardiopulmonary exercise test was performed using a treadmill. Physical activity status was also evaluated. Cardiorespiratory fitness parameters were analyzed using a t-test and a Mann-Whitney test. VO2max, METmax, and exercise time significantly decreased in the dynapenia group compared with the non-dynapenia group. Correlation analysis revealed that dominant handgrip strength was significantly related to cardiorespiratory fitness parameters. Moreover, VO2max, METmax, and exercise time were significantly increased in patients with vigorous activity compared with the sedentary group. These findings indicate that handgrip strength could potentially be used as a marker of cardiorespiratory functions. Accordingly, patients with myocardial infarction should be evaluated for grip strength and physical activity, and we can encourage patients to participate actively in cardiac rehabilitation.

Educational Intervention Based on the Health Belief Model to Modify Risk Factors of Cardiovascular Disease in Police Officers in Iran: A Quasi-experimental Study

  • Saffari, Mohsen;Sanaeinasab, Hormoz;Jafarzadeh, Hassan;Sepandi, Mojtaba;O'Garo, Keisha-Gaye N.;Koenig, Harold G.;Pakpour, Amir H.
    • Journal of Preventive Medicine and Public Health
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    • v.53 no.4
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    • pp.275-284
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    • 2020
  • Objectives: Police officers may be at a greater risk for cardiovascular disease (CVD) than the general population due to their highstress occupation. This study evaluated how an educational program based on the health belief model (HBM) may protect police officers from developing CVD. Methods: In this single-group experimental study, 58 police officers in Iran participated in a 5-week intervention based on HBM principles. Outcomes included changes in scores on an HBM scale, time spent on moderate to vigorous physical activity (International Physical Activity Questionnaire), body mass index (BMI), blood lipid profile, blood glucose, and blood pressure. The intervention consisted of 5 HBM-based educational sessions. Follow-up was conducted at 3 months post-intervention. The paired t-test was used to examine differences between baseline and follow-up scores. Results: All aspects of the HBM scale improved between baseline and follow-up (p<0.05), except the cues to action subscale. Self-efficacy and preventive behaviors improved the most. BMI decreased from 26.7±2.9 kg/㎡ at baseline to 25.8±2.4 kg/㎡ at follow-up. All components of the lipid profile, including triglycerides, cholesterol, high-density lipoprotein, and low-density lipoprotein, showed significant improvements post-intervention. Blood glucose and blood pressure also decreased, but not significantly. Nearly 25% of participants who were not physically active at baseline increased their physical activity above or beyond the healthy threshold. Conclusions: A relatively brief educational intervention based on HBM principles led to a significant improvement in CVD risk factors among police officers. Further research is needed to corroborate the effectiveness of this intervention.

A Novel Method for Survivability Test Based on End Nodes in Large Scale Network

  • Ming, Liang;Zhao, Gang;Wang, Dongxia;Huang, Minhuan;Li, Xiang;Miao, Qing;Xu, Fei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.2
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    • pp.620-636
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    • 2015
  • Survivability is a necessary property of network system in disturbed environment. Recovery ability is a key actor of survivability. This paper concludes network survivability into a novel composite metric, i.e. Network Recovery Degree (NRD). In order to measure this metric in quantity, a concept of Source-Destination Pair (SD Pair), is created to abstract end-to-end activity based on end nodes in network, and the quality of SD Pair is also used to describe network performance, such as connectivity, quality of service, link degree, and so on. After that, a Survivability Test method in large scale Network based on SD pairs, called STNSD, is provided. How to select SD Pairs effectively in large scale network is also provided. We set up simulation environment to validate the test method in a severe destroy scenario and evaluate the method scalability in different large scale network scenarios. Experiment and analysis shows that the metric NRD correctly reflects the effort of different survivability strategy, and the proposed test method STNSD has good scalability and can be used to test and evaluate quantitative survivability in large scale network.