• Natural Product Sciences
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• v.23 no.1
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• pp.5-8
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• 2017

An antimicrobial compound has been isolated from the leaves of Glochidion superbum. The compound was determined as methyl 3, 4, 5-trihydroxybenzoate (methyl gallate), based on ultraviolet (UV), infrared (IR), nuclear magnetic resonance (NMR) and mass spectroscopy (MS) analysis. The isolated compound exhibited potent antimicrobial activity against three clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) by qualitative agar disc diffusion method and quantitative broth dilution method. Agar disc diffusion was done in a dose-dependent manner for each bacterial isolate at disc potencies of 25, 50, 100, and $150{\mu}g/disc$. The zones of inhibition were on average equal to 12.27, 14.20, 15.43, and 24.17 mm respectively. The inhibition zones were compared with that of vancomycin disc at $30{\mu}g$ as a reference standard. The MIC and MBC values were $50{\mu}g/ml$ and $100{\mu}g/ml$ respectively. The results of anti MRSA activity were analyzed using one-way ANOVA with Turkey's HSD and Duncan test. In conclusion, methyl gallate which was isolated from G. superbum showed the inhibition activity against methicillin resistant S. aureus.

• Bulletin of the Korean Chemical Society
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• v.30 no.11
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• pp.2749-2753
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• 2009

Structural characteristics that influence on the insecticidal activity ($pI_{50}$) of 2-(n-octyl)isothiourea analogues (1-45) against the diamondback moth (Plutella xylostella, L.) based on three dimensional quantitative structure activity relationships (3D-QSARs) were discussed quantitatively using a comparative molecular field analysis (CoMFA) and a comparative molecular similarity indeces analysis (CoMSIA) methods. The statistical values of the CoMFA 2 model were better than those of the CoMSIA 1 model. The CoMFA 2 model was the optimized model with the correlativity (the training set: Ave. = 0.104 & PRESS = 0.613) and the predictability (the test set: Ave. = 0.086 & PRESS = 0.096). Insecticidal activities with the optimized CoMFA 2 model were dependent upon steric factors (79.4%) of $R_1-R_3$ substituents. From the analytical results of CoMFA contour maps, it is predicted that the R1 substituent of 1-45 which has a steric favor in a broad space, $R_2\;and\;R_3$ groups with a steric favor in a narrow space and a H-bond donor favor would have better the insecticidal activity.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.37 no.2
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• pp.161-169
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• 2011

To develop a new natural cosmetic hair care product for scalp treatment, we investigated the effect of enzyme modified (Viscozyme, Pectinex) oriental medical prescriptions on hair growth and melanogenesis. Enzyme modified oriental medical prescriptions showed the antioxidative effect, inhibitory effects on lipoxygenase activity and $5{\alpha}$-reductase activity and melanogenic activity. In human irritation test, they did not show any adverse effect. Based on these results, we suggest that enzyme modified oriental medical prescriptions may potentially be used in a cosmeceutical hair care product for scalp treatment.

• Physical Therapy Rehabilitation Science
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• v.10 no.2
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• pp.98-105
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• 2021

Objective: The purpose of this study was to examined the kinematic relationship and differences through the range of motion (ROM), muscle activity, and vertical ground reaction force (VGRF) during forward and backward lunge movements, which are effective in improving muscle strength and balance ability of the lower extremities, and to provide clinical information on more efficient lunge movements. Design: Cross-sectional study Methods: Fifteen adult males who met the selection criteria were tested for their dominant feet.Forward and backward lunges were then performed, and the ROM, muscle activity, and VGRF were measured for kinematic analysis during the lunge movement.The differences betweenthe forward lunge and backward lunge intervention were examined using a paired t-test. Results: A significant increase in the ROM of the knee and ankle was observed during the forward and backward lunges (p<0.05). In addition, in terms of the muscle activity, the peak values of the vastus medialis oblique (VMO) and VGRF also showed a significant increase in the forward lunge compared to the backward lunge (p<0.05). Conclusions: This study showed an increase in VGRF peak value, knee and ankle ROM, and VMO muscle activity during forward lunge. Based on these results, it is considered necessary to apply differently depending on the direction of progress in consideration of the musculoskeletal situation and physical ability during the lunge movement.

• PNF and Movement
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• v.21 no.3
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• pp.319-326
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• 2023

Purpose: The purpose of this study was to investigate the effects of modified ankle movement patterns on participants' active dorsiflexion range of motion and leg muscle activity. Methods: This study recruited twenty-five participants, all of whom were healthy individuals with no abnormalities in the ankle or knee joints. The research methodology involved measuring the active dorsiflexion range of motion and muscle activity in each person's legs based on the presence or absence of toe extension while the subjects were in a comfortable, supine position. A statistical analysis was conducted using SPSS 25.0, and a paired samples t-test was employed. The significance level was set at 0.05. Results: When the participants demonstrated the modified ankle movement pattern with a controlled toe grip, there was an increase in their active dorsiflexion angle. However, during the proprioceptive neuromuscular facilitation technique without a controlled toe grip, a higher level of activity was observed in the leg muscles. Conclusion: The results of this study could be used as foundational data for establishing a rehabilitation exercise program designed to enhance range of motion and muscle activation in the ankle joint.

• The Journal of the Acoustical Society of Korea
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• v.30 no.7
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• pp.396-401
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• 2011

In this paper, we propose a novel voice activity detection (VAD) algorithm to effectively distinguish speech from nonspeech in various noisy environments. The presented VAD utilizes the power spectral deviation (PSD) based on Teager energy (TE) instead of the conventional PSD scheme to improve the performance of decision for speech segments. In addition, the speech absence probability (SAP) is derived in each frequency subband to modify the PSD for further VAD. Performances of the proposed VAD algorithm are evaluated by objective test under various environments and better results compared with the conventional methods are obtained.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.9 no.5
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• pp.986-994
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• 2005

This Paper proposes the likelihood-based nonlinear dimension reduction method of the speech feature parameters in order to construct the voice activity detecter adaptable in noisy environment. The proposed method uses the nonlinear values of the Gaussian probability density function with the new parameters for the speec/nonspeech class. We adapted Likelihood Ratio Test to find speech part and compared its performance with that of Linear Discriminant Analysis technique. In experiments we found that the proposed method has the similar results to that of Gaussian Mixture Models.

• Journal of the Korean Society of Costume
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• v.66 no.6
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• pp.32-45
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• 2016

The purpose of this study is to propose changes that can be made to improve nurse uniforms in terms of outfit and functionality based on actual wearing conditions and nurse's preference. The proposed nurse uniform was composed of a blouse and pants. The design was as follows: the blouse had short set-in sleeve with China collar, a princess line, and it came down to middle hip. Armhole action pleats and back inverted pleats were embedded for convenient arm movements. The pants waist had a rubber band at the back waist, and the crotch length and the knee width were increased for activity. To make the pocket more accommodative, separate pocket slots treated with silicone were added to prevent belongings from coming out of the pocket. The pink tone of the uniforms, as well as the stripes on the blouses and spandex incorporated pants were based on nurses' preference. the nurse uniforms were produced after measuring the size of women in the age of 25 to 29, and the uniform patterns were corrected after two wearing experiments. Wearing test was examined in terms of appearance and functionality. For appearance, experts gave the uniforms a mean rating of 4.30, and nurses gave a mean rating of 4.00. Functionality was evaluated in terms of ease of activity and storage aspects. The total mean of ease of activity in nursing service was 4.30, whereas the evaluation of storage in terms of pocket position and convenience was 3.80.

• International Journal of Advanced Culture Technology
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• v.10 no.1
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• pp.180-186
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• 2022

This study is a pilot study to confirm the effectiveness of training after applying emergency simulation training for inactive nurses and to present a new model of simulation training operation method. In this study, the control group is a group that directly participates in the simulation activity, and the experimental group is the group that observes the control group's simulation activity. Experimental group and control group were matched 1:1 to experience all the roles of the resuscitation team. The study participants were 5 inactive nurses in the experimental group and 5 inactive nurses in the control group, and the total training time was 5 hours. The emergency simulation operation composition consists of theory education, skill education, and simulation. The interview was conducted. The educational satisfaction of the participants was 4.65 points for theory education and 4.70 points for practical education based on 5 points. Participants' performance confidence improved from 3.60 points before operation to 7.20 points after operation. Emergency simulation operation consisted of pre-test, theory education, skill education, simulation implementation, debriefing, and post-test. Participants expressed that the choice of group greatly reduced the burden and anxiety about performing the role of the resuscitation team. However, difficulties and inexperience in the operation of the defibrillator were reported in the experimental group. The control group reported that the simulation activity of the experimental group was not significantly different from theirs. Through the results of this study, it was confirmed that emergency simulation education not only reduced the burden and anxiety of inactive nurses, but also had an effect of education. Based on the research results, it is proposed to expand the participants and verify the effectiveness of education through specific variables such as learning commitment, learner confidence, simulation satisfaction, and team effectiveness.

• Korean Journal of Food Science and Technology
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• v.40 no.1
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• pp.21-30
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• 2008

In this study, the antioxidant activities of 27 medicinal herbs and plants were measured. The dried medicinal herbs and plants were pulverized and extracted by water, 15% ethanol, and 45% ethanol, respectively at above $80^{circ}C$ for 90 minutes. The original and diluted extracts were tested for their antioxidant activities by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging activity assay. Cornus officinalis (C) and Scutellaria baicalensis (S) were selected to develop rice wines with higher antioxidant activities, based on the result of the 45% ethanol extraction. The rice wine developed using sample showed the highest antioxidant activity as comparing to those of other commercial rice wines. The rice wine samples were analyzed for titratable acidity, pH, $^{\circ}Brix$, reducing sugar content, color (L, a, b), amino-acidity, and ultraviolet absorption. The preferences for color, aroma, and overall acceptability were determined using a 9-point hedonic scale by 150 consumers. The sweetness, sourness, fruitiness, color, and medicinal herb-taste levels of the developed rice wines were also evaluated, using a 9-point just-about-right scale. The mean overall acceptability score of c (5.54) was higher than that of sample S. Based on the results, the sourness and medicinal herb-taste levels of sample s should be modified to higher levels, and the fruitiness of sample S also needs to be adjusted. For a future study, the final compositions of the developed rice wines will be adjusted for product launching based on the preference test data acquired in this study.