• Title/Summary/Keyword: Active unit

Search Result 737, Processing Time 0.05 seconds

The Design of Photobiological Active Molecular Model For Photodynamic Therapy

  • Choi, Chang-Shik
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2019.05a
    • /
    • pp.521-524
    • /
    • 2019
  • The design of photobiological active photosensitizing molecular model for photodynamic therapy has been attracted as a research for the development of cancer treatment, and has been interested in the effective method for cancer treatment and the photosensitizer having more stable wavelength. Furthermore, the development of photosensitizer has been already carried out from the first generation molecule to the third one, and the research of smart photosensitizer as the fourth generation has been requested. As a fact, the selective killing of the only cancer cell is very difficult problem, and the present photodynamic therapy has the problem of killing of the normal cell. So, I have designed the new modelling of photosensitizer having the smart recognizing unit and the magnetic nanoparticle as well as having the several effective recognizing unit. In particular, the new model design of the photosensitizer having lanthanide metal has suggested for the development of photodynamic therapy. The model design of these new photosensitizing molecules will be introduced in the poster section for the new turning point of the development of photosensitizer.

  • PDF

Development of High Speed Digital Signal Processing Unit for Active Control of Noise Fields in Passenger Car (자동차 실내소음의 능동제어를 위한 고속 이산 신호처리 장치 개발)

  • 김인수;이강모;허현무;홍석윤
    • Journal of KSNVE
    • /
    • v.6 no.2
    • /
    • pp.205-214
    • /
    • 1996
  • Active noise control(ANC) requires the full capability of a modern digital signal processing module. This paper describes the digital signal processing unit which is designed for ANC of noise fields in passenger car. System hardware is designed to allow software controlled versatility as well as fully qutomatic operation. The developed system is provided with the ability to be self-operated except the case of upload/download of data and program between the personal computer and the system memory. Experimental results are presented to demonstrate ANC performance of noise fields in lightly damped enclosure and passenger car.

  • PDF

Experimental Study of Design for Semi - Active suspension system for Railway Vehicle with narrow gauge (협궤 차량용 준능동형 현가 시스템 설계의 시험적 연구)

  • Lee Nam-Jin;Kim Chul-Gun;Nam Hak-Gi
    • Proceedings of the KSR Conference
    • /
    • 2005.11a
    • /
    • pp.811-815
    • /
    • 2005
  • Traditional passive suspension has limitations to meet the required specifications of high level trains, and so Active suspension system is proposed to meet the requirements with active components which could be controlled by external signal for optimized behavior of train. Active suspension is to be divided by Full active suspension and Semi-active suspension whether using the external power source or not, and though the performance of Semi-Active suspension is worse than Full one. Semi-active suspension is focused with its effectiveness per cost. Semi-Active suspension system consists of sensors, ECU (electrical control unit), and variable damper, which are to be designed to be fit for train system. And the software of ECU is to be developed for to be suited to its dynamic behavior through simulation result calculated by proven model. In this experimental study, the hardware and software of semi-active suspension system is to be realized and its performance for improvement of ride quality to be confirmed through roller rig test.

  • PDF

Effects of Korean ginseng berry on skin antipigmentation and antiaging via FoxO3a activation

  • Kim, Juewon;Cho, Si Young;Kim, Su Hwan;Cho, Donghyun;Kim, Sunmi;Park, Chan-Woong;Shimizu, Takahiko;Cho, Jae Youl;Seo, Dae Bang;Shin, Song Seok
    • Journal of Ginseng Research
    • /
    • v.41 no.3
    • /
    • pp.277-283
    • /
    • 2017
  • Background: The ginseng berry has various bioactivities, including antidiabetic, anticancer, antiinflammatory, and antioxidative properties. Moreover, we have revealed that the active antiaging component of the ginseng berry, syringaresinol, has the ability to stimulate longevity via gene activation. Despite the many known beneficial effects of ginseng, its effects on skin aging are poorly understood. In this study, we investigated the effects of ginseng and the ginseng berry on one of the skin aging processes, melanogenesis, and age-related pigment lipofuscin accumulation, to elucidate the mechanism of action with respect to antiaging. Methods: The human melanoma MNT1 cell line was treated with ginseng root extract, ginseng berry extract, or syringaresinol. Then, the cells were analyzed using a melanin assay, and the tyrosinase activity was estimated. The Caenorhabditis elegans wild type N2 strain was used for the life span assay to analyze the antiaging effects of the samples. A lipofuscin fluorescence assay was performed during 10 passages with the syringaresinol treatment. Results: A 7-d treatment with ginseng berry extract reduced melanin accumulation and tyrosinase activity more than ginseng root extract. These results may be due to the active compound of the ginseng berry, syringaresinol. The antimelanogenic activity was strongly coordinated with the activation of the longevity gene foxo3a. Moreover, the ginseng berry extract had more potent antiaging effects, caused a life span extension, and reduced lipofuscin accumulation. Conclusion: Taken together, our results suggest that these antimelanogenic effects and antiaging effects of ginseng berry mediate the activation of antioxidation-FoxO3a signaling.

Agreement of Manual Muscle Testing and Test-Retest Reliability of Hand Held Dynamometer for the Posterior Gluteus Medius Muscle for Patients With Low Back Pain (요통 환자를 대상으로 후중둔근 도수근력검사의 일치도 및 휴대용 근력계 측정 방법의 신뢰도 검사)

  • Park, Kyue-Nam;Kim, Hyun-Sook;Choi, Houng-Sik;Lee, Won-Hwee;Ha, Sung-Min;Kim, Su-Jung
    • Physical Therapy Korea
    • /
    • v.18 no.3
    • /
    • pp.67-75
    • /
    • 2011
  • The purpose of this study was to assess the agreement of manual muscle testing (MMT) and test-retest reliability of a hand held dynamometer for the posterior gluteus medius muscle, with and without lumbar stabilization, using a pressure biofeedback unit for patients with low back pain. The pressure biofeedback unit was used to minimize the substitute motion of the lumbopelvic region during hip abduction in patients lying on their side. Fifteen patients with low back pain participated in this study. A tester determined the MMT grades of the posterior gluteus medius with and without the pressure biofeedback unit. Active hip abduction range of motion with an inclinometer and the strength of their posterior gluteus medius using a hand held dynamometer were measured with and without the pressure biofeedback unit in the MMT position. The agreement of the grade of muscle strength in the MMT, and intra-rater reliability of both the active hip abduction range of motion and the strength of posterior gluteus medius were analyzed using the weighted kappa and intraclass correlation coefficient (ICC), respectively. The agreement of MMT with the pressure biofeedback unit (weighted kappa=.92) was higher than the MMT (weighted kappa=.34)(p<.05). The inclinometer with pressure biofeedback unit measurement of the active hip abduction range of motion had an excellent intra-rater reliability (ICC=.90). Also, the hand held dynamometer with pressure biofeedback unit measure of strength of the posterior gluteus medius had a good intra-rater reliability (ICC=.85). Therefore, the test for muscle strength with pressure biofeedback unit will be a reliable method for the determination of the MMT grades or amount of posterior gluteus medius muscle strength and the measurement of the range of motion for hip abduction in patients with low back pain.

A Study on the Derivation of the Unit Hydrograph using Multiple Regression Model (다중회귀모형으로 추정된 모수에 의한 최적단위유량도의 유도에 관한 연구)

  • 이종남;김채원;황창현
    • Water for future
    • /
    • v.25 no.1
    • /
    • pp.93-100
    • /
    • 1992
  • A study on the Derivation of the Unit Hydrograph using Multiple Regression Moe이. The purpose of this study is to deriver an optimal unit hydrograph suing the multiple regression model, particularly when only small amount of data is available. The presence of multicollinearity among the input data can cause serious oscillations in the derivation of the unit hydrograph. In this case, the oscillations in the unit hydrograph ordinate are eliminated by combining the data. The data used in this study are based upon the collection and arrangement of rainfall-runoff data(1977-1989) at the Soyang-river Dam site. When the matrix X is the rainfall series, the condition number and the reciprocal of the minimum eigenvalue of XTX are calculated by the Jacobi an method, and are compared with the oscillation in the unit hydrograph. The optimal unit hydrograph is derived by combining the numerous rainfall-runoff data. The conclusions are as follows; 1)The oscillations in the derived unit hydrograph are reduced by combining the data from each flood event. 2) The reciprocals of the minimum eigen\value of XTX, 1/k and the condition number CN are increased when the oscillations are active in the derived unit hydrograph. 3)The parameter estimates are validated by extending the model to the Soyang river Dam site with elimination of the autocorrelation in the disturbances. Finally, this paper illustrates the application of the multiple regression model to drive an optimal unit hydrograph dealing with the multicollinearity and the autocorrelation which cause some problems.

  • PDF

A Novel Picometer Positioning System for Machine Tools and Measuring Machines

  • Mizumoto, Hiroshi;Yabuta, Yoshito;Arii, Shiroh;Tazoe, Yoichi;Kami, Yoshihiro
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 2005.06a
    • /
    • pp.123-128
    • /
    • 2005
  • A novel tri-mode ultraprecision positioning system for machine tools and measuring machine is proposed. The basic coarse mode uses a Twist-roller Friction Drive (abbr. TFD), and controls several tens of millimeters of the machine-table travel with nanometer order of positioning resolution. The fine mode also utilizes the TFD with a fine adjusting mechanism. The resolution of the fine mode is in the range of sub-nanometer. For realizing picometer positioning, the ultra-fine mode is executed by using an active aerostatic guideway. On the bearing surface of this active guideway, several Active Inherent Restrictors (abbr. AIRs) are embedded for controlling the table position. An AIR unit consists of a piezoelectric actuator having a through hole, one end of the hole on the bearing surface acts as an inherent restrictor. Owing to the aerostatic mechanism of the AIR, the deformation of the piezoelectric actuator in the AIR unit causes much reduced table displacement. Such motion reduction is effective for ultraprecision positioning. Current positioning resolution of the ultra-fine mode is 50pm, however the final goal of the positioning resolution is expected to be in the order of picometer.

  • PDF

Evaluation of Information Presentation Methods for a Wearable Braille Display

  • Jung, Ki-Hyo;Lee, Min-Jeong;Chang, Joon-Ho;You, Hee-Cheon
    • Journal of the Ergonomics Society of Korea
    • /
    • v.30 no.6
    • /
    • pp.739-747
    • /
    • 2011
  • Objective: The present study evaluated information presentation methods applicable to a wearable Braille display in terms of performance and satisfaction measures. Background: A Braille display wearable at a finger can improve accessibility of information for the blind by presenting information in real time. Method: A Braille display with six pins operated by DC servomotors was developed to simulate four information presentation methods(active, stationary, simultaneous, and sequential methods). An evaluation experiment was conducted with 16 participants(8 normal and 8 blind participants) by using three objective measures(reaction time, RT, unit: sec; recognition time, CT, unit: sec; correct response percentage, CP) and two subjective measures(overall satisfaction, OS; perception easiness, PE) with a 7-point scale. Results: The average RTs and CTs of the active and stationary methods were significantly shorter than those of the simultaneous and sequential methods for the blind participants. Also, the average CPs, OSs, and PEs of the active and sequential methods were significantly higher than those of the stationary and simultaneous methods. Conclusion: The active and sequential methods were preferred to the other methods for the blind. Application: The performance characteristics identified in the present study for the four braille display methods can be utilized to develop an effective wearable Braille display system.

Low-computation Motion Tracker Unit Linkable to Video Codec for Object Tracking Camera (동영상 코덱과 연동이 가능한 객체 추적 카메라용 저연산량 움직임 추적기)

  • Yang, Hyeon-Cheol;Lee, Seong-Soo
    • Journal of the Institute of Electronics Engineers of Korea SD
    • /
    • v.45 no.10
    • /
    • pp.66-74
    • /
    • 2008
  • Surveillance system using active tracking camera has no distance limitation of surveillance range compared to supersonic or sound sensors. However, complex motion tracking algorithm requires huge amount of computation. Compared to conventional methods using DSPs or embedded processors, this paper proposes and implements a novel motion tracker unit that detects and extracts motion information of moving objects by using picture difference of consecutive frames. The proposed motion tracker unit was implemented in FPGA with about 13,000 gates. It processes NTSC format video and was verified by embedding it into the active surveillance camera system. We also propose and implements a motion estimator unit linkable to video codec by embedding the proposed motion tracker unit into ready-made motion estimator unit. The implemented motion estimator unit is about 17,000 gates in $0.35{\mu}m$ process.

A study on Propulsion Fuel consumption rate for orbit maintenance of LEO

  • 정도희;공창덕
    • Proceedings of the Korean Society of Propulsion Engineers Conference
    • /
    • 2000.11a
    • /
    • pp.10-10
    • /
    • 2000
  • For low Earth orbit, the atmosphere causes orbit altitude to decrease, If this decrease is not corrected by the satellite propulsive unit, the orbit decoys continuously unit reaches the dense atmosphere and satellite life ends. If active orbit maintenance is mode by satellite propulsive unit then fuel consumption is necessary, which must be considered in the satellite design. Especially interesting is the method for evaluating the fuel consumption role for maintenance of elliptical orbit developed in this paper.(omitted)

  • PDF