• 제목/요약/키워드: Activation process

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Post-transcriptional Regulation of NK Cell Activation

  • Kim, Tae-Don;Park, Ju-Yeong;Choi, In-Pyo
    • IMMUNE NETWORK
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    • 제9권4호
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    • pp.115-121
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    • 2009
  • Natural killer (NK) cells play key roles in innate and adaptive immune defenses. NK cell responses are mediated by two major mechanisms: the direct cytolysis of target cells, and immune regulation by production of various cytokines. Many previous reports show that the complex NK cell activation process requires de novo gene expression regulated at both transcriptional and post-transcriptional levels. Specialized un-translated regions (UTR) of mRNAs are the main mechanisms of post-transcriptional regulation. Analysis of posttranscriptional regulation is needed to clearly understand NK cell biology and, furthermore, harness the power of NK cells for therapeutic aims. This review summarizes the current understanding of mRNA metabolism during NK cell activation, focusing primarily on post-transcriptional regulation.

Preparation and Characterization of Carbon Nanotubes-Based Composite Electrodes for Electric Double Layer Capacitors

  • Seo, Min-Kang;Park, Soo-Jin
    • Bulletin of the Korean Chemical Society
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    • 제33권5호
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    • pp.1523-1526
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    • 2012
  • In this work, we prepared activated multi-walled carbon nanotubes/polyacrylonitrile (A-MWCNTs/C) composites by film casting and activation method. Electrochemical properties of the composites were investigated in terms of serving as MWCNTs-based electrode materials for electric double layer capacitors (EDLCs). As a result, the A-MWCNTs/C composites had much higher BET specific surface area, and pore volume, and lower volume ratio of micropores than those of pristine MWCNTs/PAN ones. Furthermore, some functional groups were added on the surface of the A-MWCNTs/C composites. The specific capacitance of the A-MWCNTs/C composites was more than 4.5 times that of the pristine ones at 0.1 V discharging voltage owing to the changes of the structure and surface characteristics of the MWCNTs by activation process.

Effects of Culture Conditions on The Expression of Cyclin B1 Protein during the First Meiotic Maturation in Bovine Immature Oocytes

  • Hwang Seong-Soo;Yoon Jong-Taek
    • Reproductive and Developmental Biology
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    • 제30권2호
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    • pp.115-118
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    • 2006
  • Cyclin B1 is known to reflect the M-phase promoting factor (MPF), a universal regulator of G2/M-phase transition, activity during the process of oocytes maturation. To investigate whether culture condition affects the maturation rate and the expression of cyclin B1 protein, bovine immature oocytes are stimulated and cultured according to the following protocols: Experiment 1: denuded oocytes (denude) only, COC only, denuded oocytes+granulosa cells (denude+GCs) and COC+GCs; Experiment 2: no-activation (control), 7% ethanol for 5 min and $10{\mu}l/ml$ ionomycin for 5 min at immediately before maturation. The maturation rates of denude and no-activation group were significantly lower in both experiments (P<0.05), respectively. Co-culture or stimulation method in bovine immature oocytes culture increases the cyclin B1 expression significantly in both experiments (P<0.05). Based on these results, culture condition affects the maturation rate and the expression of cyclin B1 protein during the first meiotic maturation in bovine immature oocytes.

국내 기업간 전자상거래 활성화를 위한 정부 역할에 관한 연구 (A theoretical study on the role of government for the activation of B2B in Korea)

  • 백종구
    • 한국콘텐츠학회논문지
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    • 제2권1호
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    • pp.46-51
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    • 2002
  • 인터넷의 발전과 더불어 많은 기업이 생산성을 향상하고 경쟁적 우의를 제고하는 한편 전세계적으로 고객의 저변확대를 하고 있다. 전자상거래의 도입 .확산과 관련하여 정부가 개입해야 할 필요성은 전자상거래가 미치는 파급효과에서 찾을 수 있다. 전자상거래가 경제적으로 미치는 가장 큰 파급효과는 일반적으로 사회 전반적인 거래비용의 절감으로 보고 있다. 이러한 시점에서, 본 연구는 기업간 전자상거래의 활성화에 영향을 주는 주요성공요인 분석을 통해 정부의 주도적인 역할이 필요한 세 가지 측면의 주요성공요인을 도출하고, 각 측면에서의 정부의 역할 및 정책 방안을 제안하고 있다.

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추진제 성형에 관한 기초연구 (제2보). 우레탄 중합에 미치는 첨가제 효과 (Basic Studies on Propellant Casting (II). Effects of Solid Additives on Urethane Polymerization)

  • 전용구;이익춘;김시준
    • 대한화학회지
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    • 제25권4호
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    • pp.214-218
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    • 1981
  • Solid인 Hexogen 존재하에서 hydroxyl-terminated polybutadiene과 isophorone diisocyanate의 혼성중합반응속도에 관하여 연구하였다. 중합반응속도는 Hexogen의 첨가량이 증가할 수록 빠르게 나타났지만, Hexogen의 촉매적 역할은 없었으며, 오직 entropy control에 의한 반응임을 밝혔다. 이 반응은 2차 반응속도법칙에 잘 일치하며, activation energy는 8.4 Kcal/mole로 거의 일정하다.

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Synthesis of Fe-TiB2 Nanocomposite by a combination of mechanical activation and heat treatment

  • ;;김지순;강태훈;김진천;권영순
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2012년도 춘계학술발표대회
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    • pp.91.2-91.2
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    • 2012
  • The TiB2-reinforced iron matrix nanocomposite (Fe-TiB2) was in-situ fabricated from titanium hydride (TiH2) and iron boride (FeB) powders by a simple and cost-effective process that combines the mechanical activation (MA) and a subsequent heat treatment (HT). Effect of milling factors and synthesized temperatures on the formation of the nanocomposite were presented and discussed. A differential thermal analyser (DSC-TG) was employed for examination of thermal behavior of MAed powders. Phases of the nanocomposite were confirmed by X-ray diffraction analysis (XRD). The morphologies and microstructure of nanocomposite were investigated by field emission-scanning electron microscopy (FE-SEM) and energy-dispersive X-ray spectroscopy (EDS). Phase composition and distribution were analyzed by electron probe X-ray microanalysis (EPMA). Results showed that TiB2 particles formed in nanoscale were uniformly distributed in alloyed Fe matrix.

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중금속 제거에 우수한 바이오 활성탄 필터의 개발 (Development of Bio-AC Filter for Heavy Metal Adsorption)

  • 김학희;윤경식
    • 유체기계공업학회:학술대회논문집
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    • 유체기계공업학회 2003년도 유체기계 연구개발 발표회 논문집
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    • pp.541-546
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    • 2003
  • Activated carbon was prepared from coffee wastes by chemical activation with $ZnCl_{2}$, NaOH and KOH. The coffee wastes was used as raw material. Preparation process involves the roasting of raw material and carbonization of roasted material followed by chemical activation. N2-BET surface areas of activated coffee char prepared by chemical activation was measured as $1,110{\sim}2,442m^{2}/g$. Removal of copper and chromium in solution by activated carbon was carried out and structural change of pore surface was observed by SEM.

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과망간산염의 산화 과정을 응용한 PET 위 무전해 도금의 은 활성화 공정 (Silver Activation Process Utilizing Permanganate Oxidation for Electroless Copper Plating on PET)

  • 이홍기;허진영;임영생;이건형
    • 한국표면공학회:학술대회논문집
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    • 한국표면공학회 2015년도 춘계학술대회 논문집
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    • pp.181-182
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    • 2015
  • 본 실험에서는 PET 위 무전해 도금을 위한 대안 공정 개발을 목적으로 은(Ag)와 과망간산염($MnO_4{^-}$)를 사용하여 기존에 일반적으로 사용된 Sn/Pd의 Sensitization과 Activation process를 대체하는 기술을 연구했다. Palladium(Pd)의 경우 공정비용에서 높은 부분을 차지하기 때문에 이를 대신하여 Ag를 사용했으며, PET 표면의 전처리를 위해 Ultra Violet과 과망간 산염을 이용하여 표면의 친수성을 높였다. 과망간산염을 사용하여 표면을 전처리하는 과정에서 이산화망간($MnO_2$)과 알코올 작용기가 생성되는데 Ag activation 단계에서 촉매 생성에 중간 매개체 역할을 하는 것으로 사료된다. 이와 같은 결론을 도출 하기 위해서 표면 위 Ag의 화학적 구조 및 상 분석을 위해 XPS와 TEM이 사용되었으며 표면에서 Ag는 Ag-O와 같은 Silver oxide의 형태와 Ag-Mn-O와 같은 Compound로 무전해 도금을 위한 촉매 역할 하는 것으로 판단된다.

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딥러닝 알고리즘 기반 탄산화 진행 예측에서 활성화 함수 적용에 관한 기초적 연구 (A Fundamental Study on the Effect of Activation Function in Predicting Carbonation Progress Using Deep Learning Algorithm)

  • 정도현;이한승
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2019년도 추계 학술논문 발표대회
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    • pp.60-61
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    • 2019
  • Concrete carbonation is one of the factors that reduce the durability of concrete. In modern times, due to industrialization, the carbon dioxide concentration in the atmosphere is increasing, and the impact of carbonation is increasing. So, it is important to understand the carbonation resistance according to the concrete compounding to secure the concrete durability life. In this study, we want to predict the concrete carbonation velocity coefficient, which is an indicator of the carbonation resistance of concrete, through the deep learning algorithm, and to find the activation function suitable for the prediction of carbonation rate coefficient as a process to determine the learning accuracy through the deep learning algorithm. In the scope of this study, using the ReLU function showed better accuracy than using other activation functions.

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