• Journal of Electrical Engineering and Technology
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• 제6권2호
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• pp.263-269
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• 2011

In this study, the compositions for the microwave dielectric materials were investigated to obtain the improved dielectric properties, the high temperature stability, and the sintering temperature of less than $900^{\circ}C$, which was necessary for cofiring with the internal conductor of silver. In addition, the dielectric sheets were prepared by the tape casting technique, after which the sheets were laminated and sintered. In this process, the optimum ratio of powder and binder, laminating pressure, temperature, and possibility for cofiring with the internal conductor were studied. Finally, multilayer chip treplexer filter for the 800-2,000 MHz range were fabricated, and the frequency characteristics of the triplexer filter were investigated. When the $0.6TiTe_3O_8-0.4MgTiO_3+3wt%SnO+7wt%H_3BO_3$ ceramics were sintered at $820^{\circ}C$ for 0.3 hours, the microwave dielectric properties of the dielectric constant of 29.91, quality factor of 33,000 GHz, and temperature coefficient of resonant frequency of -2.76 ppm/$^{\circ}C$ were obtained. Using the Advanced Design System (ADS) and High Frequency Structure Simulator (HFSS), the multilayer chip triplexer filter acting at the range of 800-2,000 MHz were simulated and manufactured. The manufactured triplexer filter had the excellent frequency properties in the CDAM800, GPS and PCS frequency regions, respectively.

• The Korean Journal of Physiology and Pharmacology
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• 제5권2호
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• pp.189-197
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• 2001

To investigate propofol's effects on ionic currents induced by ${\gamma}-aminobutyric$ acid (GABA) and glycine as well as on those produced by the nicotinic acetylcholine- and glutamate-responsive channels, rat dorsal raphe neurons were acutely dissociated and the nystatin-perforated patch-clamp technique under voltage-clamp conditions was used to observe their responses to the administration of propofol. Propofol evoked ion currents in a dose-dependent manner, and propofol $(10^{-4}\;M)$ was used to elicit ion currents through the activation of $GABA_A,$ glycine, nicotinic acetylcholine and glutamate receptors. Propofol at a clinically relevant concentration $(10^{-5}\;M)$ potentiated $GABA_A-,$ glycine- and NMDA receptor-mediated currents. The potentiating action of propofol on $GABA_A-,$ glycine- and NMDA receptor-mediated responses involved neither opioid receptors nor G-proteins. Apparently, propofol modulates inhibitory and excitatory neurotransmitter-activated ion channels either by acting directly on the receptors or by potentiating the effects of the neurotransmitters, and this modulation appears to be responsible for the majority of the anaesthetic and/or adverse effects.

• 해양환경안전학회지
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• 제21권2호
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• pp.200-206
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• 2015

2차원 수중날개의 뒷날에 회전자를 부착한 고양력 발생장치의 성능을 파악하고, 실용화가능성을 살펴보기 위하여 NACA0020형상을 이용하여 모형을 제작하였고 캐비테이션 터널에서 실험을 수행하였다. 양력, 항력, 모멘트의 세 방향의 힘을 계측할 수 있는 가는 막대 형상의 로드셀을 부착하여 유체력을 계측하였으며, 뒷날에 부착된 회전자는 터널 외부에 설치된 DC 서보모터로 회전속도를 제어하였다. 다양한 편향각 조건과 회전자의 회전속도에 따른 체계적인 실험을 통하여 회전자의 효과를 확인하였다. 회전자의 회전속도에 의해 순환제어가 수월하게 조절 가능하다는 점을 실험을 통하여 검증하였으며 회전자의 회전속도에 따라 2배 이상의 양력이 발생함을 확인하였다. 따라서 제안한 양력 장치는 양력조절이 가능한 고양력 발생장치로 충분히 활용할 수 있음을 확인하였다.

• 한국터널지하공간학회 논문집
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• 제21권6호
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• pp.875-885
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• 2019

본 논문은 쉴드 터널의 신뢰성 기반 설계시에 세그먼트 라이닝에 작용하는 전체 하중에 대한 변동계수와 토압에 대한 변동계수를 제시하였다. 이를 위해 국내 도심지 구간에 해당하는 지반 조사 자료를 분석하여 풍화토 및 풍화암에 대한 통계적 특성치를 산정하였으며, MCS기법을 활용하여 이 값들을 Terzaghi 이론식에 적용하여 변동계수를 산정할 수 있었다. 그 결과, 풍화토및 풍화암에 대한 이완하중의 변동계수는 0.08~0.14의 범위로 나타났고, 작용하는 전체 하중에 대한 변동계수는 LC1 = 0.38, LC2 = 0.33, LC3 = 0.37이 적절한 것으로 나타났다. 제시된 변동계수는 쉴드 터널의 세그먼트에 대한 신뢰성 기반 설계시 활용이 가능할 것으로 판단된다.

• Journal of Chest Surgery
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• 제24권3호
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• pp.229-244
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• 1991

A bioassay technique and organ bath study were performed to analyze the effects of extracellular $Ca^{2+}$ and $Ca^{2+}$-antagonists on endothelium-derived relaxing factor[s][EDRF] released from the endothelial cells of rabbit aorta. Transverse strips with intact endothelium or damaged endothelium were used for the mechanical contraction experiment using organ bath. Long segment including thoracic and abdominal aorta with endothelium [EDRF donor aorta] was perfused with Tyrode solution which was aerated with 95% $O_2-5%$ $CO_2$ mixed gas and kept at 35oC. The perfusate was bioassayed with a transverse strip of thoracic aorta with damaged endothelium. The test strip was contracted with nor-epinephrine and acetylcholine was used to stimulate the release of EDRF from endothelial cells. The results obtained were as follows; 1] The endothelium-dependent relaxation[EDR] induced by acetylcholine was biphasic; an initial rapid relaxation followed by a slow relaxation. 2] EDR induced by acetylcholine was reduced gradually with the decrease in the concentration of extracellular $Ca^{2+}$. The effect of extracellular $Ca^{2+}$ on EDR was more prominent in the late slow relaxation phase. 3] EDR to acetylcholine was not altered by acute exposure to organic $Ca^{2+}$-antagonists. Pretreatment with verapamil to the EDRF donor aortic segment did not alter the magnitude of EDR. 4] Among the inorganic $Ca^{2+}$-antagonists $Mn^{2+}$ and $Cd^{2+}$ did not inhibit EDR, whereas $Co^{2+}$ and $La^{3+}$ inhibited EDR. 5] The inhibitory response of $Co^{2+}$ to EDR developed when infused directly on the test strip. That of $La^{3+}$, however, was evoked when added to solution perfusing the donor aortic segment. The above results suggest that $Ca^{2+}$-antagonists do not affect EDR and the inhibitory effect of $Ca^{2+}$ results from influencing the action of EDRF on vascular smooth muscle, whereas that of $La^{3+}$ results from its action on the release of EDRF from endothelial cells.

• Interaction and multiscale mechanics
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• 제2권2호
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• pp.177-187
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• 2009

Machine or structural members subjected to fatigue loading will have a crack initiated during early part of their life. Therefore analysis of members with cracks and other discontinuities is very important. Finite element method has enjoyed widespread use in engineering, but it is not convenient for crack problems as the region very close to crack tip is to be discretized with very fine mesh. However, as the body force method (BFM), requires only the boundary of the discontinuity (crack or hole) to be discretized it is easy versatile technique to analyze such problems. In the present work fundamental solution for concentrated load x + iy acting in the semi-infinite plate at an arbitrary point $z_0=x_0+iy_0$ is considered. These fundamental solutions are in complex form ${\phi}(z)$ and ${\psi}(z)$ (England 1971). These potentials are known as Melan potentials (Ramakrishna 1994). A crack in the semi-infinite plate as shown in Fig. 1 is considered. This crack is divided into number of divisions. By applying pair of body forces on a division, the resultant forces on the remaining 'N'divisions are to be found for which ${\phi}_1(z)$ and ${\psi}_1(z)$ are derived. Body force method is applied to calculate stress intensity factor for crack in semi-infinite plate. Also for the case of crack emanating from circular hole in semi-infinite plate radial stress, hoop stress and shear stress are calculated around the hole and crack. Convergent results are obtained by body force method. These results are compared with FEM results.

• 한국지반공학회논문집
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• 제27권3호
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• pp.55-61
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• 2011

일반적으로 하천제방 배수통문은 다양한 원인에 의하여 붕괴가 발생하며, 특히 연약지반 상에 말뚝기초를 이용하여 설치된 경우 1) 주변 지반(외부토체)/말뚝기초 처리된 암거 상단(내부토체)의 상대적 침하 차에 의한 배수통문 암거 측벽부의 다짐도 약화, 2) 하이드로릭 플랙처링에 의한 홍수 시 침투수압의 지속적 반복에 의한 측벽부 교란 등에 의해 붕괴가 발생한다. 특히 측벽부는 시공여건상 다짐장비의 접근이 어려운 다짐 취약부이고, 이질재료에 의한 마찰력 감소로 전단저항력이 일반 흙의 전단강도에 비해 1/3 이상 감소하여 발현된다. 이에 본 연구에서는 주변 지반에 인위적인 변형을 발생시키는 방법으로 침하를 모사한 실내 모형실험을 통하여 연약지반 상 말뚝 기초된 배수통문 암거의 상대적 침하에 따른 외부토체/내부토체 발현 메카니즘과 저판확폭에 따른 배수통문 암거 측벽부 다짐도 향상 효과를 비교 분석함으로써 배수통문 저판 확폭을 통한 주변지반 공동 확장 억제기법을 제시하였다.

• 한국지반환경공학회 논문집
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• 제11권10호
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• pp.25-31
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• 2010

사면보강 및 기초공법으로 앵커공법, 소일네일공법 및 소구경 말뚝공법 등이 널리 사용되고 있다. 이들 공법은 공통적으로 보강재를 설치한 후 그라우팅을 실시한다. 국내의 경우 중력식과 가압식 그라우팅 방식을 주로 사용하고 있다. 반면, 재주입 그라우팅 방식은 시공장비와 적용 실적의 부족 및 보강효과 검증이 어려워 널리 적용되지 못하고 있는 실정이다. 재주입 그라우팅은 포스트 그라우팅 방식의 일종으로 그라우트체 주면의 응력을 증대시키고 정착장에 불규칙한 표면을 조성함으로써 그라우트와 지반의 저항을 크게 할 수 있다. 이에 본 연구에서는 그라우팅 주입 방식에 따른 보강효과를 비교하고, 재주입 그라우팅 방식으로 시공된 보강재의 인발특성을 평가하기 위하여 현장실험을 실시하였다. 실험결과 재주입 그라우팅에 따른 인발력 증대를 확인할 수 있었다.

• International Journal of Oral Biology
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• 제33권4호
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• pp.217-221
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• 2008

Bicuculline is one of the most commonly used $GABA_A$ receptor antagonists in electrophysiological research. Because of its poor water solubility, bicuculline quaternary ammonium salts such as bicuculline methiodide (BMI) and bicuculline methbromide are preferred. However, a number of studies have shown that BMI has non-$GABA_A$ receptor-mediated effects. The substantia gelatinosa (SG) of the trigeminal subnucleus caudalis (Vc) is implicated in the processing of nociceptive signaling. In this study, we investigated whether BMI has non-GABA receptor-mediated activity in Vc SG neurons using a whole cell patch clamp technique. SG neurons were depolarized by application of BMI ($20{\mu}M$) using a high $Cl^-$ pipette solution. GABA ($30-100{\mu}M$) also induced membrane depolarization of SG neuron. Although BMI is known to be a $GABA_A$ receptor antagonist, GABA-induced membrane depolarization was enhanced by co-application with BMI. However, free base bicuculline (fBIC) and picrotoxin (PTX), a $GABA_A$ and $GABA_C$ receptor antagonist, blocked the GABA-induced response. Furthermore, BMI-induced membrane depolarization persisted in the presence of PTX or an antagonist cocktail consisting of tetrodotoxin ($Na^+$ channel blocker), AP-5 (NMDA receptor antagonist), CNQX (non-NMDA receptor antagonist), and strychnine (glycine receptor antagonist). Thus BMI induces membrane depolarization by directly acting on postsynaptic Vc SG neurons in a manner which is independent of $GABA_A$ receptors. These results suggest that other unknown mechanisms may be involved in BMI-induced membrane depolarization.

• 복식
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• 제59권7호
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• pp.86-99
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• 2009

The audience of the performing arts enacted on the stage appreciate acting of the characters in a play to understand its plot, identify with the characters, and comprehend the message and subject matters of the play. Stage make-up in particular should assist audience in comprehending the story without overpowering or distracting the script. Stage make-up is a crucial means to visualize occupation, class, personality, and age of the characters. Thus it is an essential means in producing a high quality performance. The aim of the study is to examine character-emphasis make-up for a play by reviewing theories on the concepts and methods of the stage make-up. The methodology of the study was to analyze character make-up of the adopted play The Madwoman of Chaillot (La Folle de Chaillot) translated from the original French, as a case study. The technique and features of the character make-up of the play were examined, and functions of each factor of the character make-up depending on a role were also examined. The results of the study are as follows. The stage make-up for creating and expressing a distinctive personality of the characters in a play must integrate environmental factors external to a performance such as lighting and scale of a venue. Moreover the stage make-up must adopt and reconstruct internal factors of the play such as interpretation of the original work, subject matters, interpretation of the script, character analysis based on the discussion with a director, and design setting.