• 한국실내디자인학회논문집
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• 제20권1호
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• pp.138-145
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• 2011

This study analyzed the time to understand the space and the contents of information to be memorized in the indoor space. Understanding the space and examining the memory will not only provide the basic data on which visual activities occur in user's perceiving the designed space but also expand the activity range of interior designer. The summary of the study results is as follows: First, with respect to gender difference, the results showed that males grasped the space in a relatively shorter time. Females showed more concentrated distribution range than males. Second, as for the proper time by accumulative sum across time, the results showed that it increased continuously until V time zone(120~150 seconds), it decreased rapidly after the V zone, which indicated that the proper gazing time for the indoor space as the target of this study is less than 150 seconds(effective gazing time). Third, in terms of efficiency of information acquisition, the results suggested that "60~90 seconds" are the effective time for acquiring the greatest amount of information. Fourth, regarding the information acquisition method, males were approximately 4.1%~0.1% lower in the evaluation through phrase and image. The evaluation of subjects through phrase than image was connected to more accurate information acquisition.

• 한국경제지리학회지
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• 제12권1호
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• pp.56-66
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• 2009

정보의 양이 급격히 늘어나고, 유비쿼터스 도시 환경이 출현하고 있다. 이에 따라, 소비자가 어떤 유형의 정보를 어떤 정보 전달 매체를 통해 이용하는가 하는 문제는 공공 및 상업적 교통정보 서비스 제공자에게 공통으로 중요한 문제가 되어 있다. 본 연구는 최근 수도권에서 수집한 대중교통 이용자의 대중교통 정보습득 및 정보전달 매체선택에 관한 자료분석의 첫 번째 결과물을 보고한다. 연구는 정보의 습득과 정보매체의 선택은 정보 이용의 의사결정 상황에 크게 의존한다는 가정에 기초한다. 이에 따라 본 연구는 상황에 따라 가변적인 의사결정의 원리를 탐구하는 데 적합한 decision table 및 CHAID 분석을 응용하여 정보 습득과 정보매체 선택의 동질적 segment를 확인한다. 분석 결과, 정보 습득 및 정보매체 선택에 정보 이용 당시의 이용 교통수단 및 수행 활동 등 상황변수가 중요한 역할을 하고 있음을 알 수 있었다. 이에 더해 정보 습득에는 정보 이용 당시의 시각 역시 중요하며, 정보매체 선택에는 이용 정보 내용이 추가적으로 중요한 상황 변수임을 알 수 있었다. 연구 결과는 동적 market segmentation에 관한 중요한 시사점을 제공하고 있다.

• 동의생리병리학회지
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• 제16권6호
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• pp.1151-1156
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• 2002

This research was done to make the effective prescription and cope with various senile dementia. Sprague-Dawley rats were injured by ibotenic acid to make a damage on learning and memory functions of model rats. At first acquisition test and retention rest were done in the Morris water maze. And to evaluate the effects of the sample drug(GSD) on choline acetyltranferase and acetylcholine esterase, immunoreactive measurement and enzymatic activity measuring were carried out. The ibotenic acid were injected to hippocampus CA1 and CA3 area. Conclusion : GSD improved the learning ability in the acquisition test and memory function in the retention test significantly. And GSD increased the level of ChAT which is synthesizing acetylcholine in CA1 area, and at the same time it increased the level of AChE which is resolving acetylcholine. These results show that GSD improved the cholinergic catabolism and anabolism, and the increment of metabolic activity of cholinergic system. In other words, it contributes to the recovery of damaged learning and memory function by ibotenic acid. So it can be concluded that GSD will be helpful to cholinergic brain damage induced by primary or senile reduction of acetylcholine secretive activity.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 ITC-CSCC -2
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• pp.1165-1168
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• 2002

Knowledge acquisition is the process that extracts the required knowledge from available sources, such as experts, textbooks and databases, for incorporation into a knowledge-based system. Knowledge acquisition is described as the first step in building expert systems and a major bottleneck in the efficient development and application of effective knowledge based expert systems. One cause of the problem is that the process of human reasoning we need to understand for knowledge-based system development is not available for direct observation. Moreover, the expertise of interest is typically not reportable due to the compilation of knowledge which results from extensive practice in a domain of problem solving activity. This is also a problem of modeling knowledge, which has been described as not a problem of accessing and translating what is known, but the familiar scientific and engineering problem of formalizing models for the first time. And this formalization process is especially difficult for knowledge engineers who are often faced with the difficult task of creating a knowledge model of a domain unfamiliar to them. In this paper, we propose an automated knowledge acquisition tool which is based on an implementation of the Inferential Modeling Technique. The Inferential Modeling Technique is derived from the Inferential Model which is a domain-independent categorization of knowledge types and inferences ［Chan 1992］. The model can serve as a template of the types of knowledge in a knowledge model of any domain.

• 대한방사선기술학회지:방사선기술과학
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• 제44권6호
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• pp.655-661
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• 2021

Positron emission tomography (PET) images is affected by acquisition time, short acquisition times results in low gamma counts leading to degradation of image quality by statistical noise. Noise2Void(N2V) is self supervised denoising model that is convolutional neural network (CNN) based deep learning. The purpose of this study is to evaluate denoising performance of N2V for PET image with a short acquisition time. The phantom was scanned as a list mode for 10 min using Biograph mCT40 of PET/CT (Siemens Healthcare, Erlangen, Germany). We compared PET images using NEMA image-quality phantom for standard acquisition time (10 min), short acquisition time (2min) and simulated PET image (S2 min). To evaluate performance of N2V, the peak signal to noise ratio (PSNR), normalized root mean square error (NRMSE), structural similarity index (SSIM) and radio-activity recovery coefficient (RC) were used. The PSNR, NRMSE and SSIM for 2 min and S2 min PET images compared to 10min PET image were 30.983, 33.936, 9.954, 7.609 and 0.916, 0.934 respectively. The RC for spheres with S2 min PET image also met European Association of Nuclear Medicine Research Ltd. (EARL) FDG PET accreditation program. We confirmed generated S2 min PET image from N2V deep learning showed improvement results compared to 2 min PET image and The PET images on visual analysis were also comparable between 10 min and S2 min PET images. In conclusion, noisy PET image by means of short acquisition time using N2V denoising network model can be improved image quality without underestimation of radioactivity.

• Investigative Magnetic Resonance Imaging
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• 제25권1호
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• pp.1-9
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• 2021

The aim of this study was to provide a new assessment of rotator cuff muscle activity. Eight male subjects (24.7 ± 3.2 years old,171.2 ± 9.8 cm tall, and weighing 63.8 ± 11.9 kg) performed the study exercises. The subjects performed 10 sets of the exercise while fixing the elbow at 90 degrees flexure and lying supine on a bed. One exercise set consisted of the subject performing external shoulder rotation 50 times using training equipment. Two imaging protocols were employed: (a) true fast imaging with steady precession (TrueFISP) at an acquisition time of 12 seconds and (b) multi-shot spin-echo echo-planar imaging (MSSE-EPI) at an acquisition time of 30 seconds for one echo. The main method of assessing rotator cuff muscle activity was functional T2 mapping using ultrafast imaging (fast-acquired muscle functional MRI [fast-mfMRI]). Fast-mfMRI enabled real-time imaging for the identification and evaluation of the degree of muscle activity induced by the exercise. Regions of interest were set at several places in the musculus subscapularis (sub), musculus supraspinatus (sup), musculus teres minor (ter), and deltoid muscle (del). We used the MR signal of the images and transverse relaxation time (T2) for comparison. Most of the TrueFISP signal was not changed by exercise and there was no significant difference from the resting values. Only the T2 in the musculus teres minor was increased after one set and the change were seen on the T2 images. Additionally, except for those after one and two sets, the changes in T2 were significant compared to those at rest (P < 0.01). We also demonstrated identify and visualize the extent to which muscles involved in muscle activity by exercise. In addition, we showed that muscle activity in a region such as a shoulder, which is susceptible to B0 inhomogeneity, could be easily detected using this technique.

• 핵의학기술
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• 제17권2호
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• pp.72-77
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• 2013

Purpose: Whole-body PET using radiopharmaceutical is one of the imaging study methods for physiological changes of body. High specificity of the PET-CT examination is used to detect an early stages of cancer and metastatic cancer by imaging a physiological changes. During the imaging process, PET image has been characterized by a relatively low image quality due to its low sensitivity and the acquisition of random and scatter coincidences as well as patients figure. Therefore, the image quality as the changes of the acquisition times of patient weight was evaluated in this study. Materials and Methods: Thirty patients who presented to our hospital were enrolled. They were divided to normal, overweight, and obese group using BMI index, respectively. The patients with a liver disease and diabetes were excluded. $^{18}F-FDG$ was administered to the patients as 5.2 MBq per kg. After an hour from an injection, image acquisition was obtained as List mode in a part of liver in 1 bed. SNR (signal-to-noise ratio) of each groups acquisition times were confirmed from the calculated radiation counts and random fractions. The statistical significance of three groups was confirmed through one-way ANOVA test. On the basis of the counts of 2 minutes on normal group, the SNR of overweight group and obese group were compared. Results: The SNR were increased with loger aquisition time in 3 groups. In the condition of same acquisition time, the SNR had a statistical significance (P<0.05). The SNR were decreased to the normal, overweight, and obese, respectively. Liver activity had no significance difference on each group and RF had the significance differences (P<0.05). On the basis of the counts of 2 minutes on normal group, there were no statistical significance in a three minute acquisitions of overweight group and two minute acquisitions of obese group (P=0.150). Conclusion: In this study, the administrated amount of radiation dose did not adjust as the change of the patients weight. Increasing the acquisition time when the administration of the same amount of dose was able to get a good result of SNR. When the Based 2 minute on normal group, if overweight and obese case the increased acquisition time of 3 minute was able to obtain a similar SNR. On the basis of the normal group, the acquisition times of overweight and obese group were increased to 3 minutes per bed and the SNR were similar to the normal group.

• Journal of Yeungnam Medical Science
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• 제18권1호
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• pp.39-50
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• 2001

본 연구는 여러 가지 질병의 원인을 규명하는데 있어서 자율신경계 역할의 중요성을 인식하여 심전도 및 호흡신호의 변이를 이용하여 자율신경계를 감시할 수 있는 시스템을 개발하였다. 본 연구에서 제작된 증폭기에서는 트랜스를 사용하여 교류전원으로부터 환자를 격리시키고, 30 KHz의 고주파를 이용하여 임피던스법에 의한 호흡신호를 심전도와 동시에 처리할 수 있도록 하였으며, 아울러 서로의 채널에 대한 혼신의 영향을 최소화하도록 회로를 설계하였다. 시뮬레이터에 의한 테스트 결과에서 입력 조건에 따라 증폭기의 출력에 나타나는 시간 간격이 일치하게 나타나는 것을 확인하였다. 또 실제 서로 다른 조건을 가진 세 부류의 임상 환자의 심전도에서 R-R interval 및 호흡신호를 측정하여 추출할 수 있었다. 기존에는 주로 생체 신호 파라미터를 각각 측정하여 그 결과를 추출하였으나 본 연구에서는 R-R interval과 respiration의 파라미터를 통합하여 데이터를 수집, 처리함으로써 환자로부터 얻은 데이터를 임상 응용에 보다 효과적으로 적용할 수 있게 되었다. 따라서 향후 개발된 시스템의 보완을 통해 환자에 직접 적용하여 자율신경계 장애 환자에 대한 감시장치로 활용하고자 한다.

• 정보관리학회지
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• 제19권1호
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• pp.71-88
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• 2002

본 연구는 상호대차활성화에 따른 이·공계열 외국학술지의 이용빈도를 조사해보고, 외국학술지 분담구독의 모델을 제시하는데 그 목적이 있다. 본 이용연구는 2000년도 E대학도서관의 459종의 구독학술지와 144종의 분담구독 학술지를 포함한 총 603종을 평가대상으로 하여 관내 이용통계와 상호대차통계를 분석한 것이다. 본 연구결과 439종의 학술지가 1회 이상 이용되었으며. 164종의 불용학술지가 조사되었다. 또한 E대학 이용자의 이용빈도와 JCR의 주제 분야별 총 인용빈도 상위 학술지간에는 상관성이 있는 것으로 나타났다. 다양한 이용분석을 통하여 본 연구는 효과적인 학술지 관리방안을 제시하였다.

• 대한한의학회지
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• 제28권3호통권71호
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• pp.183-196
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• 2007

Objective : This study was conducted in order to find the effects of Gammaekdaejo-tang (Ganmaidazao-tang, GDT) by subjecting rats to immobilization stress, thereby inducing depression, anxiety and acquisition-retention defects. Method : Rats treated with normal saline, GDT 200mg/kg and GDT 400mg/kg were subjected to stress by immobilization. Afterwards, behavior changes were observed by elevated plus maze test, acquisition test and retention test in the Morris water maze. The results were obtained by immunohistochemically measuring stress hormone (corticosteroid) levels in the blood. Results and Conclusions : 1. The open arm test in the elevated plus maze showed that compared with the normal group, the time spent decreased in the control group and increased in the GDT 400mg/kg group. 2. The locomotor activity test in the elevated plus maze revealed that the control group showed significant activity decrease compared with the normal group but significant increase in the GDT 400mg/kg group. 3. The acquisition test in the Morris water maze showed that the acquisitive ability of the control group significantly deteriorated on the 3rd and 4th day compared with the normal group, but improved significantly in the GDT 200mg/kg and GDT 400mg/kg groups. 4. The retention test on the 7th day in the Morris water maze revealed that the retentive ability of the control group significantly deteriorated compared with the normal group, but the retentive ability of the GDT 400mg/kg group significantly improved. 5. The blood levels of corticosteroid in the control group increased significantly compared with the normal group but the levels of corticosterone in the blood of the GDT 400mg/kg group significantly decreased.