• Title/Summary/Keyword: Acid resistance

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Transferable R plasmid of Edwardsiella tarda isolated from diseased flounders, Paralichithys olivaceus (넙치에서 분리된 Edwardsiella tarda의 약제내성 전달성 R plasmid)

  • Kim, Eun-Heui
    • Journal of fish pathology
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    • v.12 no.2
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    • pp.115-121
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    • 1999
  • MIC test of 16 chemotherapeutic agents was performed on 24 isolates of Edwardsiella tarda collected from flounders. They revealed resistance against combinations of ampicillin, amoxicillin, erythromycin, flumequine, doxycycline(DOXY), nalidixic acid, novobiocin, oxolinic acid, oxytetracycline(OTC), thiamphenicol(TP) and sulfonamide. Two strains carried transferable R plasmid encoding Otc Kanamycin Tp and Otc chloramphenicol Doxy Tetracycline Tp, respectively. The R plasmids were not similar each other on the basis of their digestion pattern of restriction endonuclease, suggesting distribution of different transferable R plasmid among E. tarda from flounders.

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Antibiotic Resistance Among Salmonella spp. Isolated from Feces of Patients with Acute Diarrhea in Gwangju Area, Korea, during 2000-2009 (2000년-2009년 광주 광역시 지역의 급성설사환자의 분변에서 분리한 살모넬라 균주에서의 항생제 내성률 조사)

  • Kim, Tae Sun;Kim, Min Ji;Kim, Sun Hee;Seo, Jin-Jong;Kee, Hye Young;Chung, Jae Keun;Kim, Eun Sun;Moon, Yong Woon;Ha, Dong Ryong;Kim, Min Kyeong;Lim, Suk Kyung;Nam, Hyang-Mi
    • Korean Journal of Microbiology
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    • v.49 no.2
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    • pp.118-125
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    • 2013
  • Antibiotic susceptibility was examined for 596 Salmonella isolates from patients with acute gastroenteritis during 2000-2009 in Gwangju area in South Korea. Of 16 antibiotics tested, ampicillin resistance (43%) was the most commonly observed resistance among the 596 Salmonella sp. isolates, followed by tetracycline (35.9%), nalidixic acid (31.5%), and chloramphenicol (26.2%). Antibiotic resistance varied among serotypes: The highest resistance of S. Enteritidis and S. Typhimurium was to ampicillin (51.1%) and tetracycline (77.9%), respectively. A total of 89 resistance patterns were observed, and 26% (155/596) of Salmonella isolates were susceptible to all antibiotics tested in this study. About 21% (127/596) and 15% (87/596) of the isolates were resistant to one and two antibiotics, respectively. The rest of Salmonella isolates (227/596, 38%) were resistant to three or more antibiotic agents. The highest multi-drug resistance (MDR) was observed in serotype S. Paratyphi B (76.5%), followed by S. Typhimurium (58.2%), and S. Enteritidis (40.2%). The most common resistance pattern of MDR isolates was ampicillin-chloramphenicol-nalidixic acid-ticarcillin (36/227, 15.8%), most of which (35/36, 97.2%) were S. Enteritidis.

Evaluation of Two Species of Soft Wood Decay Resistance for Heat-Treated Wood Using the Catalyst (H2SO4)

  • Won, Kyung-Rok;Hong, Nam-Euy;Jung, Su-Young;Kim, Byung-Ro;Byeon, Hee-Seop
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.2
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    • pp.195-201
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    • 2017
  • This study was conducted to evaluate the resistance of heat-treated wood using the catalyst to decay caused by fungi for sapwood and heartwood of two tree species, Korean red pine (Pinus densiflora) and Japanese larch (Larix kaempferi), respectively. Wood samples were immersed for 10 min in sulfuric acid (7.5%) and then heat-treated at $130^{\circ}C$ for 90 min. Fomitopsis palustris, a brown-rot fungus, was used to examine the decay resistance of Korean red pine and Japanese larch wood. Weight and density of wood from the all conditions increased after heat treatment using the catalyst. Weight loss after decay resistance test was also dropped with a heat treatment. The lowest weight loss indicated at heat-treated heartwood of Japanese larch. Heat treatment using the catalyst effectively increased the resistance of wood to decay caused by fungi.

Association between Dietary Acid Load and Insulin Resistance: Tehran Lipid and Glucose Study

  • Moghadam, Sajjad Khalili;Bahadoran, Zahra;Mirmiran, Parvin;Tohidi, Maryam;Azizi, Fereidoun
    • Preventive Nutrition and Food Science
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    • v.21 no.2
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    • pp.104-109
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    • 2016
  • In the current study, we investigated the longitudinal association between dietary acid load and the risk of insulin resistance (IR) in the Tehranian adult population. This longitudinal study was conducted on 925 participants, aged 22~80 years old, in the framework of the third (2006~2008) and fourth (2009~2011) phases of the Tehran Lipid and Glucose Study. At baseline, the dietary intake of subjects was assessed using a validated semi-quantitative food frequency questionnaire, and the potential renal acid load (PRAL) and net endogenous acid production (NEAP) scores were calculated at baseline. Fasting serum insulin and glucose were measured at baseline and again after a 3-year of follow-up; IR was defined according to optimal cut-off values. Multiple logistic regression models were used to estimate the risk of IR according to the PRAL and NEAP quartile categories. Mean age and body mass index of the participants were 40.3 years old of $26.4kg/m^2$, respectively. Mean PRAL and NEAP scores were -11.2 and 35.6 mEq/d, respectively. After adjustment for potential confounders, compared to the lowest quartile of PRAL and NEAP, the highest quartile was accompanied with increased risk of IR [odds ratio (OR)=2.81, 95% confidence interval (CI)=1.32~5.97 and OR=2.18, 95% CI=1.03~4.61, respectively]. Our findings suggest that higher acidic dietary acid-base load, defined by higher PRAL and NEAP scores, may be a risk factor for the development of IR and related metabolic disorders.

Corrosion Characteristics of Corrosion-Resistant Metal with Different Composition Ratios of Acetic Acid and Acetonitrile at High Temperature and Pressure (고온 및 고압조건에서 아세트산과 아세토나이트릴의 성분비에 따른 부식저항성 금속의 부식특성)

  • Hyun-Kyu Hwang;Dong-Ho Shin;Seung-Jun Lee;Seong-Jong Kim
    • Corrosion Science and Technology
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    • v.23 no.2
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    • pp.154-165
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    • 2024
  • Acetic acid and acetonitrile produced in the chemical process of petrochemical plants are used at high temperatures and pressures. They are exposed to harsh corrosive environments. The present investigation aimed to evaluate corrosion characteristics of metals with excellent corrosion resistance by performing immersion and electrochemical experiments with different composition ratios of acetic acid and acetonitrile in a high-temperature and high-pressure environment. Results of immersion experiment revealed that as acetic acid concentration increased, surface damage and corrosion also increased. In immersion experiments under all conditions, super austenitic stainless steel (UNS N08367) had the best corrosion resistance among various metals. The maximum damage depth under the most severe immersion conditions was observed to be 4.19 ㎛, which was approximately 25.25 ㎛ smaller than that of highly damaged stainless steel (UNS S31804). As a result of electrochemical experiments, electrochemical characteristics of various metals presented some differences with different composition ratios of acetic acid and acetonitrile. However, super austenitic stainless steel (UNS N08367) had the best corrosion resistance at a high pressure condition with a high concentration of acetic acid.

Study on the Development of SiC-containing Technical Porecelain Body (SiC 질 공업용 도자기 개발에 관한 연구)

  • 박정현;배원태;권오훈
    • Journal of the Korean Ceramic Society
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    • v.19 no.1
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    • pp.5-12
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    • 1982
  • SiC-containing by-product from the surface abrasion process of porcelain cores is used as a starting material to develop the SiC-containing technical porcelain bodies. To prevent the bloating phenomenon of by-product specimen at firing temperature, it is acid treated. In order to enhance the workability and to lower the firing temperature of bodies, clay is added. Body containing 25% clay and 75% by-product fired at 135$0^{\circ}C$ showes extremely high thermal shock resistance and acid resistance.

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Nucleotide Sequences of Rep and CAT Proteins encoded by Chloramphenicol-Resistance Plasmid pKH7 (클로람페니콜 내성 플라스미드 pKH7의 Rep 단백질과 CAT 단백질의 염기서열 분석)

  • 윤성준;이대운;김우구;신철교;임성환;문경호
    • YAKHAK HOEJI
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    • v.39 no.6
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    • pp.676-680
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    • 1995
  • The nucleotide sequence of Xbal-Mbol fragment of pKH7, a chloramphenicol-resistant($Cm^{r}$) plasmid isolated from multidrug-resistant S. aureus SA2, has been determined. Xbal-Mbol fragment of pKH7 was found to contain two ORFs. One ORF encoded Rap and the other encoded CAT protein. The deduced amino acid sequences of Rep and CAT of pKH7 were compared to those of pUB112 and pC221. Comparisons revealed that there was one amino acid difference in CAT between pKH7 and pUB112. CAT of pKH7 exhibited 98.6% amino acid identity to that of pC221. In case of Rep proteins, a slightly lower homology of 96.4% and 86.7% in amino acid sequences was observed between pKH7 and pUB112 and between pKH7 and pC221, respectively.

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Characteristics of Sulfuric acid corrosion of Recycled PET Polymer Concrete with Different Filler (충전재 변화에 따른 PET 재활용 폴리머 콘크리트의 황산 부식에 관한 특성)

  • Jo Byung Wan;Gu Ja Kap;Park Jong Hwa;Park Seung Kook
    • Proceedings of the Korea Concrete Institute Conference
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    • 2004.11a
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    • pp.719-722
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    • 2004
  • Resins using recycled PET offer the possibility of a lower source cost of materials for making useful polymer concrete products. The purposed of this paper is to form a part of reducing the damage of sulfuric acid, through investigating recycled PET polymer concrete, . immersed at sulfuric acid solution for 84 days. Recycled PET PC is excellent chemical resistance, resulting in the role of unsaturated polyester resin which consists of polymer chain structure accomplishes bond of aggregates and filler strongly. Also, Recycled PET PC, used fly-ash as filler, is stronger resistance of sulfuric acid corrosion than $CaCO_3$, because it is composed of $SiO_2$ and very strong glassy crystal structure. Therefore, Recycled PET PC, used fly-ash as filler, is available under corrosion circumstances like sewer pipe or waste disposal plant.

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Effect of Adding Scoria as Cement Replacement on Durability-Related Properties

  • al-Swaidani, Aref Mohamad;Aliyan, Samira Dib
    • International Journal of Concrete Structures and Materials
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    • v.9 no.2
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    • pp.241-254
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    • 2015
  • A lot of reinforced concrete (RC) structures in Syria went out of service after a few years of construction. This was mainly due to reinforcement corrosion or chemical attack on concrete. The use of blended cements is growing rapidly in the construction industry due to economical, ecological and technical benefits. Syria is relatively rich in scoria. In the study, mortar/concrete specimens were produced with seven types of cement: one plain Portland cement (control) and six blended cements with replacement levels ranging from 10 to 35 %. Rapid chloride penetration test was carried in accordance with ASTM C 1202 after two curing times of 28 and 90 days. The effect on the resistance of concrete against damage caused by corrosion of the embedded steel has been investigated using an accelerated corrosion test by impressing a constant anodic potential. The variation of current with time and time to failure of RC specimens were determined at 28 and 90 days curing. In addition, effects of aggressive acidic environments on mortars were investigated through 100 days of exposure to 5 % $H_2SO_4$, 10 % HCl, 5 % $HNO_3$ and 10 % $CH_3COOH$ solutions. Evaluation of sulfate resistance of mortars was also performed by immersing in 5 % $Na_2SO_4$ solution for 52 weeks. Test results reveal that the resistance to chloride penetration of concrete improves substantially with the increase of replacement level, and the concretes containing scoria based-blended cements, especially CEM II/B-P, exhibited corrosion initiation periods several times longer than the control mix. Further, an increase in scoria addition improves the acid resistance of mortar, especially in the early days of exposure, whereas after a long period of continuous exposure all specimens show the same behavior against the acid attack. According to results of sulfate resistance, CEM II/B-P can be used instead of SRPC in sulfate-bearing environments.

Sulfonylurea Herbicide Resistance Mechanism of Some Acetohydroxy Acid Synthase Mutants and New Designed Herbicides Specific to the Mutants

  • Choe, Mun Myong;Kang, Hun Chol;Kim, In Chul;Li, Hai Su;Wu, Ming Gen;Lee, Im Shik
    • Weed & Turfgrass Science
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    • v.6 no.1
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    • pp.28-31
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    • 2017
  • The mutation rate of proline in the position 197 (Pro197) in acetohydroxy acid synthase (AHAS) is highest among sulfonylurea (SU) herbicide-resistance mutants. Therefore, it is significant to investigate the resistance mechanism for the mutation and to develop the herbicides specific to the mutants. SU herbicide resistance mechanism of the mutants, 197Ser, 197Thr and 197Ala, in AHAS were targeted for designing new SU-herbicide. We did molecular dynamics (MD) simulation for understanding SU herbicide-resistance mechanisms of AHAS mutants and designed new herbicides with docking and MD evaluations. We have found that mutation to 197Ala and 197Ser enlarged the entrance of the active site, while 197Thr contracted. Map of the root mean square derivation (RMSD) and radius gyrations (Rg) revealed the domain indicating the conformations for herbicide resistant. Based on the enlarging-contracting mechanism of active site entrance, we designed new herbicides with substitution at the heterocyclic moiety of a SU herbicide for the complementary binding to the changed active site entrances of mutants, and designed new herbicides. We confirmed that our screened new herbicides bonded to both AHAS wild type and mutants with higher affinity, showing more stable binding conformation than the existing herbicides.