• Title/Summary/Keyword: Acetophenones (ketone)

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Efficient Synthesis of β-Acetamido Ketones by Silver(I) Triflate-Catalyzed Multicomponent Reactions

  • Pandit, Rameshwar Prasad;Lee, Yong Rok
    • Bulletin of the Korean Chemical Society
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    • v.33 no.11
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    • pp.3559-3564
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    • 2012
  • An efficient one-pot synthesis of ${\beta}$-acetamido ketones was accomplished by AgOTf-catalyzed multicomponent reactions of substituted acetophenones with aromatic aldehydes and acid chloride in acetonitrile in high yields. The methods offer several significant advantages of easy handling, mild reaction conditions, and use of effective and non-toxic catalyst.