• Title/Summary/Keyword: Accuracy Standards

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National Measurement Standard of Electrical Resistance using a Room Temperature Resistance Bridge (실온 저항브리지를 이용한 전기저항 측정의 국가표준 기술)

  • Yu, Kwang-Min;Park, Young-Tae;Kang, Jean-Hong;Kim, Han-Jun;Ihm, G.
    • Proceedings of the KIEE Conference
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    • 2002.07b
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    • pp.669-672
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    • 2002
  • Establishment of the Quantum Hall Resistance(QHR) Standard as national resistance standard using a room temperature DCC resistance bridge is described. A simple method are used to obtain the current dependence and error of 10: 1 ratio of the bridge instead of the method using a cryogenic resistance bridge. Measurement uncertainty of the system is estimated as $0.14{\times}10^{-6}$ and it is confirmed that the QHR standard is agreed well with the QHR of other NMIs using the cryogenic resistance bridge within the uncertainty, More improvement about performance of the QHR device and 10: 1 ratio accuracy is still under progress.

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Mass measuremeant of soilid density standard using weight exchanger (분동교환기를 이용한 고체밀도기준물의 질량측정)

  • 이용재;장경호;오재윤;정상덕
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1659-1662
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    • 2003
  • The mass measurement of solid density standards using weight exchanger is described. KRISS(Korea Research Institute od Standards and Science) has several solid density standards. Their mass have been measured manually only using a mass comparator(Mettler, 1kg - 0.01mg). However, the uncertaity of the manual mass measurement is up to 300 microgarm much more than 32 microgram of advanced NMIS(National Metrology Institutes) for 1 kg silicon sphere which is primary density standards due to an eccentric error and buoyancy correction error. The new system with a weight exchanger is designed and built to improve the measurement accuracy. It comprises a weight exchager, a mass comparator, air density instruments, and application program for automatic measurement. It is evaluated by measuring several elements in an air tight chamber to verify the performance of it.

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Development of a Time Comparison System via GPS Satellites (GPS 위성을 이용한 시각비교 수신기의 개발)

  • Lee, Chang-Bok;Lee, Dong-Doo;Chung, Nak-Sam
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.27 no.2
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    • pp.158-165
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    • 1990
  • We have developed a L1 band (1575.42 MHz), C/A (Coarse/Acquisition) code GPS (Global Positioning System) receiver for precise time comparison and evaluated the performance of the receiver. The GPS measurements have been carried out between cesium clocks onboard the GPS satellites and the master clock of Korea Standards Research Institute (KSRI) using the GPS receiver. An accuracy of time transfer better than 100ns was obtained.

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Development of Maxwell-Wien Bridge System for Extablishment of Inductance Primary Standards (인덕턴스의 국가 표준 확입을 위한 막스웰-윈 브릿지 연구 개발)

  • Lee, Rae-Deok;Do, Jae-Hong;Kim, Chang-Seok
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.20 no.4
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    • pp.36-40
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    • 1983
  • It is very difficult to measure inductance more accurately than 0.1% by the general AC bridges. A Maxwell-Wien bridge system has been developed for establishment and propagation of the national inductance standards. In results of its capability analysis, the accuracy of this bridge system was obtained up to ${\pm}$200 ppm for the present.

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Accuracy Assessment for Measuring Surface Figures of Large Aspheric Mirrors

  • Kim, Young-Soo;Ahn, Ki-Beom;Park, Kwi-Jong;Moon, Il-Kweon;Yang, Ho-Soon
    • Journal of the Optical Society of Korea
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    • v.13 no.2
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    • pp.178-183
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    • 2009
  • At the time that the Keck-I 10m telescope was constructed in 1993, the era of Very Large Telescopes (VLTs) was opened. Now thirteen VLTs are in operation, and the largest of the monolithic mirrors is 8.4 m in diameter. Such monolithic mirrors are mostly aspheric and require high accuracies on the surface figures, reaching up to the diffraction limit. At present, next generation telescopes, Giant telescopes, are being developed. One is the GMT (Giant Magellan Telescope) whose size is 25.4 m in diameter. The primary mirror consists of seven segments figuring elliptical shapes on the surface. The surrounding six segments are off-axis and the edges are steep, as the fast focal ratio is adopted. It means that testing of the mirrors is a challenging task. In this paper, testing methods for the GMT primary mirror are reviewed, and accuracy of measuring devices is assessed. Results and discussions follow.

Statistical Analysis on the Sources of Variance in Proficiency Test of Quantitative Analysis of Medicines (의약품 함량분석 정도관리에서의 변이 요인에 대한 통계분석)

  • Cho, Jung-Hwan
    • Journal of Pharmaceutical Investigation
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    • v.37 no.1
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    • pp.27-37
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    • 2007
  • Proficiency test is an essential tool far ensuring analytical ability of analytical chemists and analytical institutes. Usually, the standard protocol for proficiency test is focused on acceptability of reported analytical results of participants by calculating z-scores and related diagnostic parameters. The ultimate goal of this process is to reveal the sources of variability of analytical results and to find the way to reduce their influence. In this study, the method of analysis of variance (ANOVA) was applied to the analytical data collected from qualify control departments of pharmaceutical companies in KyungIn province in Korea in the year of 2000. As influencing factors of variability of analytical results, the use of internal standards for liquid and gas chromatograpy, the educational and professional background of participants, geological locations and yearly production sizes of participating companies were evaluated. To evaluate the variability in accuracy of analytical results, absolute differences from sample mean and sample median were used and to evaluate variability in precision of individual participants, the reported standard deviation of each participant was used. As a result, the use of internal standards in gas chromatographic analysis, participants' academic background and the yearly production sizes of pharmaceutical companies showed statistically significant influence to the accuracy and the precision of the reported analytical results used in this study.

Precision Determination of Anisotropy Constant $K_1$from Magnetization Curve of Partially Aligned Unaxial Anisotropy System

  • Kim, Yoon-Bae;Kim, Hyoung-Tae
    • Journal of Magnetics
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    • v.6 no.4
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    • pp.142-144
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    • 2001
  • A method to deduce the rotational magnetization curve from experimental magnetization of partially aligned uniaxial anisotropy system has been investigated. The curve obtained by this process has been evaluated quire close to the theoretical magnetization curve compared to that obtained by linear extrapolation from high field data. This new approach offers better accuracy for the determination of magnetic anisotropy by fitting a calculated magnetization curve to the obversed one.

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Magnetic Field Standards Using Magnetic Resonance

  • Park, Po Gyu;Kim, Wan-Seop;Joo, Sung Jung;Lee, Hyung Kew
    • Journal of the Korean Magnetic Resonance Society
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    • v.21 no.1
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    • pp.7-12
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    • 2017
  • The nuclear magnetic resonance (NMR) and atomic magnetic resonance (AMR) plays a fundamental role in achieving a high accuracy of magnetic field measurements. Magnetic field unit (T) was realized based on the shielded proton gyromagnetic ratio (${\gamma}^{\prime}_P$), helium-4 gyromagnetic ratio (${\gamma}_{4He}$) and related techniques. The magnetic field standard system has been disseminated by the NMR magnetometer and electromagnet, a Helmholtz coil system, and AMR magnetometer in the nonmagnetic laboratory. A magnetic field standard below 1 mT has been developed by using Cs and Cs- $^4He$ AMR with automatic compensation of an external magnetic field noise. The standards serve for the calibration of magnetometers and support the test of sensors and materials in the range from $5{\mu}T$ to 2.0 T with (1 to 50) ${\mu}T/T$ uncertainty (k=2).

A Calibration Study of Therapeutic Ultrasound Equipment Output Intensity Accuracy

  • Yuk, Goon-Chang;Ahn, Sang-Ho;Park, So-Hyun
    • The Journal of Korean Physical Therapy
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    • v.23 no.3
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    • pp.37-42
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    • 2011
  • Purpose: The principal objective of this study was to evaluate the power output of ultrasound in Korean clinics and compare the value with Korean and global standards. Methods: A total of 69 units were measured for ultrasound power output. The normal range of power output level was ${\pm}30%$ of the output set according to KFDA standards. Device model, manufacturer, ERA, and BNR were obtained via simple questionnaires. A portable ultrasound power meter was used for output measurement. Results: 37 machines, with reported ERA values, were assessed for power output per unit area. Of these machines, 13 (37.14%) were considered to be compliant with US FDA standards at 0.5, 1.0, 1.5, $20W/cm^2$ and 18 (51.43%) were considered within KFDA standards. The remainder of the machines were outside the standard error and evidenced irregular output levels, even though most of them were the same model. Conclusion: Appropriate ultrasound intensity is incredibly important for safety and effective use. Therefore, the KFDA standards regarding ultrasound may require revision in light of global standards, including BNR and ERA additionally, attention should be paid to regular calibration for safe use in clinical practice.

Guidelines for Manufacturing and Application of Organoids: Liver

  • Hye-Ran Moon;Seon Ju Mun;Tae Hun Kim;Hyemin Kim;Dukjin Kang;Suran Kim;Ji Hyun Shin;Dongho Choi;Sun-Ju Ahn;Myung Jin Son
    • International Journal of Stem Cells
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    • v.17 no.2
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    • pp.120-129
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    • 2024
  • Recent amendments to regulatory frameworks have placed a greater emphasis on the utilization of in vitro testing platforms for preclinical drug evaluations and toxicity assessments. This requires advanced tissue models capable of accurately replicating liver functions for drug efficacy and toxicity predictions. Liver organoids, derived from human cell sources, offer promise as a reliable platform for drug evaluation. However, there is a lack of standardized quality evaluation methods, which hinders their regulatory acceptance. This paper proposes comprehensive quality standards tailored for liver organoids, addressing cell source validation, organoid generation, and functional assessment. These guidelines aim to enhance reproducibility and accuracy in toxicity testing, thereby accelerating the adoption of organoids as a reliable alternative or complementary tool to animal testing in drug development. The quality standards include criteria for size, cellular composition, gene expression, and functional assays, thus ensuring a robust hepatotoxicity testing platform.