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Optimization of Dual Layer Phoswich Detector for Small Animal PET using Monte Carlo Simulation

  • Y.H. Chung;Park, Y.;G. Cho;Y.S. Choe;Lee, K.H.;Kim, S.E.;Kim, B.T.
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.44-44
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    • 2003
  • As a basic measurement tool in the areas of animal models of human disease, gene expression and therapy, and drug discovery and development, small animal PET imaging is being used increasingly. An ideal small animal PET should have high sensitivity and high and uniform resolution across the field of view to achieve high image quality. However, the combination of long narrow pixellated crystal array and small ring diameter of small animal PET leads to the degradation of spatial resolution for the source located at off center. This degradation of resolution can be improved by determining the depth of interaction (DOI) in the crystal and by taking into account the information in sorting the coincident events. Among a number of 001 identification schemes, dual layer phsowich detector has been widely investigated by many research groups due to its practicability and effectiveness on extracting DOI information. However, the effects of each crystal length composing dual layer phoswich detector on DOI measurements and image qualities were not fully characterized. In order to minimize the DOI effect, the length of each layer of phoswich detector should be optimized. The aim of this study was to perform simulations using a simulation tool, GATE to design the optimum lengths of crystals composing a dual layer phoswich detector. The simulated small PET system employed LSO front layer LuYAP back layer phoswich detector modules and the module consisted of 8${\times}$8 arrays of dual layer crystals with 2 mm ${\times}$ 2 mm sensitive area coupled to a Hamamatsu R7600 00 M64 PSPMT. Sensitivities and variation of radial resolutions were simulated by varying the length of LSO front layer from 0 to 10 mm while the total length (LSO + LuYAP) was fixed to 20 mm for 10 cm diameter ring scanner. The radial resolution uniformity was markedly improved by using DOI information. There existed the optimal lengths of crystal layers to minimize the variation of radial resolutions. In 10 cm ring scanner configuration, the radial resolution was kept below 3.4 mm over 8 cm FOV while the sensitivity was higher than 7.4% for LSO 5 mm : LuYAP 15 mm phoswich detector. In this study, the optimal length of dual layer phoswich detector was derived to achieve high and uniform radial resolution.

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Effects of an Artificial Habitat Creation of Menyanthes trifoliata L. Using Planting Module (식재모듈을 활용한 조름나물(Menyanthes trifoliata L.) 인공서식지 조성의 효과)

  • Heo, Jinok;Kim, Heung-Tae;Kim, Cheol Min;Bae, Yeon Jae;Kim, Jae Geun
    • Journal of Wetlands Research
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    • v.17 no.1
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    • pp.53-61
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    • 2015
  • Habitat creation for endangered species Menyanthes trifoliata L. using planting module represents a habitat type such as the rhizome grows horizontally to open water at the margin of the lake. The objectives of this mesocosm experiment are habitat creation with easy construction and low management effort, and to investigate the potential of providing a habitat for aquatic macroinvertebrates. Planting modules had three different substrates of bed soil, perlite and K-SOIL (artificial lightweight soil using bottom ash). These modules were established in two different size of the tub($1170{\times}2250{\times}300mm^3$, $900{\times}1360{\times}190mm^3$). According to the monitoring results, number of leaves and coverage of M. trifoliata showed significant difference with substrate and tub size. The number of leaves showed similar growth responses in bed soil (mean 22.979) and K-SOIL (mean 28.042) substrates but growth was poor in perlite substrate (mean 1.667). The number of leaves in the large tub was more than small tub (p=0.015). Similar responses were obtained with the coverage, the length of rhizome and the number of rhizome in M. trifoliata. A total of 21 taxa of aquatic macroinvertebrates including 1,145 individuals was found in the mesocosm. The Shannon diversity index and colonization index in the mesocosm were similar to the previous studies. These results suggest that the experimental mesocosm could provide sufficient habitats for aquatic macroinvertebrates. If planting modules use bed soil or K-SOIL by planting substrate, establish that taking into account open water surfaces for M. trifoliata growth and manage about 30cm of water depth control, then habitat creation for M. trifoilata will be successful.

Design and Implementation of Medical Information System using QR Code (QR 코드를 이용한 의료정보 시스템 설계 및 구현)

  • Lee, Sung-Gwon;Jeong, Chang-Won;Joo, Su-Chong
    • Journal of Internet Computing and Services
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    • v.16 no.2
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    • pp.109-115
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    • 2015
  • The new medical device technologies for bio-signal information and medical information which developed in various forms have been increasing. Information gathering techniques and the increasing of the bio-signal information device are being used as the main information of the medical service in everyday life. Hence, there is increasing in utilization of the various bio-signals, but it has a problem that does not account for security reasons. Furthermore, the medical image information and bio-signal of the patient in medical field is generated by the individual device, that make the situation cannot be managed and integrated. In order to solve that problem, in this paper we integrated the QR code signal associated with the medial image information including the finding of the doctor and the bio-signal information. bio-signal. System implementation environment for medical imaging devices and bio-signal acquisition was configured through bio-signal measurement, smart device and PC. For the ROI extraction of bio-signal and the receiving of image information that transfer from the medical equipment or bio-signal measurement, .NET Framework was used to operate the QR server module on Window Server 2008 operating system. The main function of the QR server module is to parse the DICOM file generated from the medical imaging device and extract the identified ROI information to store and manage in the database. Additionally, EMR, patient health information such as OCS, extracted ROI information needed for basic information and emergency situation is managed by QR code. QR code and ROI management and the bio-signal information file also store and manage depending on the size of receiving the bio-singnal information case with a PID (patient identification) to be used by the bio-signal device. If the receiving of information is not less than the maximum size to be converted into a QR code, the QR code and the URL information can access the bio-signal information through the server. Likewise, .Net Framework is installed to provide the information in the form of the QR code, so the client can check and find the relevant information through PC and android-based smart device. Finally, the existing medical imaging information, bio-signal information and the health information of the patient are integrated over the result of executing the application service in order to provide a medical information service which is suitable in medical field.

Characteristics of Micro-Particle Separation according to HRT Changes (HRT 변화에 따른 미세입자 분리 특성)

  • Ahn, Kwangho;Ahn, Jaehwan;Kim, I-Tae;Kim, Seoggu;Kang, Sungwon;Park, Eunzoo;Lee, Youngsup
    • Journal of Korean Society of Environmental Engineers
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    • v.35 no.12
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    • pp.937-942
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    • 2013
  • Fluid generated within the sonic or ultrasonic waves are reflected by the wall, while the opposite direction forming a predetermined sound wave to the acoustic standing wave is referred to. In this study, the frequency of 1.0 MHz and 2.0 MHz acoustic standing wave generation module is installed in a continuous particle separation device, the laminar flow of influent, taking into account the hydraulic retention time (HRT) in accordance with changes in particle separation characteristics investigated. Operation of a standing wave in the particle separation device about $1.3{\sim}2.8^{\circ}C$ temperature is increased, but did not significantly affect the formation of standing waves. During operation, the HRT 1 hr frequency 1.0 MHz 2 hr, 4 hr longer as the particle separation efficiency (turbidity) were 64.1%, 70.0%, 74.3% and, 2.0 MHz has 58.0%, respectively, depending on HRT, 61.8%, 70.7% in the respectively. That is, the same frequency, the HRT treatment efficiency is 10% or more, depending on differences in generation and, 1.0 MHz frequency, 2 hr, 2.0 MHz 4 hr at about 70% or more of the processing efficiency can be maintained. Frequency of 1.0 MHz and 2.0 MHz operation at the same time, as a result, HRT 1 hr, 2 hr, 4 hr particle separation efficiency of 63.8%, respectively, 70.6%, 77.6%, rather than the generation of standing waves appear continuous HRT is affecting a lot of particles to separate could know.