• 한국구조물진단유지관리공학회 논문집
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• 제17권1호
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• pp.27-36
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• 2013

본 연구에서는 등대 구조물을 대상으로 한 면진기술 적용방안을 제시함으로써 지진에 대해 무방비상태에 놓여 있는 등대구조물의 지진안전도 확보방안을 제시하였다. 또한, 제안된 면진기술 적용방안을 활용하여 내진설계 이전에 지어진 등대를 대상으로 등대전체를 면진하였을 경우와 등대 렌즈만을 면진하였을 경우에 대하여 면진효과를 분석해 보았다. 해석결과, 등대 전체를 면진화하였을 경우 최대응답가속도와 층전단력 측면에서 충분한 면진효과를 얻은 반면, 등대 렌즈만을 면진화한 경우에는 렌즈부의 면진효과는 유효한 것으로 나타났으나 등대 자체의 안전이 확보되지 못한 상황에서는 등대의 파괴가 선행될 가능성이 있음에 주의할 필요가 있는 것으로 나타났다. 또한 등대전체와 렌즈를 동시에 면진화한 경우 비 면진구조 대비 유효한 면진효과는 나타내었지만, 최대응답가속도가 등대전체를 면진화한 경우보다 증가하는 경향을 나타내었으며, 렌즈의 면진화로 인한 층전단력의 감소가 미소함으로 이중면진의 적용으로 인한 실효성은 그 효과가 크지 않은 것으로 나타났다.

• Journal of Microbiology and Biotechnology
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• 제27권11호
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• pp.1952-1960
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• 2017

Recently, soybean isoflavone aglycones (i.e., daidzein and genistein) and ${\gamma}-aminobutyric$ acid (GABA) have begun to receive considerable consumer attention owing to their potential as nutraceuticals. To produce these ingredients, multiple microorganisms and their enzymes are commonly used for catalysis in the nutraceutical industry. In this work, we introduce a novel fermentation process that uses whole-cell biocatalysis to accelerate GABA and isoflavone aglycone production in doenjang (a traditional Korean soybean paste). Microbial enzymes transform soybean isoflavone glycosides (i.e., daidzin and genistin) and monosodium glutamate into soybean isoflavone aglycones and GABA. Lactobacillus brevis GABA 100 and Aspergillus oryzae KACC 40250 significantly reduced the production time with the aid of a protease. The resulting levels of GABA and daidzein were higher, and genistein production resembled the levels in traditional doenjang fermented for over a year. Concentrations of GABA, daidzein, and genistein were measured as 7,162, 60, and $59{\mu}g/g$, respectively on the seventh day of fermentation. Our results demonstrate that the administration of whole-cell L. brevis GABA 100 and A. oryzae KACC 40250 paired with a protease treatment is an effective method to accelerate GABA, daidzein, and genistein production in doenjang.

• 한국자동차공학회논문집
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• 제22권4호
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• pp.10-19
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• 2014

Despite the movement of safe traffic by the Korean government to reduce deaths in traffic accidents, the casualties increase year by year. In particular, more and more accidents and casualties are reported from car collisions from the back of the vehicles parked for managing traffic accidents on the road, cleaning main roads and medial strips, repairing roads. In order to response to these accidents, the government should take protective measures for road users. In the last decade, seventy-one cases have been reported to occur during highway repair and maintenance. As a result, eight persons were killed and seventy-six were injured, showing the high death rate of 11.3 percent. Therefore, it seems urgent to take some actions against it. The United States and European countries legislate that vehicles of road repair and maintenance should be mandatorily equipped with shock absorber at the back. Korea, however, does not have such legislative measures, which are needed at this time to protect workers on the road. This study compares the performance of the traditional shock absorber for road maintenance vehicles with that of the rear safety guard using air bag, manufactured in accordance with related laws in Korea. Based on the results of the 60km/h rear collision test, this paper proposes improvements in related laws and regulations in an attempt to reduce casualties.

• 대한의용생체공학회:의공학회지
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• 제36권4호
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• pp.103-108
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• 2015

Discrimination of Parkinson's disease (PD) from Essential tremor (ET) is often misdiagnosed in clinical practice. Since tremor is time-varying signal, and dominant and harmonic frequencies are shown in tremor only with moderate or severe symptom, there are some limitations to use frequency related features. Moreover, patients with PD or ET can suffer from both resting tremor and postural tremor. In this study, 28 patients with PD and 17 patients with ET were enrolled. Tremor was measured with accelerations on the more affected hand during resting and postural conditions. The ratio of root mean square (RMS) of resting tremor to RMS of postural tremor, the mean coefficients of autocorrelation function (ACF), and the mean of differences of two adjacent coefficients of ACF at resting and postural were calculated and compared between PD and ET. The performance showed 98% accuracy with support vector machine and leave-one-out cross validation. In addition, the method accurately differentiated the patients with tremor-dominant PD from patients with ET, with 100% accuracy. Therefore, the developed algorithm can assist clinicians in diagnosing and categorizing patients with tremor, especially, patients with mild symptom or the early stage of a disease, for proper treatment.

• Archives of Plastic Surgery
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• 제36권1호
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• pp.19-23
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• 2009

Purpose: Platelet transplantation is a novel therapeutic strategy for acceleration of wound healing. When applying platelets, efficacy of adding thrombin to stimulate growth factor release from platelets has already been proved. However, no quantitative data of the thrombin treatment has been reported. The purpose of this study was to determine the optimal thrombin concentration to maximize growth factor release of platelets. In particular, this study was designed to quantify levels of platelet derived growth factor(PDGF)-BB, which is a major growth factor contained in the platelets, in vitro. Methods: Fresh platelets were obtained from a blood bank. They were suspended in DMEM/F - 12 and incubated with thrombin of various concentrations. The concentrations of thrombin tested were 0, 6.25, 12.5, 25, 50, 100, 200, and 400 IU/ml. After 30 minutes, 1, 3, 5, and 7 days, the levels of PDGF - BB were measured using enzyme linked immunosorbent assay. Platelets from four donors were included in this study. Each sample was tested in triplicate and the mean value was used as a data for each sample. Results: The addition of thrombin increased the level of PDGF - BB. Increases in storage time of platelets resulted in decreased levels of PDGF - BB. Higher levels of PDGF were detected in consort with increased thrombin concentrations. However, there was no significant difference between samples of 200 and 400 IU/ml concentrations. Conclusion: The results indicate that adding thrombin accelerates the release of growth factors from platelets and the optimal thrombin concentration to maximize this function is 200 IU/ml.

• 한국소음진동공학회논문집
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• 제12권9호
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• pp.694-701
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• 2002

In this paper, through the study on locations of structural transducers for active control of the radiated sound from the vibrating plate, the active structural acoustic control (ASAC) system is proposed. And, for the evaluation of the proposed location, the experiment of the active structural acoustic control is implemented using the multi-channel filtered-x LMS algorithm and an additional filter (Acoustic Prediction Filter) to estimate the radiated sound using the acceleration signals of the plate. The structural transducers are piezoceramic actuator (PZT) and accelerometer. PZT is used as an actuator to reduce the vibration and the radiated sound. To maximize the control performance, each PZT actuator is located at the position that has the largest control sensitivity of the plate bending moment in the direction of x and y coordinates and the optimal PZT location is validated experimentally. Also, to find the acoustic prediction filter accurately, two accelerometers are located at the positions that have the largest radiation efficiencies of the plate, and the proposed locations are validated by simulation using the Rayleigh integral. The multi-channel filtered-x LMS algorithm is introduced to control a complex 2-D structural vibration mode. Finding the locations of structural transducers for active structural acoustic control of the radiated sound, the active structural acoustic control (ASAC) system can be presented and validated by experiments using a real time control system.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.197-202
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• 2006

The low-altitude earth observation satellite is generally equipped with high performance camera as a main payload which is vulnerable to vibration environment. During the launch process of a satellite, the combustion and jet noise of launch vehicle produce severe acoustic environment and the acoustic loads induced may damage the critical equipments of the satellite including the camera. Therefore to predict and simulate the effect of the acoustic environment which the satellite has to sustain at the lift-off event is very important process to support the load-resistive design and test-qualification of components. Statistical Energy Analysis(SEA) has been widely used to estimate the vibro-acoustic responses of the structures and gives statistical but reliable results in the higher frequency region with less modeling efforts and calculation time than the standard FEA. In this study, SEA technique has been applied to a 3-Dimensional model of a low-altitude earth observation satellite to predict the acceleration responses on the structural components induced by the high level acoustic field in the launch vehicle fairing. In addition, the expected response on each critical component panel was calculated by the classical method in consideration of the mass loading and imposed sound pressure level, and then compared with SEA results.

• 대한물리치료과학회지
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• 제10권1호
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• pp.222-231
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• 2003

The ACL(Anterior cruciate ligament) is the smallest of the four main ligaments of the knee, but it is the primary stabilizer. Injuries have a tendency to occur when the foot is firmly planted and the knee is twisted. Any sports that requires acceleration, change of direction and deceleration can increase the chances of suffering an ACL tear. The incidence of severe knee sprains that involve the ACL are at an all-time high. Since 1980, the number of these injuries have increased at least three-fold. Although the rate of increase has been much less dramatic since the middle 1980s, even the ultra-modem releasable ski binding has not been able to start reducing the incidence of ACL injuries. An ACL injury prevention program developed for downhill skiers by the Vermont Safety Research group emphasized increasing awareness of situations that can potentially result in an ACL injury and pre-planning strategies if events, leading to these situations, begin to fall in place. As part of the above study by Ettlinger et al., an educational prevent program was developed to teach these principles and thus reduce the rate of serious knee injuries. Four thousand instructors and patrol at 20 ski resorts who received the training had a 62% decline in serious knee injuries compared to a similar group that did not receive this training. Whenever you fall, try not to fully straighten your legs. Don't try to get up until you've stopped sliding(unless you are try to avoid an obstacle or other skier). When you're down, stay down. And don't land on your hand. So, if you feel yourself falling: arms forward, ski plates together, hands over knee. Then you will be able to save your ACL.

• 감성과학
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• 제1권2호
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• pp.13-22
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• 1998

The sense of touch has both objective and subjective characteristics. During hand evaluation of the fabrics. psycho physiological processes such as emotion and stimulation. On other site, the mode of touch (passive vs. active) is also capable to modulate somatosensory responses. I.e., suppress somatocensory perception during active electrocortical responses to passive and active touch of the textiles with different subjective emotional preference. The study was carried out on 36 female college students. Physiological signals were acquired by Grass and BIOPAC 100 systems with AcqKnowledge variables, namely heart rate (HR), respiratory sinus arrhythmia (RSA), pulse transit time (PTT), respiration rate (RSP) and skin conductance parameters (SCL, amplitude, risetime and number of SCRs) were analyzed for baseline and stimulation conditions. Analysis was manifested in a form of moderate HR acceleration. RSP increase, RSA decrease (lowered vagal tone), decreased PTT and increased electrodermal activity (increased SCL, several SCRs) that reflects general sympathetic activation. Parietal EEG effects (on contra-lateral side to stimulated hand)were featured by short-term alpha-blocking, slightly reduced theta, significantly increased delta and enhanced fast beta activity with few variations across stimuli. The main finding of the study was that most and least preferred textures exhibited significant differences in autonomic (HR, RSP, PTT, SCR, and at less extent in RSA and SCL) and electrocortical responses (delta, slow and fast alpha, fast beta relative power). These differences were recorded both in passive and active stimulation modes, thus demonstrating reproducibility of distinction between most and least emotionally preferred tactile stimuli, suggesting influence of psychological factors, such as emotional property of stimulus, on physiological outcome.

• 한국산학기술학회논문지
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• 제16권4호
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• pp.2370-2378
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• 2015

본 논문에서는 로봇 매니퓰레이터의 토크 최소화를 위한 궤적계획을 위해 라그랑지 보간법을 이용한 Algorithm을 제안하였다. 이를 위해 로봇 매니퓰레이터의 위치에 대한 구속조건이 주어지고 안정성이 보장되어야 한다. 라그랑지 보간법의 Runge's 현상을 회피하기 위해 Chebyshev 보간점을 이용하여 시간 보간점을 설정하였고, 이에 대응하는 최적각도를 찾아내어 라그랑지 보간법을 이용한 매끄러운 관절의 각도, 속도, 가속도 궤적을 얻을 수 있다. 로봇 매니퓰레이터의 토크 소비 최적화를 위한 성능지표를 선정하였으며, 계산된 궤적을 통해 이 성능지표가 최소값을 가지도록 반복 계산하는 과정을 거친다. 이를 통해, 토크와 성능지표를 최소화 시키는 최적의 궤적을 얻을 수 있으며, 로봇 매니퓰레이터가 작업을 수행하기 위한 움직임의 안전성을 보장한다.