• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.133-133
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• 2001

Purpose： To determine the relationship between anatomical variation at A-com. artery area an hemodynamically induced aneurysm-mimicking findings on 3D-TOF MRA clinically a experimentally. Method： Sixty-two patients who had no aneurysm at A-com artery on DSA were evalua with MRA. MRA was performed with 1.5T MR machine(Vision, Siemens). Scan parameters o MRA included TR/TE/FA=30/6.4/25$\psi$$\circledR$˙¡, 512＊192 of matrix with MIP technique. The occurrence of signal defect at shoulder area of bifurcated A-com artery on MRA was evalua for the relationship between the symmetricity of bilateral ACA and the patency of A-c artery. DSA images were acquired at both ICA and VA. To analyze hemodynamical facto of signal defect, experimental studies of MRA and DSA were peformed with elastic silic phantom using conducting pulsatile pump. We also compared the results with those o computational fluid dynamics(CFD).

• YAKHAK HOEJI
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• v.44 no.2
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• pp.155-161
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• 2000

New cephalosporin antibiotics , 3-[(4-carboxy-5-ethylthioisothiazol-3-yl)oxymethyl]-7-[(1H-tetra-zol-1-yl)acetamido]-3-cephem-4-carboxylic acid 2, 3-[(4-carboxy-5-ethylthioisothiazol-3-yl) oxymethyl]-7-[(2-aminothiazol-4-yl)acetamido]-3-cephem-4-carboxylic acid 3, 3-[(4-carb oxy-5-ethylthioisothiazol-3-yl)-oxymethyl]-7-[5-(ethylthio-3-hydroxyisothiazol-4-yl)carboxamido]-3-cephem-4-carboxylic acid 4, 3-[(4-car-boxy-5-ethylthioisothiazo1-3-yl)oxymethy1]-7-[(Z)-2-(fur-2-yl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acid 5, 7-[(Z)-2-(2-aminothiazol-4-yl)-2-[(alkoxyimino)acetamido]-3-[(4-carboxy-5-ethylthioisothiazol-3-yl)oxymethyl]-3-cephem-4-carboxylic acid 6-8 were synthesized. Antibacterial activities and structure-activity relationships of these new cephalosporin derivatives were examined. Among them, 7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)acetamido]-3-[(4-carboxy-5-ethylthylth-ioisothiazol-3-yl)oxymethyl]-3-cephem-4-carboxylic acid 7 exhibited good antibacterial activities compared to cefotaxime and ceftriaxone.

• YAKHAK HOEJI
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• v.41 no.4
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• pp.473-479
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• 1997

New cephalosporin antibiotics, 7-[(3,4-dihydro-6-methoxycarbonyl-2,2-dimethyl-2H-1,4-thiazin-3-yl)acetamido]-3-substituted-3-cephem-4-carboxylic acid derivatives 2a-2d, 7 -[(3,4-dihydro-6-ethoxycarbonyl-2,2-dimethyl-2H-1,4-thiazin-3-yl)acetamido] -3-substituted-3-cephem-4-carboxylic acid derivatives 3a-3d and 7-[(3,4-dihydro-6-methoxycarbonyl-2,2-dimethyl-2H-1,4-thiazin-3-yl-1-(S)-oxide)acetamido]-3-substituted-3-cephem-4-carboxylic acid derivatives 4a-4d were synthesized. Antibacterial activities of these new cephalosporin derivatives and the relationship between their structures and their activities were examined. Among them, 7-[(3,4-dihydro-6-methoxycaronyl-2,2-dimethyl-2H-1,4-thiazin-3-yl-1-(S)oxide)-acetamido]-3-[(1,2,3-triazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid 4d exhibited the antibacterial activities against Gram(+)and Gram(-) bacteria.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.16 no.2
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• pp.152-157
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• 2005

Background and Objectives : 10 normal Korean native speakers participated subjects to investigate the acoustic and aerodynamic study of Korean fricatives, affricates, and plosives and to make good use of the results for the patients with articulation problems. Materials and Method Their productions of [asa], [as'a], [aca], $[ac^ha]$, (ac'a), (ata) , $[at^ha]$, and [at'a] were analyzed with Lx Speech Studio Program (Laryngogrtaph Ltd, UK) for acoustic analysis and Phonatory Function Analyze. (Nagashima Ltd. Model PS 77H, Tokyo, Japan) for aerodynamic analysis. Results : The results are as follows : 1) Plosives showed higher Qx1 in vocal folds closure ratio than fricatives and affricates. 2) Tense fricatives, affricates, and plosives showed higher Qx2 in vocal folds closure ratio than asperated and 1ax. 3) Asperated showed higher Qx1 in vocal folds closure ratio than tense and 1ax. 4) Asperated showed higer peak flow rate than tense and 1ax. Conclusion This results may be helpful for treatment in articulation disorders.

• Journal of Naturopathy
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• v.7 no.1
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• pp.20-25
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• 2018

The purpose of this study was investigated to observe the relatively low amino acid mutations in six different strains of ATCC or KCTC Salmonella strains (four species and two isolates). The mutations in the strains were to be detected and compared with the genes csgA and csgB corresponding to the Thin aggregative fimbriae. Amino acid mutations in the strains were observed from Ser20→ Gly(AGT→GGT) in the csgA gene, Asp25→Ala(GAT→GCT) and Lys66→Thr(AAA→ACA) in the csgB gene. Among the six strains, the two most common amino acid variations were observed in S. typhimurium - TH strains. On the other hand, no mutation of nucleotide sequence was observed in the strains of S. typhimurium ATCC 13311 and S. typhimurium KCTC 1925. In conclusion the genes csgA and csgB in the strains may be useful for the evaluation and detection of amino acid mutation.

• YAKHAK HOEJI
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• v.42 no.4
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• pp.364-369
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• 1998

New cephalosporin antibiotics. 7-[(1H-tetrazolyl)acetamidol]-3-[(4-carboxy-3-hydroxyisothiazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid trisodium salt 2,7-[(5-ethylthio-3-hydroxyisothiazol-4-yl)carbox-amidol-3-[(4-carboxy-3-hydroxyisothiazo1-5-yl)thiomethyl)-3-cephem-4-carboxylic acid 3,7-[(2-aminothiazol-4-yl)acetamido]-3-[(4-carboxy-3-hydroxyisothiazol-5-yl]thiomethyl]-3-cephem-4-caboxylic acid 4,7-[(Z)-2-(2-aminothiazol-4-yl)-2-(alkoxyimino)acetamido)-3-[(4-carboxy-3-hydroxyisothiazol-5-yl)thiomethyl)-3-cephem-4-carboxylic acid 5-9 were synthesized. Antibacterial activities of these new cephalosporin derivatives and the relationship between their structures and activities were examined. Among them, 7-((Z)-2-(2-aminothiazol-4-yl)-2-(carboxymethoxyimino)acetamido)-3-[(4-carboxy-3-hydroxyisothiazol-5-yl)thiomethyl)-3-cephem-4-carboxylic acid 8 and 7-[(Z)-2-(2-aminothiazol-4-yl)-2-(l-carboxy-1-methylethoxyimino)acetamido]-3-[(4-carboxy-3-hydroxyisothiazol-5-yl)thiomethyl)-3-cephem-4-carboxylic acid 9 exhibited good antibacterial activities compared with those of cefotaxime and ceftriaxone.

• Journal of Welding and Joining
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• v.29 no.1
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• pp.52-58
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• 2011

In this paper, the direct bonding process between FPCB and HPCB was studied. By using an ultrasonic horn which is mounted on the ultrasonic bonding machine, it is alternatively possible to bond the gold pads attached on the FPCB and HPCB at room temperature without an adhesive like ACA or NCA. The process condition for obtaining more bonding strength than 0.6 Kgf, which is commercially required, was carried out as 40 kHz of frequency, 0.6 MPa of bonding pressure and 2 second of bonding time. The peel off test was performed for evaluating bonding strength which results in more than 0.8 Kgf.

• Journal of Korean Neurosurgical Society
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• v.60 no.2
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• pp.250-256
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• 2017

Objective : Cases of a ruptured pericallosal artery aneurysm with a high risk of intraoperative premature rupture and technical difficulties for proximal vascular control require a technique for the early and safe establishment of proximal vascular control. Methods : A combined pterional or subfrontal approach exposes the bilateral A1 segments or the origin of the ipsilateral A2 segment of the anterior cerebral artery (ACA) for proximal vascular control. Proximal control far from the ruptured aneurysm facilitates tentative clipping of the rupture point of the aneurysm without a catastrophic premature rupture. The proximal control is then switched to the pericallosal artery just proximal to the aneurysm and its intermittent clipping facilitates complete aneurysm dissection and neck clipping. Results : Three such cases are reported : a ruptured pericallosal artery aneurysm with a contained leak of the contrast from the proximal side of the aneurysm, a low-lying ruptured pericallosal artery aneurysm with irregularities on its proximal wall, and a multilobulated ruptured pericallosal artery aneurysm with the parasagittal bridging veins hindering surgical access to the proximal parent artery. In each case, the proposed combined pterional-interhemispheric or subfrontal-interhemispheric approach was successfully performed to establish proximal vascular control far from the ruptured aneurysm and facilitated aneurysm clipping via the interhemispheric approach. Conclusion : When using an anterior interhemispheric approach for a ruptured pericallosal artery aneurysm with a high risk of premature rupture, a pterional or subfrontal approach can be combined to establish early proximal vascular control at the bilateral A1 segments or the origin of the A2 segment.

• Textile Coloration and Finishing
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• v.3 no.1
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• pp.17-24
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• 1991

Polyesteramide(PEA) has been synthesized with different molar ratio of 6-aminocaproic acid(ACA) and oligo butylene terephthalate(OBT) prepared from Dimethyl terephthalate(DMT) and 1, 4-butanediol(BD) by the melt polymerization. Oligomer and polymer molecular structure were characterized by IR spectra, H'-NMR spectra. Also the thermal properties were examined by thermogravimetric analysis(TGA) and differential scanning calorimetry(DSC). DSC and TGA results exhibited that the$ T_m$ s were detectable in the vicinity of $170-220^{\circ}C$ and the Ta's were detectable in the vicinity of $380-390^{\circ}C$ . X-ray diffraction analysis results show that the synthesized polyesteramide has high degree of crystallinity.

• Journal of Digital Convergence
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• v.10 no.9
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• pp.391-396
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• 2012

The purpose of this study was to present basic research data to utilize magnetic resonance imaging (MRI) with analyzing intracerebral regional distributions of ischemic cerebrovascular disease of middle aged and oldest-old aged people. We retrospectively analyzed middle-aged group (average age of 44.2 year-old, 43 males, 26 females) and oldest-old aged group (average age of 84.7 year-old, 58 males, 71 females) who taken MRI screening for ischemic cerebrovascular disease from May 2006 year to January 2008 year. The intracerebral vascular were classified into 8 vessels, which anterior communication artery (ACoA), posterior communication artery (PCoA), anterior cerebral artery (ACA), middle cerebral artery (MCA), posterior cerebral artery (PCA), internal carotid artery (ICA), common carotid artery(CCA), and basilar artery (BA). The result of middle-aged group showed that more ischemic cerebrovascular diseases appeared in men than women, and it affected in MCA mostly. In oldest-old aged group, ischemic cerebrovascular diseases occurred evenly spaced in intracerebral region of right, left, and both vessels, and women have more than men. For men, the most occurred in ICA and for women the most occurred in MCA. Specially middle-aged group in men showed that more ischemic cerebrovascular diseases in MCA appeared than oldest-old aged group in men. It is suggested that the analysis on ischemic cerebrovascular could be helpful in the clinical diagnosis and treatment.