• 제목/요약/키워드: Ac

검색결과 8,868건 처리시간 0.041초

Immunostimulatory effect of Korean traditional medicine Acanthopanacis Cortex

  • Chang, In-Ae;Shin, Hye-Young;Kim, Youn-Chul;Yun, Yong-Gab;Park, Hyun
    • Natural Product Sciences
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    • 제13권4호
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    • pp.283-288
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    • 2007
  • Acanthopanacis Cortex (AC) has been popularly used as an herbal medicine for medical treatment of rheumatoid arthritis, insomnia, impotence and diabetes. Here, we investigated immunostimulating effects of the aqueous extract of AC on macrophage. We studied nitric oxide (NO) and tumor necrosis factor (TNF)-${\alpha}$ release in response to AC treatment, as they are important secretory products of macrophage. AC alone induce the NO and TNF-${\alpha}$ production. AC increase c-Jun NH2-terminal kinase 1/2 (JNK) and extracellular signal-regulated kinase (ERK) phosphorylation but does not p38 activation in RAW 264.7 cells. Also AC resulted in the enhanced cell-surface expression of CD80 and CD14. In addition, AC resulted in enhanced T cell-stimulatory capacity and increased T cell secretion of interferon (IFN)-gamma. After feeding with AC to mouse for 10 days, the change of $CD28^+$ and $CD40^+$ population was analyzed. AC increased $CD28^+$ population in splenocytes in vivo. These studies indicate that AC induces macrophage activation and suggest the possible use of AC in macrophage-based immunotherapies.

Proteomic and Phenotypic Analyses of a Putative YggS Family Pyridoxal Phosphate-Dependent Enzyme in Acidovorax citrulli

  • Lynn Heo;Yongmin Cho;Junhyeok Choi;Jeongwook Lee;Yoobin Han;Sang-Wook Han
    • The Plant Pathology Journal
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    • 제39권3호
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    • pp.235-244
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    • 2023
  • Acidovorax citrulli (Ac) is a phytopathogenic bacterium that causes bacterial fruit blotch (BFB) in cucurbit crops, including watermelon. However, there are no effective methods to control this disease. YggS family pyridoxal phosphate-dependent enzyme acts as a coenzyme in all transamination reactions, but its function in Ac is poorly understood. Therefore, this study uses proteomic and phenotypic analyses to characterize the functions. The Ac strain lacking the YggS family pyridoxal phosphate-dependent enzyme, AcΔyppAc(EV), virulence was wholly eradicated in geminated seed inoculation and leaf infiltration. AcΔyppAc(EV) propagation was inhibited when exposed to L-homoserine but not pyridoxine. Wild-type and mutant growth were comparable in the liquid media but not in the solid media in the minimal condition. The comparative proteomic analysis revealed that YppAc is primarily involved in cell motility and wall/membrane/envelop biogenesis. In addition, AcΔyppAc(EV) reduced biofilm formation and twitching halo production, indicating that YppAc is involved in various cellular mechanisms and possesses pleiotropic effects. Therefore, this identified protein is a potential target for developing an efficient anti-virulence reagent to control BFB.

Characterization of AC/TiO2 Composite Prepared with Pitch Binder and Their Photocatalytic Activity

  • Chen, Ming-Liang;Bae, Jang-Soon;Oh, Won-Chun
    • Bulletin of the Korean Chemical Society
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    • 제27권9호
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    • pp.1423-1428
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    • 2006
  • In this study, we have prepared pitch binded AC (activated carbon)/$AC/TiO_2$ composites photocatalysts through carbon tetrachloride solvent method. The developed samples were characterized with surface properties, structural crystallinity between AC and $AC/TiO_2$, elemental identification and photocatalytic activity. The results of the textural surface properties demonstrate that there are slight increases in the BET surface area and adsorbed volume from adsorption isotherm of composite samples with increasing of the amount of AC. The SEM results present to the characterization of porous texture on the pitch/AC/$AC/TiO_2$ composites and homogenous compositions in the particle for all the materials used. From XRD data, a weak and broad carbon peak of graphene remained rutile peaks kept with anatase structure were observed in the X-ray diffraction patterns for the pitch/AC/$AC/TiO_2$ composites. The EDX spectra show the presence of C, O and S with strong Ti peaks. Most of these samples are richer in carbon and major Ti metal than any other elements. Finally, the excellent photocatalytic activity of the pitch/AC/$AC/TiO_2$ composites between relative concentration ($c/c_o$) of MB and UV irradiation time could be attributed to the both effects between photocatalysis of the supported $AC/TiO_2$ and adsorptivity of the two kinds of carbons.

Effects of a Butanol Fraction of Alisma canaliculatum and of Selenium on Blood Glucose Levels and Lipid Metabolism in Streptozotocin-Induced Diabetic Rats

  • Kim, Myung-Wha
    • Nutritional Sciences
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    • 제6권2호
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    • pp.85-93
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    • 2003
  • The purpose of this study was to investigate the effects of a butanol fraction of fraction of Alisma canaliculatum All. Braun et Bouche (Ac), and of selenium (Se), on plasma gllucose and lipid levee in streptozotocin (STD-induced diabetic rats. Male Sprague-Dawley rats, fed the AIN-93 recommended diet, were divided into five groups: a non-diabetic control group (no STZ treatment), and four 572-induced diabetic groups which consisted of a diabetic-control group, an Ac-treated group, an Ac-Se treated group, and a Se-treated group. Diabetes was induced in the rats by an injection of STZ into the tail vein at a dose of 45 mg/kg body weight. The butanol (BuOH) fraction of Ac was orally administered at a rate of 400 mg/kg body weight for 21 days to both the Ac and Ac-Se groups. The supplementation of selenium in the Se and Ac-Se groups was achieved by adding (freshly, every day) 2 mg of Se as Na$_2$SeO$_3$ per kg of feed. The rats'body weights and hematocrit (Hct) levels were measured, along with plasma levels of glucose, insulin, cholesterol, HDL-cholesterol, triglyceride (TG), and free fatty acids (FFA). Aminotransferase activities were also analyzed. The non-diabetic rats gained weight, while the diabetic rats lost weight - except in the Ac-Se group, which maintained their initial weight. The blood glucose levels of the Ac group and the Se group were significantly lower than for the diabetic-control group. The plasma triglyceride levels were lowered when both Ac and Se were administered to diabetic rats. The concentrations of plasma FFA in the Ac-Se group were significantly lower compared with the diabetic-control group. Plasma cholesterol levels and alanine aminotransferase activity in the Ac, Ac-Se, and Se groups were significantly lower when compared with the diabetic-control group. Aspartate aminotransferase activity was significantly lower in the Se group compared to the other diabetic groups. These data show that treatment with a butanol fraction of Ac in combination with Se has no synergistic effect. Plasma glucose levels tended to be low when Se was administered to diabetic rats. Supplementation of Se in diabetic rats did not elicit a significant increase in plasma insulin levels or result in hypolipemic effects.

하이브리드 급전을 위한 다양한 가정용 교류부하의 직류특성연구 (DC Characteristics Analysis of Various AC loads for Hybrid Distribution)

  • 이영진;한동화;최중묵;정병환;김동진;최규하
    • 전력전자학회논문지
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    • 제15권3호
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    • pp.207-217
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    • 2010
  • 현재 디지털 제품의 사용의 증가로 제품 내부의 DC 전원의 사용이 증가하는 가운데 시스템의 구동전압을 공급하기 위해 기기내부에 장착된 AC/DC컨버터로 인한 입력전류의 역률저하 및 고조파 증가, 그리고 AC/DC 컨버터에서 발생하는 변환 손실 등의 문제가 발생한다. 하이브리드 배전시스템은 기존의 AC부하(전동기 부하 및 변압기 부하)와 DC 부하(컴퓨터, TV, LED조명)에 AC 와 DC 전원을 동시에 공급하며, 직류출력 전원(신재생에너지 및 배터리뱅크)과 상용전원에서 전력을 공급받아 사용자에게 DC 및 AC 전력을 공급해주는 시스템으로 상용전원의 효율을 향상시키고 신재생에너지의 사용 편의성을 올리며 가정에 AC와 DC를 동시에 공급하는데 주목적이 있다. 본 논문을 통해 DC 및 AC 동시 배전을 위해 기존 교류부하의 직류특성에 관한 연구를 하며, 하이브리드 배전의 적절한 DC 전압레벨을 선정한다.

배압 회로를 이용한 인터리브 AC/DC 컨버터의 효율 특성에 관한 연구 (A Study on the Efficiency of Intereaved AC/DC Converter using Voltage-Doubler)

  • 서상화;배진용;권순도;엄태민;김용
    • 조명전기설비학회논문지
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    • 제23권12호
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    • pp.127-135
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    • 2009
  • 본 연구에서는 2개의 인덕터를 이용한 인터리브 AC/DC 승압형 컨버터의 듀티 사이클이 0.5 이상일 때 배압 회로 특징을 나타내었다. 일반적으로 AC/DC 승압형 컨버터는 낮은 입력전압(입력 AC 110[V])이 높은 입력전압(입력 AC 220[V])에 비하여 낮은 효율을 갖는다. 제안된 인터리브 AC/DC 승압형 컨버터는 낮은 입력전압에서 배압 회로로 동작함으로 인하여 낮은 입력전압을 사용하는 기존의 컨버터와 비교하여 높은 역률과 향상된 효율을 갖는다. 본 연구에서는 배압 회로 동작하는 하는 인터리브 AC/DC 승압형 컨버터를 제안하고, 모드별 해석과 특성을 논의하였으며, 300[W]급 시작품을 제작하여 그 타당성을 검증하였다.

Two-Switch Auxiliary Resonant DC Link Snubber-Assisted Three-Phase Soft Switching PWM Sinewave Power Conversion System with Minimized Commutation Power Losses

  • Nagai, Shinichiro;Sato, Shinji;Ahmed, Tarek;Nakaoka, Mutsuo
    • Journal of Power Electronics
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    • 제3권4호
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    • pp.249-258
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    • 2003
  • This paper presents a high-efficient and cost effective three-phase AC/DC-DC/AC power conversion system with a single two-switch type active Auxiliary Resonant DC Link (ARDCL) snubber circuit, which can minimize the total power dissipation. The active ARDCL snubber circuit is proposed in this paper and its unique features are described. Its operation principle in steady-state is discussed for the three phase AC/DC-DC/AC converter, which is composed of PWM rectifier as power factor correction (PFC) converter, sinewave PWM inverter. In the presented power converter system not only three-phase AC/DC PWM rectifier but also three-phase DC/AC inverter can achieve the stable ZVS commutation for all the power semiconductor devices. It is proved that the proposed three-phase AC/DC-DC/AC converter system is more effective and acceptable than the previous from the cost viewpoint and high efficient consideration. In addition, the proposed two-switch type active auxiliary ARDCL snubber circuit can reduce the peak value of the resonant inductor injection current in order to maximize total system actual efficiency by using the improved DSP based control scheme. Moreover the proposed active auxiliary two-switch ARDCL snubber circuit has the merit so that there is no need to use any sensing devices to detect the voltage and current in the ARDCL sunbber circuit for realizing soft-switching operation. This three-phase AC/DC-DC/AC converter system developed for UPS can achieve the 1.8% higher efficiency and 20dB lower conduction noise than those of the conventional three-phase hard-switching PWM AC/DC-DC/AC converter system. It is proved that actual efficiency of the proposed three-phase AC/DC-DC/AC converter system operating under a condition of soft switching is 88.7% under 10kw output power.

출력이 직렬 결합된 단상 Quasi Z-소스 AC-AC 컨버터 (A Single-Phase Quasi Z-Source AC-AC Converter with a Series Connection of the Output Terminals)

  • 엄준현;정영국;임영철;최준호
    • 전력전자학회논문지
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    • 제16권5호
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    • pp.415-429
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    • 2011
  • 본 연구에서는 출력이 직렬 연결된 단상 quasi Z-소스 AC-AC 컨버터를 제안하였다. 제안된 시스템은 단상quasi Z-소스 AC-AC 컨버터 2대의 입력 단을 병렬로 연결하고 출력 단을 직렬로 연결한 구조로 되어 있으며, 역상 모드와 동상 모드 별 전류 흐름과 출력전압의 형성 과정을 나타내었다. DSP로 제어되는 실험 시스템을 제작하여 PSIM시뮬레이션 결과와 비교 분석하였다. 그 결과 각 모드별로 듀티 비를 제어하여 원하는 출력 전압을 벅-부스트 할 수 있었다. 컨버터 1대가 단독으로 운전한 경우에 비하여, 각각의 모드에 대하여 부하 저항의 증가에 따른컨버터 효율과 입력 역률을 제안된 방법에 의하여 개선할 수 있었다. 또한 역상 모드의 경우, 일정 부하에서 컨버터의 효율과 입력 역률을 각각 10[%]와 35[%]정도 개선하였으며, 특히 부하 저항이 변동하는 과도상태에서도 일정한 출력 전압을 유지할 수 있었다.

오존촉매산화공정에서 금속 담지촉매에 의한 수산화라디칼 생성연구 (A Study on the Formation of OH Radical by Metal-supported Catalyst in Ozone-catalytic Oxidation Process)

  • 이선희;최재원;이학성
    • 공업화학
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    • 제29권4호
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    • pp.432-439
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    • 2018
  • 활성탄의 화학적 흡착 및 오존촉매반응의 작용기를 향상시키기 위해 Fe, Co, Mn 및 Pd 금속들을 활성탄에 담지하여 금속촉매 활성탄을 제조하였다. 고급산화공정의 실험결과에서 페놀 분해속도, 용존 오존 분해율 및 TOC (총유기탄소) 제거율은 Pd-AC > Mn-AC > Co-AC > AC > Fe-AC의 순서로 나타났다. BET 분석에서 금속담지활성탄의 물리적 특성은 오존촉매반응에 영향을 미치지 않았으며, 촉매효과는 담지한 금속의 종류에 따라 상이한 결과를 나타내었다. RCT (생성된 OH radical과 오존의 비율) 값 측정은 OH radical과 쉽게 반응하지만 오존과는 매우 느리게 반응하는 probe compound로 알려진 파라-클로로벤조산(p-chlorobenzoic acid)의 분해결과로부터 구할 수 있었으며, 오존단독 공정은 $5.48{\times}10^{-9}$, 활성탄 공정은 $1.47{\times}10^{-8}$로 측정되었고, Fe-AC, Co-AC, Mn-AC 및 Pd-AC 공정은 각각 $2.13{\times}10^{-9}$, $1.51{\times}10^{-8}$, $4.77{\times}10^{-8}$$5.58{\times}10^{-8}$로 측정되었다.

무가압함침법에 의한 $Al_2O_{3p}$/AC8A 복합재료의 제조 및 특성 (Fabrication and Characteristics of $Al_2O_{3p}$/AC8A Composites by Pressureless Infiltration Process)

  • 김재동;고성위;정해용
    • Composites Research
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    • 제13권6호
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    • pp.1-8
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    • 2000
  • 무가압함침법에 의한 $Al_2O_{3p}$/AC8A 복합재료의 제조와, 제조법과 관련하여 부가적인 Mg의 첨가와 강화상의 부피분율이 $Al_2O_{3p}$/AC8A복합재료의 기계적 성질과 마모저항에 미치는 영향을 조사하였다. 강화상 입자와 기지재료의 일부를 분말로 조합한 혼합분말 속으로 기지금속을 자발적으로 침투시켜 부피분율이 20~40%인 $Al_2O_{3p}$/AC8A 복합재료를 제조할 수 있었다. 그러나 강화상의 부피분율이 40%인 복합재료의 경우 기공율의 상승으로 복합재료의 강도는 저하하였다. Mg의 첨가량이 5~7wt% 일 때 가장 높은 강도를 나타냈으며, 경도는 Mg 첨가량의 증가에 따라 점진적으로 상승하였다. $Al_2O_{3p}$/AC8A복합재료는 저속에서 기지재료에 비해 내마모성이 저하하였으나, 고속에서는 AC8A합금에 비해 약 5.5배의 우수한 내마모성을 나타냈다. 마모기구의 관찰에 의해 부피분율 20% $Al_2O_{3p}$/AC8A복합재료의 경우 연삭마모가 주된 마모기구임을 알 수 있었으며, 부피분율 40% $Al_2O_{3p}$/AC8A복합재료는 높은 기공율로 인한 마모 가중으로 저속에서도 경미한 응착마모가 관찰됐고 마찰 속도가 증가함에 따라 격심한 마모로 진행되었다.

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