• Title/Summary/Keyword: Absolute Risk

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Pneumocystis jirovecii pneumonia in pediatric patients: an analysis of 15 confirmed consecutive cases during 14 years

  • Kim, Kyung-Ran;Kim, Jong Min;Kang, Ji-Man;Kim, Yae-Jean
    • Clinical and Experimental Pediatrics
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    • v.59 no.6
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    • pp.252-255
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    • 2016
  • Purpose: Pneumocystis jirovecii pneumonia occurs in various immunocompromised patients. Despite the prophylaxis strategies in clinical practice, certain patients develop P. jirovecii pneumonia. This study was performed to investigate pediatric cases with P. jirovecii pneumonia in a single center. Methods: We identified pediatric patients younger than 19 years with microbiologically confirmed P. jirovecii pneumonia from January 2000 to February 2014. A retrospective chart review was performed. Results: Fifteen episodes of P. jirovecii pneumonia in 14 patients were identified with median age of 8.3 years (range, 0.4-18.6 years). Among these patients, 11 patients had hematology-oncology diseases, 2 had primary immunodeficiency disorders (one with severe combined immunodeficiency and the other with Wiskott Aldrich syndrome), 1 had systemic lupus erythematosus and 1 received kidney transplant. Four patients were transplant recipients; 1 allogeneic and 2 autologous hematopoietic cell transplant and 1 with kidney transplant. The median absolute lymphocyte count at the diagnosis of P. jirovecii pneumonia was $5,156cells/mm^3$ (range, $20-5,111cells/mm^3$). In 13 episodes (13 of 15, 86.7%), patients were not receiving prophylaxis at the onset of P. jirovecii pneumonia. For treatment, trimethoprim/sulfamethoxazole was given as a main therapeutic agent in all 15 episodes. Steroid was given in 9 episodes (60%). Median treatment duration was 15 days (range, 4-33 days). Overall mortality at 60 days was 35.7% (5 of 14). Conclusion: Majority of our patients developed P. jirovecii pneumonia while not on prophylaxis. Continuous efforts and more data are needed to identify high risk patients who may get benefit from P. jirovecii pneumonia prophylaxis.

Theoretically Informed Correlates of Hepatitis B Knowledge among Four Asian Groups: The Health Behavior Framework

  • Maxwell, Annette E.;Stewart, Susan L.;Glenn, Beth A.;Wong, Weng Kee;Yasui, Yutaka;Chang, L. Cindy;Taylor, Victoria M.;Nguyen, Tung T.;Chen, Moon S.;Bastani, Roshan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1687-1692
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    • 2012
  • Background: Few studies have examined theoretically informed constructs related to hepatitis B (HBV) testing, and comparisons across studies are challenging due to lack of uniformity in constructs assessed. The present analysis examined relationships among Health Behavior Framework factors across four Asian American groups to advance the development of theory-based interventions for HBV testing in at-risk populations. Methods: Data were collected from 2007-2010 as part of baseline surveys during four intervention trials promoting HBV testing among Vietnamese-, Hmong-, Korean- and Cambodian-Americans (n = 1,735). Health Behavior Framework constructs assessed included: awareness of HBV, knowledge of transmission routes, perceived susceptibility, perceived severity, doctor recommendation, stigma of HBV infection, and perceived efficacy of testing. Within each group we assessed associations between our intermediate outcome of knowledge of HBV transmission and other constructs, to assess the concurrent validity of our model and instruments. Results: While the absolute levels for Health Behavior Framework factors varied across groups, relationships between knowledge and other factors were generally consistent. This suggests similarities rather than differences with respect to posited drivers of HBV-related behavior. Discussion: Our findings indicate that Health Behavior Framework constructs are applicable to diverse ethnic groups and provide preliminary evidence for the construct validity of the Health Behavior Framework.

The Effects of Skeletal Muscle Mass and Muscle Fatigue on the Proprioceptive Position Sense of the Knee Joint (뼈대근육량과 근피로가 무릎관절 고유수용성 위치감각에 미치는 영향)

  • Park, Sookyoung;Park, Kanghui
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.2
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    • pp.139-147
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    • 2020
  • Purpose : Proprioceptive position sense plays a key role in providing joint stability, and multiple factors are related to proprioceptive position sense. Thus, this study aimed to determine the effects of body composition, particularly skeletal muscle mass on proprioceptive position sense following muscle fatigue. Methods : Healthy female subjects agreed to have their body composition analyzed. Only subjects who had 18.5-22.9 kg/㎡ of BMI (body mass index) were included in this study, and the participants were divided into two groups by skeletal muscle mass level. The experimental group had a level of skeletal muscle lower than the standard level (n=9), while the control group showed a standard or high level of skeletal muscle mass (n=11). To determine the change in proprioceptive position sense of the knee joint, the absolute angle error (AAE) was evaluated following muscle fatigue on low extremity. The muscle fatigue was induced by isokinetic resistance exercise program of Biodex system. AAE was measured by the Biodex system and compared the result before and after muscle fatigue. Results : The experimental group showed a significant AAE difference between before (3.16±2.48 °) and after (5.40±2.61 °) muscle fatigue. In addition, there was a AAE difference between the experimental (5.40±2.61 °) and control groups (3.53±1.67 °) after fatigue; however, there was no significance. Those results indicated that low level of skeletal muscle mass might influence the proprioceptive position sense of the knee joint after muscle fatigue. Conclusion : Thus, maintaining the proper level of skeletal muscle mass is pivotal to reduce the risk of injury following muscle fatigue in ADL or sport activities.

Socioeconomic Disparities in Breast Cancer Screening among US Women: Trends from 2000 to 2005

  • Kim, Jae-Young;Jang, Soong-Nang
    • Journal of Preventive Medicine and Public Health
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    • v.41 no.3
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    • pp.186-194
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    • 2008
  • Objectives : This study describes trends in the socioeconomic disparities in breast cancer screening among US women aged 40 or over, from 2000 to 2005. We assessed 1) the disparities in each socioeconomic dimension; 2) the changes in screening mammography rates over time according to income, education, and race; and 3) the sizes and trends of the disparities over time. Methods : Using data from the Behavioral Risk Factor Surveillance System (BRFSS) from 2000 to 2005, we calculated the age-adjusted screening rate according to relative household income, education level, health insurance, and race. Odds ratios and the relative inequality index (RII) were also calculated, controlling for age. Results : Women in their 40s and those with lower relative incomes were less likely to undergo screening mammography. The disparity based on relative income was greater than that based on education or race (the RII among low-income women across the survey years was 3.00 to 3.48). The overall participation rate and absolute differences among socioeconomic groups changed little or decreased slightly across the survey years. However, the degree of each socioeconomic disparity and the relative inequality among socioeconomic positions remained quite consistent. Conclusions : These findings suggest that the trend of the disparity in breast cancer screening varied by socioeconomic dimension. Continued differences in breast cancer screening rates related to income level should be considered in future efforts to decrease the disparities in breast cancer among socioeconomic groups. More focused interventions, as well as the monitoring of trends in cancer screening participation by income and education, are needed in different social settings.

A Study on the Prediction of Risk Degree of Side Collapes Due to Excavation (기초굴착에 따른 측면붕괴의 위험성 예측에 관한 연구)

  • 강준묵;한승희;이재기
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.9 no.1
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    • pp.17-25
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    • 1991
  • A foundation excavation is necessarily included in construction works of structures. Involving the dangers of collapse, large-scaled excavation walls require periodic deformation measurements. As only relative displacements and acquired and surface measurements can not be made with the conventional measuring methods, the up-to-date method which can overcome these weaknesses is required urgently. Terrestrial photogrammetry is the method by which absolute deformation amounts of many points can be taken out at a distance from object in short time. The objective of this study is to suggest application propriety of terrestrial photogrammetry to the measurement of excavation walls. For it, we devised same position photography(S.P.P) and possibility of SPP proved through basic experiment. SPP was very speedy photographing method. We found out the fact that as the degree of overlap increase, accuracies of results increase. As a result of applying to excavation side-wall, we detected consistent displacement in 3 dimension each direction within the limits expectional accuracy. If control surveying could be carried out more quickly and accurately, the deformation displacement could be analyzed more effectively.

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Measurement and Evaluation of Flash Point for the DMF Contained Organic Solvent Mixtures (DMF함유 혼합 유기용제에 대한 인화점의 측정과 평가)

  • Lee, Jung-Suk;Han, Ou-Sup;Lee, Keun-Won
    • Fire Science and Engineering
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    • v.33 no.4
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    • pp.9-15
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    • 2019
  • The flash points of DMF based organic solvent mixtures used in the synthetic leather manufacturing process were measured. The test group was composed of seven types of solvent mixtures, which included DMF, toluene, and MEK. Each flash point was tested according to the international standard test methods of KS M 2010. The flash points were then predicted using some prediction models and compared with the measured data. From the analysis results, the binary mixtures with a mole ratio of less than approximately 0.7 showed that the measured values were under 25 ℃. This showed that the expectation for the flammable risk lowering effects due to the mixing of high flash point materials was reduced. In addition, the predicted values were evaluated using the average absolute deviation (A.A.D). The results showed that the Le Chatelier's models had an "A.A.D" of 1.95 ℃ and were the closest to the measured values.

Estimating the Socioeconomic Costs of Child Poverty (아동 빈곤의 사회경제적 비용 추계)

  • Kim, Soo Jung;Chung, Ick-Joong
    • Korean Journal of Social Welfare
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    • v.69 no.3
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    • pp.9-33
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    • 2017
  • This study estimated the socioeconomic costs of child poverty. Based on previous studies, the present study organized component categories for direct and indirect costs of child poverty, and estimated the cost of each category in 2015 through the collection of existing data and Delphi survey techniques among experts. The total socioeconomic costs of child poverty were compared to Korea's GDP. The results of this study were as follows. First, the socioeconomic costs of child poverty in Korea in 2015 ranged from 55 trillion KW(3.5% of GDP) to 99 trillion KW(6.5% of GDP). Second, the indirect socioeconomic costs of child poverty are much higher than the direct costs. Third, among the total cost categories, costs related to productivity loss and unemployment accounted for the largest portion of both the socioeconomic costs based upon absolute poverty and relative poverty. Crime costs are the second largest. Based on these results, we discussed the importance of early intervention for children in poverty; implementation of two-generation program that intervenes simultaneously with parents and children; and long-term, continuous and integrated intervention for high-risk groups such as poor children.

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The long-term agricultural weather forcast methods using machine learning and GloSea5 : on the cultivation zone of Chinese cabbage. (기계학습과 GloSea5를 이용한 장기 농업기상 예측 : 고랭지배추 재배 지역을 중심으로)

  • Kim, Junseok;Yang, Miyeon;Yoon, Sanghoo
    • Journal of Digital Convergence
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    • v.18 no.4
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    • pp.243-250
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    • 2020
  • Systematic farming can be planned and managed if long-term agricultural weather information of the plantation is available. Because the greatest risk factor for crop cultivation is the weather. In this study, a method for long-term predicting of agricultural weather using the GloSea5 and machine learning is presented for the cultivation of Chinese cabbage. The GloSea5 is a long-term weather forecast that is available up to 240 days. The deep neural networks and the spatial randomforest were considered as the method of machine learning. The longterm prediction performance of the deep neural networks was slightly better than the spatial randomforest in the sense of root mean squared error and mean absolute error. However, the spatial randomforest has the advantage of predicting temperatures with a global model, which reduces the computation time.

Forecasting the BDI during the Period of 2012 (2012 BDI의 예측)

  • Mo, Soo-Won
    • Journal of Korea Port Economic Association
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    • v.27 no.4
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    • pp.1-11
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    • 2011
  • In much the same way as the US Lehman crisis of 2008-2009 severely impacted the European economy through financial market dislocation, a European banking crisis would materially impact the US economy through a generalized increase in global risk aversion. A deepening of the European crisis could very well derail the US economic recovery and have a harmful impact on the Asian economies. This kind of vicious circle could be a bad news to the shipping companies. The purpose of the study is to predict the Baltic Dry Index representing the shipping business during the period of 2012 using the ARIMA-type models. This include the ARIMA and Intervention-ARIMA models. This article introduces the four ARIMA models and six Intervention-ARIMA models. The monthly data cover the period January 2000 through October 2011. The out-of-sample forecasting performance is also calculated. Forecasting performance is measured by three summary statistics: root mean squared percent error, mean absolute percent error and mean percent error. The root mean squared percent errors, however, are somewhat higher than normally expected. This reveals that it is very difficult to predict the BDI The ARIMA-type models show that the shipping market will be bearish in 2012. These pessimistic ex-ante forecasts are supported by the Hodrick-Prescott filtering technique.

Presumption Method for Optimum Correction Rate of Total Construction Cost Using the Median based on Historical Data Analysis in Public Office Buildings (공공건축물 실적자료 분석에 따른 중위수를 활용한 총공사비의 적정보정율 추정방법)

  • Yim, Jin-Ho;Park, Jun-Mo;Kim, Ok-Kyue
    • Journal of the Korea Institute of Building Construction
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    • v.14 no.5
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    • pp.415-422
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    • 2014
  • There is growing difference between a planned value and an actual cost for increasing as an risk of construction cost. A construction cost index is an alternative to redeem a problem, but it is still very difficult to reduce an actual differential as a price fluctuation. Furthermore an existing theory of a construction cost index is overly complex, and is unsuitable for using in working-level. This study suggests an optimum correction rate in respect of a total construction cost. It is analyzing the actual cost of 53 public buildings that the Public Procurement Service ordered. The objects are main processes that include architectural works, mechanical works, electrical works, telecommunication works, and service facilities. It is compared a total construction cost based on absolute error rate using the median from frequentist principle. For this, it is selected the suitable regression model and set a correction rate.