• Journal of Trauma and Injury
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• 제18권2호
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• pp.81-86
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• 2005

Background: Cardiac troponin I (cTnI) is a sensitive cardiac marker of myocardial injury. In normal coronary angiogram, positive cTnI values may be detected in various events such as sepsis, stroke, trauma and so on. To investigate characteristics of cTnI positive group in trauma patients, we designed this study between cTnI positive group and cTnI negative group. Method: Trauma patients who visited emergency room within 24 hours after accidents were included. Patients who had renal failure, acute coronary syndrome, sepsis, spontaneous SAH were excluded. Retrospective study of 97 trauma patients was done. We investgated ISS (injury severity score), positive cTnI, EKG abnormality, shock class, ICU admission rate and mortality. Result: In comparing with non chest trauma group, chest trauma group, whose chest AIS (Abbreviated Injury Score) is more than 3 point, had significant values in ISS, positive cTnI, EKG abnormality, shock class and ICU admission rate. Also, in non chest trauma group, we found several patients whose cTnI level was positive. When non chest trauma group was divided into two subgroups, the mortality and shock class of positive cTnI group were higher than that of negative cTnI group. When all trauma patients were divided into two groups, a positive cTnI group had higher values in ISS, shock class, ICU admission rate and mortality than that in a negative cTnI group. Conclusion: We found that cTnI were positive in patients of cardiac contusion but also in various trauma cases. In non chest trauma patients, we assumed that hypotension caused cTnI elevating. The cTnI could play a role in predicting prognosis in trauma patients.

• Journal of Chest Surgery
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• 제34권12호
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• pp.937-943
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• 2001

배경 : 본 연구의 목적은 흉골골절에서 심혈관계 동반 손상의 예측인자를 알아내고 응급 심장 초음파검사의 적응증을 제시하고자 하였다. 대상 및 방법 : 1994년 3월부터 5년간 이화여자대학교 부속 목동병원 응급실을 통해 입원한 흉골골절로 입원한 40명의 환자들을 대상으로 후향적 분석을 시행하였다. 예측인자로서는 1) 안전띠 착용의 유무, 2) 동반 손상의 유무, 3) 심혈관계 질환의 병력 유무, 4) 내원시 환자의 RTS(Revised Trauma Score) 4가지를 대상으로 분석하였다. 또한 심혈관계 손상의 동반 유무를 파악하기 위하여 일반적으로 사용하는 심전도와 흉부 단순 촬영 및 심근 효소의 분획을 조사하였으며, 그 결과에서, 흉골골절에서 응급 심장 초음파 검사의 적응증을 추론하였다. 결과 : 흉골골절에서 심혈관계 손상의 동반 유무를 나타내는데 통계적으로 의미가 있다고 나온 인자로는 심혈관계 과거 병력이 있는 경우와 입원시 RTS의 이상을 들 수 있다. 응급 심장 초음파검사의 시행은 예측인자들과 심전도와 흉부 단순 촬영 및 심근 효소의 분획 같은 일반적으로 사용하는 검사 결과에 따라 시행하였다. 흉골골절 환자에서 응급 심장 초음파검사의 적응으로 1) 의미 있는 예측 인자의 변화가 없더라도 두 개 이상의 검사에서 이상소견을 보이던가, 2) 예측인자의 의미있는 변화가 하나 이상 나오는 경우를 들 수 있다. 결론 : 흉골골절 환자에서 심혈관계의 과거 병력과 초기활력 징후가 심혈관 동반 손상 유무를 중요하게 나타날 수 있으며, 필요한 경우, 응급 심장 초음파 검사를 시행하여 조기에 확진을 내리는 것이 중요하다고 생각한다.

• Journal of Korean Neurosurgical Society
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• 제54권3호
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• pp.164-174
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• 2013

Objective : The aim of this study was to determine 30-day mortality and 6-month functional recovery rates in spontaneous intracerebral hemorrhage (S-ICH) patients undergoing hemodialysis treatment for end-stage renal disease (ESRD), and to compare the outcomes of these patients and S-ICH patients without ESRD. Methods : The medical records of 1943 S-ICH patients from January 2000 to December 2011 were retrospectively analyzed with focus on demographic, radiological, and laboratory characteristics. Results : A total of 1558 supratentorial S-ICH patients were included in the present study and 102 (6.5%) were ESRD patients. The 30-day mortality of the S-ICH patients with ESRD was 53.9%, and 29.4% achieved good functional recovery at 6 months post-S-ICH. Multivariate analysis showed that age, Glasgow Coma Scale (GCS) score, pupillary abnormality, ventricular extension of hemorrhage, hemorrhagic volume, hematoma enlargement, anemia, and treatment modality were independently associated with 30-day mortality in S-ICH patients with ESRD (p<0.05), and that GCS score, volume of hemorrhage, conservative treatment, and shorter hemodialysis duration was independently associated with good functional recovery at 6 months post-S-ICH in patients with ESRD (p<0.05). Conclusion : This retrospective study showed worse outcome after S-ICH in patients with ESRD than those without ESRD; 30-day mortality was four times higher and the functional recovery rate was significantly lower in S-ICH patients with ESRD than in S-ICH patients without ESRD.

• 대한족부족관절학회지
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• 제24권1호
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• pp.14-18
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• 2020

Purpose: Chronic ankle instability is a very common abnormality of the ankle, but there is still controversy regarding its evaluation criteria. The stress view has difficulties in reflecting the patient's symptoms and treatment progress. Therefore, this study examined the relationship between the center of pressure (COP) measured by a pedobarograph and the symptoms of the patient. Materials and Methods: Thirty patients with chronic ankle instability from February to August 2018 were included. Each patient was surveyed with the foot and ankle outcome score (FAOS). The COP was measured with a foot pressure scanner, and the travel distance and ellipse area of the COP were calculated. Each patient was measured on one foot and on two feet with his or her eyes closed and open. The relationship between the COP measurement and FAOS score was analyzed using the Pearson correlation coefficient. Results: The participants were consisted of 21 male and nine female, with a mean age of 30 years, mean weight of 72 kg, and mean foot size of 259 mm. With the eyes open, the correlation coefficient between the FAOS and travel distance of the affected side was -0.394 (p<0.05) and that between the FAOS and the ellipse area of the affected side was -0.425 (p<0.05). On the other hand, no significant correlations were found between the travel distance and ellipse area of the affected side when patients closed their eyes. Conclusion: Measurement of the COP using foot pressure scanner could evaluate objectively patients with chronic ankle instability, with measurements in patients with their eyes open being more significant. Based on the findings of this study, an analysis of the COP with the patients with their eyes open and standing on one foot may help determine the management strategy and assess the progress of the patients.

• 한국임상수의학회지
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• 제34권1호
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• pp.13-17
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• 2017

This study evaluated the efficacy and safety to determine the therapeutic responses of oclacitinib in canine atopic dermatitis (CAD) and identified factors related to the therapeutic response. Overall, 13 dogs with CAD were treated with oclacitinib for 56 days. Owners and veterinarians assessed visual analog scale (VAS) scores of pruritus and dermatitis. The examined dogs were grouped according to treatment success and failure based on changes in the VAS scores. To identify factors related to the therapeutic responses of oclacitinib, signalments (breed, sex, age, and body weight), mean progression time of CAD, mean Owner and Veterinarian VAS scores at day 0, and preexisting infection rate were compared between the two groups. Among the 13 dogs, 7 (53.8%) met the criteria of treatment success. In the success group, the Owner VAS scores were significantly lower from day 6 to 56 compared with the score at day 0 (P < 0.05). Additionally, the Veterinarian VAS scores were significantly decreased at days 14 and 42 compared with the score at day 0 (P < 0.05). There were no changes in hematological indices after the administration of oclacitinib. The most common abnormality reported was otitis externa (30.8%), followed by pyoderma (23.1%), and vomiting (7.7%). Factors related to responses of oclacitinib were not identified. This study demonstrated that oclacitinib was safe and moderately effective in dogs with CAD. This is the first report of the clinical application of oclacitinib in South Korea.

• Journal of Veterinary Science
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• 제21권6호
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• pp.82.1-82.10
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• 2020

Background: The clinical presentation of horses with back pain (BP) vary considerably with most horse's willingness to take part in athletic or riding purpose becoming impossible. However, there are some clinical features that are directly responsible for the loss or failure of performance. Objectives: To investigate the clinical features of the thoracolumbar region associated with BP in horses and to use some of the clinical features to classify equine BP. Methods: Twenty-four horses comprised of 14 with BP and 10 apparently healthy horses were assessed for clinical abnormality that best differentiate BP from normal horses. The horses were then graded (0-5) using the degree of pain response, muscular hypertonicity, thoracolumbar joint stiffness and overall physical dysfunction of the horse. Results: The common clinical features that significantly differentiate horses with BP from non-BP were longissimus dorsi spasm at palpation (78.6%), paravertebral muscle stiffness (64.3%), resist lateral bending (64.3%), and poor hindlimb impulsion (85.7%). There were significantly (p < 0.05) higher scores for pain response to palpation, muscular hypertonicity, thoracolumbar joint stiffness and physical dysfunction among horses with BP in relation to non-BP. A significant relationship exists between all the graded abnormalities. Based on the cumulative score, horses with BP were categorized into mild, mild-moderate, moderate and severe cases. Conclusions: BP in horse can be differentiated by severity of pain response to back palpation, back muscle hypertonicity, thoracolumbar joint stiffness, physical dysfunctions and their cumulative grading score is useful in the assessment and categorization of BP in horses.

• 한국빅데이터학회지
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• 제6권2호
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• pp.29-38
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• 2021

항공안전관리에서 항공기 경로 이탈은 큰 사고로 이어질 수 있는 위험한 요인이다. 본 연구에서는 항공기 경로 이탈 문제를 예방하기 위해 클러스터링을 통해 항적을 분류하고, 클러스터 중심과의 거리를 계산하여 이상 점수를 산출하고자 한다. 1년 동안 수신된 ADS-B 항적 자료에서 공항을 기준으로 근방 100km 이내 항적을 추출하여 연구를 진행했다. 항적은 선형 보간법을 이용하여 벡터화하였다. 위도·경도·고도 3차원 좌표 자료를 사용하였다. PCA를 통해 전체 데이터 분산 90% 이상을 나타내는 축으로 차원을 축소하였고, k-평균 군집화, 계층적 군집화, PAM 기법을 적용하였다. 클러스터 개수는 실루엣 측도를 사용하여 선택하였고, 클러스터 중심과의 거리를 계산하여 이상 점수를 산출하였다. 본 연구에서는 각 클러스터 기법별로 클러스터 개수를 비교해보고, 실루엣 측도를 통해 클러스터링 결과를 평가하고자 한다.

• 대한치과교정학회지
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• 제21권2호
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• pp.287-307
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• 1991

This study aimed at examining speech defects of openbite patients, which were analized in terms of formant frequency for vowels and word pronunciation length for consonants. In addition, the upper and lower lip (perioral m.) activity was tested by the EMG. The tongue force was measured by the strain gauge, and the speech discrimination test was carried out. One experimental group and one control group were used for this study and they were respectively composed of six female openbite patients and six normal-occlusion females. Eight monophthongs, two fricatives and two affricatives were chosen for speech analysis. Speeches of the above-mentioned groups were recorded and then analized by the ILS/PC-1 software. Four hundred most frequently used monosyllables were also chosen for discrimination score. Openbite patients showed the following characteristics: 1. Abnormality in case of /a/, $/\varepsilon/$, /e/, /i/ $F_2$ and /e/, /a/ $F_1$. 2. Significantly elongated length in their pronunciation of /h/ and $/C^h/$ and somewhat elongated length also in their pronunciation of /s/ and /c/. 3. Significant upper lip activity according to the EMG test during pronunciation of the bilabial consonants. 4. Relatively weak tongue force according to the strain gauge measurement. 5. According to the speech discrimination test, high rate of misarticulation in case of (a) initial /p/ /s'/ and /ts'/, (b) /a/,$/\varepsilon/$,/e/,/je/,/o/, $/\phi/$,/jo/,/u/,/we/, and /i/ (c) final (equation omitted).

• 대한한의학회지
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• 제28권2호통권70호
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• pp.13-21
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• 2007

Objective : Halitosis, or bad breath, is a common concern for many people. The aim of this study was to investigate clinical characteristics of halitosis patients and correlation with their various associated elements. Methods: We surveyed 169 halitosis patients by reviewing questionnaires from the Halitosis Clinic in the Hospital of Oriental Medicine, Kyunghee University from January 2004 to March 2006. The questionnaires contained various items including sex, age, history of smoking and alcohol intake, duration of symptoms in a week, time and condition of severe halitosis, suggestive origin of halitosis, taste abnormality, oral hygiene, self-assessed halitosis severity, dry mouth, postnasal drip, tonsillolith, globus pharyngeus, reflux sensation, too much gas and Winkel tongue coating index. Volatile sulfur compounds were measured with a $Halimeter^{\circledR}$. Results : The halitosis patients actively carried out management methods such as non-smoking, moderation in drink, teeth brushing and tongue scraping in order to decrease their oral malodor. Tongue coating significantly affected the $Halimeter^{\circledR}$ reading score, and tongue coating and dry mouth significantly affected self-assessed halitosis severity. Conclusions: Our results suggest that tongue coating and dry mouth should be treated to improve satisfaction in halitosis patients.

• 음성과학
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• 제15권4호
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• pp.171-188
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• 2008

This study was purposed to introduce Korean Oro-motor Mechanism Screening Examination (KOMSE) and to provide the standardized scores taken from 120 normal adults aged $18{\sim}59$. KOMSE was composed of 13 items of structure, 17 items of function, 3 items of voice, and 14 items of regularity and accuracy of articulation during diadochokinesis. Additionally, maximum phonation time and diadochokinetic rates were measured. Total score of KOMSE is ranged from 0 to 200. It was significantly higher in the $50{\sim}59$ age group than in the $20{\sim}29$ age group, but was not significantly different in sex. MPT had a significant difference in sex, but no significant difference among different age groups. The rate of DDK was also had no significant difference among different age groups. However, some reducing trend in the rate of DDK was observed as age increased. KOMSE would be very helpful for SLPs to screen the abnormality of oro-motor mechanism.