• 한방안이비인후피부과학회지
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• 제23권3호
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• pp.1-10
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• 2010

Objective : Erysipelas is an acute inflammation caused by pyogenic bacteria. This mainly involves the upper part of dermis. It begins as erythematous patches with tenderness, followed by fever, headache, chills and fatigue etc. It may results in edema, obstruction of lymphatics and sepsis. So this experiment is carried out for test whether the Bojeasodok-um subtracted Scrophulariae Radix, Lasiosphaera seu Calvatia, Isatidis Radix added indigo Naturalis, Lithospermi Radix have an anti-inflammatory effect and have suppression effect on immunocyte in the state of inflammation which induced by Erysipelas. Method : Experimental animals made use of 4-5 week-age(weight 20-25g) ICR(male) mouse. In the breeding farm, the lighting time was controlled from 7:00 am till 7:00 pm, the temperature was controlled So we concluded that BS is prospected as an anti-inflammatory agent to cure inflammation induced bywithin 18-23$23^{\circ}C$ and water and food were not limited.The freezing lyophilization powder which were extracted from Bojesodok-Um divided low dose group(200mg/kg-BSL) and high dose group(500mg/kg-BSH) and after melting in water, it was orally administered to the mouse. Compared with inflammation induced group which were induced by triggering-inflammation reagent Carageenan and Zymosan and normal contrast group, we measured the edema decrement effect,macrophage and spleen cell activation. Result : 1. BS has suppress inflammatory reaction induced by Carageenan. 2. BS has suppress increasing activation of abdominal cavity macrophage in the Carageenan and Zymosan induced inflammation. 3. BS has suppress increasing activation of spleen cell in the Carageenan and Zymosan induced inflammation. Based on the above result, BS was improved its suppression effect to the inflammatory reaction through the suppression of spleen cell and macrophage activation. So we concluded that BS is prospected as an anti-inflammatory agent to cure inflammation induced by Erysipelas.

• Archives of Plastic Surgery
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• 제35권6호
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• pp.743-747
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• 2008

Purpose: Malignant changes of Marjolin's ulcer arising from chronic burn scar are rare. The majority of them are squamous cell carcinoma and basal cell carcinoma. Malignant fibrous histiocytoma is a deep seated pleomorphic sarcoma, which occurs principally as a mass of the extremities, abdominal cavity, or retroperitoneum in adults. Methods: We report a 58-year-old male patient who was admitted due to $3.5{\times}5cm$ chronic ulceration of anterior chest wall on the center of old burn scar. His scar had been occurred by boiling oil and treated with conservative treatment 45 years ago. Preoperative punch biopsy showed suspicious malignant changes and contrast enhanced chest CT showed well-defined, irregular shape enhancing lesion on anterior chest wall without intrathoracic metastasis. Results: The tumor was widely excised and defect was covered with skin graft without infection, necrosis and any other complication. The pathologic findings are compatible with malignant fibrous histiocytoma(storiform - pleomorphic type). The patient underwent 3 cycles of chemotheraphy. Although distant metastasis to the lung developed 6 months later and the patient died 9 month later, there was no local reoccurrence. Conclusion: Aggressive and early excision is needed because malignant fibrous histiocytoma has characteristics of high malignancy with a propensity for early and distant spread. Furthermore, the patient's education about disease entity and postoperative regular follow-up for local recurrence or metastasis is very important. To prevent malignancy from secondly healing burn scar, early skin graft is recommended for patients with deep second degree burn.

• Parasites, Hosts and Diseases
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• 제53권6호
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• pp.725-730
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• 2015

We report here an ectopic case of Fasciola hepatica infection confirmed by recovery of an adult worm in the mesocolon. A 56-year-old female was admitted to our hospital with discomfort and pain in the left lower quadrant of the abdomen. Abdominal CT showed 3 abscesses in the left upper quadrant, mesentery, and pelvic cavity. On surgical exploration, abscess pockets were found in the mesocolon of the sigmoid colon and transverse colon. A leaf-like worm found in the abscess pocket of the mesocolon of the left colon was diagnosed as an adult fluke of F. hepatica. Histologically, numerous eggs of F. hepatica were noted with acute and chronic granulomatous inflammations in the subserosa and pericolic adipose tissues. Conclusively, a rare case of ectopic fascioliasis has been confirmed in this study by the adult worm recovery of F. hepatica in the mesocolon.

• 대한수의학회지
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• 제44권1호
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• pp.121-124
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• 2004

Horses that have been retired from racing or imported from abroad are retired as broodmares. Whether at private farms or government institutes they are bred to stallions with the aim of improving fertility and enhancing the breed. Accidental deaths as a result of surgical or obstetrical complications lead to decreased productivity and economic losses to the horse breeding industry. Intussusception of the uterine horn is a frequent complication of the equine and bovine species, but rarely seen in other species. The most common causes are thought to be tearing of the placenta which is suspended from the uterus and ovaries and the weight of the placenta. Expulsion of the embryonic membranes is also thought to be a contributing factor. If symptoms are minor and treatment affected quickly, the problem will likely resolve itself. In more severe cases the uterus will prolapse completely. This case study was observed in a Thoroughbred broodmare. After treatment of dystocia, the broodmare could not stand up. She became dehydrated, collapsed, suffered colic and was euthanised. In this case was observed serious swelling vulva and perineal region by morphology, and there was seldom ascites and unusual view in thoracic and abdominal cavity after opening abdomen. However, intussusception of uterine horn involuted left uterine horn into the uterine body was observed.

• 한국어병학회지
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• 제16권1호
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• pp.13-21
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• 2003

The infection characteristics with scuticociliates at on-land rearing farms and hatcheries of flounder, Paralithys olivaceus was investigated during the year of 2001 by juvenile infection routes. When culture tanks for living food organisms such as chlorella, rotifer, and Artemia were searched, scuticocilates were detected both in live and dead rotifer, and at the dregs of culture tank bottoms at almost hatcheries. When rotifer infected with scuticocilates fed on fish larvae, lots of scuticocilate were inhabited at the bottom of fry rearing tanks. After feeding on scuticocilates-infected rotifer on fish larvae, first infection was detected at 10 days after bottom dwelling or 40 days old after hatching. By histopathological examination we confirmed the infection route of eyeball or brain contamination was that the ciliate worms digged through mouth and front part of the dosal fin cuticle, transferred into eyeball along the epithelium and muscle tissue, and reached finally into brain by the muscle and nerve tissue. The infection of internal organs was clarified into two routes. The first route was started from the infection at ventral and anal fin rays by the worms, and reached at the anus and rectum through the epithelium and muscle tissue. The second route was initiated from the infection at urinary organ and reached into the rectum epithelium cells, inner wall of intestine, abdominal cavity, pancreas, kidney, and pancreas. At seed production farms where fish larvae fed on scuticocilate-free rotifer, the worms were not detected not only at the food organisms culture tanks and juvenile rearing tanks but also larval flounder less than 7cm in total length.

• 한국응급구조학회지
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• 제8권1호
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• pp.33-45
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• 2004

The study is designed to develop an educational CD-Title for Basic Life Support. The study is conducted from July to December, 2002, Based on the course of program development suggested by Dick and Cray. the study followed the planning, development, education and evaluation of a program. The developed CD-Title consists of 8 parts. 1. Intro include Introduction, Adult CPR, Child CPR, Infant CPR, Adult Foreign-Body Airway Obstruction, Infant Foreign-Body Airway Obstruction, and Exercise in Menu at Right of screen. 2. Introduction consist of death process at cardiac arresst, chain of survival, introduction of CPR, respiratory & ciculatory anatomy and physiology. 3. Adult CPR consist of assessment responsiveness, activating EMS system, position victim, opening a airway, checking for breathing, rescue breathing, checking for sign of circulation, chest compression, 1 person & 2 persion adult CPR video. 4. Child & Infant CPR consist of, causes, assessment responsiveness, position victim, opening the airway, checking for breathing, rescue breathing, checking for sign of circulation, chest compression, activating EMS system, child & infant CPR video. 5. Adult Foreign-Body Airway Obstruction include assessment responsiveness, activating EMS system, position victim, opening a airway, checking for breathing, 2 rescue breathing, reopening the airway, 2 rescue breathing, finger sweep, 5 abdominal thrusts, unresponsiveness adult Foreign-Body Airway Obstruction video. 6. Infant Foreign-Body Airway Obstruction consist of, causes, assessment responsiveness, position victim, opening the airway, checking for breathing, 2 rescue breathing, reopening the airway, 2 rescue breathing, checking foreign-body object in oral cavity of victim, 5 back blow, 5 chest thsusts, activating EMS system, video. 7. 32 exercise consist of 8 Adult CPR, 12 Child & Infant CPR, 5 Adult Foreign-Body Airway Obstruction, 7 Infant Foreign-Body Airway Obstruction. Every part consist of animations to trigger students interests. This CD-Title will be useful education for first responders and lay rescuers.

• Journal of Acupuncture Research
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• 제20권1호
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• pp.159-176
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• 2003

Objective : The purpose of this study is to investigate the antioxidant activities of Alismatis Rhizoma herbal acupuncture by experimental methods. Methods : For this purpose, first, we put an emphasis in the control of enzymes of the antioxidant system in various changes inside the cell; these changes caused by the proliferation or the activation of the cell which were brought about by the handling of PMA and $TNF-{\alpha}$ into the THP-1 monocyte cell of the body each other. After that, we caused the acute oxidant symptom by the injection of AAPH into the mouse' abdominal cavity, and then applied the herbal acupuncture on S36 point(足三里), and finally, we measured the change of blood ingredient and the resistance against the activated oxygen of the red blood cell membrane, MDA, SOD, and catalase. Results : In vitro the revelation of $IL-1{\beta}$, IL-8, $TNF-{\alpha}$, NOS II and IL-6 were decreased and the revelation of IL-10, $TGF-{\beta}$, GM-CSFIL-12, GM-CSF and SOD were increased. The DNA-binding of $NF-{\kappa}B$ and AP-1 were activated and the formation of ROS in the THP-1 cell line was decreased. In vivo $IL-1{\beta}$ among producing the cytokine inside the plasma was meaningfully dwindled and the $INF-{\gamma}$ was meaningfully increased. The resistance of red blood cell membrane against the activated oxygen was meaningfully increased and the MDA formation was meaningfully dwindled, In the activation of hepatic antioxidase, the SOD was meaningfully increased. Conclusion : Alismatis Rhizoma herbal acupuncture by experimental methods has effected on the antioxidant activities.

• 대한한의학원전학회지
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• 제18권2호통권29호
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• pp.159-167
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• 2005

By comparing ‘Jing Mai(${\ulcorner}$經脈${\lrcorner}$)’ and ‘Jin Fu(${\ulcorner}$禁服${\lrcorner}$)’, we are able to see that ‘Jing Mai’ has adopted many of its aspects from ‘Jin Fu’, which also enables us to conclude that ‘Jing Mai’ was made after 'Jin Fu', with the 'Ren Ying Cun Kou Mai Fa(人迎寸口脈法)‘ being considered important. 'Jing Mai' was made relatively late, during the last days of 'Xi Han(西漢)' or early days of 'Dong Han(東漢)'. Also 'Jing Mai' was written after 'Ying Qi(${\ulcorner}$營氣${\lrcorner}$)’. ‘12 Jing Mai’ in ‘Jing Mai’ is based mainly on 'Yin Yang Shi Yi Mai Jiu Jing(${\ulcorner}$陰陽十一脈灸經${\lrcorner}$)‘ and has also referred to other meridian theories, modifying it again by theories of 'Jin Fu' and 'Ying Qi', forming the 'Jing Mai Lian Huan(經脈連環)' part. The major change in '12 Jing Mai' is that '6 Yang Jing(6陽經)' enters the abdominal and thoracic cavity, directly relating to 'Liu Fu(六腑)'. 'Ben Jing(本經)'s connection to 'Ben Zang' is referred to as 'Shu(屬)' and connection to 'Ben Zang(本臟)' is referred to as 'Lou(絡)', clarifying 'Biao Li Guan Xi(表裏關系)' inside and outslde and 'Zang Fu Xiang He(臟腑相合)' congruency. Looking at the pathological condition view of ‘Jing Mai’, the writer of 'Jing Mai Pian' has renewed it and has erased repeated symptoms of 'Suo Seng Bing(所生病)' that appears in 'Shi Dong Bing(是動病)'. If the wrong adoption of theories of previous generations are corrected and parts which do not comply with the text's original meaning and parts that posterities added are deleted, the ancient acupuncture theory preserved in this book is still a precious treasure.

• 대한한의진단학회지
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• 제20권2호
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• pp.67-75
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• 2016

Objectives There was a correlation between respiratory index and Profile of Mood States (POMS). However, no study has examined the relationship between hyperventilation and POMS. Therefore, this study showed differences in POMS subscales and respiratory patterns between hyperventilation group and normal group. Methods 20 healthy men and women were to complete Nijmegen and Korean-Profile of Mood States(K-POMS) questionnaire aimed at subjects (13 men, 12 women). By attaching a capnometer to the nasal cavity portion, end-tidal $PCO_2$ was measured. Also, marker was attached at Zhangmen, Juque, Shuifen. The movement of the marker was taken as a web cam. Statistical analysis Mann Whitney U test was used for the nonparametric methods. Results In the subscale of K-POMS were significant differences(Tension-0.001, Anger-0.007, Fatigue-0.002, Depression -0.004) between the normal group and the group with the hyperventilation. In addition, between the two groups were obtained a significant result(0.046) in the movement of the Shuifen acupoint. Conclusions Nijmegen questionnaire score is higher, the higher negative subscale scores of K-POMS. Also, differences in Nijmegen questionnaire score may help to determine the presence or absence of the abdominal breathing.

• Applied Microscopy
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• 제33권4호
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• pp.315-323
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• 2003

들풀거미(Agelena limbata) 실크 분비장치의 방적돌기와 토사관의 미세구조를 고배율의 전자현미경으로 관찰하고, 그 형태적 특성을 분석하였다. 세 쌍의 방적돌기 중에서 전 및 후방적돌기는 각각 2개의 마디로 구성되어 있는 반면, 중방적돌기는 단일 마디로 이루어져 있었으며, 특히 후방적돌기는 후방으로 매우 신장되어 있음이 관찰되었다. 방적돌기 표면에 형성된 토사관은 병상선(ampullate gland), 관상선(tubuliform gland), 이상선(pyriform gland), 포도상선(aciniform gland) 등, 4종류로 구성되어 있었다. 병상선의 토사관은 전방적돌기와 중방적돌기 표면에 각 2쌍씩이 형성되어 있었고, 암컷에서만 관찰되는 관상선의 토사관은 중방적돌기와 후방적돌기에서 관찰되었다. 또한 이상선의 토사관은 전방적돌기에서 그리고 포도상선의 토사관은 중 및 후방적돌기에서 확인되었다. 방적돌기 방적면에 형성된 토사관은 공통적으로 기저마디와 말단마디로 구성되어 있었는데, 포도상선의 토사관은 기저마디에 비해 말단마디가 매우 신전된 특징을 지니고 있음이 확인되었다.