• 아시안잔디학회지
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• 제10권2호
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• pp.117-124
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• 1996

One new cellular slime mold, Dicivostelium valenstemmun sp. n. Shim et Chang, is isolated from the fermentation layer of soils in the cool temperate forests of Surak mountain, Korea. This species has the sori and sorophore yellow-pigmented, and sparse or irregular branches. And it is characterized by tall and robust sorocarps, well-form basal disks, mucoroides-type aggregations and large spores. This species has sorophores gradually tapering from bases to tips, simple capi- tate sorophore tips and conical bases. When prostrates on the plates, it has sparsely clavate bases. Spores are considerably large, 6.8~9.9 x 3.4~5.1 $\mu$m(avg. 8.5 x 4.1 $\mu$m), L /W index l.84~2.43(avg. 2.07) without polar granules. Key words: Diccyostelium valeustemmum, Cool temperate forests, Surak mountain.

• KSBB Journal
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• 제31권4호
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• pp.312-314
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• 2016

This study was carried out to determine the antifungal activity of $SeO_2$ against pathogenic fungus, Candida albicans. Concentration-dependent Inhibitory activity of $SeO_2$ against C. albicans was shown. When $400{\mu}g/disc$ of $SeO_2$ was tested, the inhibition size ranged from 20.7 to 26.8 mm (avg. 23.4 mm). MIC values of $SeO_2$ against cell growth of C. albicans ranged from 50 to $100{\mu}g/mL$ (avg. $70{\mu}g/mL$). These results could be applied to antibiotics-resistant C. albicans and other pathogenic fungi.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 하계학술대회 논문집 D
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• pp.2450-2452
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• 2004

Map building is essential to a mobile robot navigation system. Localization and path planning methods depend on map building strategies. A topological map is commonly constructed using the GVG(Generalized Voronoi Graph). The advantage of the GVG based topological map is compactness. But the GVG method have many difficulties because it consists of collision-free path. In this paper, we proposed an extended map building method, the AVG (Areal Voronoi Graph) based topological map. The AVG based topological map consists of collision-free area. This feature can improve map building, localization and path planning performance.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.274-279
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• 2001

Creep-fatigue crack growth behavior was experimentally measured particularly when a crack was located in the heat affected region of 1Cr-0.5Mo steel. Load hold times of the tests for trapezoidal fatigue waveshapes were varied among 0, 30, 300 and 3,600 seconds. Time-dependent crack growth rates were characterized by the $C_t$-parameter. It was found that the crack growth rates were the highest when the crack path was located along the fine-grained heat affected zone(FGHAZ). Cracks located in other heat affected regions had a tendency to change the crack path eventually to FGHAZ. Creep-fatigue crack growth law of the studied case is suggested in terms of $(da/dt)_{avg}$ vs. $(C_t)_{avg}$ for residual life assessment.

• Journal of Microbiology and Biotechnology
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• 제15권4호
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• pp.855-858
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• 2005

The bioavailability of Ca is currently one of the most important topics in nutrition research and is correlated with gastrointestinal solubility. Thus, to increase the solubility of calcium, this study was undertaken to examine the effect of $\gamma$-PGA on intestinal Ca solubility. The calcium solubility increased when the amount of $\gamma$-PGA was increased, due to the inhibition of the formation of an insoluble Ca complex with phosphate. Therefore, when $\gamma$-PGA-500 (avg. MW 5,000 kDa) was added at 0.5 mg/ml, $75\%$ of the total Ca was soluble. The amount of soluble Ca uptake in the small intestine was investigated using Balb/c mice as an animal model system. The soluble Ca uptake in the mice orally administered with $\gamma$-PGA-500 (avg. MW 5,000 kDa) was significantly higher than that in the $\gamma$-PGA-l00 (avg. MW 1,000 kDa)-administered mice (P<0.05). Accordingly, these results strongly support the notion that the molecular size of $\gamma$-PGA is correlated with Ca solubility. The effects of other factors, such as casein phosphopeptide and vitamin D, on intestinal Ca absorption have also previously been investigated. Therefore, it is hoped that the present observations will help clarify the role of $\gamma$-PGA in Ca solubility and its industrial application as an additive.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제30권5호
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• pp.437-446
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• 2008

Electroglottography (EGG) is a simple and non-invasive technique for analyzing the vibratory patterns of the vocal folds by detecting impedance changes across the larynx. An abnormal electroglottogram is shown in patients who have a dysphagia associated with neuromuscular disorder. Electroglottography offers reliable informations for diagnosis of swallowing disorder and gives quantitative datas. The purpose of this study is to provide the normal value of electroglottography in normal adults. We took electroglottograms of 80 adults who have no problem in swallowing and utterance. EGG data were analyzed to find out the value of Pitch, Jitter and Closed quotient with a commercially available software. There were significant differences between a usual voice and loud voice in 3 measures on the EGG signalmean pitch, Avg. jitter, mean quotient. To get a proper electroglottography, phonation of a usual voice was better than a loud voice. Four measurements- S.D pitch, Avg. Jitter, Mean closed quotient, S.D closed quotient- were independent of sex for adult. Three measurements- Mean pitch, S.D pitch, Mean closed quotient - were independent of age for adult aged twenties to fifties. The Avg. Jitter of twenties appeared to be lower than those of forties and fifties. The S.D closed quotient of twenties appeared to be lower than those of thirties, forties and fifties.

• International journal of advanced smart convergence
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• 제5권3호
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• pp.56-60
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• 2016

Body physical technique is to pursuit the dynamic motion by the physical index(PI) and sensory index(SI) on the physical body function. Function of the physical body by the motor condition is organized the dynamic physical system. For the physical motion of signal, we is defined a runout value of the body function by the physical index on the dynamic state. The concept of body physical index was identified the reference of physical index and sensory index by the body technique. As to detect a variation of the body physical technique-runout physical index(BPT-RPI) of the maximum and average and minimum in terms of physical motion, and the dynamic sensory value that was a runout function of the vision variation of the $Vi-{\xi}_{MAX-AVG-MIN}$ with $2.53{\pm}4.85$ units, that was a runout function of the vestibular variation of the $Ve-{\xi}_{MAX-AVG-MIN}$ with ($-0.69{\pm}2.32$)units, that was a runout function of the somatosensory variation of the $So-{\xi}_{MAX-AVG-MIN}$ with ($-1.43{\pm}-1.36$) units. The dynamic physical motion will be to confirm at the variable function of the runout motion for the body function values of dynamic physical index on the BPT-RPI that was identified an evaluation of the physical sensory function by the dynamic physical system. Runout body system was mentioned of a physical body situation by the mild moving and was refer a runout data of dynamic physical nervous index.

• International Journal of Advanced Culture Technology
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• 제4권3호
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• pp.56-61
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• 2016

Central motion techniques are to mention the central-motion by the limpness motion function and limpness sensory unit function on the body. Central body motion is consisted of the limpness central function by the central body system. To evaluate the signal of central body motion, we are investigated a limpness value of the central function by the central body function on the static state. The concept of limpness motion function was checked the reference of limpness motion signal and limpness sensory signal by the central motion body. For assessment on the limpness sensory variation of the maximum and average in terms of central motion from the static function, and limpness value that was a limpness value of the vision condition of the Vi-${\lambda}_{MAX-AVG}$ with $8.71{\pm}-3.2units$, that was a limpness value of the vestibular condition of the Ve-${\lambda}_{MAX-AVG}$ with $3.05{\pm}-6.52units$, that was a limpness value of the somatosensory condition of the So-${\lambda}_{MAX-AVG}$ with $2.4{\pm}1.9units$. The static sensory motion was made mention of check out at the condition of the limpness sensory unit motion for the comparable values of limpness central motion that was expressed the analysis capacity by the limpness nerve system. Limpness sensory system will be to propose of the minute motion by static central motion situation and was to imply a limpness motion data of static body sensory function.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2005년도 총회 및 춘계학술발표회
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• pp.17-19
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• 2005

This study is for geochemical relationships between ginseng and soil from three representative soil types from Keumsan, shale, phyllite and granite. In the weathered soils(avg.), shale area is high in the most of element, but low in the granite area. In the field soils(avg.), the shale area is mainly high, but low in the granite area and comparing with ages, most of elements are high in the 2 year soils, but low in the 4 year soils. In the host rocks(avg.), high average element contents are shown in the phyllite and shale areas. In the ginsengs, differences of the element contents with ages are not clear, but show high element contents in the 2 year ginsengs of the shale and phyllite areas, and low contents in the 4 year ginsengs of the granite area. In the relative ratios(weathered soil/field soil), most of elements from the shale area are high, above 1, suggesting high element contents in the weathered soils of the shale area relative to the granite and phyllite areas. In the relative ratios(weathered soil/host rock), most of elements Ewe above 1, suggesting the high element contents in the weathered soils relative to the host rocks. Relative ratios (soil/ginseng) of the element contents are generally several times to ten times. Among the ginsengs of different ages with the same area, the relative ratios are small in the Cu and Zn contents. Regardless of the areas, big differences of the relative ratios are found in the Co and small differences are in the Cu and Zn, which suggest that differences between soils and ginsengs are big in the Co contents and small in the Cu and Zn contents. Regardless of the ages, differences among relative ratios are small in granite area relative to the shale. area, which suggest more similarity of the granite soils with ginsengsrelativetotheshalearea.

• The Korean Journal of Physiology and Pharmacology
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• 제23권4호
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• pp.231-236
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• 2019

In drug discovery or preclinical stages of development, potency parameters such as $IC_{50}$, $K_i$, or $K_d$ in vitro have been routinely used to predict the parameters of efficacious exposure (AUC, $C_{min}$, etc.) in humans. However, to our knowledge, the fundamental assumption that the potency in vitro is correlated with the efficacious concentration in vivo in humans has not been investigated extensively. Thus, the present review examined this assumption by comparing a wide range of published pharmacokinetic (PK) and potency data. If the drug potency in vitro and its in vivo effectiveness in humans are well correlated, the steady-state average unbound concentrations in humans [$C_{u_-ss.avg}=f_u{\cdot}F{\cdot}Dose/(CL{\cdot}{\tau})=f_u{\cdot}AUCss/{\tau}$] after treatment with approved dosage regimens should be higher than, or at least comparable to, the potency parameters assessed in vitro. We reviewed the ratios of $C_{u_-ss.avg}$/potency in vitro for a total of 54 drug entities (13 major therapeutic classes) using the dosage, PK, and in vitro potency reported in the published literature. For 54 drugs, the $C_{u_-ss.avg}$/in vitro potency ratios were < 1 for 38 (69%) and < 0.1 for 22 (34%) drugs. When the ratios were plotted against $f_u$ (unbound fraction), "ratio < 1" was predominant for drugs with high protein binding (90% of drugs with $f_u{\leq}5%$; i.e., 28 of 31 drugs). Thus, predicting the in vivo efficacious unbound concentrations in humans using only in vitro potency data and $f_u$ should be avoided, especially for molecules with high protein binding.