• Proceedings of the Korean Society of Computer Information Conference
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• 2009.01a
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• pp.113-116
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• 2009

현재 우리의 7차 교육과정에서 교육의 보조 도구로써 교실에서 사용될 수 있는 것은 별로 많지 않다. 그래서 AvaLab은 이 시점에서 좋은 도구가 될 수 있다. AvaLab은 컴퓨터에 익숙하지 않은 학생을 위한 GUI 프로그래밍 도구이며, 현재의 교육 과정에서 필요로 하는 창의성을 키우기 위한 한 도구로써 교실에서 사용될 수 있다. 사용하려면, 먼저 학습자는 프로그래밍 아이디어를 생각하고, 아이콘 기반의 AvaLab을 통하여 프로그래밍한다. 프로그래밍 후에 학습자는 로봇의 결과를 생각하고 토론할 수 있다. 만약 그 결과가 정확화지 않다면, 로봇은 피드백을 보일 젓이다. 그러므로, AvaLab은 초보자를 위한 도구이며, 7차 교육과정에 적합한 도구이다. AvaLab의 특징 중 하나는 아이콘 기반의 흐름도 모델로 구성되어 있다는 것과 학습자는 입력과 출력 센스를 갖는 로봇을 이용해 실습할 수 있다는 것이다.

• Korean Journal of Microbiology
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• v.24 no.2
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• pp.86-90
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• 1986

The DNA methylated by Hpa II methylase was not cleaved by Sma, I, Ava I and Nae I endonucleases. This experimental data could be interpreted as strong evidences that Sma I, Ava I and Nae I methylases which yet to be isolated would methylate on the inmost cytosine nucleotide within their hexameric recognition sequences. The facts that Sma I, Ava I and Nae I endonucleases can not cleave the DNA methylated by Hpa II methylase are the valuable informations for protecting DNAs upon cleavage reactions by Sma I, Ava I and NAe I endonucleases especially for cDNA insertion experiments into vector DNAs using Sma I, Ava I and Nae I oligonucleotide linkers. In the case of Xma I endonuclease, partially cleaved DNA fragments were observed although the reaction rate was greatly decreased. This result implies that the methylation site of Xma I methylase which yet to be isolated would not be the same as that of Hpa II methylase in Xma I sequence.

• Journal of the Korean Data and Information Science Society
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• v.27 no.6
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• pp.1453-1463
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• 2016

The most useful financial risk measure may be VaR (Value at Risk) which estimates the maximum loss amount statistically. The VaR tends to be estimated in many industries by using transformed univariate risk including variance-covariance matrix and a specific portfolio. Hong et al. (2016) are defined the Vector at Risk based on the multivariate quantile vector. When a specific portfolio is given, one point among Vector at Risk is founded as the best VaR which is called as an alternative VaR (AVaR). In this work, AVaRs have been investigated for multivariate normal distributions with many kinds of variance-covariance matrix and various portfolio weight vectors, and compared with VaRs. It has been found that the AVaR has smaller values than VaR. Some properties of AVaR are derived and discussed with these characteristics.

• Parasites, Hosts and Diseases
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• v.56 no.2
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• pp.105-112
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• 2018

Blastocystis is an enteric Straminopile in tropical, subtropical and developing countries. Metronidazole has been a chemotheraputic for blastocystosis. Failures in its regimens were reported and necessitate new studies searching for alternative therapeutic agents. Aim of current study is to investigate potential effects of Atorvastatin (AVA) compared to the conventional chemotherapeutic MTZ in experimentally Blastocystis-infected mice. Anti-Blastocystis efficacy of AVA was evaluated parasitologically, histopathologically and by transmission electron microscopy using MTZ (10 mg/kg) as a control. Therapeutic efficacy of AVA were apparently dose-dependent. Regimens of AVA (20 and 40 mg/kg) proved effective against Blastocystis infections with highreduction in Blastocystis shedding (93.4-97.9%) compared to MTZ (79.3%). The highest reductions (98.1% and 99.4%)were recorded in groups of combination treatments AVA 20-40 mg/kg and MTZ 10 mg/kg. Blastocystis was nearly eradicated by the 20th day post infection. Genotype analysis revealed that genotype I was most susceptible, genotype III was less. Histopathologic and ultrastructural studies revealed apoptotic changes in Blastocystis and significant improvement of intestinal histopathological changes more remarkable in combinational therapy groups. Thus, the present study offers AVA as a potential candidate for Blastocystis therapy combined with MTZ.

• Korean Journal of Radiology
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• v.22 no.8
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• pp.1266-1278
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• 2021

Objective: We aimed to compare the aortic valve area (AVA) calculated using fast high-resolution three-dimensional (3D) magnetic resonance (MR) image acquisition with that of the conventional two-dimensional (2D) cine MR technique. Materials and Methods: We included 139 consecutive patients (mean age ± standard deviation [SD], 68.5 ± 9.4 years) with aortic valvular stenosis (AS) and 21 asymptomatic controls (52.3 ± 14.2 years). High-resolution T2-prepared 3D steady-state free precession (SSFP) images (2.0 mm slice thickness, 10 contiguous slices) for 3D planimetry (3DP) were acquired with a single breath hold during mid-systole. 2D SSFP cine MR images (6.0 mm slice thickness) for 2D planimetry (2DP) were also obtained at three aortic valve levels. The calculations for the effective AVA based on the MR images were compared with the transthoracic echocardiographic (TTE) measurements using the continuity equation. Results: The mean AVA ± SD derived by 3DP, 2DP, and TTE in the AS group were 0.81 ± 0.26 cm², 0.82 ± 0.34 cm², and 0.80 ± 0.26 cm², respectively (p = 0.366). The intra-observer agreement was higher for 3DP than 2DP in one observer: intraclass correlation coefficient (ICC) of 0.95 (95% confidence interval [CI], 0.94-0.97) and 0.87 (95% CI, 0.82-0.91), respectively, for observer 1 and 0.97 (95% CI, 0.96-0.98) and 0.98 (95% CI, 0.97-0.99), respectively, for observer 2. Inter-observer agreement was similar between 3DP and 2DP, with the ICC of 0.92 (95% CI, 0.89-0.94) and 0.91 (95% CI, 0.88-0.93), respectively. 3DP-derived AVA showed a slightly higher agreement with AVA measured by TTE than the 2DP-derived AVA, with the ICC of 0.87 (95% CI, 0.82-0.91) vs. 0.85 (95% CI, 0.79-0.89). Conclusion: High-resolution 3D MR image acquisition, with single-breath-hold SSFP sequences, gave AVA measurement with low observer variability that correlated highly with those obtained by TTE.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.9
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• pp.119-129
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• 2019

The purpose of this paper is to study the meaning of Rem Koolhaas's works focused on Villa Dall'Ava. This House which offers a fine example of the early architectural concepts of Rem Koolhaas was completed in 1991, 7 year earlier than the Maison Bordeaux and also this work is the only one house constructed in Paris. Rem Koolhaas, one of the most influential architects representing contemporary architecture in these days is interpreted so diversely as new constructivism, deconstruction and new scientism etc. The relationship between Modernism architecture and the architecture of Rem Koolhaas is supposed in various point of view in recent studies. Although the leading background on which the architectural inclination of Rem Koolhaas is de-constructivism, various interviews, editorials and other perspectives give clue that Rem Koolhaas was influenced by Modernism. His architectural concept is connected with the architectural principles of Le Corbusier: 'Five Points of a New Architecture' and 'Dom-ino system', which are especially applied a lot to Villa Dall'Ava in the modified form. This study is to research the architectural characteristics of Villa Dall'Ava by analyzing the layout, plan, elevation, section and structure, which revealed the architectural connectivity between the concept of Rem Koolhaas and the architectural principles of Le Corbusier which had a great effects on architectural history and became a fundamental elements for the change into the modern architecture. In practice, the architectural work of Rem Koolhaas remind the architectural principles of Le Corbusier. This research appraises each points of 'Five Points of a New Architecture' in regarding with Villa Dall'Ava whose study will be important to find the meaning of the works and ideas of Rem Koolhaas.

• Journal of the Korean Society of Clothing and Textiles
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• v.23 no.2
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• pp.242-249
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• 1999

The purpose of this study was to investigate two different kinds of socks on physiological responses at an ambient temperature of 35$\pm$1$^{\circ}C$ and relative humidity of 50$\pm$5% Five healthy women wearing normal socks or toes socks participated as the subjects. Rectal temperature skin temperatures sweat rate blood pressure pulse rate and questionnaire wee measured. Rectal temperature skin temperature sweat rate blood pressure pulse rate and questionnaire were measured. Rectal temperature and mean skin temperature were lower after exercise at wearing toes socks . Sweat rate was higher at wearing normal socks and blood pressure and pulse rate were tend to higher at wearing toes socks. Thermal comfort temperature sensation and humidity sensation were better wearing toes socks. Thermal comfort temperature sensation and humidity sensation were better wearing toes socks than wearing normal socks but wearing comfort was better at wearing normal socks. These results will be discussed form the viewpoint of thermoregulation AVA(Arterio venous Anastomosis) and count current heat exchange.

• Korean Journal of Microbiology
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• v.29 no.4
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• pp.226-229
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• 1991

In our laboratory a R plasmid pKU10 was isolated from Pseudomonas and its characteristics were investigated. In this study, as a basic work to improve its utility as a cloning vehicle, restriction patterns of pKU10 were analyzed for other various restriction enzymes in addition to restriction evdonucleases previously examined. As a result, pKU10 DNA has two cleavage sites for ClaI and HpaI, and three sites for AvaI. The restriction map of pKU10 was supplemented with AvaI, ClaI, and HpaI. From the result of this experiment, the usefulness of PKU10 as a cloning vector in Pseudomonas will be enhanced by constructions of mini-plasmid or hybrid plasmids.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.24 no.1
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• pp.47-54
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• 2016

Global aviation is projected to grow in demand by an annual average of 4.1% between 2014 and 2034. It can be said that environmental impact from aviation will therefore be expected to increase on a similar scale. As regards civil aviation emissions, the sector contributes between 2~3% to International aviation GHG emissions. In the European Union(EU), aviation emissions account for about 3% of the EU's total green house gas emissions, of which a majority are said to come from international flights. In terms of traffic volume in 2013, Korea's international aviation industry 11th with regard to passengers and 3rd with regard to cargo, attaining the overall rank of 5th in the world. GHG emissions has been increasing steadily over the last 4 years, averaging 3.9 percent a year, due to the growth of low cost carriers and the increased demand for air transportations. As for aviation in Korea, there are a number of means intended to attain the Government's emission control objective in an efficient manner, such as AVA (Agreement of Voluntary Activity), TMS (Target Management System) and ETS (Emission Trading Scheme). In addition, the Government intends to better adapt to ICAO's Global MBM(Market-based Measures) that will come into performance on Year 2020. In the study, we focused on GHG mitigation measures that is fulfilling the AVA, TMS, ETS in the Government and suggest the effective measures to reduction the aviation GHG emissions.

• Journal of Aquaculture
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• v.17 no.1
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• pp.1-7
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• 2004

A rainbow trout uncoupling protein 3 (UCP3) cDNA clone, encoding a 310 amino acid protein, was cloned and sequenced from a liver cDNA library. Two different splice variants designated UCP3-vl and UCP3-v2, were identified through liver cDNA library screening using rainbow trout UCP3 cDNA clone as a probe. UCP3-vl has 3 insertions in the UCP3 cDNA: the first insertion (133 bp), the second (141 bp), and the third (370 bp) were located 126 bp, 334 bp and 532 bp downstream from the start codon, respectively. UCP3-v2 contained a single insertion, identical in sequence and location to the second insertion of UCP3-vl. UCP3, a mitochondrial protein, functions to modulate the efficiency of oxidative phosphorylation. UCP3 has been detected from heart, testis, spinal cord, eye, retina, colon, muscle, brown adipose tissue and white adipose tissue in mammalian animals. Human and rodent UCP3s are highly expressed in skeletal muscle and brown adipose tissue, while they show weak expression of UCP3 in heart and white adipose tissue. In contrast to mammalian studies, RT-PCR and Southern blot analysis of the rainbow trout demonstrated that UCP3 is strongly expressed in liver and heart. UCP3, UCP3-vl, and UCP3-v2 all contain an Ava III short interspersed element (SINE), located in the 3'untraslated region (UTR). PCR using primers from the Ava III SINE and the UCP3 3'UTR region indicates that the UCP3 cDNA is structurally conserved among salmonids and that these primers may be useful for salmonid species genotyping.