• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1813-1816
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• 2015

Background: The aim of this study was to research the importance of the neutrophil to lymphocyte ratio (NLR) in prediction of PSA recurrence after radical prostatectomy, which has not been reported so far. Materials and Methods: The data of 175 patients who were diagnosed with localised prostate cancer and underwent retropubic radical prostatectomy was retrospectively examined. Patient pre-operative hemogram parameters of neutrophil count, lymphocyte count and NLR were assessed. The patients whose PSAs were too low to measure after radical prostatectomy in their follow-ups, and then had PSAs of 0,2 ng/mL were considered as patients with PSA recurrence. Patients with recurrence made up Group A and patients without recurrence made up Group B. Results: In terms of the power of NLR value in distinguishing recurrence, the area under OCC was statistically significant (p<0.001) .The value of 2.494 for NLR was found to be a cut-off value which can be used in order to distinguish recurrence according to Youden index. According to this, patients with a higher NLR value than 2.494 had higher rates of PSA recurrence with 89.7% sensitivity and 92.6% specificity. Conclusions: There are certain parameters used in order to predict recurrence with today's literature data.We think that because NLR is easy to use in clinics and inexpensive, and also has high sensitivity and specificity values, it has the potential to be one of the parameters used in order to predict biochemical recurrence in future.

• The Journal of Advanced Prosthodontics
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• v.4 no.2
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• pp.109-115
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• 2012

PURPOSE. The purpose of this clinical study was to evaluate the frequency and type of prosthetic complications in relation to type and properties of removable dentures and to investigate the influence of these complications and several data about the existing dentures on patient satisfaction. MATERIALS AND METHODS. Ninety nine patients (44 males and 55 females) wearing removable dentures have been included in the study. The complications of the patients were recorded; patient satisfaction was determined with a Visual Analog Scale (VAS) and the relationship of complications and patient satisfaction with several data about the dentures such as denture age, type of denture, centric relation and vertical dimension was investigated. Kruskal Wallis, Mann Whitney U and Chi square tests were used for statistical analyses. The results were evaluated statistically at a significance level of $P$ <.05. RESULTS. Need for addition of artificial teeth for dentures with correct centric relations was found to be significantly lower than dentures with wrong centric relations ($P$ <.01). Loss of retention, ulcerations and high vertical dimension affected the VAS chewing ability scores negatively and ulcerations affected the VAS phonation scores negatively ($P$ <.05). CONCLUSION. Considering the results of this study, it can be concluded that loss of retention, ulcerations and high vertical dimension caused patient dissatisfaction. Additionally, dentures with wrong centric relations caused need for addition of artificial teeth.

• Journal of the KSME
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• v.44 no.2
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• pp.23-25
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• 2004

이 글에서는 CFD의 효율적인 적용 및 사용을 통하여 제품의 설계와 생산 공정의 최적화가 어떻게 구현될 수 있으며 CFD를 이용한 최적화 과정 에서 걸림돌이 되는 것들로는 어떤 요소들이 있는 지 관하여 다루고자 한다. CFD와 같은 CAE tool 을 이용한 설계 과정의 최적화는 최신의 기술을 장착하고 있는 상업용 CFD 소프트웨어들에 의하여 가능하며 이들 코드들에 관한 특성들도 이 글 에셔 취급하고자 한다. 잘 알려진 바와 같이 제품 의 초기 개념 설계 단계에서부터 계획 및 상세설계에 이르기까지 각 단계에서 최적의 조건을 구하 기 위해서는 주어진 구속조건에서 변수들에 관한 반복적인 시뮬레이션이 수행되어야 한다. 이러한 과정에서 각각의 조건에 관한 시뮬레이션 과정이 시간이 비교적 많이 소요되는 수동적인 방법으로 이루어질 경우 최적화는 불가능하다. 즉 각 설계 변수의 최적화 조건을 구하기 위하여 CAE과정에 서 자동화(automation)은 필수적일 것이다. 전산 유체 역학(computational fluid dynamics)은 지난 30여 년 동안 다양한 유체유통 및 열전달 분야에서 사용되어져 오고 있는 시뮬레이션 기술이 다. 산업분야에서 CFD에 대한 요구가 증대됨에 따라 20여 년 전부터 상업용 CFD 코드가 등장하기 시작하였으며 근래 들어서는 약 80여 종류의 상업용 CFD 코드가 자동차, 전자, 화공, 건설, 조 선, 제강과 같은 여러가지 종류의 산업분야에서 이용되어 오고 있다 하지만 상업용 CFD 코드가 고가인 이유 때문에 비교적 풍부한 예산이 확보된 대기업 및 국책 연구소 중심으로 이에 관한 사용 자 층은 매우 제한적이었다. 아울러 사용상의 난 점 때문에 CFD를 전공한 전문가 집단 위주로 사 용되어 오고 있다. 이런 측면에서 볼 때 설계 분야 에 종사하는 엔지니어들이 CFD를 이용하여 설계를 하는 데는 상당한 괴리감이 존재하게 된다. 전 통적으로 CFD와 같은 해석은 설계에 대한 타당서 검증의 목적으로 설계 사이클에서 맨 마지막에 수행되어져 왔기 때문에 CFD가 설계에 직접적인 도움을 주지 못하고 보조의 역할밖에 하지 못하는 수몽척인 도구로 여겨져 왔다. 이려한 설계 경향 은 CFD가 설계 과정에서 요구하는 시간 내에 시뮬레이션이 불가능하기 때문에 나타난 현상이다 상기에서 언급된 문제점인 시abf레이션의 시간 단 축은 설계 부서 에서 사용되는 CAD 도구와 CFD와 같은 CAE tool을 적절하게 접목함으로써 (integration) 가능할 것이다. 이후에서는 CFD의 시뮬레이션 과정을 자동화하기 위하여 고려되어 야 할 요소들에는 어떤 것들이 있는지에 관하여 알아보고자 한다.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.5 no.3
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• pp.213-220
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• 2007

Appropriate numerical models for the simulation of off-gas flow in hot area of the vitrification plant have been developed in this study. The models have been applied to analyze the effect of design parameters of real plant and numerical analyses have been performed for CCM(Cold Crucible Melter), pipe cooler and HTF(High Temperature Filter). At first, the effect of excess oxygen and the ratio of oxygen distribution on combustion characteristics in the CCM has been studied. Next, solidification behavior of radio nuclide in the pipe cooler has been numerically modeled and scrutinized. Finally, flow pattern in accordance with the location of off-gas entrance of the HTF has been compared.

• Computers and Concrete
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• v.12 no.2
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• pp.169-186
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• 2013

The aim of this paper is to determine the effect of soil-structure interaction and time dependent material properties on behavior of concrete box-girder highway bridges. Two different finite element analyses, one stage and construction stage, have been carried out on Komurhan Bridge between Elazi$\breve{g}$ and Malatya province of Turkey, over Fırat River. The one stage analysis assume that structure was built in a second and material properties of structure not change under different loads and site conditions during time. However, construction stage analysis considers that construction time and time dependent material properties. The main and side spans of bridge are 135 m and 76 m, respectively. The bridge had been constructed in 3 years between 1983 and 1986 by balanced cantilever construction method. The parameters of soil-structure interaction (SSI), time dependent material properties and construction method are taken into consideration in the construction stage analysis while SSI is single parameter taking into consideration in the one stage analysis. The 3D finite element model of bridge is created the commercial program of SAP2000. Time dependent material properties are elasticity modulus, creep and shrinkage for concrete and relaxation for steel. Soft, medium, and firm soils are selected for evaluating SSI in both analyses. The results of two different finite element analyses are compared with each other. It is seen that both construction stage and SSI have a remarkable effect on the structural behavior of the bridge.

• Steel and Composite Structures
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• v.23 no.3
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• pp.273-283
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• 2017

In this paper, it is aimed to present a detail investigation related to structural behavior of laterally unrestrained steel cantilever roof of tribune with slender cross section. The structure is located in Tutak town in $A{\breve{g}}r{{\i}}$ and collapsed on October 25, 2015 at eastern part of Turkey is considered as a case study. This mild sloped roof structure was built from a variable I beam, and supported on steel columns of 5.5 m height covering totally $240m^2$ closed area in plan. The roof of tribune collapsed completely without any indication during first snowfall after construction at midnight a winter day, fortunately before the opening hours. The meteorological records and observations of local persons are combined together to estimate the intensity of snow load in the region and it is compared with the code specified values. Also, the wide/thickness and height/thickness ratios for flange and web are evaluated according to the design codes. Three dimensional finite element model of the existing steel tribune roof is generated considering project drawings and site investigations using commercially available software ANSYS. The displacements, principal stresses and strains along to the cantilever length and column height are given as contour diagrams and graph format. In addition to site investigation, the numerical and analytical works conducted in this study indicate that the unequivocal reasons of the collapse are overloading action of snow load intensity, some mistakes made in the design of steel cantilever beams, insufficient strength and rigidity of the main structural elements, and construction workmanship errors.

• Earthquakes and Structures
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• v.6 no.4
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• pp.375-392
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• 2014

Time history analyses have been preferred commonly in earthquake engineering area to determine earthquake performances of structures in recent years. Advances in computer technology and structural analysis have led to common usage of time history analyses. Eurocode 8 allows the use of real earthquake records as an input for linear and nonlinear time history analyses of structures. However, real earthquake records with the desired characteristics sometimes may not be found, for example depending on soil classes, in this case artificial and synthetic earthquake records can be used for seismic analyses rather than real records. Selected earthquake records should be scaled to a code design spectrum to reduce record to record variability in structural responses of considered structures. So, scaling of earthquake records is one of the most important procedures of time history analyses. In this paper, four real earthquake records are scaled to Eurocode 8 design spectrums by using SESCAP (Selection and Scaling Program) based on time domain scaling method and developed by using MATLAB, GUI software, and then scaled and real earthquake records are used for linear time history analyses of a six-storied building. This building is modeled as spatial by SAP2000 software. The objectives of this study are to put basic procedures and criteria of selecting and scaling earthquake records in a nutshell, and to compare the effects of scaled earthquake records on structural response with the effects of real earthquake records on structural response in terms of record to record variability of structural response. Seismic analysis results of building show that record to record variability of structural response caused by scaled earthquake records are fewer than ones caused by real earthquake records.

• Earthquakes and Structures
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• v.7 no.4
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• pp.511-525
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• 2014

The main object of this study is to determine and compare the structural behavior of base isolated long span highway bridge, $G\ddot{u}lburnu$ Highway Bridge, using single concave friction pendulum (SCFP) and triple concave friction pendulum (TCFP). The bridge is seismically isolated in the design phase to increase the main period and reduce the horizontal forces with moments using SCFP bearings. In the content of the paper, firstly three dimensional finite element model (FEM) of the bridge is constituted using project drawings by SAP2000 software. The dynamic characteristics such as natural frequencies and periods, and the structural response such as displacements, axial forces, shear forces and torsional moments are attained from the modal and dynamic analyses. After, FEM of the bridge is updated using TCFP and the analyses are performed. At the end of the study, the dynamic characteristics and internal forces are compared with each other to extract the TCFP effect. To emphasize the base isolation effect, the non-isolated structural analysis results are added to graphics. The predominant frequencies of bridge non-isolated, isolated with SCFP and isolated with TCFP conditions decreased from 0.849Hz to 0.497Hz and 0.338Hz, respectively. The maximum vertical displacements are obtained as 57cm, 54cm and 44cm for non-isolated, isolated with SCFP and isolated with TCFP conditions, respectively. The maximum vertical displacement reduction between isolated with TCFP bearing and isolated with SCFP bearing bridge is %23. Maximum axial forces are obtained as 60619kN, 18728kN and 7382kN, maximum shear forces are obtained as 23408kN, 17913kN and 16249kN and maximum torsional moments are obtained as 24020kNm, 7619kNm and 3840kNm for non-isolated, isolated with SCFP and isolated with TCFP conditions, respectively.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7463-7466
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• 2015

Aims: To analyse the predictors of recurrence, disease free survival and overall survival in cases with endometrial cancer. Materials and Methods: A total of 152 women diagnosed with endometrial cancer were screened using a prospectively collected database including age, smoking history, menopausal status, body mass index, CA125, systemic disorders, tumor histology, tumor grade, lymphovascular space invasion, tumor diameter, cervical involvement, myometrial invasion, adnexal metastases, positive cytology, serosal involvement, other pelvic metastases, type of surgery, fertility sparing approach to assess their ability to predict recurrence, disease free survival and overall survival. Results: In ROC analyses tumor diameter was a significant predictor of recurrence (AUC:0.771, P<0.001). The optimal cut off value was 3.75 with 82% sensitivity and 63% specificity. In correlation analyses tumor grade (r=0.267, p=0.001), tumor diameter (r=0.297, p<0.001) and the serosal involvement (r=0.464, p<0.001) were found to significantly correlate with the recurrence. In Cox regression analyses when some different combinations of variables included in the model which are found to be significantly associated with the presence of recurrence, tumor diameter was found to be a significant confounder for disease free survival (OR=1.2(95 CI,1.016-1.394, P=0.031). On Cox regression for overall survival only serosal involvement was found to be a significant predictor (OR=20.8 (95 % CI 2.4-179.2, P=0.006). In univariate analysis of tumor diameter > 3.75 cm and the recurrence, there was 14 (21.9 %) cases with recurrence in group with high tumor diameter where as only 3 (3.4 %) cases group with smaller tumor size (Odds ratio:7.9 (95 %CI 2.2-28.9, p<0.001). Conclusions: Although most of the significantly correlated variables are part of the FIGO staging, tumor diameter was also found to be predictor for recurrence with higher values than generally accepted.

• Journal of the Korean Society for Marine Environment & Energy
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• v.12 no.1
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• pp.9-14
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• 2009

A numerical investigation was performed based on the Reynolds-Averaged Navier-Stokes(RANS) equations for the two-dimensional unsteady flow around a vertical axis turbine(VAT) with three or four blades. VAT is one of the promising devices for tidal current energy conversion. The geometry of the turbine blade was $NACA65_3$-018 airfoil, for which CFD analysis using Fluent was carried out at several angles of attack and the results were compared with the corresponding experimental data for validation and calibration. Then CFD simulations were carried out for the whole vertical axis turbine with a two-dimensional setup. The CFD simulation demonstrated the usefulness of the method to study the typical unsteady flows around VATs and the results showed that the optimum turbine efficiency could be achieved for carefully selected combinations of the number of blade and Tip-Speed Ratio(TSR).