• Geomechanics and Engineering
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• v.8 no.4
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• pp.615-630
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• 2015

The use of helical anchors has been extensively beyond their traditional use in the electrical power industry in recent years. They are commonly used in more traditional civil engineering infrastructure applications so that the advantages of rapid installation and immediate loading capability. The majority of the research has been directed toward the tensile uplift behaviour of single anchors (only one plate) by far. However, anchors commonly have more than one plate. Moreover, no thorough numerical and experimental analyses have been performed to determine the ultimate pullout loads of multi-plate anchors. The understanding of behavior of these anchors is unsatisfactory and the existing design methods have shown to be largely inappropriate and inadequate for a framework adopted by engineers. So, a better understanding of helical anchor behavior will lead to increased confidence in design, a wider acceptance as a foundation alternative, and more economic and safer designs. The main aim of this research is to use numerical modeling techniques to better understand multi-plate helical anchor foundation behavior in soft clay soils. Experimental and numerical investigations into the uplift capacity of helical anchor in soft clay have been conducted in this study. A total of 6 laboratory tests were carried out using helical anchor plate with a diameter of 0.05 m. The results of physical and computational studies investigating the uplift response of helical anchors in soft clay show that maximum resistances depend on anchor embedment ratio and anchor spacing ratio S/D. Agreement between uplift capacities from laboratory tests and finite element modelling using PLAXIS is excellent for anchors up to embedment ratios of 6.

• Korean Journal of Soil Science and Fertilizer
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• v.32 no.2
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• pp.199-202
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• 1999

The experiment was conducted to find changes of growth response, free proline content and organic acids on manganese chloride toxicity($4,000mg\;l^{-1}$) for germination and early growth in rice. Root growth was increased in kinetin $10^{-3}M$ compared with control and germination rate was also increased in kinetin $10^{-3}M$ as 89%. Chlorophyll contents was slightly increased in kinetin $10^{-3}M$. Free proline content at 3days in Mn $4,000mg\;l^{-1}$ was higher than at 7 and 10 days, and all kinetin concentrations promoted free proline content. In organic acids, particularly, malic acid was remarkably increased in kinetin $10^{-3}M$ compared with control and Mn $4,000mg\;l^{-1}$.

• Health Policy and Management
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• v.1 no.1
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• pp.95-108
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• 1991

The World Health Organization and its member states, in 1978, declared that primary health care is a key to attain the goal of Health for All by the goal of Health for All by the yeas 2000. As a member state of WHO, the Republic of Korea has participated in the declaration of ALMA-ATA and committed to put national efforts for devedoping and implementing primary health care approach with the spirit and content of this Declaration. Since 1978, to translate the spirit of the Declaration into realization, Korean goverment has developed a new category of health manpower such as Community Health Practitioners serving people living in remote rural areas and Village Health Workers serving voluntarily their own village, strengthened the function of Health Centers and Health Subcenters through their reorientation and improved the infrastructure by their new construction or renovation. While primary health care is viewed as an essential health care in Korea, there are some circles who follow a narrow definition in referring to the health care at the periphey of a health system, which is erroneous. Considering the PHC is accepted as the best alternative approach to health care to solve problems that modern health systems are facing, we propose the followings as desirable health policy directions that modern health systems are facing, we propose the followings as desirable health policy directions which might translate the persopective into action at the national level after reviewing past and current PHC approach in Korea : 1. To improve the equity through the reduction of gaps between those who have access to health care and those who have not. 2. To reinforce multisectoral approach and intersectoral coordination through the re- establishment of the National Health Council or establishment of equivalent organization at the central level. 3. To stengthen community participation through lacal people's empowerment by leadership training, changing planning process from the top-down approach to bottom-up and giving the priority to human resources rater than technology, 4. To reinforce the Ministries of Health and Social Affairs through upgrading its role and function to Coordinate Ministries which involve human welfare policies, and creating a Division which is in charge of PHC in the Ministry.

• KIISE Transactions on Computing Practices
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• v.23 no.7
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• pp.428-433
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• 2017

Recently, the demand for high performance non-volatile memory storage devices that can replace existing hard disks has been increasing in environments requiring high performance computing such as data-centers and social network services. The performance of such non-volatile memory can greatly depend on the interface between the host and the storage device. With the evolution of storage interfaces, the non-volatile memory express (NVMe) interface has emerged, which can replace serial attached SCSI and serial ATA (SAS/SATA) interfaces based on existing hard disks. The NVMe interface has a higher level of scalability and provides lower latency than traditional interfaces. In this paper, an evaluation and analysis are conducted of the performance of NVMe storage devices through various workloads. We also compare and evaluate the cost efficiency of NVMe SSD and SATA SSD.

• Asian-Australasian Journal of Animal Sciences
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• v.23 no.8
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• pp.1007-1012
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• 2010

The aim of the present study was to describe whether abnormal cervical mucus discharge (A-CMD) or pathogens in cervical mucus discharge (CMD) have effects on reproductive performance of cows and heifers in estrus. Animals having clear discharges (68 cows, 38 heifers) with normal viscosity and without bad odor were grouped as normal cervical mucous discharge (N-CMD) group. The other animals (84 cows, 32 heifers) were grouped as A-CMD group. Microorganisms isolated from samples were divided into three groups as uterine pathogens (UP), potential uterine pathogens (PUP) or opportunistic uterine pathogens (OUP). Presence of PUP was associated with A-CMD for both cows (p<0.01) and heifers (p<0.02). First service conception rates (FS-CR) were lower in cows positive for PUP (p<0.01). Moreover, presence of PUP and OUP affected FS-CR in heifers (p<0.01). Although A-CMD significantly affected FS-CR in cows (p<0.04), it did not affect FS-CR in heifers. Differences in average open day for cows (p<0.02) and first service age for heifers (p<0.01) were significant between N-CMD and A-CMD groups, respectively. The current study suggested that CMD should be evaluated more carefully when there are infertility problems. In addition to the known microorganism that causes sterility and infertility in the UP group, pathogens in the PUP group should be considered for their potential to cause infertility.

• Earthquakes and Structures
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• v.11 no.3
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• pp.483-503
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• 2016

This study aims to evaluate seismic performance of existing low and mid-rise reinforced concrete buildings by comparing their displacement capacities and displacement demands under selected ground motions experienced in Turkey as well as demand spectrum provided in 2007 Turkish Earthquake Code for design earthquake with 10% probability of exceedance in 50 years for soil class Z3. It should be noted that typical residential buildings are designed according to demand spectrum of 10% probability of exceedance in 50 years. Three RC building sets as 2-, 4- and 7-story, are selected to represent reference low-and mid-rise buildings located in the high seismicity region of Turkey. The selected buildings are typical beam-column RC frame buildings with no shear walls. The outcomes of detailed field and archive investigation including approximately 500 real residential RC buildings established building models to reflect existing building stock. Total of 72 3-D building models are constructed from the reference buildings to include the effects of some properties such as structural irregularities, concrete strength, seismic codes, structural deficiencies, transverse reinforcement detailing, and number of story on seismic performance of low and mid-rise RC buildings. Capacity curves of building sets are obtained by nonlinear static analyses conducted in two principal directions, resulting in 144 models. The inelastic dynamic characteristics are represented by "equivalent" Single-Degree-of- Freedom (ESDOF) systems using obtained capacity curves of buildings. Nonlinear time history analysis is used to estimate displacement demands of representative building models idealized with (ESDOF) systems subjected to the selected ground motion records from past earthquakes in Turkey. The results show that the significant number of pre-modern code 4- and 7-story buildings exceeds LS performance level while the modern code 4- and 7-story buildings have better performances. The findings obviously indicate the existence of destructive earthquakes especially for 4- and 7-story buildings. Significant improvements in the performance of the buildings per modern code are also obvious in the study. Almost one third of pre-modern code buildings is exceeding LS level during records in the past earthquakes. This observation also supports the building damages experienced in the past earthquake events in Turkey.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1333-1337
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• 2014

Background: Astrocytic tumors, the most common primary glial tumors of the central nervous system, are classified from low to high grade according to the degree of anaplasia and presence of necrosis. Despite advances in therapeutic management of high grade astrocytic tumors, prognosis remains poor. In the present study, the frequency and prognostic significance of c-erb-B2 in astrocytic tumors was investigated. Materials and Methods: Records of 72 patients with low- and high-grade astrocytic tumors were evaluated. The expression of C-erbB-2 was determined immunohistochemically and intensity was recorded as 0 to 3+. Tumors with weak staining (1+) or no staining (0) were considered Her-2 negative, while tumors with moderate (2+) and strong (3+) staining were considered Her-2 positive. Results: Of the 72 patients, 41 (56.9%) had glioblastoma (GBM), 10 (13.9%) had diffuse astrocytoma, 15 (20.8%) had anaplastic astrocytoma, 6 (8.3%) had pilocytic astrocytoma. C-erbB-2 overexpression was detected in the tumor specimens of 17 patients (23.6%). Six (8.3%) tumors, all GBMs, exhibited strong staining, 2 (2.7%) specimens, both GBMs, exhibited moderate staining, and 9 specimens, 5 of them GBMs (12.5%), exhibited weak staining. No staining was observed in diffuse astrocytoma and pilocytic astrocytoma specimens. Median overall survival of patients with C-erbB-2 negative and C-erbB-2 positive tumors were 30 months (95%CI: 22.5-37.4 months) and 16.9 months (95%CI: 4.3-29.5 months), respectively (p=0.244). Conclusions: Although there was no difference in survival, C-erbB-2 overexpression was observed only in the GBM subtype.

• Proceedings of the KWS Conference
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• 2002.10a
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• pp.726-731
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• 2002

Reaction synthesis is a process to form ceramics, intermetallics and their composites from elemental powder mixture. Application of this process to a surface modification techniques has a possibilities to enable the process at a lower temperature or for a shorter time, although synthesized materials are likely to include voids and unreacted elements. This paper intend to examine the effect of Si addition to the mixture of Al and Ni on the densification of synthesized Ni-Al intermetallic compounds and to evaluate the surface properties of obtained coatings. By the Si addition, exothermic reaction temperature to form Ni-Al intermetallic was lowered to be below the melting point of Al. Si soluted $Al_3$Ni$_2$, $Al_3$Ni and $Al_{6}$Ni$_3$Si were mainly formed in the coating layer when powder mixture was heated to 973K for 300s. Besides, densification was enhanced by increasing hot press pressure, Si additions and heating rate. When the composition of eutectic Al-Si reaches 78%, void ratio of sintered compact reduced to 0.4%. It is caused by higher flowability of Al-Si liquid phase generated and its infiltration into the void. Since the hardness of NiAl(Si) compound (about 600HV) formed in the coating layer is higher than that of Ni-Al compound (about 400HV), coating layer with high density and superior wear property is obtained by hot press using reaction synthesis from Al-Ni-Si powder mixture.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.2
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• pp.737-740
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• 2015

Purpose: The study aim was to assess factors that impact on the outcome of radioiodine therapy in patients diagnosed with differentiated thyroid carcinoma (DTC). Materials and Methods: We performed a retrospective cohort study on 256 patients with DTC who underwent thyroidectomy and received radioiodine therapy during December 2003 to January 2012. All patients were followed up for at least 1 year. They were considered diseasefree by the criteria of the revised American Thyroid Association Management Guideline for Patients with Thyroid nodules and DTC (ATA guideline 2009). Results: On Cox univariate analysis, factors associated with disease-free status were age<45, stage I tumor, low risk group by histopathology, unifocal tumor involvement, stimulated serum Tg level at 1st dose of radioiodine therapy and no distant metastasis from 1st post-treatment WBS (post RxWBS). On multivariate analysis, stage I tumor and stimulated serum Tg level at 1st dose of radioiodine therapy < 30 ng/mL were the significant prognostic factors that increased disease-free rate by 1.73 times and 2.60 times, respectively (P-value <0.05). Conclusions: Factors affecting the outcome of radioiodine therapy in our study were age, stage, risk of recurrence by histopathology, unifocal tumor involvement and 1st postRxWBS findings. From these factors, stage I tumor and stimulated serum Tg level at 1st dose of radioiodine therapy were independent prognostic factors that substantial increase the disease-free rate.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2004.11a
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• pp.138-149
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• 2004

In this study, we analyzed the gene expression data of Saccharomyces cerevisiae obtained from Holstege et al. 1998 to understand the relationship between expression level and nucleotide sequence of a gene. First, the correlation between gene expression and percent composition of each type of nucleotide was computed. It was observed that nucleotide 'G' and 'C' show positive correlation (r ${\geq}$ 0.15), 'A' shows negative correlation (r ${\approx}$ -0.21) and 'T' shows no correlation (r ${\approx}$ 0.00) with gene expression. It was also found that 'G+C' rich genes express more in comparison to 'A+T' rich genes. We observed the inverse correlation between composition of a nucleotide at genome level and level of gene expression. Then we computed the correlation between dinucleotides (e.g. AA, AT, GC) composition and gene expression and observed a wide variation in correlation (from r = -0.45 for AT to r = 0.35 for GT). The dinucleotides which contain 'T' have wide range of correlation with gene expression. For example, GT and CT have high positive correlation and AT have high negative correlation. We also computed the correlation between trinucleotides (or codon) composition and gene expression and again observed wide range of correlation (from r = -0.45 for ATA r = 0.45 for GGT). However, the major codons of a large number of amino acids show positive correlation with expression level, but there are a few amino acids whose major codons show negative correlation with expression level. These observations clearly indic ate the relationship between nucleotides composition and expression level. We also demonstrate that codon composition can be used to predict the expression of gene in a given condition. Software has been developed for calculating correlation between expression of gene and codon usage.