• Title/Summary/Keyword: ASCUS

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Comparison of ASCUS and HPV Hybrid Capture II Test Results (미확정 편평 상피세포와 인체 유두종 바이러스와의 비교)

  • Park, Mi-Soon;Chang, Byung-Soo
    • Proceedings of the Korea Contents Association Conference
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    • 2012.05a
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    • pp.175-176
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    • 2012
  • 세포선별검사에서 ASCUS로 진단된 검체 중 F-UP이 진행되지 않은 검체 179건을 대상으로 HPV High risk factor, Low risk factor를 확인하기 위해서 Hybrid Capture II Test를 하였다. 결과 High risk factor 양성 및 Low risk factor 양성은 전체 179 cases 중 25 cases로 나타났으며, 전체 검체 중 약 15%에 해당되었다. 또한 전체 15%의 양성검체 중 High risk factor 양성은 87%에 해당되는 것을 확인하였다. 결론적으로 효과적인 검진 체계를 갖춘 나라에서도 자궁경부암의 예방이 완전히 해결되지 않고 있는 문제점이 있는 여건을 고려해 볼 때 추적 관찰이 용이하지 않은 경우를 대비해 자궁경부암으로 진행될 수 있는 precancerous lesion의 원인 인자인 HPV 존재 유무를 세포선별검사와 HPV Hybrid Capture II Test를 동시에 시행하는 것이 효과적이라고 사료된다.

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Relationship Between Virulence and Vegetative Compatibility Group of Glomerella cingulata Isolates (Glomerella cingulata의 병원성과 체세포화합성군(Vegetative Compatibility Group) 과의 관계)

  • 남명현;유성준;김홍기
    • Korean Journal Plant Pathology
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    • v.12 no.4
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    • pp.395-401
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    • 1996
  • 국내의 고추, 사과, 포도, 스타티스(statice)에서 분리한 Glomerella cingulata 균주들의 병원성과 체세포화 합성군(vegetative compatibility group : VCG)과의 관계를 조사하였다. 사과, 포도, 스타티스에서 분리된 균주들은 전기주에 모드 병원성을 나타내었으나 고추에는 병원성이 없었다. 한편, 고추에서 분리된 균주들은 무상처접종시 병원성을 나타내지 못하였다. Nitrate nonutilizing(nit) mutant는 1.5%의 KClO\ulcorner을 첨가한 최소배지에서 선발하였다. nit mutnat들은 nit1, nit2, nit3, nitM의 4가지 표현형 중 하나에 속하였다. VCG는 표현형이 다른 nit mutan간의 대치배양을 통해 결정하였는데 사과, 포도, 스타티스에서 분리한 균주들간에는 같은 VCG를 나타낸 반면 고추에서 분리된 균주들은 다른 VCG로 나타났다. 따라서 G. cingulata 균주들의 체세포화합성은 병원성과 밀접하게 관련되어 있음을 알수 있었다. 또한 동일한 VCG에 속하며 기주가 다른 균주들의 대치배양시 heterokaryon을 형성했으나 자낭을 형성하지는 않았다.

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Note on the New Record of Mitrula paludosa (Geoglossaceae) in Korea (콩나물버섯과 미기록종 Mitrula paludosa (습지등불버섯 : 신칭)의 보고)

  • Park, Yong-Woo;Koo, Chang-Duck;Hong, Dae-Eui;Kim, Tae-Heon
    • The Korean Journal of Mycology
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    • v.37 no.1
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    • pp.104-107
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    • 2009
  • Mitrula paludosa (Geoglossaccae, Helotiales, Ascomycetes) is reported about morphological and ecological characteristics for the first time in Korea. The mushroom fruited on rotten pine leaves or fine twigs in ditches with flowing or standing water in Sogri Mountain National Park from May to June. The apothecium of M. paludosa is 20 to 50 mm tall. The cap is bright yellow to orange, cylindrical to wrinkled ovoid and $5{\sim}10\;{\times}\;10{\sim}20$ mm. The stem is whitish and cylindrical distinctly set off from the cap. The ascospore is hyaline, smooth long elliptical fusoid with round ends and $13{\sim}17\;{\times}\;1.5{\sim}2.0{\mu}m$. The ascus is unitunicate, $90{\sim}110\;{\times}\;5{\sim}6{\mu}m$, and has eight spores biseriately lined to the inoperculate apex. Paraphyses are septate filiform, $95{\sim}120\;{\times}\;1.0{\sim}1.5{\mu}m$, $7{\sim}10{\mu}m$ longer than the asci.

Prevalence and Determinants of High-risk Human Papillomavirus Infection in Women with High Socioeconomic Status in Seoul, Republic of Korea

  • Kim, Ki-Dong;Kim, Jin-Ju;Kim, Sun-Mie;No, Jae-Hong;Kim, Yong-Beom
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.269-273
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    • 2012
  • We aimed to estimate the prevalence of high-risk human papillomavirus (HPV) infections in women of high socioeconomic status (SES) in Seoul, Republic of Korea and to identify risk factors. This study included 13,386 women visiting a prestigious healthcare center located in Seoul between 2003 and 2008. High-risk HPV infections were detected in 994 (7%) and the age-standardized prevalence was 8%. Abnormal Pap smear results ${\geq}$ atypical squamous cells of unknown significance (ASCUS) were observed in 280 of 12,080 women (2%). Based on univariate analysis, age, level of education and number of children were associated with high-risk HPV infections. Based on multivariate analysis, age and high-risk HPV infections had an inverse relationship. In women with high SES in Seoul, the prevalence of high-risk HPV infection was 7% and the age-standardized prevalence was 8%. Age was a strong determinant of high-risk HPV infection.

Identification of Fusarium leaf spot(Fusarium nivale) newly reported In Korea (수도갈색엽고병(Fusarium nivale)의 동정)

  • Kwon Shin Han;Song Hi Sup;Sohn Cheong Yeol;Yamakuchi Tomio
    • Korean journal of applied entomology
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    • v.12 no.3
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    • pp.121-124
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    • 1973
  • From the new rice variety Tong-il, disease symptoms similar to Fusarium leaf spot reported in Japan was observed in Korea. Causal organism was isolated and identified as Fusarium nivale causing Fusarium leaf spot through the study of conidia shape, ascus formation on diseased spot, and ascospore. These results also showed good agreement with that of other investigators. Under the field condition, marked occurrence of this disease has observed by heavy nitrogen application. The optimum temperature for the growth of this fungus was $24^{\circ}C$.

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Deep Learning Algorithm to Identify Cancer Pictures (딥러닝 기반 암세포 사진 분류 알고리즘)

  • Seo, Young-Min;Han, Jong-Ki
    • Journal of Broadcast Engineering
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    • v.23 no.5
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    • pp.669-681
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    • 2018
  • CNN (Convolution Neural Network) is one of the most important techniques to identify the kind of objects in the captured pictures. Whereas the conventional models have been used for low resolution images, the technique to recognize the high resolution images becomes crucial in the field of artificial intelligence. In this paper, we proposed an efficient CNN model based on dilated convolution and thresholding techniques to increase the recognition ratio and to decrease the computational complexity. The simulation results show that the proposed algorithm outperforms the conventional method and the thresholding technique enhances the performance of the proposed model.

Root Rot of Bottle Gourd Stock of Watermelon Caused by Monosporascus cannonballus in Korea (수박 대목용 참박에 발생한 Monosporascus cannonballus에 의한 검은점뿌리썩음병(黑点根腐病))

  • 박경석;남상현;김충회
    • Korean Journal Plant Pathology
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    • v.10 no.3
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    • pp.175-180
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    • 1994
  • The fungal pathogen Monosporascus annonballus was first isolated in Korea from the rotted roots of bottle gourd stocks of collapsed watermelon plants in fields near Chochiwon, Choongnam province in July, 1993. Perithecia of M. cannonballus were dark brown to black, globose, 220~570 ${\mu}{\textrm}{m}$ in diam. and had many asci. Asci are hyaline, clavate to pyriform, and 50~120$\times$35~570 ${\mu}{\textrm}{m}$ in size. Ascospores were aseptate, dark brown to black, globose, 25~45$\times$30~50 ${\mu}{\textrm}{m}$ in diam, and borne singly in each ascus. The fungus grew in the temperature range of 4 to 34$^{\circ}C$, best at 3$0^{\circ}C$. The optimum pH for growth was 6.8. Mycelial growth rate of M. cannonballus was 25.5mm/day on PDA at 26$^{\circ}C$. Perithecia began to form after 20-day-growth on PDA and produced mature asci after 30 days or later. In the greenhouse inoculation tests, the fungus developed water-soaked lesions on roots of bottle gourd seedlings and was then reisolated from the lesions. Severed damages on watermelon plants by M. cannonballus are greatly concerned in Korea, since no stocks used for watermelon cultivation have reported to be resistant to the fungus.

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Comparison of p16INK4a Immunocytochemistry with the HPV Polymerase Chain Reaction in Predicting High Grade Cervical Squamous Intraepithelial Lesions

  • Indarti, Junita;Fernando, Darrell
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.4989-4992
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    • 2013
  • Aim: To compare p16INK4a immunocytochemistry with the HPV polymerase chain reaction in predicting high grade cervical squamous intraepithelial lesions. Materials and Methods: This diagnostic case-control study was conducted from January 2010 until December 2010. We obtained 30 samples, classified according to the degree of cervical intraepithelial neoplasia (CIN): 11 samples for CIN 1, 9 samples for CIN 2, and 10 samples for CIN 3. HPV PCR, p16INK4a immunocytochemistry, and histopathological examination were performed on all samples. Statistical analysis was conducted using SPSS 20.0. Results: In predicting CIN 2-3, we found p16INK4a to have similar specificity and positive predictive value as HPV PCR (95%, 97.2% vs 96.7%), but better sensitivity (87.5% vs 72.5%) and negative predictive value (82.1% vs 67.6%). The most prevalent types of high-risk HPV in our study were HPV 33, 35, 58, 52, and 16. Conclusions: p16INK4a has better diagnostic values than HPV PCR and may be incorporated in the triage of ASCUS and LSIL to replace HPV PCR. Genotype distribution of HPV differs in each region, providing a challenge to develop HPV vaccines based on the epidemiology of HPV in that particular region.

Observation of Anamorph (Libertella sp.) and Teleomorph (Diatrype stigma) of D. stigma Affecting Bed-log of Oak-mushroom in Korea (우리나라의 표고골목을 가해하는 주홍꼬리버섯의 불완전세대와 완전세대 관찰)

  • Bak, Won-Chull;Lee, Bong-Hun;Yoon, Kab-Hee;Ka, Kang-Hyeon;Choi, Joong-Sigk;Lee, Tai-Soo
    • The Korean Journal of Mycology
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    • v.28 no.1
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    • pp.38-40
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    • 2000
  • Anamorph and teleomorph of Diatrype stigma on the bed-log inoculated with oak-mushroom (Lentinula edodes) in Korea were observed and identified. As the characters of anamorph of Diatrype stigma, conidia were hyaline, falcate or slightly curve, and $1{\sim}1.5{\times}12.5{\sim}17.5\;{\mu}m$, and conidia layer was confirmed under the bark. About teleomorph, perithecia $150{\sim}200{\times}450{\sim}500\;{\mu}m$, with ostiole ($30{\sim}40\;{\mu}m$, three- to four-sulcate). Size of ascus containing 8 ascospores was $5{\sim}6{\times}30{\sim}40\;{\mu}m$. Ascospores were hyaline to pale brown, $1.5{\sim}2{\times}5{\sim}7.5\;{\mu}m$ and mostly biguttulate.

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Prevalence of Abnormal Papanicolaou Test Results and Related Factors among Women Living in Zanjan, Iran

  • Maleki, Azam;Ahmadnia, Elahe;Avazeh, Azar;Mazloomzadeh, Saeideh;Molaei, Behnaz;Jalilvand, Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.6935-6939
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    • 2015
  • Background: Currently, a comprehensive program for screening and early detection of cervical cancer does not exist in Iran. This study aimed to determine the prevalence of abnormal Papanicolaou (Pap) smears and some related factors among women living in Zanjan, Iran. Materials and Methods: This cross-sectional study was conducted in 2012 in Zanjan on 4274 married women aged 20-65 years. The study participants were selected through two-stage cluster sampling. After obtaining written consent, demographic and fertility questionnaires were completed. Samples from cervix were obtained through a standard method using the Rover Cervex- Brush. Evaluation and interpretation of the samples were reported using the Bethesda 2001 method. Data were statistically analyzed using chi-square and logistic regression models. Results: Most inflammatory changes in the samples were mild (37.4%). Abnormal atypical changes in the epithelial cells were found in 4.04%. The highest percentage of abnormal changes in the epithelial cells was atypical squamous cells of undetermined significance (ASCUS) (1.9%). Abnormal results of Pap smear was significantly and independently associated with age, papillomavirus infection, and lack of awareness about Pap smear tests. Conclusions: Given the high prevalence of inflammatory and precancerous changes in this study, compared to other studies in Iran and other Muslim countries, and the effect of demographic variables and individual factors on abnormal results, increasing the awareness of women and their families regarding the risk factors for cervical cancer, preventive measures such as screening, and timely treatment seem necessary.