• Korean Journal of Environmental Biology
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• v.34 no.2
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• pp.107-115
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• 2016

Currently, there are 442 operating nuclear power plants in the world, and 62 more are under construction. According to this reasoning, the treatment of radioactive waste is important to prevent the environmental ecosystem including humans, animals, and plants. Especially, a leakage of radioactive waste causes not only regional problem but also serious global one. In this study, we demonstrate the effect of radioisotopes (e.g., cesium, strontium, and cobalt) on a 3D culture cell. To develop the 3D cell culture system, we used a 96-well-culture plate with biocompatible agarose hydrogel. Using this method, we can perform the 3D cell culture system with three different cell lines such as HeLa, HepG2, and COS-7. In addition, we conducted a cell viability test in the presence of radioisotopes. Interestingly, the 3D morphological cells showed 42% higher cell viability than those on the 2D against cesium. This result indicates that the 3D platform provides cells morphological and physiological characteristic similar to in vivo grown tissues. Moreover, it overcomes the limitation of conventional cell culture system that can't reflect in vivo systems. Finally, we believe that the proposed approach can be applied a new strategy for simple high-throughput screening and accurate evaluation of metal toxicity assay.

• Annals of Laboratory Medicine
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• v.38 no.6
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• pp.610-612
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• 2018

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2019.05a
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• pp.365-366
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• 2019

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.1229-1234
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• 2004

Face robots capable of expressing their emotional status, can be adopted as an e cient tool for friendly communication between the human and the machine. In this paper, we present a face robot actuated with arti cial muscle based on dielectric elastomer. By exploiting the properties of polymers, it is possible to actuate the covering skin, and provide human-like expressivity without employing complicated mechanisms. The robot is driven by seven types of actuator modules such as eye, eyebrow, eyelid, brow, cheek, jaw and neck module corresponding to movements of facial muscles. Although they are only part of the whole set of facial motions, our approach is su cient to generate six fundamental facial expressions such as surprise, fear, angry, disgust, sadness, and happiness. Each module communicates with the others via CAN communication protocol and according to the desired emotional expressions, the facial motions are generated by combining the motions of each actuator module. A prototype of the robot has been developed and several experiments have been conducted to validate its feasibility.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2003.09b
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• pp.71-75
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• 2003

오류 역전파 학습 알고리즘을 이용하여 영상 인식에 적용 할 경우에는 은닉층의 노드 수를 경험적으로 설정하므로, 학습시간과 지역최소화 및 정체현상이 발생한다. 그리고 ARTI 알고리즘은 입력 패턴과 저장 패턴간의 측정 방법인 유사성 검증 방법과 경계 변수의 설정에 따라 인식률이 좌우된다. 경계 변수의 값이 크면 입력 패턴과 저장 패턴사이에 약간의 차이만 있어도 새로운 카테고리(Category)로 분류하고, 반대로 경계 변수의 값이 적으면 입력 패턴과 저장 패턴 사이에 많은 차이가 있더라도 유사성이 인정되어 입력 패턴들을 대략적으로 분류한다. 따라서 ART1 알고리즘을 영상 인식에 적용하기 위해서는 경계 변수를 경험적으로 설정하므로 인식률에 부정적인 영향을 갖는 문제점이 있다. 따라서 본 논문에서는 개선된 ART1 알고리즘과 지도 학습 방법을 결합하여 신경망의 은닉층 노드를 동적으로 변화시키는 자가 생성지도 학습 알고리즘을 제안한다. 제안된 신경망에서 입력층과 은닉층의 학습 구조에는 ART1 알고리즘을 개선하여 적용하고, 은닉층과 출력층의 학습 구조에는 은닉층에서 승자로 선택된 노드와 출력층 노드와 연결된 가중치만을 조정하고 Delta-Bar-Delta 알고리즘을 적용한다. 제안된 방법의 학습 성능을 분석하기 위하여 학생증 영상에서 추출한 학번 패턴 분류에 적용한 결과, 기존의 신경망 학습 알고리즘보다 학습 성능이 개선됨을 확인하였다.

• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2367-2370
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• 2014

"Cat's eye"-shaped $[^{57}Co]CoO@SiO_2$ core-shell nanostructure was prepared by the reverse microemulsion method combined with radioisotope technique to investigate a potential imaging agent for a single photon emission computed tomography (SPECT) in nuclear medicine. The core cobalt oxide nanorods were obtained by thermal decomposition of $Co-(oleate)_2$ precursor from radio isotope Co-57 containing cobalt chloride and sodium oleate. The $SiO_2$ coating on the surface of the core cobalt oxide nanorods was produced by hydrolysis and a condensation reaction of tetraethylorthosilicate (TEOS) in the water phase of the reverse microemulsion system. In vivo test, micro SPECT image was acquired with nude mice after 30 min of intravenous injection of $[^{57}Co]CoO@SiO_2$ core-shell nanostructure.

• Journal of Radiation Industry
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• v.10 no.4
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• pp.199-204
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• 2016

The dependence of cell survival on exposure dose and the duration of the liquid-holding recovery (LHR) was obtained for diploid yeast cells irradiated with ionizing radiation of different linear energy transfer (LET) and recovering from radiation damage without and with various concentrations of cisplatin - the most widely used anticancer drug. The ability of yeast cells to recover from radiation damage was less effective after cell exposure to high-LET radiation, when cells were irradiated without drug. The increase in cisplatin concentration resulted in the disappearance of this difference whereas the fraction of irreversible damage was permanently enlarged independently of radiation quality. The probability of cell recovery was shown to be constant for various conditions of irradiation and recovery. A new mechanism of cisplatin action was suggested according with which the inhibition of cell recovery after exposure to ionizing radiations was completely explained by the production of irreversible damage.

• Proceedings of the Korea Multimedia Society Conference
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• 2000.11a
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• pp.245-249
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• 2000

종래의 출입국 관리자는 여권을 재시하면 여권을 육안으로 검색하고 수작업으로 정보를 입력하여 여권 데이터베이스와 대비하는 것이었다. 본 논문에서는 이러한 단점을 보완하고 자동적으로 인증하기 위한 영상 처리와 문자 인식을 통한 여권 인증 시스템에 관한 연구이다. 여권에는 사용자에 대한 많은 정보들이 있다. 이러한 사항을 이용하여 여권에서 추출할 수 있는 문자 정보들에 대해 개선된 ARTI알고리즘을 적용하여 학습하고 자동적으로 인식하도록 하였다.

• 한국약용작물학회:학술대회논문집
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• 2008.05a
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• pp.97-98
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• 2008

• 한국약용작물학회:학술대회논문집
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• 2008.05a
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• pp.95-96
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• 2008