• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.2072-2072
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• 2009

최근 연구들에서, 증강 현실(Augmented Reality; AR) 환경에서의 촉각 상호작용에 대한 가능성이 논의되었다. 비젼 기반의 트래킹을 기초로 한 증강 현실 기술은 미리 정의된 2차원 마커(marker)를 이용하여, 카메라로부터 획득된 실시간 영상 위에 가상 물체를 증강한다. 그러나, 카메라로부터 획득된 데이터는 몇몇 오차 요인들, 예를 들어 마커의 위치를 인식하는데 나타나는 오차, 카메라 안에 존재하는 센서 잡음 등으로 인해서 마커 잡음(마커를 인식하면서 나타나는 잡음)이 불가결하게 발생하게 된다. 이러한 이유로 인해서, 사용자가 한 손에는 마커를, 다른 한 손으로는 촉감 장치를 이용하여, 마커에 증강된 물체를 만질 때, 마커 잡음은 힘의 떨림(force trembling)을 발생시킨다. 심지어, 이러한 현상은 정지된 마커에 증강된, 마커가 움직이지 않는 상황에서도 발생한다. 게다가, 마커 위에 증강된 물체가 약간 빠른 속도로 이동하게 될 경우, 측정된 이동 거리는 연속적인 프레임(frame)들 간의 불연속적일 수 있다. 만약 사용자가, 대략 30Hz로 위치와 방향이 갱신되는 가상물체를 촉각적으로 상호작용하려 한다면, 계산되는 반력은 급작스런 힘의 변화를 생성하게 될 수도 있다. 이러한 현상을 극복하기 위해서, 마커 잡음을 최소화하기 위해서 정적 임계값(constant threshold)을 이용할 뿐만 아니라, 보간법을 같이 사용한 방법이 있었다. 하지만, 이러한 방법은 정적 임계값을 이용하고, 영상 프레임 갱신 속도와(video frame rate)와 촉각 프레임 갱신 속도가 일정하다는 가정을 사용하였기 때문에, 여전히 힘의 불연속적인 발생이 나타난다. 따라서, 이 논문에서는 두 가지 방법을 이용하여 증강 현실 내에서, 발생할 수 있는 힘의 불연속적인 변화를 보정하는 두 가지 방법, 잡음 제거를 위한 확장된 칼만 필터(Extend Kalman Filter)와 영상과 촉각 갱신 속도 차이에 따른 갑작스런 힘의 변화를 제거하기 위한 적응적 외삽법(Adaptive Extrapolation method)을 제안한다.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.4
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• pp.502-506
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• 2010

An augmented book is an application that augments such multimedia elements as virtual 3D objects generated by computer graphics, movie clips, or sound clips to a real book using AR technologies. It is intended to bring additional education and entertainment effects to users. For augmented books, this paper proposes an adaptive keyframe-based page tracking method to estimate the camera's 6 DOF pose in real-time after recognizing a page and performing wide-baseline keypoint matching. For a page tracking, proposed method in this paper chooses a proper keyframe and performs a tracking in two step of coarse-to-fine stage. As a result, the proposed method in this paper guarantees a robust tracking to view-point and illumination variations and real-time.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.4
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• pp.135-140
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• 2013

With the advent of smart phones recently, users have experienced a new way of communicating using a smart phone without the constraints of time and space. As a result, users are ubiquitous around the user's own resources and a variety of natural interaction that was required. In particular, the interaction between the user and the content in the virtual reality and augmented reality, otherwise your content or service in the real world and the virtual direct and intuitive interaction can be. In this paper, we use Augmented Reality smart-phone sitting in the subway system that allows people to know the arrival station is designed to offer.

• Journal of Aquaculture
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• v.8 no.3
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• pp.209-220
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• 1995

The nuclear matrix was isolated from Misgumus mizolepis liver nuclei by low salt extraction and restriction enzyme treatment. The structure was digested with proteinase K. After centrifugation, matrix attachment regions (MARs) were obtained by RNase treatment and phenol-chloroform extraction. The result leads to the appearance of smeared bands in the range of about 0.3-15 kb. pURY19 vector was constructed by inserting 2.13 kb Eco47 III fragment of the yeast uracil 3 gene into the unique Ssp I site of pUC19 plasmid vector as a selection marker. This vector is unable to be maintained in Sacrharomyces cerevisiae by itself since it cannot replicate as an extrachromosomal element. Using this system, we attempted cloning the ARS (autonomously replicating sequence) from M. mizelepis to develop an efficient expression vector for the transgenic fish. pURY19N_{l-62}$ were constructed by inserting MARs in pURY19 plasmid vector and transformation of E. coli $DH5\alpha$. Replication origins (ARS) of M. mizolepis were isolated, which enabled the vector to replicate autonomously in S. cerevisiae. The cloned DNA fragments were sequenced by Sanger's dideoxy-chain termination method. All clones were AT-rich. $pURY19N_6$, one of the clones, expecially contained ARS consensus sequence, Topoisomerase II consensus, near A-box and T-box.

• Tuberculosis and Respiratory Diseases
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• v.68 no.4
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• pp.212-217
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• 2010

Background: Acyl protein thioesterase-1 (APT1) is a cytosolic protein that may function in the depalmitoylation of numerous proteins, including the Ras family. However, the clinical role of depalmitoyl thioesterase in human cancer is not known. We evaluated the APT1 expression in lung cancer tissue and its clinicopathological findings according APT1 expression pattern. Methods: APT1 expression was examined by immunohistochemistry in the tumor tissue from 79 patients, who had undergone curative surgical removal of the primary lesion; all patients had been diagnosed with stage I non-small cell lung cancer between 1993 and 2004, at Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. Results: The APT1 expression was seen in 50 out of 79 (63.3%) cases. The positive APT1 expression was significantly related with histologic subtype and T stage, but was not influenced by differentiation. The positive APT1 expression was not significantly related to patient age, gender, or smoking history. The median follow-up duration was 10.0 years; the 5-year survival rate was 71.0%. The positive APT1 expression group showed significantly worse overall survival and worse disease-free survival without statistical significance. Conclusion: We conclude that positive APT1 expression in stage I lung cancer after surgery is closely associated with overall survival. To evaluate APT1 as a prognostic marker in lung cancer, comprehensive studies on advanced stage cases are needed.

• Tuberculosis and Respiratory Diseases
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• v.65 no.6
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• pp.495-503
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• 2008

Background: Epigenetic alterations in certain genes are now known as at least important as genetic mutation in pathogenesis of cancer. Especially abnormal hypermethylation in or near promoter region of tumor suppressor genes (TSGs) are known to result in gene silencing and loss of gene function eventually. The authors tried to search for new lung cancer-specific TSGs which have CpG islands and HpaII sites, and are thought to be involved in carcinogenesis by epigenetic mechanism. Methods: Tumor tissue and corresponding adjacent normal tissue were obtained from 10 patients who diagnosed with non small cell lung cancer (NSCLC) and underwent surgery in Konyang university hospital in 2005. Methylation profiles of promoter region of 21 genes in tumor tissue & non-tumor tissue were examined with HpaII-MspI methylation microarray (Methyl-Scan DNA chip$^{(R)}$, Genomic tree, Inc, South Korea). The rates of hypermethylation were compared in tumor and non-tumor group, and as a normal control, we obtained lung tissue from two young patients with pneumothorax during bullectomies, methylation profiles were examined in the same way. Results: Among the 21 genes, 10 genes were commonly methylated in tumor, non-tumor, and control group. The 6 genes of APC, AR, RAR-b, HTR1B, EPHA3, and CFTR, among the rest of 11 genes were not methylated in control, and more frequently hypermethylated in tumor tissue than non-tumor tissue. Conclusion: In the present study, HTR1B, EPHA3, and CFTR are suggested as possible novel TSGs of NSCLC by epigenetic mechanism.

• Journal of the Korean association of regional geographers
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• v.6 no.3
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• pp.153-168
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• 2000

An estuarine marsh is semi -inclosed inlets, located between coastal and terrestrial environment. The sediment transport by river and tide through tidal river and vertical accretion by sediment accumulation are important processes in estuarine marsh. An analysis of the vertical accretion rate at various time scale is important work for understanding and managing coastal environments. The purpose of this study is to determin the spatial characteristics of vertical accretion rate in an estuarine marsh, Sunchon Bay, in the southern coastal region of Korean peninsula. The methods of analysis are sedimentation rate by individual tidal cycle, annual accretion rate, concentration of total suspended load in water column. Spatial characteristics of sedimentation rate by individual tidal cycle was investigated using 30 filter paper traps. Sedimentation rate by individual tidal cycle at levee edge was higher than that at back marsh. The sedimentation rate decreased with distance from estuarine front. Levee effect and proximity to the turbidity maximum zone result in a higher sedimentation rate in the levee edge. There is a weak relation-ships between tidal regime and sedimentation rate by individual tidal cycle. Spatial cahracteristics of annual accretion rate was investigared using 30 artificial marker plots. Annual accretion rate at back marsh($1.5{\sim}3.5cm/yr$) was higher than that at tidal river levee edge($0.8{\sim}3.0cm/yr$). Total suspended load (TSL) concentrations in water column also indicate this spatial characteristics of annual accretion rate. TSL concentration in water column leaving the vegetation part dramatically decreased. There is a very strong relationship between the concentration of suspended load and accretion rate. These results indicate that annual accretion rate is controlled by vegetation cover and proximity to the turbidity maximum zone. This difference of spatial characteristics of vertical accretion rate ar various time-scale was due to the fact that surface sediment of levee edge was eroded by tide and other factors. The major findings are as follows. First, the spatial characteristics of vertical accretion rate are different from various time-scale. Second, the major mechanism for the vertical accretion rate in this region is suspended load trapping by vegetation. Third, this region is primarily a depositional regime over the time-scale of the present data Fourth, this estuarine marsh is accreting at rates beyond other area.