• BMB Reports
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• 제39권1호
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• pp.16-21
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• 2006

The coat protein (CP) of Papaya ringspot virus (PRSV) was analyzed for presentation of the antigenic peptide of animal virus, Canine parvovirus (CPV), in Escherichia coli (E. coli). The 45 nucleotides fragment coding for the 15-aa peptide epitope of the CPV-VP2 protein was either inserted into the PRSV-cp gene at the 5', 3' ends, both 5' and 3' ends or substituted into the 3' end of the PRSV cp gene. Each of the chimeric PRSV cp genes was cloned into the pRSET B vector under the control of the T7 promoter and transformed into E. coli. The recombinant coat proteins expressed from different chimeric PRSV-cp genes were purified and intraperitoneally injected into mice. All of the recombinant coat proteins showed strong immunogenicity and stimulate mice immune response. The recombinant coat proteins containing the CPV epitope insertion at the C terminus and at both N and C termini elicited ten times higher specific antisera in immunized mice compared with the other two recombinant coat proteins which contain the CPV epitope insertion at the N terminus and substitution at the C terminus.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2008년도 한국우주과학회보 제17권2호
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• pp.23.4-23.4
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• 2008

In March and April 2001, the apogee (~9 Re) of the Polar spacecraft was located near the subsolar magnetopause with its orbital plane nearly parallel to a magnetic meridian plane. Polar electric and magnetic field data acquired during the two-month interval of solar maximum have been used to study fundamental standing Alfven waves near the subsolar meridian plane (magnetic local time = 1000-1400 hours) at magnetic latitudes from the equator to $\pm45$ degrees and at L values between 7 and 12. In the frequency band from 1.5 to 10 mHz, fundamental mode oscillations were identified based on high coherence (more than 0.7) and an approximately 90-degree phase shift between the azimuthal magnetic and radial electric field components. The L dependence of the fundamental frequencies is studied, and the frequencies are compared with those observed near the solar minimum interval (Takahashi et al. 2001). We found that the average frequencies in solar maximum are lower than those in solar minimum by a factor of ~2. This implies that the mass density in solar maximum is higher than that in solar minimum by a factor of ~4. Since there is a positive correlation between solar irradiance and solar activity, we suggest that the ionosphere in solar maximum produces more ions and load magnetic flux tubes with more ions.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.145-146
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• 2001

There are increasing evidences that L-ascorbic acid (LAA) is selectively toxic to some types of tumors at physiological concentrations as a prooxidant, rather than antioxidant. However, the mechanism by which LAA initiates cellular signaling toward cell death is still unclear. Therefore, to determine whether LAA might be useful for the treatment of human acute promyelocytic leukemia (APL), HL-60 cells, the effects of LAA on proliferation, redox system, MAPK and induction of apoptotic cascades were investigated.(omitted)

• Journal of Microbiology and Biotechnology
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• 제12권4호
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• pp.702-705
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• 2002

Apicularen A (Api A) was recently isolated from Chondromyces sp. as a potent antitumor agent. Because of its unique chemical structure, a macrolide with a highly unsaturated amide side chain, and potent growth inhibitory effect in various cancer cell lines, Api A is currently in clinical trial for cancer therapy. In the present study, the effect of Api A on in vitro angiogenesis of bovine aortic endothelial cells (BAECS) was investigated. Api A potently inhibited the proliferation of BAECS in a dose-dependent manner. Treatment of the endothelial cells with up to 10 ng/ml of the compound did not show any cytotoxicity. In addition, it inhibited basic fibroblast growth factor (bFGF)-induced invasion and capillary tube formation of BAECS at concentrations of 2-5 ng/ml. These results, therefore, demonstrate that Apl A is a novel antiangiogenic agent and may suppress the growth of tumors, at least in part, by the inhibition of neovascularization.

• 정보처리학회논문지D
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• 제9D권4호
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• pp.687-696
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• 2002

본 논문에서는 홈 제어 네트워크의 대표적 표준으로 자리잡고 있는 LonWorks 시스템의 구성관리 소프트웨어의 플랫폼(LonWare)을 리눅스기반에서 구현한 내용을 기술한다. LonWare는 NMML, LonWare APl, LonWare DB의 3개의 모듈로 이루어져 있고, 응용 프로그램 개발자에게 LonWorks 시스템을 쉽게 접근 및 제어할 수 있는 인터페이스를 제공한다. 또한, 가정 내의 디바이스 네트워크 DB를 가정 내 홈 서버에서 관리하므로 보안상의 단점을 보완할 수 있다.

• Journal of Nutrition and Health
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• 제37권3호
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• pp.169-175
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• 2004

This study was performed to investigate the effect of acorn supplementation on the lipid profile and redox antioxidant enzyme activities in obese rat. Obesity in the rats was induced by feeding diet contained 10％ lard and 0.5％ cholesterol for 4 week. After 4 weeks, rats were divided into the following 5 groups; high fat diet (Control), high fat diet plus 10％ Acorn powder (APlO％), high fat diet plus 20％ Acorn powder (AP20％), high fat diet plus 0.2％ Acorn extract (AE0.2％), high fat diet plus 0.5％ Acorn extract (AE0.5％). Total food intake and food efficiency ratio (FER) was not significantly different by acorn powder and extract supplementation. But, body weight was decreased by 20％ acorn powder. Acorn powder and extract supplementation for 4 weeks tend to decrease total cholesterol and triglyceride level on the serum and hepatic tissue. There was no significant difference in hepatic glutathione (GSH) content among all the groups. The hepatic GST activity in acorn supplemented groups was lower than that of control. Glutathione peroxidase and catalase activities were higher in acorn supplemented groups than that of control. Hepatic TBARS levels of experimental groups were also significantly lower than that of control group. Our finding suggest that acorn powders and extract might have potential role for improving lipid profiles and antioxidant enzyme activities in obese rats.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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• pp.38.3-39
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• 2009

Equatorial Plasma Bubble (herafter, EPB) is a common feature in low-latitude F-region during the night time. Since EPB causes significant impacts on the satellite communication and navigation systems, its accurate forecast is highly demanded by the GNSS users. Thus, further understanding of these features and their configuration is a challenging issue in space weather studies. The day-to-day variability of the plasma bubble activity was investigated by analyzing the TIMED/GUVI, ROCSAT-1, DMSP, and CHAMP satellite data. The pre-reversal enhancement (PRE) is known as the most important single parameter for the onset of plasma bubbles but we do not know yet to what extent the day-to-day variability of the bubble activity can be attributed to the PRE. We obtained the magnitude of the PRE from ROCSAT-1 and the occurrence of bubbles in relation to the PRE was investigated by using the coincident observations of EPBs from TIMED/GUVI, DMSP, and CHAMP. By conducting one-to-one comparison of the PRE characteristics with the EPB occurrence we examined the role of the PRE in the onset of EPBs.

• 한국컴퓨터정보학회논문지
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• 제10권6호
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• pp.219-226
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• 2005

본 논문은 4G 이동 네트워크 환경에서 재구성성을 제공하기 위한 방안으로 PARLAY X기만의 개방형 API에 관하여 서술하였다. 4C이동 네트워크 환경에서는 망 수준에서 문맥인식성, 적응성, 개인화 등과 같은 지능성이 요구된다. 그러나 기존의 PARLAY 기반 서비스 네트워크는 문맥인식성, 적응성, 개인화 등의 지능성에 대한 고려가 부족하다. 그러므로 본 논문의 목적은 4G이동 네트워크 환경에서 문맥인식성, 적응성, 개인화 등이 지원 가능한 개방형 APl를 개발하고자 하는 것이다. 본 논문에서 개방형 API는 사용자 주변에 변화하는 문맥 제약조건 및 사용자 각 개인의 선호도 정보을 파악하여, 변화하는 문맥 제약 조건 및 사용자의 선호도에 따라서 각 개인에게 적합한 적응성 있는 망 서비스를 제공하는 것을 의미하며, 개방형 API를 이용하는 예로 위치와 속도 등의 문맥정보와 사용자의 선호도 정보를 파악한 후에, 사용자에게 망에서 문맥정보 및 사용자 선호도에 따라서 각 개인에게 적합한 차별화된 QoS를 지원하는 경우를 보였다.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2004년도 제5회 압연심포지엄 신 시장 개척을 위한 압연기술
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• pp.285-293
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• 2004

Oxidation behavior of 304 and 430 stainless steel were studied using thin film X-ray analysis and glow discharge spectrum analysis (here-after GDS). The oxidation layer of 304 stainless steel was composed of $Cr_2O_3\;and\;FeCrO_4$ and its thickness was about $1.5{\mu}m$ after $1\~5$ minutes of annealing at $1120^{\circ}C$ open air. However, the oxidation layer of 430 stainless steels was mainly composed of $Cr_2O_3$ and its typical thickness was 0.5um after $1\~5$ minutes of annealing at $1000^{\circ}C$ open air. Electro-chemical analysis revealed that the descaling of oxidation layer could be activated by Fe, Cr dissolution from the matrix behind the oxidation layer at the current density of $5\~10ASD$ and by Fe, Cr-oxide dissolution from the oxidation layer at the current density over than 10ASD. Electrolytic stripping of 430 and 304 revealed the intial incubation period of descaling by oxygen evolving at low current density range such as $5\~10ASD$. However the dissolution of oxide layer was occurred when applying the anodic current of $10\~20ASD$ on 430 and 304 stainless steels. It was suggested that the electrolytic pickling of high Cr bearing stainless steel such as 430 and 304 seemed to be the more effective in the high current density range such as $10\~20ASD$ than the low current density range such as $5\~10ASD$.

• 정보처리학회논문지D
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• 제10D권1호
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• pp.143-152
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• 2003

이기종 플랫폼간의 데이터 교환과 통합을 위한 표준 기술로 XML과 웹 서비스 기술이 각광을 받고 있다. 이러한 기술을 지원하는 XML/A는 클라이언트 응용과 데이터 분석 엔진이 인터넷 상에서 데이터를 교환할 수 있도록 하는 SOAP 기반의 XML 통신 API이다. 데이터가 XML 문서 형태로 교환된다는 점에서 XML/A는 플랫폼 독립적이지만, 클라이언트 응용 개발자들은 서버에 데이터를 요청할 때마다 XML 문서를 생성해야 하고, 서버가 보내는 XML 데이터 검색을 위해 별도의 XML 쿼리 언어를 사용해야 하는 단점이 있다. 본 연구에서는 윈도우즈 환경의 클라이언트 응용 개발자들이 XML/A의 OLAP 관련 서비스를 편리하게 사용할 수 있도록 하는 상위 수준의 클라이너트 OLAP API인 XMLMD를 설계하고 구현하였다. XML/A와 XML/A의 관계는 OLEDB for OLAP과 ADOMD의 응용 사례로써 데이터의 다차원적 분석결과를 인터넷을 통해 제공하는 웹 OLAP 큐브 브라우저도 개발하였다. 이 브라우저는 전송된 데이터를 XML, HTML, 엑셀, 그래프 등의 다양한 형태로 제공한다.