• Title/Summary/Keyword: APRI

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Anthelmintic Efficacy of Tetramisole Against Experimental Infection of Swine Lungworm, Metastrongylus Apri (Tetramisole에 의한 돈폐충(豚肺蟲)(Metastrongylus apri) 구충(驅蟲) 효과(效果)에 대(對)하여)

  • Lee, Byung Do;Kim, Chin Bok
    • Korean Journal of Veterinary Research
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    • v.8 no.1
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    • pp.11-17
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    • 1968

  • Oral and subcutaneous administration of Tetramisole (d1-2, 3, 5, 6-tetrahydro-6-phenyl-imidazo- 2, 1-b thiazole hydrochloride) was effective in controlling the adult and immature forms of Metastrongylus apri in pigs when administered at the dose of 10-12.5 mg per kg of body weight.

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Fluorescence Switching of Conjugated Polyelectrolyte based on Polydiphenylacetylene

  • Lee, W.E.;Kim, J.H.;Sakaguchi, T.;Kwak, G.;Lee, C.L.
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.245.1-245.1
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    • 2013

  • Polydiphenylacetylene (PDPA) derivatives are a class of conjugated polymer that contain intramolecular excimer emission originating the intramolecular stack structure. In contrast with conventional conjugated polymer, the fluorescence property of PDPA significantly depends on the intramolecular stack structure. In this regard, herein, we investigated new fluorescence switching mechanism of conjugated polyelectrolyte (CPE) based on PDPA. The developed CPE showed relatively weak fluorescence emission in water, while the polymer exhibited a great fluorescence amplification behavior by electrostatic complex with proteins. In addition, the CPE is highly sensitive to binding with a little protein despite of turn-on type fluorescence response. We found that the fluorescence switching of the CPE closely relate to a perturbation of the intramolecular stack structure. The new fluorescence switching mechanism of the CPE is very useful for protein assays and discrimination and it also would be provide new sensing approaches as basic sensing mechanism.

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