• 대한추나의학회지
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• 제5권1호
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• pp.213-222
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• 2004

Objectives : To investigate contributing degree of other factors except pelvic tilting to F.L.L.D by analizing with Gonstead technique on the correlation between femur head height discrepancy on the standing pelvic AP view and F.L.L.D caused by pelvic tilting. Method : We analysed standing pelvis AP X-ray of 70 patients who had visited at the department acupunture and moxibustion in Conmaul oriental medical hospital, during May, 1st, 2004 - July, 30th, 2004, with low back pain or lower extremity pain. We excluded the person with any past history of polio, genetic defect, malunited fracture, growth plate injury, infection and overgrowth attributable to hemangioma, or arteriovenous fistula. Results & Conclusion : The functional leg length discrepancy caused by pelvic tilting and femur head height difference had no statistical difference(p=0.132) but poorly correlated(Pearson ${\nu}=0.05$). In the 94.28% of subjects, the femur head height difference wasn't in accord with F.L.L.D. caused by pelvic tilting. In 47.14% of subjects were expected to have over $3^{mm}$ of leg length discrepancy after pelvic adjustment. The mean of measurement difference between two methods was $3.76{\pm}3.12^{mm}$ and the range was $0{\sim}11.4^{mm}$. Consequently, we must consider not only functional leg length discrepancy caused by pelvic tilting but also anatomical leg length discrepancy, misalignment of ankle, knee or hip joint etc.

• Journal of Plant Biotechnology
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• 제6권2호
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• pp.77-85
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• 2004

Development of efficient plant regeneration and genetic transformation protocols (using the Particle Inflow micro-projectile Gun and the shoot-tips as target tissue) of Sorghum bicolor (L.) Moench in terms of expression of the reporter gene, $\beta$-glucuronidase(uidA) is reported here. Two Indian cultivars of sorghum were used in the study, viz. M-35-1 and CSV-15. Plant regeneration was achieved from one-week-old seedling shoot-tip explants via multiple-shoot-clumps and also somatic embryos. The multiple-shoot-clumps were produced on MS medium containing BA (0.5, 1.0 or 2.0 mg/$L^{-1}$), with biweekly subculture. Somatic embryos were directly produced on the enlarged dome shaped expansive structures that developed from shoot-tip explants (without any callus formation) when cultured on MS medium supplemented both with BA (0.5, 1.0 or 2.0 mg/$L^{-1}$) and 2,4-D (0.5 mg/$L^{-1}$). Whereas each multiple-shoot-clump was capable of regenerating more than 80 shoots via an intensive differentiation of both axillary and adventitious shoot buds, the somatic embryos were capable of 90% germination, plant conversion and regeneration. The regenerated shoots could be efficiently rooted on MS medium containing 1.0mg/$L^{-1}$ IBA and successfully transplanted to the glasshouse and grown to maturity with a survival rate of 92%. The plant regeneration efficiency of both the genotypes were similar. After the micro-projectile bombardment, expression of uidA gene was determined by scoring blue transformed cell sectors in the bombarded tissue by an in situ enzyme assay. The optimal conditions comprising a helium pressure of 2200 K Pa, the target distance of 11 cm with helium inlet fully opened and the use of osmoticum have been defined to aid our future strategies of genetic engineering in sorghum with genes for tolerance to biotic and abiotic stresses.

• 약학회지
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• 제40권5호
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• pp.591-598
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• 1996

The water extracts of ten crude drugs were tested for the spasmolytic and anti-peptic ulcer activities on rat ileum smooth muscle contraction and aspirin-induced acute hemorrhag ic erosive gastritis respectively. The water extract of Aurantii immaturi pericarpium(AIP)($IC_{50}=1.5{\times}1O^{-2}$g/l), Aurantii nobilis pericarpium(ANP)($IC_{50}=2.5{\times}1O^{-2}$g/l), Cyperi rhizoma(CR)($IC_{50}=3.3{\times}1O^{-2}$g/l). Linderae radix(LR) ($IC_{50}=6.8{\times}1O^{-2}$), Aurantii fructus immaturus(AFI)($IC_{50}=11.8{\times}1O^{-2}$), Saussureae radix(SR)($IC_{50}=13.2{\times}1O^{-2}$g/l) and Ponciri fructus(PF)($IC_{50}=23.3{\times}1O^{-2}$g/l) showed inhibitory activity on the isometric contraction of rat ileum smooth muscle induced by electrical stimulation in a concentration-dependent manner, whereas the water extracts of Arecae pericarpium(AP), Agastachis herba(AH) and Magnoliae cortex(MC) potentiated the isometric contraction. In the aspirin-induced acute gastritis, the water extracts of MC, AP and CR reduced significantly the gastric juice secretion, gastric juice acidity and pepsin activity. They also showed protective activity of gastric mucosal layer from erosion and petichial hemorrhage in gross and histological examination.

• 대한지리학회:학술대회논문집
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• 대한지리학회 2003년도 추계학회술표회 논문집
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• pp.34-39
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• 2003

밀양강 중류부 충적평야의 화분분석 결과를 통하여 홀로세 후기 동안의 식생환경을 복원하고 한반도 남부지방의 농경의 기원과 확산에 대해 검토하였다. 경상남도 밀양시 산외면 금천리 단장천 충적평야에서 화분분석을 행하였다. 고고학 유적발굴을 위해 절개한 트랜치 T6(14.75-15.90m a.s.l. : 두께 1.15m)과 T9(17.00-15.60m a.s.l. : 두께 1.4m)의 노두 단면 중에서 비교적 유기질이 풍부한 실트층 및 토탄층에서 5cm등간격으로 채취하여 목본화분(AP: Arboreal Pollen)이 200개 이상이 될 때까지 검경하였다. (중략)

• 대한전자공학회논문지
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• 제23권4호
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• pp.571-577
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• 1986

In this paper, we have investigated pole-zero shifting due to variable stopband frequency Ws and passband ripple Ap of elliptic function filters. Also we have studied the phase, group-delay, unit step response and impulse response of elliptic filters. We show that in the passband the phase linearity improves as Ws increases, and eventually it approaches that of a chebyshev function filter.

• Bulletin of the Korean Chemical Society
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• 제33권5호
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• pp.1686-1692
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• 2012

Densities (${\rho}$), Viscosities (${\eta}$) and ultrasonic speeds (u) of pure acetophenone (AP), propiophenone (PP), $p$-methyl acetophenone ($p$-MeAP), $p$-chloroacetophenone ($p$-ClAP) and those of their binary mixtures with $N$-ethyl aniline ($N$-EA) as a common component, were measured at 303.15 K over the entire composition range. These experimental data were used to calculate the excess volume $V^E$, deviation in ultrasonic speeds ${\Delta}u$, isentropic compressibility $K_s$, intermolecular free length $L_f$, acoustic impedance Z, deviations in isentropic compressibility ${\Delta}K_s$, deviation in viscosity ${\Delta}{\eta}$ and excess Gibbs free energy of activation of viscous flow ($G^{*E}$) at all mole fractions of $N$-ethyl aniline. These parameters, especially excess functions, are found to be quite sensitive towards the intermolecular interactions between component molecules. Theoretical values of viscosity of the binary mixtures were calculated using different empirical relations and theories. The relative merits of these relations and theories were discussed. The experimental results were correlated by using the polynomial proposed by Redlich-Kister equation.

• 대한한의학회지
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• 제24권3호
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• pp.84-95
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• 2003

Objective : This study was carried out to investigate the effects of Kamisopunghwalhyeol-tang (Jiaweishujenghuoxie-tang; Kami-SPHHT) on the immunity responses of the Synoviocytes isolated from the patients on rheumatoid arthritis. Methods : Cells were stimulated by $Interleukin-1{\beta}$ and Tumor Necrosis $Factor-{\alpha}$ in the presence or absence of Kami-SPHHT, and then induced cytokine mRNA levels were determined by RT-PCR and real-time quantitative RT-PCR. Results : Levels of $IL-1{\beta},{\;}IL-6,{\;}TNF-{\alpha}$, COX-2, and NOS II mRNA expressions significantly decreased in Kami-SPHHT treated cells compared to non-treated control cells. Also, DNA-binding activity of $NF-{\kappa}B$ and AP-l decreased in Kami- SPHHT treated hFLSs. Conclusion : These results suggest that Kami-SPHHT may be involved in anti-inflammatory reactions by inducing cytokine gene expression in synoviocytes, and further in vivo examination on its efficacy can provide potential application for the treatment of rheumatoid arthritis.

• Archives of Pharmacal Research
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• 제25권4호
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• pp.475-479
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• 2002

Capsaicin, a major pungent constituent of red pepper (Capsicum annuum L.) possesses a vast variety of pharmacologic and physiologic activities. Despite its irritant properties, the compound exerts anti-inflammatory and anti-nociceptive effects. Previous studies from this laboratory revealed that capsaicin, when topically applied onto dorsal skin of female ICR mice, strongly attenuated activation of NF-kB and AP-1 induced by the typical tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), which may account for its anti-tumor promoting activity in mouse skin. In the present work, we have found that capsaicin suppresses TPA-stimulated activation of NF-kB through inhibition of $IkB{\alpha}$ degradation and blockade of subsequent nuclear translocation of p65 in human pro myelocytic leukemia HL-60 cells. Methylation of the phenolic hydroxyl group of capsaicin abolished its inhibitory effect on NF-kB DNA binding. Likewise, TPA-induced activation of AP-1 was mitigated by capsaicin treatment.

• 한국식품저장유통학회지
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• 제24권5호
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• pp.559-564
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• 2017

Probiotics로 알려진 유산균을 다량 포함하고 있으며 우유가 가지고 있는 영양성분을 함유한 액상형 요구르트를 사용하여, 저장성은 높지만 편리성이 낮은 분말형 요구르트의 단점을 개선한, 유동성 및 용해성이 우수한 구형과립 요구르트를 제조하였다. 구형과립 요구르트의 유동층코팅기 최적 제조조건은 반응표면분석방법(RSM design)을 이용하여 설정하였으며, feeding rate(FR) 0.54 mL/min, atomization air pressure(AP) 2.64 bar, product temperature(PT) $58.18^{\circ}C$의 유동층코팅기 운영조건하에서 최대회수율은 79.42%로 예측되었다. 유동층코팅기의 버텀스프레이 방식으로 제조된 구형과립 요구르트는 6-7 log CFU/g의 많은 유산균을 가지고 있었으며, 특히 상대습도 75% 및 저장온도 $25^{\circ}C$ 조건하에서 4개월 동안 유산균수의 감소가 아주 미미하여, 저장성 및 편리성이 증진된 새로운 형태의 유산균 제품 개발에 대한 가능성을 보여주었다.

• 음성과학
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• 제9권2호
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• pp.69-87
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• 2002

This paper investigates how focus contributes to the phonological and phonetic realization of Japanese intonation. Pierrehumbert & Beckman (1988) pointed out that textual prominence results in the H-tone peak raising on the focused item and IP (Intonational Phrase) initiation before the focused item. Similarly Kori (1989) suggested that the F0 peaks on the words after the focused item tend to be suppressed. Although they give a general description of the characteristics of focus phenomena in Japanese intonation, they fail to explain the F0 peak interaction between H phrasal tone and lexically specified pitch accent in more-than-3-mora words whose accent locations varies from early to late. In this paper, we perform the experiment to investigate the following three points. First, we would like to look at the systematic intonational differences between focused and neutral APs; specifically, focused APs, either accented or unaccented, are compared with the neutral counterparts in terms of F0 pattern. Second, we investigate F0 patterns of a focused AP with more than 3 morae, as the accent of the word varies from early to late. Since an AP with a late accent has a H- on the second mora as well as H*+L on its accent mora, it is expected that these peaks will show systematic F0 pattern when it is focused. Our third concern is F0 patterns of a post focus AP with more than 3 morae, that is, whether a post-focus word is dephrased or just downstepped as the word accent location varies from early to late. This paper is significant in that it tries to clarify the F0 peak interaction between H-and lexical pitch accent H*+L in a variety of focus contexts in Japanese intonation.