• Title/Summary/Keyword: AO

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Simulation Skills of RegCM4 for Regional Climate over CORDEX East Asia driven by HadGEM2-AO (CORDEX 동아시아 지역에서 HadGEM2-AO를 경계조건으로 처방한 RegCM4의 상세 지역기후 모의성능)

  • Oh, Seok-Geun;Suh, Myoung-Seok;Cha, Dong-Hyun;Choi, Suk-Jin
    • Journal of the Korean earth science society
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    • v.32 no.7
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    • pp.732-749
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    • 2011
  • In this study, 27-year (1979-2005) regional climate over the CORDEX East Asia domain was reproduced using a regional climate model, RegCM4, driven by HadGEM2-AO output, and the model's simulation skill was evaluated in terms of surface air temperature and precipitation. The RegCM4 reasonably simulated the spatial distribution and interannual variability and seasonal variability of surface air temperature, while it had systematic biases in the simulation of precipitation. In particular, simulated rainband of East Asian summer monsoon was southward shifted below $30^{\circ}N$ as compared with the observation, thereby, summer mean precipitation over South Korea was significantly underestimated. Simulated temperature from the RegCM4 driven by the HadGEM2-AO output was comparable to that driven by the reanalysis. However, the RegCM4 driven by the HadGEM2-AO had prominently poor skill in the simulation of precipitation. This can be associated with the distorted monsoon circulations in the driving data (i.e., HadGEM2-AO) such as southward shifted low-level southwesterly, which resulted in the erroneous evolution of East Asian summer monsoon simulated by RegCM4.

Tc-99m Labeling of Dione Bisoxime Compounds (Dione Bisoxime 계통의 화합물에 대한 테크네슘표지 원리에 관한 연구)

  • Jeong, Jae-Min;Cho, Jung-Hyuk;Oh, Seung-Joon;Lee, Myung-Chul;Chung, Soo-Wook;Chung, June-Key;Lee, Dong-Soo;Kwark, Cheol-Eun;Lee, Kyung-Han;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.1
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    • pp.110-117
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    • 1995
  • Tc-99m Labeled hexamethylenepropyleneamineoxime ([$^{99m}Tc$]-HMPAO) is a famous amino-oxime compound and is widely used to construct SPECT images of cerebral blood flow. To investigate the relationship between chemical structure and radiolabeling in these kind of diamine-oxime compounds, we synthesized seven compounds by Schiff's base formation and successive reduction with sodium borohydride. They were (RR/SS )-4,8-diaza-3,6,6,9-tetramethylundecane-2,10-dione bisoxime (2), (RR/SS/meso)-4,8-diaza-3,9-dimethy-lundecane-2,10-dione bisoxime (4), (RR/SS/meso)-4,8-diaza-3,10-dimethyldodecane-2,11-dione bisoxime (5), (RR/SS/meso)-4,7-diaza-3,6,6,8-tetramethyldecane-2,9-dione bisoxime (8), (RR/SS/meso)-4,7-diaza-5,6-cyclohexyl-3,8-dimethyldecane-2,9-dione bisoxime (10), (RR/SS/meso)-3,4-bis(1-aza-2-methyl-3-oxime-1-butyl)-benzoic acid (12), and (RR/SS/ meso)-2,3-bis(1-aza-2-methyl-3-oxime-1-butyl) benzophenone (14). Chemical structures of all the synthesized compounds were identified by taking $^1H$ spectrum. Among them, 2 and 4 are propyleneamine oxime (PnAO), 6 is butyleneamine oxime (BnAO) and 8, 10, 12 and 14 are ethyleneamine oxime (EnAO). Each compound (0.5 mg) was incubated with stannous chloride (0.5 g - 8 g), carbonate-bicarbonate buffer (final concentration = 0.1 M, pH 7 - pH 10) and Tc-99m-pertechenate (1 ml). Tc-99m labeling of these compounds were checked by ITLC (acetone), ITLC (normal saline), reverse phase TLC (50 % acetonitrile) and ITLC (ethyl acetate). According to the results, EnAO's were not labeled by Tc-99m in any of above condition. About 11 % of maximum labeling efficiency was obtained with BnAO. However, 4 (PnAO) was labeled with Tc-99m to 85 % which is similar to the labeling efficiency of 2 (HMPAO). Hydrophilic impurity (9 % ) was the most significant problem with the labeling of 4, however, pertechnetate (3 % ) and colloid (3 %) were minor problem. In conclusion, we synthesized seven diamine blsoxlme compounds. Among them, four EnAO compounds were not labeled by Tc-99m. A BnAO was labeled poorly and two PnAO's were labeled well. These labeling can be explained by tertiary structure of their Tc-99m chelate.

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Treatment of the Acromioclavicular Joint Dislocation Using a AO Hook Plate (AO Hook 금속판을 이용한 견봉쇄골 관절 탈구의 치료)

  • Lee, Ki-Won;Choi, Young-Joon;Ahn, Hyung-Sun;Kim, Chung-Hwan;Hwang, Jae-Kwang;Han, Hee-Don;Kim, Jae-Hyoun;Joo, Youn-Suk
    • Clinics in Shoulder and Elbow
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    • v.12 no.2
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    • pp.167-172
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    • 2009
  • Purpose: We wanted to evaluate the results of treating acromioclavicular joint dislocation using an AO hook plate. Materials and Methods: Between February 2008 and September 2009, 10 patients underwent implant removal after surgical treatment of acromioclavicular joint dislocation using a AO hook plate. The Constant-Murley scoring system was administered postoperatively for evaluating the clinical results, and simple X-ray was taken for evaluating the state of reduction. Results: All cases showed satisfactory results on the clinical and radiological study. The mean Constant-Murley score at follow-up was 90.5 (range: 84~95). Three patients had some degree of discomfort with the hook plate, but these symptoms were relieved on removal of the plate. The radiological evaluation showed restoration of the vertical displacement of the clavicle in all the patients. No complications occurred such as infection, plate failure or redislocation after removal of the plate. Conclusion: The short term follow-up results of treating acromioclvicular joint dislocation using an AO hook plate were satisfactory both clinically and radiologically.

Clinicopathological characteristics of extrahepatic biliary neuroendocrine neoplasms in the gallbladder, extrahepatic biliary tract, and ampulla of Vater: A single-center cross-sectional study

  • Young Mok Park;Hyung Il Seo;Byeong Gwan Noh;Suk Kim;Seung Baek Hong;Nam Kyung Lee;Dong Uk Kim;Sung Yong Han
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.4
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    • pp.380-387
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    • 2023
  • Backgrounds/Aims: In 2019, the grading and staging system for neuroendocrine neoplasms (NENs) was significantly changed. In this study, we report the clinicopathological characteristics and surgical outcomes of patients with extrahepatic biliary NENs who underwent curative resection with or without adjuvant treatment. Methods: We retrospectively reviewed a database of 16 patients who developed NENs, neuroendocrine carcinoma (NEC), and mixed endocrine non-endocrine neoplasms (MiNENs) after curative resection. Among them, eight patients had ampulla of Vater (AoV) tumors, and eight patients had non-AoV tumors. Results: G1 and G2 were more frequently observed in the AoV group than in the non-AoV group (12.5% and 62.5%, respectively). In contrast, NEC and MiNEN were more common in the non-AoV group (50.0%). High Ki-67 index (> 20%) and perineural invasion (PNI) were more frequently observed in the non-AoV group. Advanced age (> 65 years), mitotic count > 20 per 2 mm2, and Ki-67 index > 20% were strongly correlated with patient survival (p = 0.018, 0.009, and 0.044, respectively). Advanced age (> 65 years) and mitotic count > 20 per 2 mm2 were significantly correlated with disease recurrence (p = 0.033 and 0.010, respectively). Conclusions: AoV and non-AoV tumors had significant differences in the histologic grade, Ki67, and PNI. Patients with non-AoV tumors had an increased risk for survival and recurrence than those in the AoV group. For extrahepatic biliary NENs, early detection of tumors, adequate surgery, and aggressive adjuvant treatment for high-risk patients are important to achieve long-term survival and prevent disease recurrence.

AoA Localization System based on Zigbee Experimentation and Realization (Zigbee 기반 AoA 위치인식 시스템 실험 및 구현)

  • Cho, Ho-Seong;Park, Chul-Young;Park, Dae-Heon;Park, Jang-Woo
    • Journal of Advanced Navigation Technology
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    • v.15 no.1
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    • pp.83-90
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    • 2011
  • The technique of localization is the core technology for information exchange or environment monitering to measure the position of an object or person. Today, the techniques of localization have been studied extensively and it can be applied to logistics, medical, robotics, etc. But, a lot of money to apply technique of localization is needed. Hence in this paper, we proposed AoA localization system based on Zigbee at low cost. The System measured the RSSI value by rotating the directional antenna using a step motor and Zigbee module. When the measured RSSI is the largest, the receiver measures the angles from beacons which are located at the corners with the rotating angle of a stepping motor and the position of the receiver will be calculated by appling AoA localization method. The measured results show an error about 35~36 cm.

Salt Effect on Interaction between Acridine Orange and Aerosol OT (Acridine Orange와 Aerosol OT 사이의 상호작용에 관한 염효과의 연구)

  • Song, Ki-Dong;Kim, Sung-Hyun
    • Applied Chemistry for Engineering
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    • v.7 no.1
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    • pp.83-90
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    • 1996
  • The changing shape of absorption and fluorescence spectra will increasing S/D in AO-AOT system decreases and then increases again. The aggregation and disaggreation in AO-AOT system occurres. According to increasing temperature, the absorbance increases in pure AO system. But it gradually decreases in premicellar range(S/D = 10, 20, 50 and 80). The disappearance degree of metachromasy according to the concentration of added salt to AO-AOT system is increased. However, the case of $NaNO_3$is reversed. The order of disappearance degree of metachromasy on cationic salts is $Li^+$, $Na^+$ > $Mg^{2+}$ > $Ca^{2+}$, and the order of it on anionic salts is $Cl^-$ > $SO_4{^{2-}}$ > $NO_3{^-}$.

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Abdominal Obesity and Associated Factors in the Elderly with a Focus on Health Habits, Mental Health, Chronic Diseases, and the Nutrient Intake Status: Data from the 2014 Korea National Health and Nutrition Examination Survey (우리나라 노인의 복부비만과 관련 요인 - 생활습관, 정신건강, 질환 및 영양소섭취 상태 중심으로: 2014 국민건강영양조사 자료 -)

  • Lee, Hye-Sang
    • Journal of the Korean Dietetic Association
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    • v.26 no.1
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    • pp.42-53
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    • 2020
  • The relationship of abdominal obesity ("AO") with co-morbidity and mortality is well established. This study assessed the factors associated with AO, which was defined as a waist circumference ≥90 cm for men and ≥85 cm for women, in the group aged over 65 years. A total of 1,435 subjects were analyzed among the participants of the 2014 Korean National Health and Nutrition Examination Survey. Statistical methods for a complex sample were applied by using a SPSS program (ver. 25.0). AO was more frequently found in females. The results of the logistic regression analysis showed that heavy drinking (OR: 1.53), no weight training (OR: 0.68), stressful mental status (OR: 0.61), bad health-related quality of life (by EQ_5D, OR: 1.45), hypertension (OR: 2.18), prediabetes (OR: 1.94), diabetes (OR: 1.63), low HDL-cholesterol (OR: 1.86), anemia (OR: 0.55), and heavy energy intake (OR: 1.41) were significantly related with the prevalence of AO after adjustment for gender. Heavy drinking (OR: 1.89), bad self-rating of health status (OR: 1.72), low HDL-cholesterol (OR: 1.85), heavy energy intake (OR: 1.79), low intake of riboflavin (OR: 1.60) were still significantly related with the prevalence of AO after adjustment for gender and body mass index (BMI), this study suggests that certain characteristics of health habits, mental health status, and chronic diseases may be associated with AO. This study did not establish the existence of relationship between nutrient intakes, except for riboflavin, and risk of AO, but this study suggests that prospective research is needed to establish causal connections among those factors.

Discrimination of Korean Apple Cultivars Using Combination of RAPD-SCAR Markers (RAPD-SCAR 마커 조합을 이용한 국내 육성 사과 품종 판별)

  • Cho, Kang-Hee;Heo, Seong;Kim, Hyun-Ran;Kim, Jeong-Hee;Shin, Il-Sheob;Han, Sang-Eun;Kim, Se-Hee;Kim, Dae-Hyun
    • Horticultural Science & Technology
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    • v.28 no.5
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    • pp.828-835
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    • 2010
  • Conventional methods for identification of apple cultivars are based on the evaluation of sets of morphological characteristics, however, closely related cultivars often cannot be distinguished by morphological traits. This study was conducted to develop DNA markers for discrimination of the apple cultivars bred in Korea. Thirty random primers generated eighty-three random amplified polymorphic DNA (RAPD) markers from thirty-one Korean bred and introduced apple cultivars. Fifty-two RAPD fragments were cloned and sequenced for conversion into sequence characterized amplified region (SCAR) markers. Among them only seventeen SCAR markers resulted in the amplification of single major bands the same size as the RAPD fragment cloned. Several combinations of six (AN11_433, AN08_566, A408_592, AK17_653, AO04_711, AO04_779 or AW15_368, AN11_433, A408_592, AK17_653, AO04_711, AO04_779, or AL1_427, AN11_433, AN08_566, A408_592, AK17_653, AO04_779) to seven (AL1_427, AN11_433, AN08_566, A408_592, AK17_653, AM16_708, AO04_779 or A330_424, AN11_433, AG14_502, AN08_566, A408_592, AK17_653, AO04_779 or A330_424, AN11_433, AK14_564, A408_592, AK17_653, AM16_708, AT14_789) SCAR markers provided enough polymorphism to identify sixteen Korean apple cultivars among thirty-one tested cultivars. Therefore, application of the seventeen SCAR markers was sufficient to identify the thirty-one tested apple cultivars. These markers could be utilized as a reliable tool for cultivar discrimination of Korean apples.

Treatment of Anterior Glenoid Rim Fracture with Comminuted Fragment Using Arthroscopic Reduction and AO Headless Compression Screw Fixation - A Case Report - (관절경하 AO 무두 압박 나사를 이용한 견갑골 전방 관절와 분쇄 골절의 치료 - 증례 보고 -)

  • Kim, Hyung-Sik;Koh, Il-Hyun;Kim, Sung-Guk;Chun, Yong-Min;Kim, Sung-Jae;Kang, Ho-Jung
    • Clinics in Shoulder and Elbow
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    • v.14 no.1
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    • pp.94-98
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    • 2011
  • Purpose: We present a case of anterior glenoid rim comminuted fracture that was treated with arthroscopic reduction and an AO headless compression screw (HCS) fixation. Materials and Methods: A 31-year old man complained of left shoulder pain after falling down on stairs. The anterior glenoid comminuted fragments were arthroscopically reduced. Fixation with an AO HCS was done after placement of 1.1 mm Kirschner wire as a guide pin through a standard cannulated anterosuperior portal. Results: Twelve months after the operation, union of the fracture was achieved and the range of motion was fully recovered. He did not complain of any discomfort during his activities of daily living. Conclusion: An AO HCS had various screw sizes and this was good for fixation of a small glenoid fracture and a long drill bit and screw driver were useful for fixation of deep seated glenoid fracture. A short guide wire could be replaced by a 1.1 mm K-wire. An AO HCS was useful for fixation of an anterior glenoid rim comminuted fracture.

Carrier Frequency Offset and 2-D AoA Estimation Method for an OFDM-based Mobile Relay Station with Uniform Circular Array (등간격 원형 어레이를 갖는 OFDM 기반의 이동 릴레이를 위한 반송파 주파수 옵셋 및 2-D 입사각 추정 기법)

  • Ko, Yo-Han;Cho, Yong-Soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.5A
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    • pp.423-431
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    • 2011
  • In this paper, carrier frequency offset and 2-D AoA (Angle-of-Arrival) estimation methods are proposed for an OFDM-based MRS (Mobile Relay Station) with UCA (Uniform Circular Array). The proposed methods are performed by using the preamble symbol in downlink and can improve the performance of CFO estimation significantly, compared with the conventional method. The proposed methods can be divided into two methods (method 1 and method 2) depending on the order of the AoA estimation and CFO estimation. It is shown by computer simulation under Mobile WiMAX environments that the proposed methods can estimate the CFOs and AoAs of adjacent BSs effectively.