• Title/Summary/Keyword: AIV

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Design of a CubeSat test platform for the verification of small electric propulsion systems

  • Corpino, Sabrina;Stesina, Fabrizio;Saccoccia, Giorgio;Calvi, Daniele
    • Advances in aircraft and spacecraft science
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    • v.6 no.5
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    • pp.427-442
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    • 2019
  • Small satellites represent an emerging opportunity to realize a wide range of space missions at lower cost and faster delivery, compared to traditional spacecraft. However, small platforms, such as CubeSats, shall increase their actual capabilities. Miniaturized electric propulsion systems can provide the satellite with the key capability of moving in space. The level of readiness of miniaturized electric propulsion systems is low although many concepts have been developed. The present research intends to build a flexible test platform for the assessment of selected small propulsion systems in relevant environment at laboratory level. Main goal of the research is to analyze the mechanical, electrical, magnetic, and chemical interactions of propulsion systems with the modern CubeSat-technology and to assess the performance of the integrated platform. The test platform is a 6U CubeSat hosting electric propulsion systems, providing mechanical, electrical and data interfaces, able to handle a variety of electric propulsion systems, thanks to the ability to regulate and distribute electric power, to exchange data according to several protocols, and to provide different mechanical layouts. The test platform is ready to start the first verification campaign. The paper describes the detailed design of the platform and the main results of the AIV activities.

Current situation and control strategies of H9N2 avian influenza in South Korea

  • Mingeun Sagong;Kwang-Nyeong Lee;Eun-Kyoung Lee;Hyunmi Kang;Young Ki Choi;Youn-Jeong Lee
    • Journal of Veterinary Science
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    • v.24 no.1
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    • pp.5.1-5.16
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    • 2023
  • The H9N2 avian influenza (AI) has become endemic in poultry in many countries since the 1990s, which has caused considerable economic losses in the poultry industry. Considering the long history of the low pathogenicity H9N2 AI in many countries, once H9N2 AI is introduced, it is more difficult to eradicate than high pathogenicity AI. Various preventive measures and strategies, including vaccination and active national surveillance, have been used to control the Y439 lineage of H9N2 AI in South Korea, but it took a long time for the H9N2 virus to disappear from the fields. By contrast, the novel Y280 lineage of H9N2 AI was introduced in June 2020 and has spread nationwide. This study reviews the history, genetic and pathogenic characteristics, and control strategies for Korean H9N2 AI. This review may provide some clues for establishing control strategies for endemic AIV and a newly introduced Y280 lineage of H9N2 AI in South Korea.

SPF 닭에서 재조합 H9N3 조류 인플루엔자 백신의 효능과 안전성 평가

  • Sin, Jeong-Hwa;Mo, In-Pil
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 2006.11a
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    • pp.90-91
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    • 2006
  • To reduce the economic impact and control Low pathogenic avian influenza (LPAI), vaccination with inactivated vaccine has been considered in this country. We tried to develop inactivated vaccine with reassorted H9N3 AI virus which has different type of neuraminidase compare to those of field AI virus. Before reassorted vaccine was produced, we confirm the virus as master seed by limiting dilution, RT-PCR and sequencing method. Also, we evaluate the biological characteristics of the virus to find out the possibility of prevention against field infection of AI virus. Finally, we evaluate the safety and efficacy of the vaccine made of reassorted AI virus in the specific pathogen free (SPF) chickens. After limiting dilution, we choose RV7CE4 as a vaccine candidate and compare the gene sequence of this vaccine strain to those of AI05GA which is parents strain. Compared to amino acid sequences of specific gene of AI05GA and RV7CE4, exhibited a high degree of amino acid sequence homology. In the safety and efficacy test, there were no specific clinical signs or mortality. Reassorted H9N3 viruses were reisolated in cloaca swab on 5 days post inoculation. In the vaccine study, once or twice vaccination was performed and challenged with H9N2 field virus (01310). Vaccine has no adverse effect on birds and formed good immune capability which reduce viral shedding in the birds infected with 01310. Based on the above result, we developed reassorted H9N3 vaccine which will efficiently prevent the low pathogenic AIV (H9N2) infection in the poultry farms.

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An Analysis of Aerosols Impacts on the Vertical Invigoration of Continental Stratiform Clouds (에어로솔의 대륙 층운형 구름 연직발달(Invigoration)에 미치는 영향 분석)

  • Kim, Yoo-Jun;Han, Sang-Ok;Lee, Chulkyu;Lee, Seoung-Soo;Kim, Byung-Gon
    • Atmosphere
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    • v.23 no.3
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    • pp.321-329
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    • 2013
  • This study examines the effect of aerosols on the vertical invigoration of continental stratiform clouds, using a dataset of Atmospheric Radiation Measurement (ARM) Intensive Operational Period (IOP, March 2000) at the Southern Great Plains (SGP) site. To provide further support to our observation-based findings, the weather research and forecasting (WRF) sensitivity simulations with changing cloud condensation nuclei (CCN) concentrations have been carried out for the golden episode over SGP. First, cross correlation between observed aerosol scattering coefficient and cloud liquid water path (LWP) with a 160-minutes lag is the highest of r = 0.83 for the selected episode, which may be attributable to cloud vertical invigoration induced by an increase in aerosol loading. Modeled cloud fractions in a control run are well matched with the observation in the perspective of cloud morphology and lasting period. It is also found through a simple sensitivity with a change in CCN that aerosol invigoration (AIV) effect on stratiform cloud organization is attributable to a change in the cloud microphysics as well as dynamics such as the corresponding modification of cloud number concentrations, drop size, and latent heating rate, etc. This study suggests a possible cloud vertical invigoration even in the continental stratiform clouds due to aerosol enhancement in spite of a limited analysis based on a few observed continental cloud cases.

Evaluation of the disinfectant concentration used on livestock facilities in Korea during dual outbreak of foot and mouth disease and high pathogenic avian influenza

  • Kim, Seongjoon;Chung, Hansung;Lee, Hyesook;Myung, Donghoon;Choi, Kwanghoon;Kim, Sukwon;Htet, Swe Lynn;Jeong, Wooseog;Choe, Nonghoon
    • Journal of Veterinary Science
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    • v.21 no.3
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    • pp.34.1-34.10
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    • 2020
  • Background: A nationwide outbreak of foot-and-mouth disease (FMD) in South Korea caused massive economic losses in 2010. Since then, the Animal and Plant Quarantine Agency (QIA) has enhanced disinfection systems regarding livestock to prevent horizontal transmission of FMD and Avian influenza (AI). Although the amount of disinfectant used continues to increase, cases of FMD and AI have been occurring annually in Korea, except 2012 and 2013. Objectives: This study measured the concentration of the disinfectant to determine why it failed to remove the horizontal transmission despite increased disinfectant use. Methods: Surveys were conducted from February to May 2017, collecting 348 samples from disinfection systems. The samples were analyzed using the Standards of Animal Health Products analysis methods from QIA. Results: Twenty-three facilities used inappropriate or non-approved disinfectants. Nearly all sampled livestock farms and facilities-93.9%-did not properly adjust the disinfectant concentration. The percentage using low concentrations, or where no effective substance was detected, was 46.9%. Furthermore, 13 samples from the official disinfection station did not use effective disinfectant, and-among 72 samples from the disinfection station-88.89% were considered inappropriate concentration, according to the foot-and-mouth disease virus guidelines; considering the AIV guideline, 73.61% were inappropriate concentrations. Inappropriate concentration samples on automatic (90.00%) and semi-automatic (90.90%) disinfection systems showed no significant difference from manual methods (88.24%). Despite this study being conducted during the crisis level, most disinfectants were used inappropriately. Conclusions: This may partially explain why horizontal transmission of FMD and AI cannot be effectively prevented despite extensive disinfectant use.

Numerical investigation on the flow noise reduction due to curved pipe based on wavenumber-frequency analysis in pressure relief valve pipe system (감압 밸브 배관 시스템 내 파수-주파수 분석을 통한 곡관의 유동소음 저감에 대한 수치적 연구)

  • Garam, Ku;Cheolung, Cheong
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.6
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    • pp.705-712
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    • 2022
  • A sudden pressure drop caused by the pressure relief valve acts as a strong noise source and propagates the compressible pressure fluctuation along the pipe wall, which becomes a excitation source of Acoustic Induced Vibration (AIV). Therefore, in this study, the numerical methodology is developed to evaluate the reduction effect of compressible pressure fluctuation due to curved pipe in the pressure relief valve system. To describe the acoustic wave caused by density fluctuation, unsteady compressible Large Eddy Simulation (LES) technique, which is high accuracy numerical method, Smagorinsky-Lilly subgrid scale model is applied. Wavenumber-frequency analysis is performed to extract the compressible pressure fluctuation component, which is propagated along the pipe, from the flow field, and it is based on the wall pressure on the upstream and downstream pipe from the curved pipe. It is shown that the plane wave and the 1st mode component in radial direction are dominant along the downstream direction, and the overall acoustic power was reduced by 3 dB through the curved pipe. From these results, the noise reduction effect caused by curved pipe is confirmed.

Monitoring of Major Viral Pathogen Contamination in New and Reused Broiler Farm Litter (육계 농장 깔짚에서의 주요 바이러스 병원체 오염 실태 조사)

  • Choi, Kang-Seuk;Jeon, Woo-Jin;Lee, Eun-Kyoung;Kwon, Jun-Hun;Lee, Jin-Hwa;Sung, Haan-Woo
    • Korean Journal of Poultry Science
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    • v.38 no.3
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    • pp.181-189
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    • 2011
  • A 5-month (May to November in 2009) monitoring program for five viral pathogens in litter, such as avian influenza virus A (AIV), infectious bronchitis virus (IBV), infectious bursal disease virus (IBDV), fowl adenovirus (FAdV), and chicken infectious anemia virus (CIAV) was conducted in 62 flocks at 31 broiler farms (two flocks in each farm) in Korea in 2009. Viral pathogens were examined twice (before and at the end of the rearing period) at 31 broiler farms, and included fresh litter (n = 16) and recycled litter (n = 15) farms. Thirty-seven viruses (14 IBVs, 2 IBDVs, 9 FAdVs, and 12 CIAVs) were isolated from 75% (12/16) and 73% (11/15) of fresh litter and reused litter farms during the period, respectively, indicating no difference in viral contamination rate between farms using new and reused litter. Of these isolates, three (two CIAVs and one IBDV) were isolated from recycled litter samples collected before the rearing period at three broiler farms, whereas the others (n=34) were isolated from fresh and recycled litter samples collected at the end of the rearing period. When the performances, involving viability, body weight, and feed conversion ratio, were compared, no significant differences were found between farms using fresh and recycled litter during the period.

Novel reassortant 2.3.4.4B H5N6 highly pathogenic avian influenza viruses circulating among wild, domestic birds in Xinjiang, Northwest China

  • Zhang, Qian;Mei, Xindi;Zhang, Cheng;Li, Juan;Chang, Nana;Aji, Dilihuma;Shi, Weifeng;Bi, Yuhai;Ma, Zhenghai
    • Journal of Veterinary Science
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    • v.22 no.4
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    • pp.43.1-43.10
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    • 2021
  • Background: The H5 avian influenza viruses (AIVs) of clade 2.3.4.4 circulate in wild and domestic birds worldwide. In 2017, nine strains of H5N6 AIVs were isolated from aquatic poultry in Xinjiang, Northwest China. Objectives: This study aimed to analyze the origin, reassortment, and mutations of the AIV isolates. Methods: AIVs were isolated from oropharyngeal and cloacal swabs of poultry. Identification was accomplished by inoculating isolates into embryonated chicken eggs and performing hemagglutination tests and reverse transcription polymerase chain reaction (RT-PCR). The viral genomes were amplified with RT-PCR and then sequenced. The sequence alignment, phylogenetic, and molecular characteristic analyses were performed by using bioinformatic software. Results: Nine isolates originated from the same ancestor. The viral HA gene belonged to clade 2.3.4.4B, while the NA gene had a close phylogenetic relationship with the 2.3.4.4C H5N6 highly pathogenic avian influenza viruses (HPAIVs) isolated from shoveler ducks in Ningxia in 2015. The NP gene was grouped into an independent subcluster within the 2.3.4.4B H5N8 AIVs, and the remaining six genes all had close phylogenetic relationships with the 2.3.4.4B H5N8 HPAIVs isolated from the wild birds in China, Egypt, Uganda, Cameroon, and India in 2016-2017, Multiple basic amino acid residues associated with HPAIVs were located adjacent to the cleavage site of the HA protein. The nine isolates comprised reassortant 2.3.4.4B HPAIVs originating from 2.3.4.4B H5N8 and 2.3.4.4C H5N6 viruses in wild birds. Conclusions: These results suggest that the Northern Tianshan Mountain wetlands in Xinjiang may have a key role in AIVs disseminating from Central China to the Eurasian continent and East African.

Genetic Characterization of H7-subtype Avian Influenza Viruses (H7 아형 조류인플루엔자 바이러스의 유전자 특성)

  • Yeo, Jiin;Kwon, Hyuk-Moo;Sung, Haan-Woo
    • Korean Journal of Poultry Science
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    • v.46 no.3
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    • pp.173-183
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    • 2019
  • Based on their virulence, the avian influenza viruses (AIVs) are classified into two pathotypes: low pathogenic avian influenza (LPAI) virus and highly pathogenic avian influenza (HPAI) virus. Among the 16 HA subtypes of AIV, only the H5 and H7 subtypes are classified as HPAI. Some AIVs, including H5 and H7 viruses, can infect humans directly. Six H7 subtype isolates from wild birds of the H7N7 (n=4) and H7N1 (n=2) subtypes were characterized in this study. Phylogenetic analysis showed that eight viral genes (HA, NA, PB2, PB1, PA, NP, M, and NS) of the H7 isolates clustered in the Eurasian lineage, the genetic diversity of which is indicated by its division into several sublineages. The Korean H7 isolates had two motifs, PEIPKGR and PELPKGR, at the HA cleavage site, which have been associated with LPAI viruses. Six H7 isolates encoded glutamine (Q) and glycine (G) at positions 226 (H3 numbering) and 228 of HA, suggesting avian-type receptor-binding specificity. None of the Korean H7 isolates had the amino acid substitutions E627K in PB2 and I368V in PB1, which are critical for efficient replication in human cells. The Korean H7 isolates showed no deletions in the NA stalk region and in NS. These results suggest that the Korean H7 isolates from wild birds are different from the H7N9 influenza viruses isolated in China in 2013, which are capable of infecting humans.