• Title/Summary/Keyword: AICD

검색결과 152건 처리시간 0.023초

유기산 혼합물 및 돈사폐수를 이용한 Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate)의 생산 (Production of Biodegradable Plastics, Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate) from Organic Aicd Mixtures and Swine Waste)

  • 박창호
    • KSBB Journal
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    • 제13권5호
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    • pp.615-620
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    • 1998
  • The readily fermentable carbon sources in swine were acetic acid, propionic acid and butyric acid at the average concentrations of 7.2 g/L, 2.2 g/L and 2.7 g/L, respectively. The swine waste also contained excess nitrogen and other mineral sources. In shake flask experiments, the optimal range of cell growth for Azotobacter vinelandii UWD were 1.0∼3.5 g/L of acetic acid, 0.7∼2.0 g/L of propionic acid and 0.5∼2.0 g/L of butyric acid. A mixture of these three acids simulating two times diluted swine waste supported the best cell growth but the amount of carbon sources was limited. In shake flask and fermentor experiments, an addition of 30 g/L of glucose increased the final cell dry weight 8 times while the final poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) concentration increased 86 times compared with using acid mixture only. A. vinelandii UWD preferred organic acids in the sequence of acetic acid, propionic acid, butyric acid, and valeric acid.

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강원도산 잡화벌꿀의 유기산 및 지방산 특성에 관한 연구 (Organic Acids and Fatty Acids of Honey Harvested in Kangwon Area)

  • 김복남;김택제;최홍식
    • 한국식품영양과학회지
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    • 제20권1호
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    • pp.52-58
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    • 1991
  • Physico-chemical properties including the composition of organic acids and fatty acids in native bee-honey and foreign bee-honey harvested in Kangwon area were studied with the emphasis on the honey which was collected form wild flowers nd mixed flowers sources for honey nectars. the major organic acids were considered as acetic acid formic acid and valeric acid in volatile acids and gluconic acid maleic acid malic acid quinic acid and citric acid in non-volatile fraction in both of native bee-honey and foreigr bee-honey. Some naturally occuring fatty acids({{{{ { C}_14{ } }}}}-{{{{ {C }_{20 } }}}}) were observed with the principal fatty acids of myristic aicd linolenic acid and palmitic acid and palmitic acid in the various honey, The characteristics of moisture content pH viscosity free acidity lactone and total acidity were also analyzed and discussed.

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Epigenetic modification is linked to Alzheimer's disease: is it a maker or a marker?

  • Lee, Jung-Hee;Ryu, Hoon
    • BMB Reports
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    • 제43권10호
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    • pp.649-655
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    • 2010
  • Alzheimer's disease (AD) is the most common age-dependent neurodegenerative disorder and shows progressive memory loss and cognitive decline. Intraneuronal filaments composed of aggregated hyperphosphorylated tau protein, called neurofibrillary tangles, along with extracellular accumulations of amyloid $\beta$ protein (A$\beta$), called senile plaques, are known to be the neuropathological hallmarks of AD. In light of recent studies, epigenetic modification has emerged as one of the pathogenic mechanisms of AD. Epigenetic changes encompass an array of molecular modifications to both DNA and chromatin, including transcription factors and cofactors. In this review, we summarize how DNA methylation and changes to DNA chromatin packaging by post-translational histone modification are involved in AD. In addition, we describe the role of SIRTs, histone deacetylases, and the effect of SIRT-modulating drugs on AD. Lastly, we discuss how amyloid precursor protein (APP) intracellular domain (AICD) regulates neuronal transcription. Our understanding of the epigenomes and transcriptomes of AD may warrant future identification of novel biological markers and beneficial therapeutic targets for AD.

Chlorella 엽록체의 인지질 생합성 및 지방산조성에 미치는 Nitrate와 Phosphate 결핍효과 (Effects of the Nitrate and Phosphate Starvation on the Biosynthesis of Phospholipid and the Composition of Fatty Acids in Chlorella Chloroplasts)

  • 이점규
    • Journal of Plant Biology
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    • 제31권3호
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    • pp.187-196
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    • 1988
  • Chlorella ellipsoidea were cultured in "cold" media starvated with the nitrate and phsophate sources. The effects of the nitrate and phsophate starvation on the biosynthesis of phospholipid and the composition of fatty acids in chloroplasts isolated from these cells were analyzed. The syntheses of phosphatidylcholine and phosphatidylinositol in the nitrate and phosphate starvation were similarly inhibited as compared with the control but phsophatidylethanolamine synthesis in the nitrate starvation was extremely lower than that in the phosphate starvation. The major fatty acids utilized in phospholipid formation within chloroplasts were palmitic acid and linolenic aicd. However, palmitic acid and stearic acid were dominant in the condition of the nitrate starvation. The levels of palmitic acid were enhanced 3-fold than that of the control. These results suggest that the biosynthesis of phospholipid and the composition of fatty acids were affected by the nitrate and phosphate starvation in the culture media.ure media.

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Cymbidium spp.의 Protocorm 묘조 분화시 Protocorm내 전분 함량에 미치는 $GA_3$와 ABA의 영향 (Effects of $GA_3$ and ABA on Endogenous Starch Content during Shoot Differentiation in Cymbidium spp. Protocorm)

  • 한태진
    • Journal of Plant Biology
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    • 제31권4호
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    • pp.249-258
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    • 1988
  • Changes in starch content and activities of ADPG- and UDPG-starch synthase and $\alpha$- and, $\beta$-amylase were studied in order to investigate effects of gibberellic aicd and abscisic acid on endogenous starch content during shoot differentiation and protocorm propagation in Cymbidium spp. (Jungfrau) protocorm. Shoot differentiation was promoted during the degradation of endogenous starch and protocorn propagation was promoted during starch accumulation in protocorm. The activities of ADPG- and, UDPG-starch synthase and $\alpha$- and $\beta$-amylase seemed to be related with starch content. Shoot differentiation and protocorm propagation were slightly inhibited in protocorm explants treated with 100$\mu$M gibberellic acid. The explants treated with 10$\mu$M abscisic acid lost the capacity for shoot differentiation and protocorm propagation, and that could not be overcome by 100$\mu$M gibberellic acid added to culture medium. Starch content fluctuated as the control even after 10$\mu$M abscisic acid. None the less, the treatment completely inhibited shoot differentiation and protocorm propagation.

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강낭콩 하배축 절편의 부정근형성에 미치는 내재 IAA의 이동 (Effect of Endogenous IAA Transport on Adventitious Root Formation in Phaseolus vulgaris Hypocotyl Cuttings)

  • 조덕이
    • Journal of Plant Biology
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    • 제32권4호
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    • pp.323-330
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    • 1989
  • This work was carried out to elucidate effects of endogenous and exogenous IAA transport on adventitious root formation in Phaseolus vulgaris hypocotyl cuttings. For inverted or normal incubation in distilled water, the adventitious root is always formed at the morphological base but not at the morphological apex. For inverted incubation, in both distilled water and certain chemical solution, the root formation is retarded more at the first stage (0-24 hr) than at the second stage (24-48 hr). When p-chlorophenoxyisobutyric acid (PCIB) was applied to the cuttings at the first stage, theroot formation was inhibited more than at the second stage. Treatment of 2,3,5-triiodobenzoic aicd (TIBA)markedly inhibited the adventitious root formation in Phaseolus vulgaris hypocotyl cuttings. This inhibition influenced the root according to the applied stage and period. Therefore, the root formation is more related to the stage of root primordium formation than to the stage of root elongation from the primordium. Inhibition of auxin transport oraction by TIBA or PCIB could also be reversed when hypocotyl cuttings are incubated in exogenously applied IAA solution.

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전자빔 가속기를 이용한 폴리프로필렌 섬유의 개질(I) - 전자빔 조사에 따른 폴리프로필렌 섬유의 물리적, 열적 특성변화 - (Electron Beam -Induced Graft Polymerization of Acrylic Aicd on Polypropylene Nonwoven Fabrics(I))

  • 김홍제;;임용진;이기풍
    • 한국염색가공학회지
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    • 제15권2호
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    • pp.102-108
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    • 2003
  • Before studying graft polymerization of PP(polypropylene) nonwoven fabrics by electron beam preirradiation method, mechanical properties, thermal properties and degree of crystallinity of original and electron beam irradiated PP nonwoven fabrics were investigated. Morphological surface changes of electron beam irradiated PP nonwoven fabrics were not observed. And the melting temperature and crystallinity of electron beam irradiated PP nonwoven fabrics also did not change as compared with untreated PP nonwoven fabrics. But the breaking strength of electron beam irradiated PP nonwoven fabrics decreased with increasing electron beam absorbed dose due to breakdown of some parts of polymer main chain.

Alcaligenes eutrophus phbCAB Operon의 재조합과 Poly-$\beta$-hydroxybutyric Aicd의 대장균내 축적 (Construction of the Recombinant phbCAB Operon of Alcaligenes eutvtrphus for Accumulation of Poly-$\beta$-hydroxybu tyric Acid in Escherichia coli)

  • 김경태;박진서;이용현;허태린;박해철
    • 한국미생물·생명공학회지
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    • 제21권3호
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    • pp.221-228
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    • 1993
  • In order to achieve poly-beta-hydroxybutyric acid (PHB) production using recombinant DNA in various host bacterial cells, the isolation of genes for PHB biosynthesis was attempted. As a result, a 5.2kb DNA fragment containing phbCAB operon of Alcaligenes eutrophus was isolated by colony hybridization using synthetic oligodeoxyribonucleotides as probes. The constructed recmbinant plasmid pSK(+)-phbCAB operon was transferred to Escherichia coli, and the obtained transformant accumulated considerable amount of PHB.

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양식산 넙치의 백화현상에 따른 아미노산 조성의 비교 (Comparison of Amino Acid by Appearance of Albinism in Cultured Flounder Paralichthys olivaceus)

  • 김종현
    • 한국식품영양학회지
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    • 제12권5호
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    • pp.496-501
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    • 1999
  • Albinism is a phenomenon that color of the body surface is changed to white orfaint brown from the specific color to the species by difficiency of pigments due to mutation or disease. This study was undertaken to investigate the experimental basis on the appearance of albinism in cultured flounder Paralichthys olivaceus. The skin and muscle from the normal and albinic flounder were used by measuring contents of amino acid free amino acid. The results were summarized as follows: Contents of amino acid in theskin and muscle are different from normal and albinic flounder. Phenolic and sulfuric amino acids in the skin of normal flounder were 2 times those of albinic ones. Especially tyrosine contents of the skin in normal flounder were 24 times higher than those. Methionine was 26 times higher than those Phenylalanine was 1.6 times higher. In free amino aicd phosphoserine and phosphoethanolamine were a little higher than that ones. The melanin formation of the skin in flounder was affected by substrates such as phenolic amino acid and cofactor such as sulfuric amino acid.

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돈피의 부위별 특성과 이화학적 성분분석

  • 전기홍;김영붕;양승용;이남혁;문윤선;박미선;장애라
    • 한국축산식품학회:학술대회논문집
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    • 한국축산식품학회 2005년도 제36차 추계 학술발표대회
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    • pp.107-110
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    • 2005
  • 돈피를 부위별로 분류하여 일반성분, 아미노산, 지방산, 색도, 조직감, 관능평가를 실시하였다. 일반성분은 등 부위를 제외한 부위들이 비슷한 수치를 보였고 아미노산은 앞다리 부위와 뒷다리 부위가 필수 아미노산 함유량이 더 높은 것으로 나타났다. 돈피의 지방산 함량은 부위에 따라서는 크게 차이가 나타나지 않았으며 지방산의 종류별로는 oleic aicd의 함량이 가장 많았고, 색도는 붉고 황색기가 적으며 명도가 높은 등 부위와 배 부위가 높은 수치를 보였고 이는 관능에 영향을 미쳐 명도가 낮고 붉은 황색을 띄는 앞다리보다 높은 기호도를 보였다.

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