• Title/Summary/Keyword: AH36

Search Result 474, Processing Time 0.03 seconds

Cytotoxicity and Genotoxicity of Newly Developed Calcium Phosphate-based Root Canal Sealers (신개발 인산칼슘계 근관 봉함재의 세포독성 및 유전독성에 관한 연구)

  • Kim, Hee-Jung;Baek, Seung-Ho;Bae, Kwang-Shik
    • Restorative Dentistry and Endodontics
    • /
    • v.31 no.1
    • /
    • pp.36-49
    • /
    • 2006
  • The purpose of this study was to compare the cytotoxicity by MTT test and genotoxicity by Ames test of new calcium phosphate-based root canal sealers (CAPSEAL I, CAPSEAL II) with commercially available resin-based sealers (AH 26, AH Plus) , zinc oxide eugenol-based sealers (Tubliseal EWT, Pulp Canal Sealer EWT), calcium hydroxide-based sealer (Sealapex), and tricalcium phosphate based sealers (Sankin Apatite Root Canal Sealer I, II, III). According to this study, the results were as follows : 1. The extracts of freshly mixed group showed higher toxicity than those of 24 h set group in MTT assay (p<0.001). 2. CAPSEAL I and CAPSEAL II were less cytotoxic than AH 26, AH Plus, Tubliseal EWT, Pulp Canal Sealer EWT Sealapex and SARCS II in freshly mixed group (p<0.01). 3. AH 26 in freshly mixed group showed mutagenicity to TA98 and TA100 with and without S9 mix and AH Plus extracts also were mutagenic to TA100 with and without S9 mix. 4. Tubliseal EWT, Pulp Canal Sealer EWT and Sealapex in freshly mixed group were mutagenic to TA100 with S9 mix. 5. Among those of 24 h set groups the extracts of SARCS II were mutagenic to TA98 with and without S9 mix and AH 26 showed mutagenic effects to TA98 with S9 mix. 6. No mutagenic effect of CAPSEAL I and CAPSEAL II was detected. 7. There is no statistically significant difference between CAPSEAL I and CAPSEAL II at MTT assay and Ames test in both freshly mixed group and 24 h set group.

Inhibitory Effect of Aged Petroleum Hydrocarbons on the Survival of Inoculated Microorganism in a Crude-Oil-Contaminated Site

  • Kang, Yoon-Suk;Park, Youn-Jong;Jung, Jae-Joon;Park, Woo-Jun
    • Journal of Microbiology and Biotechnology
    • /
    • v.19 no.12
    • /
    • pp.1672-1678
    • /
    • 2009
  • We studied the effects of aged total petroleum hydrocarbons (aged TPH) on the survival of allochthonous diesel-degrading Rhodococcus sp. strain YS-7 in both laboratory and field investigations. The aged TPH extracted from a crude-oil-contaminated site were fractionized by thin-layer chromatography/flame ionization detection (TLC/FID). The three fractions identified were saturated aliphatic (SA), aromatic hydrocarbon (AH), and asphaltene-resin (AR). The ratio and composition of the separated fractions in the aged TPH were quite different from the crude-oil fractions. In the aged TPH, the SA and AH fractions were reduced and the AR fraction was dramatically increased compared with crude oil. The SA and AH fractions (2 mg/l each) of the aged TPH inhibited the growth of strain YS-7. Unexpectedly, the AR fraction had no effect on the survival of strain YS-7. However, crude oil (1,000 mg/l) did not inhibit the growth of strain YS-7. When strain YS-7 was inoculated into an aged crude-oil-contaminated field and its presence was monitored by fluorescent in situ hybridization (FISH), we discovered that it had disappeared on 36 days after the inoculation. For the first time, this study has demonstrated that the SA and AH fractions in aged TPH are more toxic to an allochthonous diesel-degrading strain than the AR fraction.

Effect of Calcination Temperatures on the Structure and Electrochemical Characterization of Li(Ni0.5Mn0.3Co0.2)O2 as Cathode Material by Supercritical Hydrothermal Synthesis Method (초임계 수열법으로 합성한 Li(Ni0.5Mn0.3Co0.2)O2 양극 활물질의 소성 온도영향에 따른 구조 및 전기화학적 특성)

  • Choo, Soyeon;Beom, YunGyeong;Kim, Sungsu;Han, Kyooseung
    • Journal of the Korean Electrochemical Society
    • /
    • v.16 no.3
    • /
    • pp.151-156
    • /
    • 2013
  • As the cathode material for li-ion battery, $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$ were synthesized by supercritical hydrothermal method and calcined $850^{\circ}C$ and $900^{\circ}C$ for 10hrs in air. The effect of temperature in the heat treatment on the powder and its performance were studied of xray diffraction pattern, SEM-image, physical properties and electrochemical behaviors. As a result, calcined at $900^{\circ}C$ material particle size more increase than calcined at $850^{\circ}C$ material, especially shows excellent electrochemical performance with initial reversible specific capacity of 163.84 mAh/g (0.1C/2.0-4.3V), 186.87 mAh/g (0.1C/2.0-4.5V) and good capacity retention of 91.49% (0.2C/2.0-4.3V) and 90.36% (0.2C/2.0-4.5V) after 50th charge/discharge cycle.

Paricalcitol attenuates lipopolysaccharide-induced inflammation and apoptosis in proximal tubular cells through the prostaglandin E2 receptor EP4

  • Hong, Yu Ah;Yang, Keum Jin;Jung, So Young;Chang, Yoon Kyung;Park, Cheol Whee;Yang, Chul Woo;Kim, Suk Young;Hwang, Hyeon Seok
    • Kidney Research and Clinical Practice
    • /
    • v.36 no.2
    • /
    • pp.145-157
    • /
    • 2017
  • Background: Vitamin D is considered to exert a protective effect on various renal diseases but its underlying molecular mechanism remains poorly understood. This study aimed to determine whether paricalcitol attenuates inflammation and apoptosis during lipopolysaccharide (LPS)-induced renal proximal tubular cell injury through the prostaglandin $E_2$ ($PGE_2$) receptor EP4. Methods: Human renal tubular epithelial (HK-2) cells were pretreated with paricalcitol (2 ng/mL) for 1 hour and exposed to LPS ($1{\mu}g/mL$). The effects of paricalcitol pretreatment in relation to an EP4 blockade using AH-23848 or EP4 small interfering RNA (siRNA) were investigated. Results: The expression of cyclooxygenase-2, $PGE_2$, and EP4 were significantly increased in LPS-exposed HK-2 cells treated with paricalcitol compared with cells exposed to LPS only. Paricalcitol prevented cell death induced by LPS exposure, and the cotreatment of AH-23848 or EP4 siRNA offset these cell-protective effects. The phosphorylation and nuclear translocation of p65 nuclear factor-kappaB ($NF-{\kappa}B$) were decreased and the phosphorylation of Akt was increased in LPS-exposed cells with paricalcitol treatment. AH-23848 or EP4 siRNA inhibited the suppressive effects of paricalcitol on p65 $NF-{\kappa}B$ nuclear translocation and the activation of Akt. The production of proinflammatory cytokines and the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling-positive cells were attenuated by paricalcitol in LPS exposed HK-2 cells. The cotreatment with an EP4 antagonist abolished these anti-inflammatory and antiapoptotic effects. Conclusion: EP4 plays a pivotal role in anti-inflammatory and antiapoptotic effects through Akt and $NF-{\kappa}B$ signaling after paricalcitol pretreatment in LPS-induced renal proximal tubule cell injury.

Synthesis and Electrochemical Properties of Zn and Al added LiNi0.85Co0.15O2 Cathode Materials (Zn와 Al을 첨가한 LiNi0.85Co0.15O2 양극활물질의 제조 및 전기화학적 특성평가)

  • Kim, Su-Jin;Seo, Jin-Seong;Na, Byung-Ki
    • Korean Chemical Engineering Research
    • /
    • v.59 no.1
    • /
    • pp.42-48
    • /
    • 2021
  • Zn and Al added LiNi0.85Co0.15O2 cathode materials were synthesized to improve electrochemical properties and thermal stability using a solid-state route. Crystal structure, particle size and surface shape of the synthesized cathode materials was measured using XRD (X-ray diffraction) and SEM (scanning electron microscopy). CV (cyclic voltammetry), first charge-discharge profiles, rate capability, and cycle life were measured using battery cycler (Maccor, series 4000). Strong binding energy of Al-O bond enhanced structure stability of cathode material. Electrochemical properties were improved by preventing cation mixing between Li+ and Ni2+. Large ion radius of Zn+ increased lattice parameter of NC cathode material, which meant unit-cell volume was expanded. NCZA25 showed 80% of capacity retention at 0.5 C-rate during 100 cycles, which was 12% higher than that of NC cathode. The discharge capacity of NCZA25 showed 104 mAh/g at 5 C-rate. NCZA25 achieved 36 mAh/g more capacity than that of NC cathod. NCZA25 cathode material showed excellent rate capability and cycling performance.

A Study on the Cutting Phenomena in CNC Gas Cutting Under Various Cutting Conditions (고장력 강판의 CNC 가스 절단시 절단조건 변화에 따른 절단현상에 관한 연구)

  • 김성일
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
    • /
    • 2002.10a
    • /
    • pp.186-191
    • /
    • 2002
  • In the CNC gas cutting of steel plate, the cutting quality are strongly dependent on the various cutting conditions. The cutting tests of high tensile steel plate(AH36) were carried out using CNC gas cutting machine at various cutting conditions such as cutting speed, steel plate thickness, distance between tip and specimen etc. The kerf width and the surface roughness of cutting surfaces are examined. The photographs of cutting surface and cutting section are also analyzed.

  • PDF

Traumatic tension enterothorax in New Zealand: a case report

  • Monique Mahadik;Ashok Gunawardene;Aleisha Sutherland;Damien Ah Yen
    • Journal of Trauma and Injury
    • /
    • v.36 no.3
    • /
    • pp.258-260
    • /
    • 2023
  • Traumatic rupture of the right hemidiaphragm occurred following a high-velocity motor vehicle collision in the case presented herein. The resulting herniation of small bowel loops into the thorax resulted in hemodynamic and respiratory compromise due to pressure effects on the right heart and major vessels. The patient's hemodynamic status improved with reduction of enterothorax, and the diaphragmatic defect was repaired. We discuss the available literature and learning points from this rare case.

The Predictability of Emotional Labor Dimensions on Job Stress, Customer Orientation, and Job Satisfaction

  • Yoh, Eun-Ah
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.36 no.6
    • /
    • pp.601-615
    • /
    • 2012
  • In this study, two representative measures in the job-focused approach and the employee-focused approach of emotional labor are explored to examine dimensionality and the predictability of each emotional labor measure on key consequences that include job stress, customer orientation, and job satisfaction. Data obtained from 193 department store apparel saleswomen were submitted for analysis. The results show that the emotional dissonance and emotional effort of the Kruml and Geddes measure are good predictors for job stress, customer orientation, and job satisfaction. In a test of the Davies measure, job stress is predicted by emotional dissonance and frequency while customer orientation is predicted by duration, variety, and the frequency of emotional expression in jobs. Duration is also a key predictor for job satisfaction. The result confirm the dimensionality and predictability of two emotional labor measures as well as suggests the need for the careful selection and refinement of appropriate measures according to consequences.