• Title/Summary/Keyword: AGO

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묵사집산법의 하자

  • 류인영
    • Journal for History of Mathematics
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    • v.12 no.2
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    • pp.63-82
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    • 1999
  • The ways of mathematical meditative concentration of one's attentive calculation are the important records of the mathematics in the Korean mathematical history. Through them, we can find the methods of the mathematical thinking several generations ago, and presume the styles of life in the Chosun dynasty as men see the ancient life by the fossils. Thus we need to see them out of our unconcerns and rearrange them from the disorder without distortions.

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A Case of Extensive Polyostotic Fibrous Dysplasia (광범위하게 진행된 다발성 섬유성이형성증)

  • Lee Byeong-Do;Hwang Eui-Hwan;Lee Sang-Rae
    • Imaging Science in Dentistry
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    • v.30 no.2
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    • pp.117-122
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    • 2000
  • Fibrous dysplasia is a benign disorder of bone consisting of intramedullary proliferation of fibrous tissue and irregularly distributed, poorly developed bone. The disease manifests itself in the monostotic form in which only one bone is involved and the polyostotic form in which multiple bones at different sites are affected. We reported a extensive case of polyostotic fibrous dysplasia with involvement of craniofacial bones, mandible, ribs and extremities. A 18-year-old man showed remarkable right facial swelling who had been treated on right femur 3 years ago with a bone graft for pathologic fracture and he recognized facial swelling 5 years ago. Extraoral radiograms and computed tomogram showed diffuse sclerosis with a ground glass appearance of the most cranial bones, facial bones. The right mandibular lesion showed very expansile lesion with mottled appearance. Bone scans showed mutifocal increased uptakes in craniofacial bones, right mandible, bilaterally in ribs, humerus, femur, tibia and characteristic varus deformity of right femur (shepherd's crook defomity). This case showed exceptionally bilateral, extensive nature of bone lesion and didn't show any features of skin pigmentation and endocrine disturbances.

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MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions

  • Seok, Heeyoung;Ham, Juyoung;Jang, Eun-Sook;Chi, Sung Wook
    • Molecules and Cells
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    • v.39 no.5
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    • pp.375-381
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    • 2016
  • MicroRNAs (miRNAs) are small non-coding RNAs (~22 nucleotides) regulating gene expression at the post-transcriptional level. By directing the RNA-induced silencing complex (RISC) to bind specific target mRNAs, miRNA can repress target genes and affect various biological phenotypes. Functional miRNA target recognition is known to majorly attribute specificity to consecutive pairing with seed region (position 2-8) of miRNA. Recent advances in a transcriptome-wide method of mapping miRNA binding sites (Ago HITS-CLIP) elucidated that a large portion of miRNA-target interactions in vivo are mediated not only through the canonical "seed sites" but also via non-canonical sites (~15-80%), setting the stage to expand and determine their properties. Here we focus on recent findings from transcriptome-wide non-canonical miRNA-target interactions, specifically regarding "nucleation bulges" and "seed-like motifs". We also discuss insights from Ago HITS-CLIP data alongside structural and biochemical studies, which highlight putative mechanisms of miRNA target recognition, and the biological significance of these non-canonical sites mediating marginal repression.

Vital Tooth Bleaching: The State of Art (생활치아 미백술)

  • Choi, Dong Hun
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.7 no.1
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    • pp.6-17
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    • 1998
  • Tooth bleaching was being done more than 100 years ago, but the standard for vital tooth bleaching for the last quarter century has been the use of hydrogen peroxide with heat or with a combination of heat and light. The major disadvantages of this process are high cost, unpredictability of results, and patient discomfort. In March, 1989, the dental world was introduced to a new vital tooth bleaching process by Haywood and Heymann in their article "Nightguard vital bleaching(NGVB)." Interestingly enough, this simple technique could have been developed years ago if we had known about the chemical effects of carbamide peroxide on tooth structure. NGVB has created a resurgence in the area of bleaching, primarily because of its relative ease of application, the safety of the materials used, low cost, and the high percentage of successful treatments. This article was to explain simply about all around NGVB(etiology of stains, bleaching chemicals and mechanisms, bleaching effectiveness, side effect, documentation, indications, treatment therapy, laboratory procedure, case reports)

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Some Schemes for the sustainable Development of Korean Laver Industry (우리나라 김 산업 발전을 위한 논점과 방안)

  • Ock, Young-Soo
    • The Journal of Fisheries Business Administration
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    • v.41 no.2
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    • pp.25-44
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    • 2010
  • The laver has been cultivated long time ago in Korea. And traditional production system was changed to new system about 30 years ago. The new production system is understood the specialization of laver products, that is, originally individual fishery households made final laver products from raw cultured laver in sea working to dry working in land, but the new system was separated raw laver production in sea and dry laver production, which made final dry laver products by purchase the raw laver in land. This change has been increased laver production, 10 billion sheets in 2000's from 5 billion sheets in 1980's. And rapid production increase gave rise to some troubles on laver industry that is a serious drop in real laver prices, discord structure between raw laver producer and dry laver producer, stagnation of laver consumption, etc. Now Korea is the best laver production country together with Japan in world. Then we have to consider some schemes for the sustainable development of laver industry. One of such schemes is export enlargement of laver against world. The consumption of laver has been globally increased in recent. The other is the grading test problem of dry laver. Because the rapid increase of laver production caused to drop laver quality. Then we seriously have to consider the grading test of dry laver for high level quality production.

Solitary Skull Metastasis as the Initial Sign of Follicular Thyroid Cancer - A Case Report - (갑상선 여포암의 초기 증상으로서의 단발성 두개골 전이 1예)

  • Choi, Su-Yun;Cha, Jin-Woo;Song, Sun-Chun;Jang, Hea-Kim;Soh, Euy-Yong
    • Korean Journal of Head & Neck Oncology
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    • v.23 no.1
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    • pp.41-45
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    • 2007
  • A 60 years old female patient presented with $8{\times}6\;cm$ sized painless oval mass in the left parietal region. She had left lobectomy of thyroid gland 10 years ago. Cranial CT, MRI, FGD PET-CT showed a solid mass which invaded left parietal bone. After embolization, craniectomy with tumor excision was performed. Histological examination revealed metastatic follicular cancer originated thyroid gland, with vascular and dura invasion. Postoperatively, neck CT showed right thyroid multiple nodules and right level III multiple lymph node enlargement. Thyroid function test was normal, but level of thyroglobulin was high (72ng/ml). So she had right lobectomy of thyroid gland with lymph node dissection under a diagnosis of follicular carcinoma. But histological examination revealed adenomatous hyperplasia and not lymph node metastasis. After operation, she received radioiodine therapy of 150mCi and then the level of thyroglobulin normalized (8.4ng/ml). The patient is under follow-up since she had operation 4 months ago.

Analysis of a Dynamic PLS of the Biped Walking RGO-Robot for a Trainning of Rehabilitation (척수마비 재활훈련용 이족보행 RGO 로봇의 Dynam ic PLS 생체역학적 특성분석 <응력해석과 FEM을 중심으로>)

  • 김명회;장대진;박창일;박영필
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2002.05a
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    • pp.136-141
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    • 2002
  • This paper presents a design and a control of a biped walking RGO-robot and dynamic walking simulation for this system. The biped walking RGO-robot is distinguished from other one by which has a very light-weight and a new AGO type with servo motors. The gait of a biped walking RGO-robot depends on the constrains of mechanical kinematics and initial posture. The stability of dynamic walking is investigated by ZMP(Zero Moment Point) of the biped walking RGO-robot. It is designed according to a human wear type and is able to accomodate itself to human environments. The joints of each leg are adopted with a good kinematic characteristics. To test of the analysis of joint kinematic properties, we did the strain stress analysis of dynamic PLS and the study of FEM with a dynamic PLS. It will be expect that the spinal cord injury patients are able to train effectively with a biped walking AGO-robot.

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Ventricular Septal Defect Associated with Aortic Insufficiency (대동맥판막 폐쇄부전이 동반된 심실중격결손증의 외과적 치료)

  • 두홍서
    • Journal of Chest Surgery
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    • v.21 no.6
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    • pp.1111-1116
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    • 1988
  • Neurofibromatosis is very rare syndrome characterized by abnormal cutaneous pigmentation and numerous skin tumors was described by Smith in 1849, which is inherited as an autosomal dominant trait. Von Recklinghausen reported 2 cases of multiple skin and subcutaneous tumors in 1982. Malignant peripheral nerve tumors, although generally rare, are one of the most characteristic malignant tumors associated with Neurofibromatosis. We have experienced 3 cases of malignant Schwannoma in neurofibroma patients from 1982 to 1988 for 6 years at Thoracic and Cardiovascular surgery department, College of Medicine, Yonsei University, Seoul, Korea. l. One is 62 years old female who was taken total hysterectomy followed by irradiation treatment due to Uterine Carcinoma 21 years ago. She had a large bulging mass on left anterior chest wall and was taken enbloc resection of tumor including rib confirmed malignant Schwannoma. 2. Another is 18 years old female who had large bulging mass on right chest wall and pleural effusion in right thoracic cavity. Thoracentesis revealed a large amount of lymphocytes misdiagnosed of Tbc, pleurisy with Neurofibromatosis. We performed tissue biopsy on bulging mass and the specimen was confirmed malignant Schwannoma 2 months after first diagnosis of Tbc. pleurisy. She was not accessible to radical resection because of far advanced malignant Schwannoma at that time. 3. Third case is 28 years old male who was taken enbloc resection of tumor including rib due to Neurofibroma with Neurofibromatosis at M. hospital 6 months ago. But he had rapid growing mass at operation site again and taken tissue biopsy confirmed of malignant Schwannoma. He was not accessible to enbloc resection due to malignant Schwannoma extending to mediastinal structures.

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