• 전자공학회논문지B
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• 제33B권12호
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• pp.45-61
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• 1996

This paper presents the ECG data compression using wavelet transform (WT) and adaptive fractal interpolation (AFI). The WT has the subband coding scheme. The fractal compression method represents any range of ECG signal by fractal interpolation parameters. Specially, the AFI used the adaptive range sizes and got good performance for ECG data cmpression. In this algorithm, the AFI is applied into the low frequency part of WT. The MIT/BIH arhythmia data was used for evaluation. The compression rate using WT and AFI algorithm is better than the compression rate using AFI. The WT and AFI algorithm yields compression ratio as high as 21.0 wihtout any entropy coding.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.221-224
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• 1996

This paper presents the ECG data compression using wavelet transform(WT) and adaptive fractal interpolation(AFI). The WT has the subband coding scheme. The fractal compression method represents any range of ECG signal by fractal interpolation parameters. Specially, the AFI used the adaptive range sizes and got good performance for ECG data compression. In this algorithm, the AFI is applied into the low frequency part of WT. The MIT/BIH arrhythmia data was used for evaluation. The compression rate using WT and AFI algorithm is better than the compression rate using AFI. The WT and AFI algorithm yields compression ratio as high as 21.0 without any entroy coding.

• Korean Journal of Acupuncture
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• 제27권2호
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• pp.13-24
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• 2010

Objectives : Ulcerative colitis is a chronic relapsing inflammatory disease in the gastrointestinal tract. We investigated whether Aurantii fructus immaturus (AFI) pharmacopuncture has antioxidative and anti-inflammatory effects. Methods : in vitro experiments, 1,1-diphenyl-2-picryl hydrazyl (DPPH) free radical scavenging activity, superoxide dismutase (SOD) activity, prevention on $H_2O_2$-induced cell death in RAW264.7 cell line, DNA fragmentation, and cyclooxygenase-2 mRNA expression induced by lipopolysaccharide (LPS), were analyzed to investigate antioxidative and anti-inflammatory effect of AFI pharmacopuncture. in vivo experiment, a murine model of dextran sulfate sodium (DSS)-induced colitis was used to examine the effect of AFI pharmacopuncture on CV12 at different doses of 5 ${\mu}l$, 0.5 ${\mu}l$, 0.05 ${\mu}l$ for 10 days. Body weight, colon length and macroscopic features were investigated. Results : AFI pharmacopuncture showed DPPH free radical scavenging and SOD active effects in a dose-dependent manner. AFI pharmacopuncture showed a protective effect against $H_2O_2$-induced cell injury and also attenuated LPS-induced COX-2 mRNA expression. In a DSS- induced colitis murine model, however, AFI pharmacopuncture at CV12 had no anti-inflammatory effects. Conclusions : The present results suggest that AFI pharmacopuncture extract may have anti- inflammatory and antioxidative effects in vivo test, but further research on the underlying mechanism is required.

• Molecules and Cells
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• 제46권11호
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• pp.655-663
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• 2023

Autophagy dysfunction is associated with human diseases and conditions including neurodegenerative diseases, metabolic issues, and chronic infections. Additionally, the decline in autophagic activity contributes to tissue and organ dysfunction and aging-related diseases. Several factors, such as down-regulation of autophagy components and activators, oxidative damage, microinflammation, and impaired autophagy flux, are linked to autophagy decline. An autophagy flux impairment (AFI) has been implicated in neurological disorders and in certain other pathological conditions. Here, to enhance our understanding of AFI, we conducted a comprehensive literature review of findings derived from two well-studied cellular stress models: glucose deprivation and replicative senescence. Glucose deprivation is a condition in which cells heavily rely on oxidative phosphorylation for ATP generation. Autophagy is activated, but its flux is hindered at the autolysis step, primarily due to an impairment of lysosomal acidity. Cells undergoing replicative senescence also experience AFI, which is also known to be caused by lysosomal acidity failure. Both glucose deprivation and replicative senescence elevate levels of reactive oxygen species (ROS), affecting lysosomal acidification. Mitochondrial alterations play a crucial role in elevating ROS generation and reducing lysosomal acidity, highlighting their association with autophagy dysfunction and disease conditions. This paper delves into the underlying molecular and cellular pathways of AFI in glucose-deprived cells, providing insights into potential strategies for managing AFI that is driven by lysosomal acidity failure. Furthermore, the investigation on the roles of mitochondrial dysfunction sheds light on the potential effectiveness of modulating mitochondrial function to overcome AFI, offering new possibilities for therapeutic interventions.

• Journal of Gastric Cancer
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• 제16권3호
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• pp.152-160
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• 2016

Purpose: Endoscopic diagnosis of gastric cancer (GC) that emerges after eradication of Helicobacter pylori may be affected by unique morphological changes. Using comprehensive endoscopic imaging, which can reveal biological alterations in gastric mucosa after eradication, previous studies demonstrated that Congo red chromoendoscopy (CRE) might clearly show an acid non-secretory area (ANA) with malignant potential, while autofluorescence imaging (AFI) without drug injection or dyeing may achieve early detection or prediction of GC. We aimed to determine whether AFI might be an alternative to CRE for identification of high-risk areas of gastric carcinogenesis after eradication. Materials and Methods: We included 27 sequential patients with metachronous GC detected during endoscopic surveillance for a mean of 82.8 months after curative endoscopic resection for primary GC and eradication. After their H. pylori infection status was evaluated by clinical interviews and $^{13}C$-urea breath tests, the consistency in the extension of corpus atrophy (e.g., open-type or closed-type atrophy) between AFI and CRE was investigated as a primary endpoint. Results: Inconsistencies in atrophic extension between AFI and CRE were observed in 6 of 27 patients, although CRE revealed all GC cases in the ANA. Interobserver and intraobserver agreements in the evaluation of atrophic extension by AFI were significantly less than those for CRE. Conclusions: We demonstrated that AFI findings might be less reliable for the evaluation of gastric mucosa with malignant potential after eradication than CRE findings. Therefore, special attention should be paid when we clinically evaluate AFI findings of background gastric mucosa after eradication (University Hospital Medical Information Network Center registration number: UMIN000020849).

• 한국환경복원기술학회지
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• 제4권4호
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• pp.25-35
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• 2001

This study aims to find out the growth characteristics of riparian plants on the artificial floating islands (AFI). Three types of experiments were performed. The vegetation growth were compared by the plant-supporting materials; natural cotton mat, coir mat on the AFI or in the water, and natural soil at the waterfront. Major findings are; 1. The survival rate of riparian plants was 100% on both coir-mat and cotton-matislands, which implies that we may substitute cheaper cotton for expensive coir-mat. 2. Both natural cotton mat and coir mat were good for the growth of plants. Especially, the natural cotton mat was good for Sparganium stoloniferum and Miscanthus sacchariflorus, and the coir mat was good for Typha latifolia. 3. The growth rate of stem and root showed difference between the stem-removed plants and stem-remaining plants. As a whole, the growth rate of stem-removed plants was bigger than the one of stem-remaining plants. 4. The growth rate of plants showed difference between those grown on the AFI and those grown in the water. The growth rate of plant on the AFI was bigger than the one in the water. 5. The growth rate of plants on the AFI was bigger than the one on the natural soil at the waterfront.

• 생태와환경
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• 제41권spc호
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• pp.93-98
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• 2008

인공식물섬의 BOD, SS, T-N, T-P제거효율과 조류의 성장억제 능력을 분석하였으며 조류제어효과에 있어서 미생물보유활성화, 식물의 흡수효과에 대한 각각의 효과성을 판단하기 위해 구성요소별 장치를 구성하여 실험하였다. 구성요소별 장치는 (1) Blank Test, (2) 인공식물섬(VAFI) $0.25m^2$, (3) 식물을 식재 하지 않은 인공식물섬(AFI) $0.25m^2$, (4) 인공식물섬을 수면위로 부유시키기 위한 부력재 $0.25m^2$, (5) Media (부력재 $0.25m^2$에 50cm 길이로 Media를 4줄 부착)이다. BOD제거는 VAFI, AFI, 부력재, Media에서 각각 82.7, 80.8, 45.2, 59.6%로 나타났다. T-N제거는 VAFI, AFI, Media에서 각각 51.2, 31.7, 25.1%로 나타났다. T-P제거는 VAFI, AFI, 부력재, Media에서 각각 23.3, 16.7, 10.0, 13.3%로 나타났다. 엽록소-${alpha}$는 VAFI에서 97.9%가 제거되었다. VAFI의 구성 요소별 제거율은 차광효과 35.1%,미생물의 복합작용에 의한 효과 61%, 식물과 뿌리에 의한 효과 1.8%인 것으로 나타났다.

• 대한산업공학회지
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• 제8권2호
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• pp.23-31
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• 1982

A method of selecting parameters of Dodge-type continuous camping plans is proposed ; a sampling plan is designed so that its AFI curve passes through two designated points. AOQL contour lines are also drawn which can be used as a reference in choosing these points.

• 호스피스
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• 통권42호
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• pp.4-5
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• 2008

• 대한의용생체공학회:의공학회지
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• 제17권1호
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• pp.121-128
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• 1996

본 논문은 심전도 데이터 압축을 위해 적응 프랙탈 보간(AFI)알고리듬 방법을 제안한다. 기존의 분할 프랙탈 보간(PFI) 알고리듬은 고정된 크기의 정의역 블럭을 사용한다. 따라서 그 재생오차가 원래의 심전도 신호의 특정 부분에 집중된다. 이 문제를 해결하기 위해 적응 프랙탈 보간 알고리듬에서는 가변 정의역 블럭을 사용한다. 만약 미리 정한 허용오차가 만족되지 않으면 정의역 블럭은 두개의 더 작은 정의역 블럭들로 나뉘어지게 된다. 큰 정의역 블럭들은 높은 압축 효율을 얻기 위해 굴곡이 적은 파형을 부호화 하는데 사용되고, 더 작은 정의역 블럭들은 신호의 질을 유지하기 위해 급격히 변화하는 파형을 부호화 하는데 사용된다. 제안된 알고리즘은 MIT/BIH 데이터베이스를 사용하여 평가되었다. AFI알고리듬은 주어진 압축률에서 기존의 PFI알고리듬보다 상대적으로 적은 재생 오차를 나타냈다. 약 7.13% 정도의 실효치 차이가 허용되는 응용에서, AFI알고리듬은 매개변수들에 대한 엔트로피 코딩 없이 10.51 이상의 압축률을 얻을 수 있었다.