• Steel and Composite Structures
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• 제33권3호
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• pp.403-432
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• 2019

Axially functionally graded (AFG) beams are a new class of composite structures that have continuous variations in material and/or geometrical parameters along the axial direction. In this study, the exact analytical solutions for the free vibration of AFG and uniform beams with general elastic supports are obtained by using Euler-Bernoulli beam theory. The elastic supports are modeled with linear rotational and lateral translational springs. Moreover, the material and/or geometrical properties of the AFG beams are assumed to vary continuously and together along the length of the beam according to the power-law forms. Accordingly, the accuracy, efficiency and capability of the proposed formulations are demonstrated by comparing the responses of the numerical examples with the available solutions. In the following, the effects of the elastic end restraints and AFG parameters, namely, gradient index and gradient coefficient, on the values of the first three natural frequencies of the AFG and uniform beams are investigated comprehensively. The analytical solutions are presented in tabular and graphical forms and can be used as the benchmark solutions. Furthermore, the results presented herein can be utilized for design of inhomogeneous beams with various supporting conditions.

• Advances in nano research
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• 제16권3호
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• pp.265-272
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• 2024

In this paper, the problem of static bending of axially functionally graded (AFG) nanobeam is formulated with the local stress(Lσ)- and strain-driven(εD) two-phase local/nonlocal integral models (TPNIMs). The novelty of the present study aims to compare the size-effects of nonlocal integral models on bending deflections of AFG Euler-Bernoulli nano-beams. The integral relation between strain and nonlocal stress components based on two types nonlocal integral models is transformed unitedly and equivalently into differential form with constitutive boundary conditions. Purely LσD- and εD-NIMs would lead to ill-posed mathematical formulation, and Purely εD- and LσD-nonlocal differential models (NDM) may result in inconsistent size-dependent bending responses. The general differential quadrature method is applied to obtain the numerical results for bending deflection and moment of AFG nanobeam subjected to different boundary and loading conditions. The influence of AFG index, nonlocal models, and nonlocal parameters on the bending deflections of AFG Euler-Bernoulli nanobeams is investigated numerically. A consistent softening effects can be obtained for both LσD- and εD-TPNIMs. The results from current work may provide useful guidelines for designing and optimizing AFG Euler-Bernoulli beam based nano instruments.

• Toxicological Research
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• 제21권4호
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• pp.339-345
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• 2005

Aflatoxins are produced by Aspergillus flavus, parasiticus that grows in improperly stored cereals. Aflatoxin $B_1\;(AFB_1)$ is a potent hepatocarcinogen in a variety of experimental animals including human beings. In spite of a high attention to the hepatocarcinogenecity of aflatoxins, the relative toxicity of other types $(AFB_2,\;AFG_1\;and\;AFG_2)$ of the toxins is not fully clarified. Sprague-Dawley male rats were orally administered with $AFB_1,\;AFB_2,\;AFG_1\;and\;AFG_2$ at the dose of 250, 1250, and $2500\;{\mu}g/kg$ body weight. Animals were then killed at 12, 24 or 48 hrs following aflatoxin adminstration. Subsequently the relative weight of liver was measured and histopathological examination on the liver was performed. Level of 8-OxodG and expression of ras gene in the liver was determined. The relative liver weights at high doses of $AFB_1\;and\;AFG_1$ was significantly low. The treatment of $AFB_1$ at the high dose of $2500\;{\mu}g/kg$ showed vacuolar degeneration and centrilobular hepatic necrosis with inflammatory cells. The pathological changes by $AFB_2\;AFG_1,\;and\;AFG_2$ were not clearly found. The formation of 8-OxodG by $AFB_1$ increased in a dose-dependent manner up to 24 hrs after a single treatment of $AFB_1$ thereafter decreased to the level of the control. The treatments of $AFB_2\;AFG_1,\;and\;AFG_2$ showed an inconsistent pattern in the formation of 8-OxodG in the liver of rats with increasing time. The expression of ras oncogene in the liver by $AFB_1$ at the dose of $1250\;{\mu}g/kg$ was increased twice compared to the control. The treatments of $AFB_2\;AFG_1,\;and\;AFG_2$ at all doses decreased the expression of ras in the liver. These results in the present study indicate that $AFB_1$ among aflatoxins with low comparable levels is the most toxic as determined by early biomarkers such as 8-OxodG formation and ras expression. However, the levels of 8-OxodG and ras as biomarkers were not useful to predict the relative hepatocarcinogenicity of aflatoxins to $AFB_1$ in the present model. Further studies are required to look for other biomarkers to predict carcinogenic potency of aflatoxins.

• Food Science and Biotechnology
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• 제18권6호
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• pp.1505-1510
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• 2009

Arginyl-fructose (AF) and arginyl-fructosyl-glucose (AFG) were chemically synthesized and purified. Their in vitro and cellular antioxidant activity was investigated using oxygen radical absorbance capacity (ORAC) and cellular antioxidant activity assay, respectively. The peroxyl radical scavenging activity of AF was much higher than that of AFG, which was in good agreement with their reduction capacity to donate electrons or hydrogen atoms. On the other hand, the hydroxyl radical scavenging activity of AF was weaker than that of AFG, which was consistent with their metal chelating activity, suggesting that AFG-$Cu^{2+}$ complex may be less redox-active than AF-$Cu^{2+}$ complex due to 1 glucose molecule attached. The cellular antioxidant activity of AF and AFG appeared to depend on both their permeability into cell membrane and the scavenging activity on peroxyl or hydroxyl radicals. These results indicate that AF and AFG, Maillard reaction products, may have a high potential as a material for the development of nutraceutical food with antioxidant activity.

• Mycobiology
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• 제42권4호
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• pp.339-345
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• 2014

During 2011~2013, a total of 729 samples for 19 types of medicinal plant were collected from Seoulyekryungsi in Seoul, Korea, and investigated for the presence of aflatoxins. The samples were analyzed using immunoaffinity column cleanup and high-performance liquid chromatography coupled to a fluorescence detector after post-column derivatization. Aflatoxins were found in 124 out of the 729 analyzed samples: 65 containing aflatoxin B1 (AFB1), 24 with aflatoxin B2 (AFB2), 15 with aflatoxin G1 (AFG1), and 20 samples with aflatoxin G2 (AFG2). The ranges for positive samples were $0.1{\sim}404.7{\mu}g/kg$ for AFB1, $0.1{\sim}10.0{\mu}g/kg$ for AFB2, $0.1{\sim}635.3{\mu}g/kg$ for AFG1, $0.1{\sim}182.5{\mu}g/kg$ for AFG2, and $0.1{\sim}1,043.9{\mu}g/kg$ for total aflatoxins. Most of the medicinal plant samples (721, 98.9%) were below legal limits, but 8 samples exceeded the legal limits of 10 and $15{\mu}g/kg$ established by the Korean standard for AFB1 and total aflatoxins (the sum of AFB1, AFB2, AFG1 and AFG2), respectively.

• Steel and Composite Structures
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• 제28권6호
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• pp.749-758
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• 2018

Free axial vibration of axially functionally graded (AFG) nanorods is studied by focusing on the inertia of lateral motions and shear stiffness effects. To this end, Bishop's theory considering the inertia of the lateral motions and shear stiffness effects and the nonlocal theory considering the small scale effect are used. The material properties are assumed to change continuously through the length of the AFG nanorod according to a power-law distribution. Then, nonlocal governing equation of motion and boundary conditions are derived by implementing the Hamilton's principle. The governing equation is solved using the harmonic differential quadrature method (HDQM), After that, the first five axial natural frequencies of the AFG nanorod with clamped-clamped end condition are obtained. In the next step, effects of various parameters like the length of the AFG nanorod, the diameter of the AFG nanorod, material properties, and the nonlocal parameter value on natural frequencies are investigated. Results of the present study can be useful in more accurate design of nano-electro-mechanical systems in which nanotubes are used.

• Steel and Composite Structures
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• 제52권5호
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• pp.557-569
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• 2024

Nonlinear internal modals interactions analysis of axially functionally graded nanorods is evaluated on the basis of nonlocal elasticity theory and Rayleigh beam model for the first time. Functionally graded materials can be determined as nonhomogeneous composites which are obtained by combining of two various materials in order to get a new ideal material. In this research, material properties of nanorods are supposed to be calmly varied along the axial direction. Hamilton's principle is used to derive the equations with consideration of Von-Kármán's geometrically nonlinearity. Harmonic Differential Quadrature (HDQ) and Multiple Scale (MS) solution techniques are used to derive an approximate-analytic solution to the linear and nonlinear free axial vibration problem of non-classical nanorods for clamped-clamped and clamped-free boundary conditions. A parametric study is carried out to indicate the effects of index of AFG, aspect ratio, mode number, internal resonances and nonlinear amplitude on nonlinear nonlocal frequencies of axially functionally graded nanorods. Also, the effects of nonlocal and nonlinear coefficients and AFG index on relationships of internal resonances have been investigated. The presented theatrical-semi analytical model has the ability to predict very suitable results for extracting the internal modal interactions in the AFG nanorod.

• 천문학회지
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• 제29권spc1호
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• pp.127-128
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• 1996

The solar neighbourhood is the starting point for studies of the structure and evolution of the Galactic disk. Yet, our knowledge of the relative frequencies, distances, ages, chemical abundances, velocities, and birthplaces of the nearby stars is severely incomplete. We have determined complete, homogeneous, and precise such data for a kinematically unbiased sample of $\~$12,000 local F and G dwarf stars and describe a first, significant result from it.

• 한국조명전기설비학회:학술대회논문집
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• 한국조명전기설비학회 2004년도 학술대회 논문집
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• pp.97-100
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• 2004

This paper introduced an artificial fault generator which was operated in the Go-Chang field-test center and explained the result of single line-to-ground fault by AFG. The AFG can basically experiment line-to-line and line-to-ground faults. This facility directly connected distribution transmission lines, so the test results are very useful for power system analysis and protection. Using the function of the AFG, we briefly said the test methods ud results for the 22.9[kV-v] and $6.6[kV-{\Delta}]$ system.

• Structural Engineering and Mechanics
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• 제61권5호
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• pp.685-691
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• 2017

The free transverse vibrations of axially functionally graded (AFG) cantilever beams with concentrated masses attached at different points are studied in this paper. The material properties of the AFG beam, consisting of metal and ceramic, vary continuously in the axial direction according to an established law form. Approximated solutions for the title problem are obtained by means of the Ritz Method. The influence of the material variation on the natural frequencies of vibration of the functionally graded beam is investigated and compared with the influence of the variation of the cross section. The phenomenon of dynamic stiffening of beams can be observed in various situations. The accuracy of the procedure is verified through results available in the literature that can be represented by the model under study.