• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.723-726
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• 2013

Background: Breast cancer is worldwide the most common cancer in women and is a major public health problem. Genes with high or low penetrance are now clearly implicated in the onset of breast cancer, mostly the BRCA genes. All women in families at high risk of breast cancer do not develop tumours, even when they carry the familial mutation, suggesting the existence of genetic and environmental protective factors. Several studies have shown that consanguinity is linked to a decreased or an increased risk of breast cancer, but to the best of our knowledge, there is no study concerning the association between consanguinity and the occurrence of tumours in women with high risk of breast cancer. The objective of this study was to examine whether parental consanguinity in families with genetic predisposition to breast cancer affect the risk of siblings for having this cancer. Materials and Methods: Over a six-year period, 72 different patients with a histological diagnosis of breast or ovarian cancer from 42 families were recruited for genetic counselling to the Department of Medical Genetics, Rabat. Consanguinity rate was determined in cases and compared to the consanguinity rate in the Moroccan general population. Results: Consanguinity rates were 9.72% in patients and 15.3% in controls, but the difference was statistically not significant (p>0.001) and the mean coefficient of consanguinity was lower in breast cancer patients (0.0034) than in controls (0.0065). Conclusions: Despite the relatively small sample size of the current study, our results suggest that parental consanguinity in Moroccan women might not be associated with an altered risk of breast cancer. Large scale studies should be carried out to confirm our results and to develop public health programs.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.713-716
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• 2013

Social and behavioral scientists have proposed that a person's belief system crucially influences his or her behaviour, and therefore may affect outcomes of pain management. The purpose of this study was to explore the relationship between analgesic beliefs, analgesic adherence and pain experience amongst Taiwanese cancer outpatients. The cross-sectional study included 92 oncology outpatients in two teaching hospitals in the Taipei area of Taiwan. The research instruments included the Pain Opioid Analgesic Beliefs Scale-Cancer (POABS-CA), opioid adherence, and the Brief Pain Inventory-Chinese (BPI-Chinese). Beliefs about pain and opioids demonstrated a significant relationship with patients' opioid adherence (r = -0.30, p < 0.01). The more negative beliefs regarding opioids and pain the patient had, the worse their adherence to around the clock (ATC) analgesic regimen. However, there was no significant correlation between opioid belief and pain experience. As well, there were no significant relationships between adherence to opioid regimen and any of the measures of pain experience. The study highlights the potential importance of a patient's pain and opioid beliefs in adherence to pain medication.

• Journal of Oral Medicine and Pain
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• 제40권2호
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• pp.47-54
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• 2015

Purpose: Besides depression and anxiety, recently pain catastrophizing has been emphasized for an important psychological factor explaining pain response in various pain conditions including temporomandibular disorders (TMDs). The aims of this study were to evaluate pain catastrophizing of TMD patients and to investigate how the level of pain catastrophizing related with clinical variables and psychometric morbidity. Methods: Inclusion criterion was all new TMD patients ${\geq}18$ years old attending the Department of Orofacial Pain and Oral Medicine of Dankook University Dental Hospital (Cheonan, Korea) over three-month period in 2014, who completed questionnaires. The questionnaires included the Brief Pain Inventory (BPI), Pain Catastrophizing Scale (PCS), and Symptom Check List- 90-Revised (SCL-90-R). All of them were examined clinically and diagnosed. Results: One hundred fifty five patients diagnosed as TMDs were participated in this study (mean age of $38.7{\pm}15.2$ years, male:female=1:2.5). Mean PCS score of the patients was 17.3 with standard deviation of 12.6. By the median of the PCS score (i.e., 15), the subjects were categorized into the high (${\geq}15$) and low catastrophizers (<15). Increased pain severity and interference and increased score of psychological features of SCL-90-R were found in the TMD patients with higher level of catastrophizing (p<0.001) and there was weak to moderate correlation between those factors (p<0.05). Difference in catastrophizing level was not found for other variables such as age, gender, duration of pain, education level and types of TMDs. Conclusions: Conclusively, pain catastrophizing of TMD patients relates positively to pain severity and pain interference. In addition to depression and anxiety, pain catastrophizing is positively correlated with variable other psychological morbidity such as somatization, obsessive- compulsive, interpersonal sensitivity, paranoid ideation and psychoticism. Types of TMD diagnosis do not seem to affect catastrophizing level. The results of this study suggest that pain catastrophizing should be emphasized and assessed in the TMD patients.

• Journal of Oral Medicine and Pain
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• 제42권4호
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• pp.116-124
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• 2017

Purpose: Burning mouth syndrome (BMS) is a disabling pain that mostly occurs in elderly women, but rarely in men. It is characterized by an unremitting oral burning sensation and pain without detectable oral mucosal changes. We investigated the clinical and hematologic features of middle-aged men with BMS, and compared the results to those of men with oral mucositis. Methods: Five men with BMS ($48.60{\pm}6.19years$) and five age-matched controls with oral mucositis ($49.80{\pm}15.26years$) underwent clinical and psychological evaluations and blood tests. Psychological status was evaluated using the Symptom Checklist-90-Revised. Cortisol, estradiol, progesterone, testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), adrenocorticotropic hormone (ACTH), and antidiuretic hormone (ADH) levels and erythrocyte sedimentation rate (ESR) were determined from the blood samples. Results: ADH level was significantly lower in men with BMS than in the controls. ADH levels correlated with testosterone (p<0.01), and ACTH levels strongly correlated with ESR (p<0.05). Progesterone level positively correlated with FSH and LH levels. Pain intensity on a visual analogue scale correlated with estradiol level only in men with BMS. Among psychological factors, the obsessive-compulsive disorder, interpersonal-sensitivity, and anxiety scores were higher in men with BMS than in the controls (p<0.05). However, no correlations were observed between the psychological and hematologic factors in both groups. The BMS symptoms presented only on the tongue, with the lateral border being the most prevalent area. Conclusions: Men with BMS may experience dysregulated endocrinologic or psychoneuroendocrinologic interactions, which might affect oral BMS symptoms, aggravating the severity of the burning sensation.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2008년도 추계종합학술대회 B
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• pp.261-264
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• 2008

IPv6 has been proposed and deployed to cater the shortage of IPv4 addresses. It is expected to foresee mobile phones, pocket PCs, home devices and any other kind of network capable devices to be connected to the Internet with the introduction and deployment of IPv6. This scenario will bring in more challenges to the existing network infrastructure especially in the network security area. Firewalls are the simplest and the most basic form of protection to ensure network security. Nowadays, firewalls' usage has been extended from not only to protect the whole network but also appear as software firewalls to protect each network devices. IPv6 and IPv4 are not interoperable as there are separate networking stacks for each protocol. Therefore, the existing states of the art in firewalling need to be reengineered. In our context here, we pay attention only to the IPv6 firewalls configuration anomalies without considering other factors. Pre-evaluation of security risk is important in any organization especially a large scale network deployment where an add on rules to the firewall may affect the up and running network. We proposed a new probabilistic based model to evaluate the security risks based on examining the existing firewall rules. Hence, the network administrators can pre-evaluate the possible risk incurred in their current network security implementation in the IPv6 network. The outcome from our proposed pre-evaluation model will be the possibilities in percentage that the IPv6 firewall is configured wrongly or insecurely where known attacks such as DoS attack, Probation attack, Renumbering attack and etc can be launched easily. Besides that, we suggest and recommend few important rules set that should be included in configuring IPv6 firewall rules.

• 벤처창업연구
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• 제10권5호
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• pp.219-231
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• 2015

오픈 이노베이션은 기업의 기술혁신활동에 큰 영향을 미치는 것으로 알려져 있다. 한편 벤처기업의 경우 상대적으로 기업 규모가 작아 활용 가능한 내부자원에 한계가 있어 개방형 혁신을 통해 외부와의 협력을 확대하는 활동은 매우 중요하다. 따라서 본 연구는 벤처기업의 기술혁신 성과에 영향을 미치는 기업가정신, 혁신역량, 외부협력의 관계를 규명하여 기술혁신 성과를 극대화하는 방안을 모색하고자 한다. 이를 위해 부산 지역의 벤처기업을 대상으로 기술혁신활동 성과에 영향을 미치는 기업가정신, 혁신역량 및 외부협력의 관계를 분석했다. 기업가정신은 혁신역량, 외부협력, 기술혁신성과에 긍정적 영향을 미치고, 혁신역량은 외부협력과 기술혁신성과에 긍정적인 영향을 미치며, 외부협력 또한 기술혁신성과에 긍정적 영향을 미치는 것으로 나타났다. 그리고 혁신역량, 외부협력은 각각 기업가정신과 기술혁신성과간의 관계에 긍정적 매개역할을 하는 것으로 나타났다. 혁신역량과 외부협력은 함께 기업가정신과 기술혁신성과간의 관계에 긍정적 매개역할을 한다는 결론을 도출하였다.

• 한국조경학회지
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• 제27권1호
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• pp.79-89
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• 1999

Recent expansion of urban parks has been partly successful in terms of providing urban outdoor recreation space. Unfortunately we paid very little attention to the importance of providing regional identity to urban parks until recently. Thus one of the most important tasks of the contemporary landscape architects of Korea is to investigate ways to improve regional identity of urban parks. This study is aimed at evaluating how well the current urban parks have realized their own regional identity. To test the effectiveness of the concept of 'identity', the identity items were created, while a research model was developed by using such variables as in urban park identity, park satisfaction, belongingness to the region, and residential satisfaction. In order to test the model, the causations were analyzed. Meanwhile, the scales to evaluating identity were reviewed by means of the unstructures group interview, and were finally determined as 10 items; culture, uniqueness, symbolic, historic nature, homogeneity, harmony, difference, public benefit, nativeness and traditionality. Data from three new towns in the capital region-Bundang, Ilsan and Sanbon-were collected, and their central parks were referred to a questionnaire survey. The data were processed using descriptive statistics, correlation analysis, multiple regression analysis and path analysis. It was found through this survey that subjects 'sentiments regarding the sample towns' regional identity differed slightly. Residents of Bundang felt the strongest amount of regional identity, followed by those of Ilsan and Sanbon. In addition, the most important scale on regional identity is 'park satisfaction', followed by 'belongingness to the region' and 'residental satisfaction'. The path analysis was conducted to interpret the causations in a more detailed and comprehensive way than correlation analysis. As a result, it was proven that the regional identity affects 'belingingness to region' through the intermediated variable 'park satisfaction', while affecting ' residential satisfaction' through the intermediate variables 'park satisfaction' and 'beligningness to region'. In other words, although the regional identity of a park does not directly affect 'belongingness to region' or 'residental satisfaction', it has indirect effects on them through intermediate variables.

• 한국정보과학회논문지:시스템및이론
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• 제37권3호
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• pp.127-137
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• 2010

다양한 과학 분야에서 대규모의 계산집중적인 어플리케이션들이 많은 그리드 자원을 활용해감에 따라 그 실행 관리와 제어의 어려움도 증가하였다. 어플리케이션의 반복되는 실행으로 축적된 작업 이력을 참조하여 어플리케이션의 특성을 파악하고 그리드 자원 선택 정책을 결정하였다. 본 논문은 그리드 컴퓨팅 환경과 이를 활용한 어플리케이션의 이력을 분석하기 위해 통계적 기법인 PBDF(Plackett-Burman with Fold-Over)계획법을 적용하였다. PBDF는 그리드 환경과 어플리케이션에서 주요한 요인들을 파악하고, 그것들이 얼마만큼 영향을 미치는 가를 수치화한다. 영향력 큰 요인은 작업 이력에서 참조 프로파일을 찾고 적절한 자원을 선택하는데 사용하였다. 응용의 수행 결과를 다시 작업 이력에 포함시키고 인자의 신뢰도를 조정하였다. 본 연구는 항공우주 연구 그리드의 작업 이력을 분석하여 적응형 자원 선택 알고리즘을 제안하였다. 주요한 요인들의 영향력을 계산하고 자원 선택 정책에 반영하는 실험을 하였다. 또한, 수행이 끝난 후 인자의 신뢰도를 평가해 그리드 환경 변화에 적응하는 알고리즘의 유효성을 검증하였다. 오류가 빈번한 그리드 환경에서 자원 선택 기법을 평가하기 위해 다양한 시나리오에서 그 적응력을 실험하였다.

• The Journal of Korean Physical Therapy
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• 제21권4호
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• pp.37-42
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• 2009

Purpose: The purpose of this study was to determine the effect of physical performance on bone mineral density (BMD) in elderly women. Methods: Twenty-one elderly women participated in this study. After testing functional ambulation category (FAC), they were classified into two groups: dependent walking group, those who could not walk independently (FAC 0~2, n=11) and independent walking group those who could walk independently (FAC 3~5, n=10). Outcome measures were: general characteristics, physical performance and BMD. General characteristics included age, body mass index (BMI) and waist-hip ratio. Physical performance included the chair rise test (CRT) and the modified fall efficacy scale (MFES). BMD was represented in the osteoporosis index (OI), T-score and Z-score. BMD was evaluated in calcaneal bone, using OsteoPro. The data was analyzed using SPSS 12.0 software and the Mann-Whitney U test and the Spearman correlation. Results: Age, BMI and waist hip ratio, which all affect BMD, showed no significant differences between groups (p>0.05). But the FAC 3~5 group showed a significantly higher score for CRT, MFES and T-score, compared with the FAC 0~2 group (p<0.05). The T-score was correlated with CRT and MFES scores (p<0.05). Conclusion: There is a positive relationship between physical performance and BMD. Therefore, improved physical performance can have a beneficial effect by reducing osteoporosis in elderly women, considering a positive relationship between physical performance and BMD.

• 한국도로학회논문집
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• 제2권1호
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• pp.147-156
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• 2000

다짐은 포장 공용성에 중요한 영향을 미친다고 알려져 있다. 따라서 이 다짐공정을 포장의 소성변형과 근본적으로 동일하다고 가정하여, 다짐밀도를 롤러다짐수의 항으로 표현하는 이론 모델링식을 정립하였다. 정립된 식의 우수한 데이터 예측능력은 유도과정에 세운 가정들의 검증과 더불어 이 식의 사용 정당화에 대해 확신시켜준다. 유도된 식에 의하면, 대수 밀도 차를 대수 다짐회수의 항으로 그림을 그리면 일차함수의 직선관계식이 주어진다. 그러나 이 직선관계는 공기온도에 의한 냉각과 진동롤러의 진폭과 주기 등의 효과가 존재하면 더 이상 성립되지 않음이 판명된다. 본 연구에서는 이러한 세 요인들에 대한 영향도 함께 연구하여 더 전반적이고 성공가능성을 보여주는 새로운 다짐밀도 식을 제안하였다. 이 제안식을 응용하여 특정다짐공정에 요하는 전체 롤러다짐회수와 최종다짐밀도를 구하는 관계식을 다짐 연구 중 최초로 제시하였다.