• Journal of The Korean Association For Science Education
• /
• v.24 no.2
• /
• pp.226-233
• /
• 2004

The purpose of this study was to test whether the degrees of desyncronization in cranial nerves were related to correlation coefficient between brain waves measured on scalp. Based on the hypothesis. this research intended to describe the patterns of brain wave during scientific reasoning. EEG (electroencephalography) signals in 19 electrodes were recorded from elementary (6th grade) and middle (7th, 8th grade) school students as they performed roller-ball tasks: planning experiment, cognitive conflict, bridging, metacognition, and at rest (eyes closed and eyes opened). The results showed that the smaller the correlation coefficient was, the bigger the degrees of desyncronization. As compared to resting periods, the correlation coefficients in prefrontal and frontal lobe decreased during scientific reasoning. And the nerves in prefrontal and frontal lobes were most active during scientific reasoning. These results suggest that the correlation coefficient in addition to frequency of brain waves be analysed to get meaningful results of researches on scientific reasoning by brain wave.

• Korean Journal of Materials Research
• /
• v.26 no.4
• /
• pp.187-193
• /
• 2016

Fabrication of iron oxide/carbon nanotube composite structures for detection of ammonia gas at room temperature is reported. The iron oxide/carbon nanotube composite structures are fabricated by in situ co-arc-discharge method using a graphite source with varying numbers of iron wires inserted. The composite structures reveal higher response signals at room temperature than at high temperatures. As the number of iron wires inserted increased, the volume of carbon nanotubes and iron nanoparticles produced increased. The oxidation condition of the composite structures varied the carbon nanotube/iron oxide ratio in the structure and, consequently, the resistance of the structures and, finally, the ammonia gas sensing performance. The highest sensor performance was realized with $500^{\circ}C/2h$ oxidation heat-treatment condition, in which most of the carbon nanotubes were removed from the composite and iron oxide played the main role of ammonia sensing. The response signal level was 62% at room temperature. We also found that UV irradiation enhances the sensing response with reduced recovery time.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.13 no.8
• /
• pp.1491-1496
• /
• 2009

This paper presents an digital based input/output interface circuit for controlling and monitoring the Diesel Engine Generator for emergency. In order to monitor and control of the Emergency Diesel Engine Generator, controlling and monitoring circuits need 5 analog input channels, 2 pick-up coil measuring circuits, 10 digital input channels containing Broken Wire Detect function, and 7 relay control signal output channels. This system performs signal processing of input signal taking advantage of simple filter circuit, photo-coupler and comparator circuit at analog input parts, and output signals for main relay is designed acting by double control, so it prevents malfunction completely. And it improves accuracy of speed input signal by applying digital circuit that processes rick-up coil signal.

• Journal of the Korean Society for Nondestructive Testing
• /
• v.35 no.3
• /
• pp.179-184
• /
• 2015

In this study, the flap fatigue test of a 48 m long wind turbine blade was performed for 1 million cycles to evaluate the characteristics of acoustic emission signals generated from fatigue damage of the wind blades. As the number of hits and total energy continued to increase during the first 0.6 million cycles, blade damage was constant. The rise-time result showed that the major aspects of damage were initiation and propagation of matrix cracks. In addition, the signal analysis of each channel showed that the most seriously damaged sections were the joint between the skin and spar, 20 m from the connection, and the spot of actual damage was observable by visual inspection. It turned out that the event source location was related to the change in each channel's total energy. It is expected that these findings will be useful for the optimal design of wind turbine blades.

• The Korean Journal of Physiology and Pharmacology
• /
• v.8 no.4
• /
• pp.181-185
• /
• 2004

Extracellular regulated protein kinase1/2 (pERK1/2) is one of the major regulatory factors for transcription of the c-fos oncogene in neurons. The purpose of this study was to evaluate the expression of phosphorylated ERK1/2 within the vestibular nuclei (VN) of rats following acute arterial hypotension. Following the acute arterial hypotension induced by rapid hemorrhage, a significant number of pERK1/2-immunoreactive neurons appeared bilaterally in the caudal aspect of the medial and inferior VN. No labeling of pERK1/2 was observed in the lateral VN. The peak expression of pERK1/2 in these nuclei occurred within 5 min after hemorrhage. However, in bilaterally labyrinthectomized rats, the appearance of pERK1/2-immunoreactive neurons was eliminated in the VN. Western blot confirmed the effect of bilateral labyrinthectomy on pERK1/2 protein expression in the medial vestibular nucleus 5 min after hemorrhage. These results suggest that, following acute hypotension, afferent signals from the peripheral vestibular receptors are required for activation of ERK 1/2 in the VN.

• Journal of Ecology and Environment
• /
• v.30 no.1
• /
• pp.101-105
• /
• 2007

Lammas growth, a rare phenomenon for Korean red pine (Pinus densiflora), occurred in 2006. Lammas shoots showed higher frequency and longer length in Seoul's hotter urban center than in urban boundary or suburban forest sites. Frequency and length showed a close correlation with urbanization density and vegetation cover expressed in NDVI. Air temperature in the late summer of 2006 was more than $1^{\circ}C$ higher than an average year. Of the predominant environmental signals that modulate bud flush, only temperature changed significantly during the year. Differences in temperature between the urban centers, urban boundaries and suburban forests correlated with varying land-use density. The rise in temperature likely spurred lammas growth of the Korean red pine. Symptoms of climate change are being detected throughout the world, and its consequences will be clearer in the future. Considerate interest in the responses of ecological systems to the variable changes is required to prepare for unforeseeable crises. Monitoring of diverse ecological phenomena at Long Term Ecological Research sites could offer harbingers of change.

• Journal of Food Hygiene and Safety
• /
• v.26 no.4
• /
• pp.302-307
• /
• 2011

One of the most important objectives of post-marketing monitoring of dietary supplements is the early detection of unknown and unexpected adverse events (AEs). Several causality algorithms, such as the Naranjo scale, the RUCAM scale, and the M & V scale are available for the estimation of the likelihood of causation between a product and an AE. Based on the existing algorithms, the Korea Food & Drug Administration has developed a new algorithm tool to reflect the characteristics of dietary supplements in the causality analysis. However, additional work will be required to confirm if the newly developed algorithm tool has reasonable sensitivity and not to generate an unacceptable number of false positives signals.

• Molecules and Cells
• /
• v.28 no.1
• /
• pp.25-30
• /
• 2009

${\beta}$-Arrestins turn off G protein-mediated signals and initiate distinct G protein-independent signaling pathways. We previously demonstrated that angiotensin $AT_1$ receptorbound ${\beta}$-arrestin 1 is cleaved after $Phe^{388}$ upon angiotensin II stimulation. The mechanism and signaling pathway of angiotensin II-induced ${\beta}$-arrestin cleavage remain largely unknown. Here, we show that protein Tyr phosphatase activity is involved in the regulation of ${\beta}$-arrestin 1 cleavage. Tagging of green fluorescent protein (GFP) either to the N-terminus or C-terminus of ${\beta}$-arrestin 1 induced conformational changes and the cleavage of ${\beta}$-arrestin 1 without angiotensin $AT_1$ receptor activation. Orthovanadate and molybdate, inhibitors of protein Tyr phosphatase, attenuated the cleavage of C-terminal GFP-tagged ${\beta}$-arrestin 1 in vitro. The inhibitory effects of okadaic acid and pyrophosphate, which are inhibitors of protein Ser/Thr phosphatase, were less than those of protein Tyr phosphatase inhibitors. Cell-permeable pervanadate inhibited angiotensin II-induced cleavage of ${\beta}$-arrestin 1 in COS-1 cells. Our findings suggest that Tyr phosphorylation signaling is involved in the regulation of angiotensin II-induced ${\beta}$-arrestin cleavage.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.22 no.4
• /
• pp.121-125
• /
• 2018

This paper presents the assessment of 7-wire strand monitoring using acoustic emission technique for bridges. 7-wire strand is widely used construction materials to provide additional tensile force to bridges. PSC (PreStressed Concrete) bridge and cable-stayed bridge are representatives for such cases. However, as the bridge aging progresses recently, corrosion problems of strand are emerging. For this reason, various NDT (Non-Destructive Test) methods for cable inspection are being studied and applied to the field. One of the NDT methods, acoustic emission technique, is known as an effective technique to detect cable damage and breakage. In this study, to evaluate the applicability of acoustic emission technique to bridges, acoustic emission signals according to damage of the strand were acquired and analyzed by tensile test. Moreover, The optimal AE sensor type was selected for field application. As a result, it is considered that the acoustic emission technique will be able to detect corrosion breakage and signs of rupture.

• The Korean Journal of Physiology and Pharmacology
• /
• v.3 no.1
• /
• pp.19-27
• /
• 1999

Apoptosis has been implicated in the pathophysiological mechanisms of various neurodegenerative diseases. In a variety of cell types, oxidative stress has been demonstrated to play an important role in the apoptotic cell death. However, the exact mechanism of oxidative stress-induced apoptosis in neuronal cells is not known. In this study, we induced oxidative stress in IMR-32 human neuroblastoma cells with tert- butylhydroperoxide (TBHP), which was confirmed by significantly reduced glutathione content and glutathione reductase activity, and increased glutathione peroxidase activity. TBHP induced decrease in cell viability and increase in DNA fragmentation, a hallmark of apoptosis, in a dose-dependent manner. TBHP also induced a sustained increase in intracellular $Ca^{2+}$ concentration, which was completely prevented either by EGTA, an extracellular $Ca^{2+}$ chelator or by flufenamic acid (FA), a non-selective cation channel (NSCC) blocker. These results indicate that the TBHP-induced intracellular $Ca^{2+}$ increase may be due to $Ca^{2+}$ influx through the activation of NSCCs. In addition, treatment with either an intracellular $Ca^{2+}$ chelator (BAPTA/AM) or FA significantly suppressed the TBHP-induced apoptosis. Moreover, TBHP increased the expression of p53 gene but decreased c-myc gene expression. Taken together, these results suggest that the oxidative stress-induced apoptosis in neuronal cells may be mediated through the activation of intracellular $Ca^{2+}$ signals and altered expression of p53 and c-myc.