• Title/Summary/Keyword: AE techniques

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Adverse pregnancy outcomes with assisted reproductive technology in non-obese women with polycystic ovary syndrome: a case-control study

  • Han, Ae-Ra;Kim, Hye-Ok;Cha, Sun-Wha;Park, Chan-Woo;Kim, Jin-Yeong;Yang, Kwang-Moon;Song, In-Ok;Koong, Mi-Kyoung;Kan, Inn-Soo
    • Clinical and Experimental Reproductive Medicine
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    • v.38 no.2
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    • pp.103-108
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    • 2011
  • Objective: To investigate adverse pregnancy outcomes in non-obese women with polycystic ovary syndrome (PCOS) compared with obese-PCOS and control groups. Methods: Women with PCOS who underwent assisted reproductive technology (ART) from August, 2003 to December, 2007, were considered. A total of 336 women with PCOS were included in the study group and 1,003 infertile women who had tubal factor as an indication for ART were collected as controls. They were divided into four groups: a non-obese PCOS group, obese-PCOS group, non-obese tubal factor group, and obese tubal factor group, with obesity defined by a body mass index over 25 kg/$m^2$, and reviewed focusing on the basal characteristics, ART outcomes, and adverse pregnancy outcomes. Results: There was no difference among the groups' the clinical pregnancy rate or live birth rate. Regarding adverse pregnancy outcomes, the miscarriage rate, multiple pregnancy rate, and prevalence of preterm delivery and pregnancy induced hypertension were not different among the four groups. The incidence of small for gestational age infant was higher in the PCOS groups than the tubal factor groups ($p$ <0.02). On the other hand, the morbidity of gestational diabetes mellitus (GDM) was not high in the non-obese PCOS group but was in the obese groups. And in the obese PCOS group, the newborns were heavier than in the other groups ($p$ <0.02). Conclusion: Non-obese PCOS presents many differences compared with obese PCOS, not only in the IVF-parameters but also in the morbidity of adverse pregnancy outcomes, especially in GDM and fetal macrosomia.

Modulation of G-CSF Secretion by Mutations of Non Alpha-Helical Region in N-Terminus (G-CSF 단백질 N-말단의 비 알파-Helix 영역의 돌연변이에 의한 분비 조절)

  • Park, Jeong-Hae;Park, Jung-Ae;Kang, Seok-Woo;Goo, Tae-Won;Chung, Kyung-Tae
    • Journal of Life Science
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    • v.21 no.12
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    • pp.1778-1783
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    • 2011
  • Hematopoietic cytokines regulate production of blood cells by stimulating proliferation and differentiation of bone marrow cells. Among these hematopoietic cytokines, called hematopoitic growth factors, glranulocyte-colony stimulating Factor (G-CSF), which regulates growth of neutrophils, is one of important therapeutic factors because cancer patients suffer with neutropenia which is severe reduction of neutrophils after chemotherapy. Two groups of recombinant G-CSF have approved and used for therapeutic purposes and many researches are still on-going to produce recombinant G-CSF by different techniques. We engineered human G-CSF with Bombyx specific endoplasmic reticulum (ER) signal sequence, therefore, secretion of human G-CSF protein was improved in Bombyx mori-origined cell line, Bm5. The Bombyx ER signal sequence and human G-CSF matured protein region chimera was further remodeled at the N-terminus of matured G-CSF protein to understand roles of N-terminus on outer cellular secretion and/or production. Three different mutants were generated deleting three amino acids in non alpha-helical region in N-terminus in order to scan important amino acids for G-CSF secretion. One of 3 different N-terminal deletion mutants showed dramatically reduction of secreted amount of G-CSF indicating its important role on secretion. The data suggest that remodeling in non alpha-helical region of N-terminus is also important for recombinant G-CSF production.

Characteristics of Speckle Errors of SeaWiFS Chlorophyll-α Concentration in the East Sea (동해 SeaWiFS 클로로필-α 농도의 스펙클 오차 특성)

  • Chae, Hwa-Jeong;Park, Kyung-Ae
    • Journal of the Korean earth science society
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    • v.30 no.2
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    • pp.234-246
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    • 2009
  • Characteristics of speckle errors of Sea-viewing Wide Field-of-view Sensor (SeaWiFS) chlorophyll-${\alpha}$ concentration were analyzed, and its causes were investigated by using SeaWiFS data in the East Sea from September 1997 to December 2007. The speckles with anomalously high concentrations were randomly distributed and showed remarkably high bias of greater than $10mg/m^3$, compared with their neighboring pixels. The speckles tended to appear frequently in winter, which might be related to cloud distribution. Ten-year averaged cloudiness of winter was much higher over the southeastern part, with frequent speckles, than the northwestern part of the East Sea. Statistical analysis results showed that the number of the speckles was increased as cloudiness increased. Normalized water-leaving radiance of the speckle pixel was considerably low at the short wavelengths (443, 490, and 510 nm), whereas the radiance at 555 nm band was normal. These low measurements produced extraordinarily high concentration from the chlorophyll-${\alpha}$ estimation formula. This study presented the speckle errors of SeaWiFS chlorophyll-${\alpha}$ concentration in the East Sea and suggested that more reliable chlorophyll-${\alpha}$ data based on appropriate ocean color remote sensing techniques should be used for the oceanic application researches.

SOURCE-FREQUENCY PHASE-REFERENCING OBSERVATION OF AGNS WITH KAVA USING SIMULTANEOUS DUAL-FREQUENCY RECEIVING

  • Zhao, Guang-Yao;Jung, Taehyun;Sohn, Bong Won;Kino, Motoki;Honma, Mareki;Dodson, Richard;Rioja, Maria;Han, Seog-Tae;Shibata, Katsunori;Byun, Do-Young;Akiyama, Kazunori;Algaba, Juan-Carlos;An, Tao;Cheng, Xiaopeng;Cho, Ilje;Cui, Yuzhu;Hada, Kazuhiro;Hodgson, Jeffrey A.;Jiang, Wu;Lee, Jee Won;Lee, Jeong Ae;Niinuma, Kotaro;Park, Jong-Ho;Ro, Hyunwook;Sawada-Satoh, Satoko;Shen, Zhi-Qiang;Tazaki, Fumie;Trippe, Sascha;Wajima, Kiyoaki;Zhang, Yingkang
    • Journal of The Korean Astronomical Society
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    • v.52 no.1
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    • pp.23-30
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    • 2019
  • The KVN(Korean VLBI Network)-style simultaneous multi-frequency receiving mode is demonstrated to be promising for mm-VLBI observations. Recently, other Very long baseline interferometry (VLBI) facilities all over the globe start to implement compatible optics systems. Simultaneous dual/multi-frequency VLBI observations at mm wavelengths with international baselines are thus possible. In this paper, we present the results from the first successful simultaneous 22/43 GHz dual-frequency observation with KaVA(KVN and VERA array), including images and astrometric results. Our analysis shows that the newly implemented simultaneous receiving system has brought a significant extension of the coherence time of the 43 GHz visibility phases along the international baselines. The astrometric results obtained with KaVA are consistent with those obtained with the independent analysis of the KVN data. Our results thus confirm the good performance of the simultaneous receiving systems for the nonKVN stations. Future simultaneous observations with more global stations bring even higher sensitivity and micro-arcsecond level astrometric measurements of the targets.

Study on the Textile Design using Buttons on Western clothing in the 18th·19th Centuries (18·19세기 서양 복식의 단추를 활용한 텍스타일 디자인 연구)

  • Lee, Eui-Jung;Kang, Kyung-Ae
    • Journal of the Korea Fashion and Costume Design Association
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    • v.24 no.2
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    • pp.97-115
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    • 2022
  • The study aims to explore a new direction for research on buttons by understanding the functions and artistic features of buttons on Western clothing in the 18th and 19th centuries, and to use the findings to develop a textile design. In terms of the research method, the period was set in the 18th and 19th centuries, when decorative features and artistic values of buttons on Western clothing reached theirpeak, while theoretical analysis was made based on literature and previous research papers on Western clothing, websites of the Metropolitan Museum and French Museum of Decorative Arts and other website materials, as well as special exhibition materials of the National Museum of Modern and Contemporary Art. Textile designs were developed using computer programs, including Clip Studio Paint and Adobe Photoshop, by integrating the reinterpreted motif of buttons in the 18th and 19th centuries and the styles that prevailed at that time. The results are as follows. First, buttons on Western clothing had the following three functions: a practical function, a symbolic function representing the wearer's status, and a decorative function expressing individuality and beauty. Second, buttons in the 18th century were works of art made with various handicraft techniques and were an important medium that expressed the wearer's fashion sense. In addition, buttons in the 19th century were mass-produced as a result of industrialization and took a major step forward with the development of materials and dyeing. Buttons reflected themes of poetry, drama, biblical stories, music and art, lifestyle,, along with the political and social atmosphere that rapidly changed after the revolution and fashion trends. Third, the artistic features and shapes of buttons were reinterpreted to create a design motif, and the design was developed reflecting the characteristic elements of the rococo style of the 18th century and the art nouveau style of the 19th century that can conform to modern fashion, thereby rediscovering the artistic meaning and value implied in buttons. In the future, the research on creative buttons of 20th century artists is expected to be conducted from various perspectives.

Recent Research Status of Postharvest Management of Broccoli (브로콜리 수확후 관리의 최근 연구 동향)

  • Choi, Ji-Weon;Lee, Woo-Moon;Kwak, Jung-Ho;Kim, Won-Bae;Kim, Ji-Gang;Lee, Seung-Ku;Cho, Mi-Ae
    • Journal of the Korean Society of International Agriculture
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    • v.23 no.5
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    • pp.497-502
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    • 2011
  • Broccoli is considered as one of the functional foods to offer a hearty supply of the nutrient-rich vegetable in the world. Broccoli contains high level of phytochemicals, and that is selected as one of the top 10 vegetables for human health promotion. Especially, glucosinolates and flavonoids are well known as anti free oxygen radicals in vegetables and fruits. In Korea, broccoli consumption has increased to well known on the health-beneficial vegetables since 2000. However, broccoli has many problems of postharvest management since the quality of harvested heads quickly declines. Major problems are the floret yellowing, wilting, off-odor, and decay. The multiple postharvest applications improve broccoli quality and cold treatment including pre-cooling extends on the shelf-life with circumstance of optimum storage which is 0℃ temperature and a range of 95-100% relative humidity. Controlled atmosphere or modified atmosphere packaging can be used as supplemental treatments to extend postharvest life. 1-2% O2 + 5-10% CO2 is currently recommended for broccoli. Postharvest management is important for broccoli because price fluctuations depend on harvest time and quality. In this study, we tried to review physiological change of broccoli after the harvest, storage method, and various techniques to optimize quality during distribution.

Actions to Expand the Use of Geospatial Data and Satellite Imagery for Improved Estimation of Carbon Sinks in the LULUCF Sector

  • Ji-Ae Jung;Yoonrang Cho;Sunmin Lee;Moung-Jin Lee
    • Korean Journal of Remote Sensing
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    • v.40 no.2
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    • pp.203-217
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    • 2024
  • The Land Use, Land-Use Change and Forestry (LULUCF) sector of the National Greenhouse Gas Inventory is crucial for obtaining data on carbon sinks, necessitating accurate estimations. This study analyzes cases of countries applying the LULUCF sector at the Tier 3 level to propose enhanced methodologies for carbon sink estimation. In nations like Japan and Western Europe, satellite spatial information such as SPOT, Landsat, and Light Detection and Ranging (LiDAR)is used alongside national statistical data to estimate LULUCF. However, in Korea, the lack of land use change data and the absence of integrated management by category, measurement is predominantly conducted at the Tier 1 level, except for certain forest areas. In this study, Space-borne LiDAR Global Ecosystem Dynamics Investigation (GEDI) was used to calculate forest canopy heights based on Relative Height 100 (RH100) in the cities of Icheon, Gwangju, and Yeoju in Gyeonggi Province, Korea. These canopy heights were compared with the 1:5,000 scale forest maps used for the National Inventory Report in Korea. The GEDI data showed a maximum canopy height of 29.44 meters (m) in Gwangju, contrasting with the forest type maps that reported heights up to 34 m in Gwangju and parts of Icheon, and a minimum of 2 m in Icheon. Additionally, this study utilized Ordinary Least Squares(OLS)regression analysis to compare GEDI RH100 data with forest stand heights at the eup-myeon-dong level using ArcGIS, revealing Standard Deviations (SDs)ranging from -1.4 to 2.5, indicating significant regional variability. Areas where forest stand heights were higher than GEDI measurements showed greater variability, whereas locations with lower tree heights from forest type maps demonstrated lower SDs. The discrepancies between GEDI and actual measurements suggest the potential for improving height estimations through the application of high-resolution remote sensing techniques. To enhance future assessments of forest biomass and carbon storage at the Tier 3 level, high-resolution, reliable data are essential. These findings underscore the urgent need for integrating high-resolution, spatially explicit LiDAR data to enhance the accuracy of carbon sink calculations in Korea.

A Novel Volumetric Method for Quantitation of Titanium Dioxide in Cosmetics (용량분석법을 이용한 화장품 중 티타늄옥사이드의 정량)

  • Kim, Young-So;Kim, Boo-Min;Park, Sang-Chul;Jeong, Hye-Jin;Chang, Ih-Seop
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.4 s.54
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    • pp.289-293
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    • 2005
  • Nowadays there are many sun protection cosmetics including organic or inorganic UV filter as an active ingredient. Chemically stable inorganic sunsEreen agents, usually metal oxides, we widely employed in high SPF products. Titanium dioxide is one of the most frequently used inorganic UV filters. It has been used as pigments for a long period of cosmetic history. With the development of micronization techniques, it becomes possible to incorporate titanium dioxide in sunscreen formulations without whitening effect and it becomes an important research topic. However, there are very few works related to quantitations of titanium dioxide in sunscreen products. In this research, we analyzed amounts of titanium dioxide in sunscreen cosmetics by adapting redof titration, reduction of Ti(IV) to Ti(III) and reoxidation to Ti(IV). After calcification of other organic ingredients of cosmetics, titanium dioxide is dissolved by hot sulfuric acid. The dissolved Ti(IV) is reduced to the Ti(III) by adding aluminum metals. The reduced Ti(III) is titrated against a standard oxidizing agent, Fe(III) (ammonium iron(III) sulfate), with potassium thiocyanate as an indicator In order to test accuracy and applicability of the proposed method, we analyzed the amounts of titanium dioxide in four types of sunscreen cosmetics, such as cream, make-up base, foundation and powder, after adding known amounts of titanium dioxide $(1{\sim}25w/w%)$. The percent recoveries of the titanium dioxide in four types of formulations were in the range between 96 and 105%. We also analyzed 7 commercial cosmetic products labeled titanium dioxide as an ingredient and compared the results with those of obtained from ICP-AES (Inductively Coupled Plasma-Atomic Emission Spectrometry), one of the most powerful atomic analysis techniques. The results showed that the titrated amounts were well coincided with the analyzed amounts of titanium dioxide by ICP-AES. Although instrumental analytical methods, ICP-MS (Inductively Coupled Plasma-Mass Spectrometry) and ICP-AES, are the best for the analysis of titanium, it is hard to adopt because of their high prices for small cosmetic companies. It was found that the volumetric method presented here gat e quantitative and reliable results with routine lab-wares and chemicals.

A Study of Anomaly Detection for ICT Infrastructure using Conditional Multimodal Autoencoder (ICT 인프라 이상탐지를 위한 조건부 멀티모달 오토인코더에 관한 연구)

  • Shin, Byungjin;Lee, Jonghoon;Han, Sangjin;Park, Choong-Shik
    • Journal of Intelligence and Information Systems
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    • v.27 no.3
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    • pp.57-73
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    • 2021
  • Maintenance and prevention of failure through anomaly detection of ICT infrastructure is becoming important. System monitoring data is multidimensional time series data. When we deal with multidimensional time series data, we have difficulty in considering both characteristics of multidimensional data and characteristics of time series data. When dealing with multidimensional data, correlation between variables should be considered. Existing methods such as probability and linear base, distance base, etc. are degraded due to limitations called the curse of dimensions. In addition, time series data is preprocessed by applying sliding window technique and time series decomposition for self-correlation analysis. These techniques are the cause of increasing the dimension of data, so it is necessary to supplement them. The anomaly detection field is an old research field, and statistical methods and regression analysis were used in the early days. Currently, there are active studies to apply machine learning and artificial neural network technology to this field. Statistically based methods are difficult to apply when data is non-homogeneous, and do not detect local outliers well. The regression analysis method compares the predictive value and the actual value after learning the regression formula based on the parametric statistics and it detects abnormality. Anomaly detection using regression analysis has the disadvantage that the performance is lowered when the model is not solid and the noise or outliers of the data are included. There is a restriction that learning data with noise or outliers should be used. The autoencoder using artificial neural networks is learned to output as similar as possible to input data. It has many advantages compared to existing probability and linear model, cluster analysis, and map learning. It can be applied to data that does not satisfy probability distribution or linear assumption. In addition, it is possible to learn non-mapping without label data for teaching. However, there is a limitation of local outlier identification of multidimensional data in anomaly detection, and there is a problem that the dimension of data is greatly increased due to the characteristics of time series data. In this study, we propose a CMAE (Conditional Multimodal Autoencoder) that enhances the performance of anomaly detection by considering local outliers and time series characteristics. First, we applied Multimodal Autoencoder (MAE) to improve the limitations of local outlier identification of multidimensional data. Multimodals are commonly used to learn different types of inputs, such as voice and image. The different modal shares the bottleneck effect of Autoencoder and it learns correlation. In addition, CAE (Conditional Autoencoder) was used to learn the characteristics of time series data effectively without increasing the dimension of data. In general, conditional input mainly uses category variables, but in this study, time was used as a condition to learn periodicity. The CMAE model proposed in this paper was verified by comparing with the Unimodal Autoencoder (UAE) and Multi-modal Autoencoder (MAE). The restoration performance of Autoencoder for 41 variables was confirmed in the proposed model and the comparison model. The restoration performance is different by variables, and the restoration is normally well operated because the loss value is small for Memory, Disk, and Network modals in all three Autoencoder models. The process modal did not show a significant difference in all three models, and the CPU modal showed excellent performance in CMAE. ROC curve was prepared for the evaluation of anomaly detection performance in the proposed model and the comparison model, and AUC, accuracy, precision, recall, and F1-score were compared. In all indicators, the performance was shown in the order of CMAE, MAE, and AE. Especially, the reproduction rate was 0.9828 for CMAE, which can be confirmed to detect almost most of the abnormalities. The accuracy of the model was also improved and 87.12%, and the F1-score was 0.8883, which is considered to be suitable for anomaly detection. In practical aspect, the proposed model has an additional advantage in addition to performance improvement. The use of techniques such as time series decomposition and sliding windows has the disadvantage of managing unnecessary procedures; and their dimensional increase can cause a decrease in the computational speed in inference.The proposed model has characteristics that are easy to apply to practical tasks such as inference speed and model management.

Estimation Analysis of the Value of Welfare Facilities for the Aged Management (노인복지시설의 경영가치 추정 분석)

  • Kim, Keum Hwan;Pak, Ae Kyung;Joe, Soon Joem
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.8 no.1
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    • pp.193-203
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    • 2013
  • The social welfare service is expanding to different field as the social welfare budget is increasing. By this opportunity, it needs to make clear of the basis of argument that the necessity of development of korean government's support and aid by social policy should be worked. Welfare economics perspective, this study used by the operating expenditure in welfare facilities for the elderly old people to effect social benefits to be gained, in other words, business value analysis. Local elderly people, provide opportunities to participate in the economic activities of the family welfare services offered to attainment of the elderly welfare policy, and provide disease prevention and health promotion opportunities, to enhance the satisfaction of life, including a wide range of impact will cause. In this study, elderly people use the welfare facilities for the elderly when they get the benefits by applying the AHP analysis techniques operating value was calculated. Elderly Welfare Center operated by the result of applying P senior welfare center Case of the metropolitan area value was estimated 248.4 billion won. Contribute to the effects caused by the cost factor of the analysis was 23.1% of the total 57.3 billion won. Independence elements 57.6 billion (23.2%), the analysis of the therapeutic elements 133.4 billion (53.7%) of the net was. The result of the study anticipates the role of basic research material for the necessity of intervention, support, and aid by the Welfare facilities for the elderly field at this point in time where the welfare budget policy in terms of universal social service is reinforced, rather than the trend, until recently, of realizing the Elderly welfare budget and service as Consumption expenditure and consumable benefits and the function of performing the effect and evaluation in tentative action of social conflict.

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