• Journal of Radiation Protection and Research
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• v.41 no.3
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• pp.206-210
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• 2016

Background: Ionizing radiation causes cellular damage and death through the direct damage and/or indirectly the production of ROS, which induces oxidative stress. This study was designed to evaluate the in vivo radioprotective effects of a bio-active material coated fabric (BMCF) against ${\gamma}$-irradiation-induced cellular damage in Sprague-Dawley (SD) rats. Materials and Methods: Healthy male SD rats wore bio-active material coated (concentrations in 10% and 30%) fabric for 7 days after 3 Gy of ${\gamma}$-irradiation. Radioprotective effects were evaluated by performing various biochemical assays including spleen and thymus index, WBC count, hepatic damage marker enzymes [aspartate transaminase (AST) and alanine transaminase (ALT)] in plasma, liver antioxidant enzymes, and mitochondrial activity in muscle. Results and Discussions: Exposure to ${\gamma}$-irradiation resulted in hepatocellular and immune systemic damage. Gamma-irradiation induced decreases in antioxidant enzymes. However, wearing the BMCF-30% decreased significantly AST and ALT activities in plasma. Furthermore, wearing the BMCF-30% increased SOD (superoxide dismutase) and mitochondrial activity. Conclusion: These results suggest that wearing BMCF offers effective radioprotection against ${\gamma}$-irradiation-induced cellular damage in SD rats.

• Korean Journal of Health Education and Promotion
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• v.26 no.4
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• pp.71-81
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• 2009

Objectives: This study furthers the currents understanding of alcohol use disorders, stress, mental health status and suicide among Seoul citizens. This study is to identify differences according to socio-demographic variables and variables which affect stress, mental status and suicide for developing mental health programs. Methods: The study subjects using cluster-stratified sampling method were 1234 adults over 19 years old from 17 dong, S-Ku in Seoul City. A cross-sectional study with face-to-face interview was used to collect data. A questionnaire measuring socio-demographic variables, Symptom Checklist-90-Revised (SCL-90-R) and psychosocial wellbeing index-short form (PWI-SF) was utilized. Results: Three findings in this study were discussed: (1) The prevalence of problem drinking and alcohol dependence and AUDIT score were significantly higher among male, younger age, and high level of education and income; (2) AUDIT score were related with stress, all 9 symptoms of SCL-R and suicide plan; (3) Problem drinkers were more likely to have 2.5 times of anxiety, 3.0 times of hostility, and 2.4 times psychoticism than non alcohol problem drinkers. Alcohol dependence drinkers were more likely to have 1.9 times of high risk group of stress, 4.1 times of obsessive-compulsive, 4.7 times of anxiety, 5.5 times of hostility, and 2.3 times psychoticism than non alcohol dependence drinkers. Conclusion: The findings suggest that the future intervention of Mental Health programs should be carefully designed and tailored by socio-demographic variables.

• Journal of the Korean Dietetic Association
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• v.22 no.4
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• pp.272-291
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• 2016

The purpose of this study was to investigate health-related habits, dietary habits, depression, stress, satisfaction of body weight, mini-dietary assessment (MDA) and dietary behaviors according to self-rated health among 255 university students in Kyungnam province. Statistical analyses were performed using the SPSS software package (version 19.0). The average ages of the subjects were 21.1 years. Participants were asked their self-rated health and 109, 105 and 41 students answered themselves as "healthy", "normal" and "unhealthy", respectively. The pocket money (P<0.05) was related with self-rated health, and meal frequency (P<0.01) of healthy group was higher than that of the unhealthy group. The self-reported depression level (P<0.01) and the score of depression (P<0.05) of the healthy group were lower than those of the unhealthy group. The self-reported stress level of the healthy group (P<0.05) was higher than that of the unhealthy group. The scores of nutritional behavior (P<0.05) and MDA (P<0.01) of the healthy group were higher than those of the unhealthy group. The scores for intakes of meat, fish, egg or beans, cereals and vegetables except kimchi, fruits, balanced diet and various foods were higher in the healthy group than in the unhealthy group. Our results suggest that pocket money, high meal frequency, low depression, satisfaction of present body weight, and good dietary behavior might influence good perception of self-rated health.

• Journal of the East Asian Society of Dietary Life
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• v.17 no.1
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• pp.1-10
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• 2007

The effects of mulberry-leaf powder Tofu(MPT) on anthropometric measurements, including bone mineral density(BMD) in the right carpus, biochemical bone turnover markers, serum levels of lipids and macrominerals, were investigated in 30 smoking male adults who lived in Choongnam were given MPT(100 g/day) for 4 weeks. The average ages, number of smoked cigarettes and packyear were 22.38 years, 15.12/day and 3.54 years, respectively. The nutrient contents per 100 g MPT were 86.10 kcal energy, 8.98 g protein, 0.53 mg fiber, 211.33 mg Ca and 1.59 g fat. Anthropometric measurements, including dietary intake using the 24-hours recall method, carpal BMD using DEXA, serum levels of protein, albumin and glucose, lipid profiles (cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) with Al(atherosclerosis index), HTR, CRF, LHBt, some biomarkers of BMD(serum alkaline phosphatase activity, osteocalcin, urinary DPD), and serum macrominerals(Ca, Ca/P ratio, Mg) and Pb were analyzed before and after consumption of MPT. After MPT consumption, dietary intakes of plant protein, total Ca and plant Ca increased significantly, but there were no significant differences in anthropometric measurements, BMD with bone metabolism markers, serum levels of protein, albumin or glucose, lipid profiles with AI, HTR, LHR and CRF.

• The Korean Journal of Community Living Science
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• v.16 no.2
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• pp.75-91
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• 2005

The purpose of this study was to examine the relationship between parenting stress, social support and the social development of preschool children in rural areas. The subject included 114 preschool children, along with their mothers, selected from kindergartens and day care centers in rural areas. The instruments included the parenting stress index, social support inventory and the social maturity scale. The statistics used from this data were t-test, one-way ANOYA(Scheffe test), correlation analysis and multiple regression analysis. This study showed that maternal parenting stress was influenced significantly by the related variables; gender of child, birth order of child, age of mother, educational attainment of mother, family income, religion, family type. And also, social support was influenced significantly by the above variables. The child's social development was influenced significantly by the variables that related child and the family. Correlation analysis indicated that parenting stress and social development of the child were relatively negative high correlation coefficients. And social support and social development of the child were relatively positive high correlation coefficients. The important factors on predicting social development of the child were found to be birth order of child, age of mother, educational attainment of mother, family income, religion, family type, daily stress, stress of difficult child, stress of parent-child dysfunctional interaction, educational distress, husband support, and other support. Especially stress of difficult child and husband support were important variables that predicted the social development of the preschool children.

• Phonetics and Speech Sciences
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• v.2 no.4
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• pp.185-192
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• 2010

The acoustic vowel space has been used as an acoustic parameter in dysarthric speech. The aim of this work was to examine mathematical formulae for acoustic vowel space and to apply these to Korean speakers with idiopathic Parkinson's disease(IPD). Five acoustic parameters were chosen from earlier works and one new parameter was proposed, the pentagonal vowel space. The six parameters included triangular vowel space (3 area), irregular quadrilateral vowel space (4 area), irregular pentagonal vowel space (5 area), vowel articulatory index (VAI), formant centralization ratio (FCR) and F2i/F1u ratio (F2 ratio). An experimental group of 32 IPD patients(male:female=16:16) and a control group of twenty healthy people (male:female=8:12) participated in the study and repeated vowels (/a-i-u-e-o/) three times. A correlation analysis was performed among the six parameters, 2-way ANOVA was done with gender and groups as independent factors, and an independent sample t-test was conducted between the male and the female group as post hoc comparison. All parameters were highly correlated with each other and only the FCR showed a high negative correlation with the others. The results of ANOVA showed a significant difference in F2 ratio, 3 area, 4 area and 5 area between gender and in 4 area and 5 area between groups. For the male members of the two groups, significant statistical differences were found in all parameters whereas no such differences were found for the female members. These findings indicated that the vowel space of the female group was wider than the vowel space of the male group. These differences may have been caused by gender-specific speech styles rather than by patho-physiological mechanisms. We also claim that the pentagonal vowel space is better than the other vowel spaces at representing the disordered speech in natural speech situations.

• Journal of the Korea Convergence Society
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• v.8 no.9
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• pp.49-57
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• 2017

The purpose of this study was to investigate factors affecting perceived oral health status according to socioeconomic status and community periodontal index(CPI) and decayed, missing, and filled teeth(DMFT) using the 6th Korean national health and nutritional examination survey(KNHANES VI) and provide a basic data for plan of policy. The higher the age, the lower the household income and education level, the worse the subjective oral health had better oral health and there was a tendency that the respondents who had no oral exam within 1 year and experienced CPI or DMFT estimated their own health as worse. It is needed to make policy development to resolve the inequality of oral health.

• Preventive Nutrition and Food Science
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• v.19 no.4
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• pp.333-342
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• 2014

Limited epidemiologic data is available regarding the cardiovascular effects of mercury exposure. The purpose of this study was to determine the relationship between mercury exposure from fish consumption and cardiovascular disease in a nationally representative sample of Korean adults using the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV 2008~2009). Survey logistic regression models accounting for the complex sampling were used to estimate the odds ratios (OR) adjusted for fish consumption frequency, age, education, individual annual income, household annual income, body mass index (BMI), waist circumference (WC), alcohol consumption status, and smoking status. The mean blood mercury level in the population was $5.44{\mu}g/L$. Trends toward increased blood mercury levels were seen for increased education level (P=0.0011), BMI (P<0.0001), WC (P<0.0001), and fish (i.e., anchovy) consumption frequency (P=0.0007). The unadjusted OR for hypertension in the highest blood mercury quartile was 1.450 [95% confidential interval (CI): 1.106~1.901] times higher than that of the lowest quartile. The fish consumption-adjusted OR for hypertension in the highest blood mercury quartile was 1.550 (95% CI: 1.131~2.123) times higher than that of the lowest quartile, and the OR for myocardial infarction or angina in the highest blood mercury quartile was 3.334 (95% CI: 1.338~8.308) times higher than that of the lowest quartile. No associations were observed between blood mercury levels and stroke. These findings suggest that mercury in the blood may be associated with an increased risk of hypertension and myocardial infarction or angina in the general Korean population.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1320-1331
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• 2009

Oxidative stress and inflammation are important events in the development of chronic inflammatory diseases including arthritis, atherosclerosis, diabetes, hypertension. Cynomorium songaricum (CS) has been used as a traditional Korean herbal medicine, and it is currently used in traditional clinics to treat frequent urination, spermatorrhea, weakness of the sinews and constipation in the folk medicine. The aim of this study was to determine whether fractionated extracts of CS inhibit free radical generation such as DPPH radical, superoxide radical, nitric oxide and peroxynitrite, production of nitrite an index of NO, $PGE_2$, iNOS, COX-2 and pro-inflammatory cytokines in lipopolysaccharide (LPS)-treated RAW 264.7 macrophages. Cytotoxic activity of extracts on RAW 264.7 cells was measured using 5-(3-caroboxymeth-oxyphenyl)-2H-tetra-zolium inner salt (MTS) assay. Our results indicated that the most superior extract which scavenged DPPH radical, reactive oxygen species (ROS) and RNS was CS ethyl acetate extract (CSEA). Moreover, CSEA significantly inhibited the LPS-induced NO, $PGE_2$ production and iNOS, COX-2 expression accompanied by an attenuation of TNF-$\alpha$, IL-$1{\beta}$ and IL-6 formation in macrophages. Furthermore, CSEA treatment also blocked LPS-induced intracellular ROS production and the activation of NF-${\kappa}B$. These findings indicate that CSEA inhibits the production of pro-inflammatory mediators and cytokines via the suppression of ROS production and NF-${\kappa}B$ activation. Take together, these results indicate that CSEA has the potential for use as an natural anti-oxidant and an agent of anti-chronic inflammatory diseases.

• Quality Improvement in Health Care
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• v.18 no.1
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• pp.15-26
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• 2012

Background : Many gastrectomy patients have experienced poor intake and it was cause of the decreasing nutritional status. The purpose of this study was to identify the amount of the intake food and the influencing factors among gastrectomy patients. Methods : A cross-sectional study was conducted with 163 patients who underwent gastrectomy. Data were collected through self-report questionnaires and chart review about demographic, clinical, nutritional status and dietary information and were analyzed with the SPSS 20.0 WIN program. Result : Among 163 patients, the group with over 3/4 intake food was 115(70.5%). The group with 1/2 intatke was 30(18.4%) and the group with the lowest intake of 1/4 was 18(11.1%). There were significant differences in single amount of intake food by patient's subjective feeling(P<.001). Single amount of intake food among three groups were no significant difference in type of gastrectomy, hospital length, body mass index and albumin level. Conclusion : The findings of the study showed that single amount of the intake food was correlated with subjective feeling of patients. Therefore, subjective feelings should be considered important factors in developing diet program for patients with gastrectomy.