• Title/Summary/Keyword: ADFP

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ADFP promoter polymorphism associated with marbling score in Korean cattle

  • Cheong, Hyun-Sub;Yoon, Du-Hak;Bae, Joon-Seol;Kim, Lyoung-Hyo;Kim, Eun-Mi;Kim, Ji-On;Hong, Jin;Kim, Nae-Soo;Shin, Hyoung-Doo
    • BMB Reports
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    • v.42 no.8
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    • pp.529-534
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    • 2009
  • Marbling score (MS) is the major trait that affects carcass quality in beef cattle. In this study, we investigated the association between genetic polymorphisms of the adipose differentiation-related protein gene (ADFP) and carcass traits in Korean cattle (also known as Hanwoo). Using direct DNA sequencing in 24 unrelated Korean cattle, 25 novel polymorphisms were identified within all exons and their flanking regions of ADFP, including the promoter region (1.5 kb). Among them, 21 polymorphic sites were selected for genotyping in the beef cattle (n = 425). Statistical analyses revealed that one promoter polymorphism (c.-56-18A > G) was associated with MS (P = 0.009). The 'A' allele of c.-56-18A > G exerted a lowering effect on MS, e.g., the lowest MS was found in 'A/A' (MS = 2.09 ${\pm}$ 1.23), intermediate in 'A/G' (MS = 2.11 ${\pm}$ 1.31), and the highest in 'G/G' (MS = 2.47 ${\pm}$ 1.47). Our findings suggest that these polymorphisms in ADFP might be important genetic factors involved in carcass quality in beef cattle.

Causality Analysis of Muscle Activation, Physical Strength and Daily Living Abilities Change among the Elderly due to a Health Promotion Exercise Program (건강운동에 의한 노인의 근활성, 체력 및 일상생활능력 변화의 인과관계)

  • Kim, Hee-Ra
    • The Journal of Korean Physical Therapy
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    • v.22 no.4
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    • pp.73-81
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    • 2010
  • Purpose: The purpose of this study was (1) to examine the effects of a Health Promotion Exercise Program (HPEP) on functional improvement, physical strength (PS) and muscle activation (MA), and the interactive influence with activities of daily living (ADL) and instrumental activities of daily living (IDAL) in the elderly, and (2) to develop and provide a HPEP for the elderly in order to prevent declines and impairments in integrated nerve function and physical capacity. Methods: Our study included relatively healthy elderly people aged 65 years or older. The experimental group, which was composed of 30 people, participated in a HPEP 50~60 minutes a day, 3 times a week, for a total of 12 weeks. Results: Confirmatory factor analysis (CFA) validated the measurement models for MA, physical strength, ADL and IADL with a p<0.01. This confirms (i) the beneficial effects of the ADFP on their MA and PS, and (ii) that their improvement in PS, in turn, can improve their IADL. The results of this study indicates that ADFP can help Korean seniors 65 years or older improve their MA, PS, ADL, and IADL, and do so synergistically. Conclusion: An HPEP, when organized in such a way that the elderly can easily do it, and when exercise items and intensity can be programmed and reorganized accordingly to individual physical and physiological characteristics by presenting 5 categorized health domains of physical strength, may be useful, especially because it can be practiced irrespective of time and place.

Development of An Agricultural Drought Evaluation Model for Administrative Decision Support (가뭄대책 행정지원을 위한 지역논가뭄평가모형 ADEM의 개발)

  • Jang, Min-Won;Chung, Ha-Woo;Park, Ki-Wook
    • Journal of Korean Society of Rural Planning
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    • v.9 no.2 s.19
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    • pp.29-37
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    • 2003
  • The objectives of this study are to develop an agricultural drought evaluation model based on administrative boundaries and to assist the effective drought-related decision-making of local governments. The model which was named ADEM(Administrative Drought Evaluation Model for Paddies) is designed to simulate daily water balance between available water quantities from various agricultural water facilities such as reservoirs, wells, pump stations, etc. and water requirements in paddies. And in order to numerically describe the agricultural drought severity, two indices were defined; One is ADFP(Agricultural Drought Frequency for Paddies) which is calculated with a frequency analysis of monthly water deficit, and the other is ADIP(Agricultural Drought Index for Paddies) with a scale of $-4.2{\sim}+4.2$. The developed model was applied to Yeoju district and showed good correspondence with the historical records of drought.