• Journal of Periodontal and Implant Science
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• v.45 no.4
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• pp.136-144
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• 2015

Purpose: The objective of this study was to comparatively assess the bone regenerative capacity of absorbable collagen sponge (ACS), biphasic calcium phosphate block (BCP) and collagenated biphasic calcium phosphate (CBCP) loaded with a low dose of recombinant human bone morphogenetic protein-2 (rhBMP-2). Methods: The CBCP was characterized by X-ray diffraction and scanning electron microscopy. In rabbit calvaria, four circular 8-mm-diameter defects were created and assigned to one of four groups: (1) blood-filled group (control), (2) rhBMP-2-soaked absorbable collagen sponge (0.05 mg/mL, 0.1 mL; CS group), (3) rhBMP-2-loaded BCP (BCP group), or (4) rhBMP-2-loaded CBCP (CBCP group). The animals were sacrificed either 2 weeks or 8 weeks postoperatively. Histological and histomorphometric analyses were performed. Results: The CBCP showed web-like collagen fibrils on and between particles. Greater dimensional stability was observed in the BCP and CBCP groups than in the control and the CS groups at 2 and 8 weeks. The new bone formation was significantly greater in the BCP and CBCP groups than in the control and CS groups at 2 weeks, but did not significantly differ among the four groups at 8 week. The CBCP group exhibited more new bone formation in the intergranular space and in the center of the defect compared to the BCP group at 2 weeks, but a similar histologic appearance was observed in both groups at 8 weeks. Conclusions: The dose of rhBMP-2 in the present study enhanced bone regeneration in the early healing period when loaded on BCP and CBCP in rabbit calvarial defects.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.14
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• pp.5749-5754
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• 2015

Cervical carcinoma is the main cause of cancer-related mortality in women and is correlated with more than 15 risk cofactors, including infection of cervical cells with high-risk types of HPV (hrHPV). Indeed, both aberrant methylation of the RASSF1A promoter and hrHPV infection are often observed in cervical carcinomas. The purpose of our meta-analysis was to evaluate the role of RASSF1A promoter methylation and hrHPV infection in cervical cancer. Our meta-analysis involved 895 cervical cancer patients and 454 control patients from 15 studies. Our results suggested that RASSF1A promoter hypermethylation increased the risk of cervical cancer (OR=9.77, 95%CI=[3.06, 31.26], P=0.0001, $I^2=78%$). By grouping cases according to cancer subtypes, we found that HPV infection was higher in cervical squamous cell carcinomas (SCCs) than in cervical adenocarcinomas/adenosquamous cancers (ACs/ASCs) (OR=4.00, 95%CI=[1.41, 11.30], P=0.009, $I^2=55%$). Interestingly, HPV infection tended to occur in cervical cancers with relatively low levels of RASSF1A promoter methylation (OR=0.59, 95%CI=[0.36, 0.99], P=0.05, I2=0%). Our study provides evidence of a possible interaction between HPV infection and RASSF1A promoter methylation in the development of cervical cancers.

• The Journal of the Korea Contents Association
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• v.5 no.5
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• pp.1-9
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• 2005

In this paper, we suggest multi colony interaction ant reinforcement learning model. This method is a hybrid of multi colony interaction by elite strategy and reinforcement teaming applying Temporal Difference(TD) learning to Ant-Q loaming. Proposed model is consisted of some independent AS colonies, and interaction achieves search according to elite strategy(Intensification, Diversification strategy) between the colonies. Intensification strategy enables to select of good path to use heuristic information of other agent colony. This makes to select the high frequency of the visit of a edge by agents through positive interaction of between the colonies. Diversification strategy makes to escape selection of the high frequency of the visit of a edge by agents achieve negative interaction by search information of other agent colony. Through this strategies, we could know that proposed reinforcement loaming method converges faster to optimal solution than original ACS and Ant-Q.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.2
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• pp.455-461
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• 2008

Enhanced Distributed Channel Access (EDCA) is a channel access scheme adopted by the IEEE 802.11e draft standard for QoS-enabled wireless local area networks. It classifies traffic into separate Access Categories (ACs) and achieves service differentiation by allowing each AC to have its own values of channel access parameters. This paper proposes a scheme to dynamically adapt the EDCA parameters to traffic environment so that they both maximize the throughput of non real-time traffics and meet the delay and throughput constraints of real-time traffics. For this purpose, we develop a design algorithm for efficient exploration of the EDCA parameter space. Using the algorithm, we derive a Pareto curve fur delay-throughput trade-off in each anticipated traffic environment. The Pareto database can then be used to optimally adjust the parameter according to the traffic environment and administrative policies. Simulation results show that compared with the default parameter configuration, the proposed scheme is better for delay, throughput guarantee and can improve the throughput of non real-time traffics by 12% on average.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.211-212
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• 2011

플라즈마를 제어하기 위해서는 플라즈마의 온도, 밀도, 에너지 분포등과 같은 플라즈마의 특성을 정확히 측정할 수 있어야한다. 핵융합발전에서는 플라즈마를 발생하기 위하여 플라즈마의 온도, 밀도 등 각종 변수들을 시공간적으로 계측, 분석할 수 있는 진달설비를 사용하고 있으며, 정확한 플라즈마 제어와 측정을 위한 새로운 진단기술을 개발하고 있다. 그리고 중요한 변수중에 하나인 플라즈마 이온온도를 측정하기 위해 중성입자 검출법이 잘 알려져 있다. 이 실험은 수소 중성입자가 토카막 내부의 플라즈마 이온과 충돌하면서 생성된 고속 중성입자의 에너지를 분석하는 실험이다. 본 연구의 실험방법은 수소 중성입자를 이온빔 장치에서 이온화 시킨 후 자체 제작한 가속기를 통하여 가속시켜 에너지 특성을 분석을 하는 것이다. 본 연구의 실험장치로 에너지 교정용 100 keV 이온빔 소스를 제작 하였고 이온빔 장치 내부에 수소기체를 주입하고 기체방전을 일으켜 플라즈마를 발생시켰다. 이온빔 외부에는 팬을 설치하고 전도성이 강한 물 대신 전도성이 약한 오일을 사용하여 냉각 하였다. 이온빔 장치와 결합될 이온 가속장치는 지름 300 mm, 두께 2 mm의 원형 구리판을 여러층으로 쌓아 전극으로 제작하였고 전극과 전극 사이에서 코로나 방전과 스파크를 방지하기 위해 전극 둘레에 코로나링을 설치 하였다. 또한 전극 사이마다 1G${\Omega}$의 저항을 설치한 후 고전압을 생성하여 이온 가속 효율을 증대시켰다. 진공시스템으로는 Alcatel사의 CFF100 터보분자 펌프와 우성진공사의 MVP24 진공로타리펌프를 결합하여 사용하였으며, 진공도측정은 Alcatel사의 ACS1000 장치를 사용하였다. 고진공후 고속 중성입자의 이온화와 에너지 측정을 위한 전하교환기를 설치하였다. 전하교환기로는 진공시스템을 별도로 설치하고 비용이 비교적 많이 드는 기체형 전하교환기 대신 소형화가 가능하고 유지보수가 좋은 고체형 전하교환기 제작하여 실험 하였다. 전하교환기에서 이온화된 고속 중성입자가 전기장이나 자장에 영향을 받았을때 에너지분포를 디텍터를 통해 측정하였다. 즉, 이온화된 중성입자의 에너지가 실리콘 다이오드를 통해 전압 펄스 신호로 변환되고 이차 증폭기를 통해 전압 펄스 신호들이 증폭한다. 에너지 측정을 위한 디텍터는 소형화가 가능하고 비용이 비교적 적게 드는 실리콘 다이오드를 설치하였다. 본 연구결과 중성입자 에너지 분석 장치가 실제 핵융합 장치의 플라즈마 이온온도와 특성 측정에 적용할 수 있으며, 앞으로 개발될 여러 형태의 응용 플라즈마 발생장치의 플라즈마 진단에 이용될 것으로 기대한다.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.54.2-54.2
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• 2011

We present a study of HII regions in M51 using HST/ACS images taken as part of the Hubble Heritage Program. We found about 19,600 HII regions in M51 with $H_{\alpha}$ luminosity in the range of $L=10^{35.5}-10^{39.0}\;erg\;s^{-1}$. The $H_{\alpha}$ luminosity function of HII regions (HII LF) in M51 is well represented by a double power law with its index ${\alpha}=-2.25{\pm}0.02$ for the bright part and ${\alpha}=-1.42{\pm}0.01$ for the faint part, separated at a break point $L=10^{37.1}\;erg\;s^{-1}$. Comparison with simulated HII LFs suggests that this break is caused by the transition of HII region ionizing sources, from low-mass clusters (including several OB stars) to more massive clusters (including several tens of OB stars). The HII LFs with L < $10^{37.1}\;erg\;s^{-1}$ are found to have different slopes for different parts in M51: the HII LF for the interarm region is steeper than those for the arm and the nuclear regions. This observed difference in HII LFs can be explained by evolutionary effects: HII regions in the interarm region are relatively older than those in the other parts of M51. The size distribution of the HII regions is fitted by a double power law with a break at D = 30 pc. The power law index for the small HII regions with 15 pc < D < 30 pc is ${\alpha}=-1.78{\pm}0.04$, whereas ${\alpha}=-5.04{\pm}0.08$ for the large HII region with 30 pc < D < 110 pc. The power law indices of the size distribution are related with those of HII LF, and the relation between the luminosities and sizes of HII regions is fitted well by $L{\propto}D^{3.04{\pm}}$.

• Korean Chemical Engineering Research
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• v.48 no.6
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• pp.673-678
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• 2010

In the present study, mixed carbon-supported platinum(Pt) nanoparticles were prepared by a chemical reduction method of Pt precursor solution on two types of carbon materials such as activated carbons(ACs) and graphite nanofibers(GNFs). Average crystalline sizes and loading levels of Pt metal particles could be controlled by changing a content of GNFs. The highest electroactivity for methanol oxidation was obtained by preparing the carbon supports having 15 wt% GNFs. Furthermore, with an increase of GNFs content from 0% to 15%, an electrical conductivity was changed from $10^{-4}S/cm$ to $10^{-1}S/cm$. By an introduction of 10 wt% GNFs additive, the electroactivity of platinum particles was enhanced, but was saturated in the case of 15 wt% GNFs contents. This was related with the fact that the electroactivity change was dependent on the electrical conductivity of mixed carbon supports and Pt particle deposition content or deposition morphology.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.54.1-54.1
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• 2014

Kyung Hee University has been developing a CubeSat for the space science mission called SIGMA (Scientific cubesat with Instrument for Global Magnetic field and rAdiation), which includes TEPC (Tissue Equivalent Proportional Counter) and a magnetometer. SIGMA has a 3-unit CubeSat, and the weight is about 3.2 kg. The main payload is TEPC which can measure the Linear Energy Transfer (LET) spectrum and calculate the equivalent dose for the complicated radiation field in the space. The magnetometer is a secondary payload using a miniaturized fluxgate magnetometer. We expect it to have a 1 nT resolution in the dynamic range of ${\pm}65535$ nT. An Attitude Control System (ACS) spins the SIGMA spacecraft 4 rpm with the spin axis perpendicular to the ecliptic plane. Full duplex communication is consists of VHF uplink and S-band and UHF downlink. In this paper, we introduce the system design and the scientific purpose of the SIGMA CubeSat mission.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.39.1-39.1
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• 2014

We present the results of our analysis of the RR Lyrae (RRL) variable stars detected in two transition-type dwarf galaxies (dTrans), ESO294-G010 and ESO410-G005 in the Sculptor group, which is known to be one of the closest neighboring galaxy groups to our Local Group. Using deep archival images from the Advanced Camera for Surveys (ACS) onboard the Hubble Space Telescope (HST), we have identified a sample of RR Lyrae candidates in both dTrans galaxies [219 RRab (RR0) and 13 RRc (RR1) variables in ESO294-G010; 225 RRab and 44 RRc stars in ESO410-G005]. The metallicities of the individual RRab stars are calculated via the period-amplitude-[Fe/H] relation derived by Alcock et al. This yields mean metallicities of <[Fe/H]>_{ESO294} = -1.77 +/- 0.03 and <[Fe/H]>_{ESO410} = -1.64+/- 0.03. The RRL metallicity distribution functions (MDFs) are investigated further via simple chemical evolution models; these reveal the relics of the early chemical enrichment processes for these two dTrans galaxies. In the case of both galaxies, the shapes of the RRL MDFs are well-described by pre-enrichment models. This suggests two possible channels for the early chemical evolution for these Sculptor group dTrans galaxies: 1) The ancient stellar populations of our target dwarf galaxies might have formed from the star forming gas which was already enriched through "prompt initial enrichment" or an "initial nucleosynthetic spike" from the very first massive stars, or 2) this pre-enrichment state might have been achieved by the end products from more evolved systems of their nearest neighbor, NGC 55.

• Proceedings of the SCSK Conference
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• 1999.10a
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• pp.132-132
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• 1999

In the cosmetics field, facial skins have been classified into four types according to self estimation as well as physiological parameters. The aim of this study is to understand skin condition in the levels and composition of stratum corneum (SC) lipids, and to propose new classification for skin types. We assessed the relationship between the SC lipid composition and the self-estimated skin types or physiological parameters of the skin. Sensitive skin has been of great concern over the last decades, and it should be recognized as a skin type. Therefore, we also investigated the influence of the SC lipid composition on variations of sensitivity evaluated by the Stinging Test. Fifty-five healthy Japanese women aged 22-44 participated in this study. Skin biopsies were taken from facial skin using polyethylene sheet with cyanoacrylate. SC lipids were extracted and separated into individual lipid classes. The combined ceramides and cholesterol were quantified by HPTLC. Free fatty acid was quantified according to the ACS-ACOD method. Instrumental measurements were made at the site around the biopsy. In addition, the Stinging Test and a sensory evaluation questionnaire were administered to all subjects. The generally recognized O-D skin type classification is dependent on the consumer`s subjective assessment with respect to their skin troubles. The product of hydration state and skin surface lipid level showed a significant correlation with self-estimated skin types. The oily-dry skin type classified according to physiological parameters as well as SC lipid levels should be characterized as delicate skin with its barrier function deteriorating in the winter. Two groups of sensitive skin were established. One is the barrier function of the skin is deteriorated, and another is the sebaceous gland activity is in decline.