• Korean Journal of Microbiology
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• v.46 no.2
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• pp.134-139
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• 2010

Mycobacterium tuberculosis (Mtb) is one of the most successful pathogens to infect one third of world population. Th1-mediated immunity against Mtb infection is known as critical to express mycobacteriostatic function but it is not sufficient to resolve the infection. In this study, to verify the possibility Mtb itself change the gene expression to survive against host immune response, expression pattern of selected H37Rv genes, 16S rRNA, acr, fbpA, aceA, and ahpC, during the course of infection was measured with absolute quantitation method using real-time RT-PCR. The total number of transcripts of 16S rRNA increased during the course of infection, which was coincide with the increasing CFU. The total number of fbpA transcripts per CFU, which encode typical secreted Mtb antigen, Ag85A, increased for 10 days of infection before decreasing. The number of transcripts of acr per CFU, which encode heat shock protein, ${\alpha}$-crystallin, increased during the infection, and ahpC and aceA, they both are enzymes produced in oxidative stressful condition, increased for 20 days and then slightly decreased on day 30. These findings are one of survival strategy of pathogen evading host immune response lead to persistent infection inside host cells.

• Journal of the Institute of Electronics and Information Engineers
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• v.54 no.6
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• pp.55-64
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• 2017

High-capacity, high-definition image applications need to process considerable amounts of data at high speed. Accordingly, users of these applications demand a high-speed parallel execution system. To increase the speed of a parallel execution system, Park (2004) proposed a technique, called MAMS (Multi-Access Memory System), to access data in several execution units without the conflict of parallel processing memories. Since then, many studies on MAMS have been conducted, furthering the technique to MAMS-PP16 and MAMS-PP64, among others. As a memory architecture for parallel processing, MAMS must be constructed in one chip; therefore, a method to achieve the identical functionality as the existing MAMS while minimizing the architecture needs to be studied. This study proposes a method of miniaturizing the MAMS architecture in which the architectures of the ACR (Address Calculation and Routing) circuit and MMS (Memory Module Selection) circuit, which deliver data in memories to parallel execution units (PEs), do not use the MMS circuit, but are constructed as one shift and conditional statements whose number is the same as that of memory modules inside the ACR circuit. To verify the performance of the realized architecture, the study conducted the processing time of the proposed MAMS-PP64 through an image correlation test, the results of which demonstrated that the ratio of the image correlation from the proposed architecture was improved by 1.05 on average.

• Korean Chemical Engineering Research
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• v.51 no.3
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• pp.335-341
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• 2013

Ammonia circulation reactor (ACR) was devised for the effective pretreatment of corn stover. This method is designed to circulate aqueous ammonia continuously so that it can reduce the chemical and water consumption during pretreatment. In this study, ammonia pretreatment with various reaction conditions such as reaction time (4~12 hour), temperature ($60{\sim}80^{\circ}C$), and solid:liquid ratio (1:3~1:8) was tested. Chemical compositions including solid remaining after reaction, lignin and carbohydrates were analyzed and enzymatic digestibility was also measured. It was observed that as reaction conditions become more severe, lignin removal was significantly affected, which was in the range of 47.6~70.6%. On the other hands, glucan and xylan losses were not substantial as compared to that of lignin. At all tested conditions, the glucan loss was not changed substantially, which was between 4.7% and 15.2%, while the xylan loss varied, which was between 7.4% and 25.8%. With (15 FPU-GC220+30 CBU)/g-glucan of enzyme loading, corn stover treated using ammonia circulation reactor for 8~12 hours resulted in 90.1~94.5% of 72-h glucan digestibility, which was higher than 92.7% of $Avicel^{(R)}$-101. In addition, initial hydrolysis rate (at 24 hour) of this treated corn stover was 73.0~79.4%, which was shown to be much faster than 69.5% of $Avicel^{(R)}$-101. As reaction time increased, more lignin removal and it was assumed that the enhanced enzymatic digestibility of treated biomass was attributed to the lignin removal.

• Journal of the Korean Society of Radiology
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• v.17 no.6
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• pp.911-917
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• 2023

The method of observing nodular changes on the liver surface using clinical ultrasonography is useful for diagnosing cirrhosis. However, the speckle noise that inevitably occurs in ultrasound images makes it difficult to identify changes in the liver surface and echo patterns, which has a negative impact on the diagnosis of cirrhosis. The purpose of this study is to model the median modified Wiener filter (MMWF), which can efficiently reduce noise in cirrhotic ultrasound images, and confirm its applicability. Ultrasound images were acquired using an ACR phantom and an actual cirrhotic patient, and the proposed MMWF algorithm and conventional noise reduction algorithm were applied to each image. Coefficient of variation (COV) and edge rise distance (ERD) were used as quantitative image quality evaluation factors for the acquired ultrasound images. We confirmed that the MMWF algorithm improved both COV and ERD values compared to the conventional noise reduction algorithm in both ACR phantom and real ultrasound images of cirrhotic patients. In conclusion, the proposed MMWF algorithm is expected to contribute to improving the diagnosis rate of cirrhosis patients by reducing the noise level and improving spatial resolution at the same time.

• Proceedings of the Korean Magnestics Society Conference
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• 2008.12a
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• pp.81.1-81.1
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• 2008

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.6B
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• pp.334-341
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• 2007

A Mobile IP is considered for the efficient mobility function in IEEE 802.16/WiBro environment. However, during the deployment of WiBro, only some of the ACRs(Access Control Router) can support the Mobile IP function. Therefore, a WiBro network can not support the mobility function for the mobile node. In this paper, we implement an overlay-based Mobile IP function and measure the performance through a field trial. Moreover, we evaluate the possibility of commercial deployment and suggest areas that need to be improved.

• Journal of the Korea Computer Industry Society
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• v.2 no.4
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• pp.547-564
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• 2001

In this paper a simulation has been performed to compare and evaluate the performance between the EPRCA(Enhanced Proportional Rate Control Algorithm) and EMRCA(Explicit Max_min Rate Control Algorithm) switches. The variation of the ACR at the source end system, the queue length, the utilization rate of the link bandwidth and the share fairness at the transient and steady states are used as the evaluation criteria for the simulation. The EMRCA switch is more stable than the EPRCA switch and reduces its buffer size. Also, it achieves a higher utilization rate of the link bandwidth than the EPRCA switch. The hardware complexity of the EMRCA switch is significantly lower than the EPRCA and other rate-based switches. Since it eliminates the necessity of the floating-point operation for calculation of the MACR(Mean Allowed Cell Rate) at the switch.

• Journal of Korean Medicine Rehabilitation
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• v.26 no.4
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• pp.127-136
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• 2016

The purpose of this study is to report a clinical progress of fibromyalgia syndrom patient treated by Korean Medicine treatment. The patient was treated with acupuncture, acupotomy, pharmacopuncture (Bee venom, Hwangryun, Hominis Placental), herbal medicine, moxibustion, cupping treatment. We measured Visual Analogue Scale (VAS), American College of Rheumatology Preliminary Diagnostic Criteria (ACR, 2010), Fibromyalgia Impact Qustionnaire (FIQ), and observed the change in body temperature using Digital Infrared Thermal Imaging (DITI). After Korean Medicine treatment, pain was controlled and VAS, ACR, FIQ were decreased. The result showed that Korean Medicine treatment is effective in fibromyalgia syndrome.

• Journal of the Korean Applied Science and Technology
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• v.18 no.4
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• pp.261-272
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• 2001

An ACR/HMMM film was prepared by blending high-solid ACR with curing agent, hexamethoxymethyl melamine (HMMM). An active curing reaction was observed at $170^{\circ}C$. The dynamic viscoelastic $T_{g}$ of the final film increased with the static viscoelastic $T_{g}$ of the film. The log damp value, which means a viscoelastic ratio, decreased with the increase in the curing temperature of the film. Physical properties of the films were within a suitable range for films, and by an accelerated weathering resistance test the films were proved weather resistible ones.

• YAKHAK HOEJI
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• v.60 no.1
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• pp.1-7
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• 2016

The aim of this study was to investigate the prevalence of quinolone resistant E. coli from retail meat and to characterize the resistant determinants. Determination of minimum inhibitory concentration, the sequence analysis of gyrA, gyrB, parC, and parE quinolone resistance determining regions (QRDR), the presences of plasmid mediated quinolone resistance (PMQR) and the expression of efflux pump genes were investigated. Of the total 277 retail meat samples, 67 coli form bacteria were isolated. 15 of 67 isolates showed nalidixic acid resistance and 7 of 15 nalidixic acid resistant isolates were also resistant to ciprofloxacin, moxifloxacin and levofloxacin. 11 of 15 nalidixic acid resistant strains were isolated from chicken, 2 of 15 were isolated from beef and 2 of 15 were isolated from pork samples. 11 of 15 nalidixic acid resistant strains have single mutation at codon 87 (D87N or D87G) in gyrA, 2 of 11 gyrA mutants have double mutations at codon 86 and 87 (L86A and L87I) in parC with mutations at codon 434+445+465 or 429 in gyrB. 2 of 15 resistant isolates harbored qnrS, a PMQR determinant. Over expression of the acrB gene, efflux pump gene (3.93~16.53 fold), was observed in 10 of 15 resistant isolates.