• Asian-Australasian Journal of Animal Sciences
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• v.25 no.8
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• pp.1159-1168
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• 2012

The experiment was carried out to investigate the effects of Alisma canaliculatum with probiotics (ACP) on the growth performance, meat composition, oxidative stability, and fatty acid composition of broiler meat. Sixteen probiotic strains were tested for their levels of acid, bile, and heat tolerance. Among them, Lactobacillus acidophilus KCTC 3111, Enterococcus faecium KCTC 2022, Bacillus subtilis KCTC 3239, and Saccharomyces cerevisiae KCTC 7928 were selected for use in ACP. Exactly 140 Ross broiler chicks were assigned to four dietary treatments in five replications for 5 wks in a completely randomized design. The dietary treatments were NC (Negative control; basal diet), PC (Positive control; basal diet with 0.005% Chlortetracycline), ACP-0.5% (basal diet with 0.5% ACP powder), and ACP-1% (basal diet with 1% ACP powder). According to the results, body weight of the broilers increased, and feed conversion ratio improved in the ACP-0.5% group compared to the NC group (p<0.05). Crude protein content of breast meat was higher (p<0.05) in the ACP-0.5% group, whereas crude fat content of thigh meat was lower (p<0.05) in the supplemented groups. Breast meat absolute and relative weights were both higher (p<0.05) in the ACP groups compared to the control group. Further, ACP diets increased gizzard and decreased large intestine relative weights, whereas kidney relative weight decreased upon the addition of a higher level (1%) of ACP (p<0.05). Thiobarbituric acid reactive substances values of breast and thigh meats were reduced (p<0.05) by ACP supplementation compared to control. Regarding the fatty acid composition of breast meat, arachidonic acid, docosahexaenoic acid, PUFA, and n6 fatty acid levels decreased (p<0.05) in the ACP groups, whereas the levels of linoleic acid, PUFA, PUFA/SFA, and n6 fatty acid in thigh meat decreased (p<0.05) by ACP and PC diets. It can be suggested based on the study results that ACP-0.5% diet could be an effective feed additive for broilers.

• YAKHAK HOEJI
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• v.43 no.4
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• pp.423-428
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• 1999

Two polysaccharides, ACP-UMP and ACP-ULF, were purified from the aerial part of Artemisia capillaris by anion-exchange chromatography, ultrafiltration, and gel filtration chromatography. The polysaccharides appeared to be homogenious from the results of HPLC. The molecular weights of ACP-UMF and ACP-ULF were estimated to be 16305.92 D and 3292.26 D, respectively, by MALDI-TOF MS. The sugar compositions were determined by GC to be arabinose 10.05%, xylose 1.67%, mannose 5.45G, galactose 39.06%, glucose 15.43% for ACP-UMF and arabinose 11.60%, xylose 11.15%, mannose 6.37% galactose 32.47%, glucose 18.35% for ACP-ULF. A polysaccharide, SP-M was determined to be 2462.52 D by MALDI-TOF MS. SP-M consisted mainly of rhamnose 36.49%, arabinose 29.00%, and glucose 19.38%. Incubation of CCl4-intoxicated hepatocytes with ACP-UMF reduced the levels of glutamic pyruvic transaminase (GPT) and cellular malondialdehyde (MDA) to 62.8% and 23.8%. ACP-ULF also reduced the levels of GPT and MDA to 46.1% and 38.1% and 26.3%, respectively.

• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.1
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• pp.13-23
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• 2018

This study was performed to investigate the antioxidant and antidyslipidemic effects of Artemisiae iwayomogii Herba, Curcumae longae Radix and Plantaginis Semen complex extract(ACP) on HepG2 cells. We measured total polyphenols, total flavonoids, radical scavenging activity, and ABTS radical scavenging activity of ACP to evaluate its antioxidant activity. HepG2 cells were treated with ACP. Then, we evaluated ROS production; intracellular GSH content; GPx, GR, SOD, and catalase activities; free fatty acids and MDA levels; and mRNA expression levels of ACAT1 and HMG-CoA reductase. Results: ACP contains polyphenols and flavonoids and increased the DPPH and ABTS radical scavenging activities in HepG2 cells in a dose dependent manner. Also, ACP significantly reduced ROS production in HepG2 cells compared to the control group and significantly increased the GSH content, and elevated the enzyme activities of GPx, GR, and catalase in HepG2 cells compared to the control group. In addition, ACP reduced the mRNA expression of ACAT1 and HMG-CoA reductase in HepG2 cells compared to that in the control group. Conclusion: These results suggest that ACP has an antioxidant effect and may suppress the expression of dyslipidemia - associated genes and thus may be useful for the improvement of dyslipidemia.

• Journal of Korean society of Dental Hygiene
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• v.8 no.1
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• pp.13-22
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• 2008

This study compared tooth's remineralization using enamel surface artificially demineralized with 0.1M lactate and HCL solution using Vicker's Hardness Number(VHN) to compare CPP-ACP and remineralization of nano-sized Carbonate Apatite's initial caries. Using pH circulation models divided into 0% nano-CA, 5% nano-CA, 10% nano-CA, 10% CPP-ACP and D.W. they were treated for 5 minutes, three times a day for 14 days to get the following results. 1. There were no significant differences among the initial surface hardness of samples demineralized surface of front tooth in 5 groups. and all 5 groups' surface hardness reduced significantly after demineralization of enamel. 2. When inquiring into hardness changes through pH circulation model, the highest hardness change was in 5% nano-CA group. Also. 10% nano-CA and 10% CPP-ACP groups increased significantly. but there was no significant difference statistically. In generalizing the above experiment results, nano-sized Carbonate Apatite showed remineralization, and compared to 10% CPP-ACP group, 5% nano-CA had remineralization to artificial caries. thus implies that when we develop method to contact with tooth of nano-CA in the future, it is expected to gain synergy effect on function of saliva, a natural remineralization material.

• Korean Journal of Plant Resources
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• v.2 no.2
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• pp.312-318
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• 1989

가을무우의 궁중 무우 6품종 및 연마무우 4품종에 관하여 Acp, NDH 및 IDH의 다형적변이를 조사하였다. 1. Acp에서는 7개의 Band가 (PH 7.0~8.0),NH에서는 2개의 Band가 (PH7.5~8.0) IDH에서는 3개의 Band가 (PH 5.0~6.0) 검출되었다. 2.Acp-1, -2, -3, -5 및 -6의 band, NDH-2의 Band 및 IDH-2의 Band 가 전품조에서 고정적인 Band로 검축되었다. 3.궁중군에서는 NDH-1, Acp-4 의 Band가 전혀 검출되지 않았다. 4. 다형적인 변이가 보여진 Acp-4 및 -7, NDH-1, IDH-1 및 -3의 5가지의 Band에서 품종판별로 Marker로 활용할 수 있음이 밝혀졌다.

• Journal of Hospice and Palliative Care
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• v.24 no.3
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• pp.144-153
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• 2021

Purpose: Advance care planning (ACP) is widely understood to improve end-of-life care. This systematic review and meta-analysis aimed to examine the effects of ACP interventions on decision conflict and psychological distress. Methods: A search of PubMed, CINAHL, CENTRAL, EMBASE, KISS, KoreaMed, and RISS was conducted in November 2020. The study included randomized controlled trials. Data were pooled using fixed- and random-effects models. Results: Fourteen studies were identified that cumulatively included 1,548 participants. ACP interventions were effective in alleviating decision conflict (d=-0.53; 95% CI: -0.83 to -0.23), depression (d=-1.22; 95% CI: -1.71 to -0.74) and anxiety (d=-0.76; 95% CI: -1.12 to -0.39). Conclusion: ACP interventions have significant positive effects on reducing decision conflict and psychological distress. A high level of bias was shown related to allocation concealment and blinding. The results of this study are expected to be useful for end-of-life care providers to improve the effectiveness of ACP interventions.

• Journal of the Korea Convergence Society
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• v.7 no.6
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• pp.133-139
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• 2016

This study was to evaluate the change of mineral loss of fTCP and CPP-ACP in artificial caries lesions using QLF-D to compare the remineralization effect of recently developed fTCP and CPP-ACP, which is widely used as a remineralization cream in current dental clinics. Bovine specimens used in this study formed the artificial caries lesion immersing in demineralization solution for 10 days and were divided randomly into the following two groups; Group 1- Tooth Mousse containing 10% CPP-ACP, Group 2- Clinpro Tooth Creme containing 950ppm NaF and fTCP. Two tooth paste were applied to the artificial caries lesion of specimens and they were immersed in artificial saliva for 1 week. Mineral loss of artificial caries lesion was evaluated by fluorescence loss (${\Delta}F$) values using QLF-D. QLF-D analysis showed that the ${\Delta}F$ and ${\Delta}Fmax$ value increased 2.65 and 6.63, respectively, in the Tooth Mousse group, and the mineral loss decreased statistically significantly(p<0.05). However, Clinpro Tooth Creme group had no statistically significant difference. ${\Delta}Fmax$ value of Tooth Mousse group was statistically significant difference compared to the Clinpro Tooth Creme. Therefore, the Tooth Mousse containing 10% CPP-ACP is more effective than Clinpro Tooth Creme containing fTCP in the treatment of remineralization of artificial caries lesions.

• Journal of Sericultural and Entomological Science
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• v.53 no.1
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• pp.44-49
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• 2015

We characterized tissue specific-expressed genes in the posterior silk gland of Bombyx mori using by the Annealing Control Primer based differential display-PCR manner. In this study, we isolated 34 differentially expressed PCR amplicons, which one of these was identified as a novel transcript named as ACP-16 (366 bp), its expression was observed only in the posterior silk glands by Northern blot analysis. To determine promoter region of the ACP-16, we isolated and analyzed a phage DNA having 1.7 kb-long genome DNA including the open reading flame and 5'- upstream untranslated region of the ACP-16 gene from a genomic DNA library. We have estimated a promoter region of the ACP-16 gene by a web promoter prediction engine, which locates -750 ~ -165 from translation initiation site (ATG, +1). ACP-16 gene is necessary to more studies about critical biological role in order to apply the silkworm's transgenic system.

• Journal of Korean Society of Forest Science
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• v.68 no.1
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• pp.32-36
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• 1985

Megagametophyte tissues of Pinus densiflora were subjected to study the inheritance of acid phosphatase (ACP), alcohol dehydrogenase (ADH) and catalase (CAT) isozymes by starch gel zone-electrophoresis. At least three or four zones were segregated for ACP isozyme. However, as one isozyme of ACP-A zone was separated clearly, only that isozyme was analysed. Five isozyme phenotypes (A1-A5), observed in ACP-A zone, were segregated to a simple Mendelian ratio, suggesting that these are controlled by five codominant alleles existed at ACP-A locus. Two zones of activity were segregated in the gels after staining for ADH, the more anodal zone (ADH-A) of the two was invariant in our materials. Three isozyme phenotypes (B1-B3) were observed in ADH-B zone and these variants showed a 1:1 segregation pattern, suggesting that each variant is controlled by three codominant alleles at ADH-B locus. A total of five isozyme phenotypes, composed of multiple bands, were observed in CAT isozyme. The segregation of these phenotypes in heterozygous trees did not show any significant deviation from a 1:1 segregation. Therefore, the genetic control of CAT isozyme in Pinus densiflora seeds seems to be based on a single locus (CAT-A) with Five codominant alleles ($A_1-A_5$).

• The korean journal of orthodontics
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• v.43 no.1
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• pp.23-28
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• 2013

Objective: The purpose of this study was to evaluate the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) on the shear bond strength (SBS) of brackets bonded to non-demineralized teeth with either phosphoric acid etching or self-etching primer. Methods: Sixty human premolars were randomly assigned to 1 of 4 treatment groups (n = 15 each): phosphoric acid etching (group 1); self-etching primer (group 2); CPP-ACP for 2 weeks + phosphoric acid etching (group 3), and CPP-ACP for 2 weeks + self-etching primer (group 4). After bonding of the maxillary premolar metal brackets, specimens were subjected to shear forces in a testing machine. Scanning electron microscopy was used to observe etching patterns on the enamel surfaces of all teeth. A 2-way analysis of variance was used to test for effects of CPP-ACP and etching system on SBS. Results: Significantly higher mean SBSs were observed in groups subjected to phosphoric acid etching (i.e., groups 1 and 3; p < 0.05). On the other hand, SBSs did not appear to be influenced by CPP-ACP (i.e., groups 3 and 4; p > 0.05). We observed a uniform and clear etched pattern on the enamel surface of the phosphoric acid etching groups. Conclusions: CPP-ACP does not significantly affect the SBS of orthodontic brackets bonded to non-demineralized teeth, regardless of which adhesive method is used to bond the brackets.