• Title/Summary/Keyword: AC stress

Search Result 259, Processing Time 0.023 seconds

Anti-ulcer effects of HT074 on HCl/EtOH induced gastric injury (염산/에탄올로 유도된 위손상 동물모델에서 HT074의 항궤양 효과)

  • Kim, Young-Sik;Park, HyoJin;Song, Jungbin;Lee, Donghun;Kim, Hocheol
    • The Korea Journal of Herbology
    • /
    • v.33 no.4
    • /
    • pp.9-18
    • /
    • 2018
  • Objectives : This study aimed to investigate the anti-ulcer effect of an standardized herbal extracts mixture of Inulae Flos and Paeoniae Radix (HT074) on acidified ethanol induced gastric injury and its potential mechanisms. Methods : Antioxidant activities of HT074 and its constituents were measured by DPPH (2,2-Diphenyl-1-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging capacity. After the oral administration of HT074 at doses of 100, 300 mg/kg twice per day for 14 days, Gastric lesions were induced by oral administration of acidified ethanol in Sprague Dawley rats. Oxidative stress markers, such as super oxide dismutase (SOD) activity, concentrations of catalase (CAT) and glutathione (GSH) were measured in gastric mucosal tissues. Additionally, the expression of human mucin gene, Mucin 5AC (MUC5AC) mRNA in gastric mucosal tissues was measured. Results : HT074 showed dose dependent radical scavenging activities against DPPH and ABTS radicals. Oral administration of HT074 300 mg/kg for 14 consecutive days significantly decreased gastric lesions and histological damages induced by HCl/EtOH in rats. HT074 treatment significantly increased the activity of SOD (300 mg/kg) and concentration of GSH (100 and 300 mg/kg), however catalase concentration was not significantly increased. MUC5AC mRNA expression was significantly increased by HT074 100, 300 mg/kg treatment. Conclusions : HT074 protects the gastric mucosa from oxidative stress caused by acidified ethanol by increasing the activity of SOD, concentration of GSH and mucin biosynthesis. These findings suggest that HT074 could be an effective candidate for prevention and treatment of gastritis and gastric ulcer.

Comparison of the High Concentration Calcium Chloride(CaCl2) Salt Reduction Effect of Soil Amendment Agent and Planting Pennisetum alopecuroides (토양개량제와 수크령 식재에 따른 고농도 염화칼슘 염분저감 효과 비교)

  • Yang, Ji;Park, Jae-Hyeon;Yoon, Yong-Han;Ju, Jin-Hee
    • Korean Journal of Environment and Ecology
    • /
    • v.34 no.4
    • /
    • pp.345-354
    • /
    • 2020
  • The purpose of this study was to investigate the effects of soil amendment treatments, such as hydroball, and active carbon, and planting Pennisetum alopecuroides for reducing calcium chloride (CaCl2) of soil leachate and the growth of Pennisetum alopecuroides. The experiment planted Pennisetum alopecuroides in a plastic pot with a diameter of 10 cm and a height of 9 cm in a greenhouse April-October 2018. The experimental group comprised six treatments, including Non-treatment (Cont.), Hydroball (H), Active carbon (AC), planting Pennisetum alopecuroides (P), hydroball + planting Pennisetum alopecuroides (H + P), and active carbon + planting Pennisetum alopecuroides (AC + P). The dissolution of the CaCl2 concentration 200ml of 10g/L was irrigated once every two weeks. We measured the growth (plant height, leaf length, leaf width, number of leaves), EC, pH, and exchangeable cations (K+, Ca2+, Na+, and Mg2+) according to the high concentration of CaCl2 in the plant and soil leachate. In a treatment with the 'hydroball' amendment, the soil leachate electrical conductivity (EC), and the cation exchangeable were decreased more than those of the control, while the growth of Pennisetum alopecuroides relative growth rate(RGR) increased. Overall, application with the hydroball amendment added the planting of Pennisetum alopecuroides improved the salt reduction effect more than the control group. These results indicate that the application of the soil amendment agent hydroball was suitable soil amendments in accordance with the high concentration of calcium chloride (CaCl2). Also, Planting Pennisetum alopecuroides is expected to be appropriate for salt-tolerant plant for soil affected by deicing salt agents.

Antihyperglycemic of Gleditschiae Spina Extracts in Streptozotocin-Nicotinamide Induced Type 2 Diabetic Rats (Streptozotocin-Nicotinamide로 유도된 제2형 당뇨모델 쥐에서 조각자(Gleditschiae Spina) 추출물의 항당뇨효과)

  • Park, Jae-Hee;Chu, Won-Mi;Lee, Jeung-Min;Park, Hae-Ryong;Park, Eun-Ju
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.40 no.2
    • /
    • pp.321-326
    • /
    • 2011
  • The aim of the present study was to investigate antihyperglycemic effect of Gleditschiae Spina (GS) in streptozotocin (STZ)-nicotinamide (NA)-induced type 2 diabetic rats. The rats were divided into four groups: normal control (NC), diabetic control (DC), diabetic rats supplemented with acarbose (AC, 4 mg/kg), and with GS ethanol extracts (GSE, 50 mg/kg). Weekly fasting blood glucose (FBG) for 10 weeks and oral glucose tolerance test (OGTT) at 10th week were monitored using glucose oxidase-peroxidase reactive strips. The FBG level was significantly reduced in AC group after 8 weeks and in GSE group at the end of period. The AUCs for the glucose response from OGTT and blood glucose level after sacrifice were significantly lower in the AC and GSE groups than the DC group. GSE supplementation significantly increased plasma total radical-trapping antioxidant potential (TRAP) in STZ-NA-induced diabetic rats, compared with DC group. The present study indicates that GSE could ameliorate type 2 diabetes and be comparable to acarbose, a standard hypoglycemic drug. Also, we suggest that GSE may possess antioxidant activity against the STZ-NA-induced oxidative stress.

The reliability physics of SiGe hetero-junction bipolar transistors (실리콘-게르마늄 이종접합 바이폴라 트랜지스터의 신뢰성 현상)

  • 이승윤;박찬우;김상훈;이상흥;강진영;조경익
    • Journal of the Korean Vacuum Society
    • /
    • v.12 no.4
    • /
    • pp.239-250
    • /
    • 2003
  • The reliability degradation phenomena in the SiGe hetero-junction bipolar transistor (HBT) are investigated in this review. In the case of the SiGe HBT the decrease of the current gain, the degradation of the AC characteristics, and the offset voltage are frequently observed, which are attributed to the emitter-base reverse bias voltage stress, the transient enhanced diffusion, and the deterioration of the base-collector junction due to the fluctuation in fabrication process, respectively. The reverse-bias stress on the emitter-base junction causes the recombination current to rise, increasing the base current and degrading the current gain, because hot carriers formed by the high electric field at the junction periphery generate charged traps at the silicon-oxide interface and within the oxide region. Because of the enhanced diffusion of the dopants in the intrinsic base induced by the extrinsic base implantation, the shorter distance between the emitter-base junction and the extrinsic base than a critical measure leads to the reduction of the cut-off frequency ($f_t$) of the device. If the energy of the extrinsic base implantation is insufficient, the turn-on voltage of the collector-base junction becomes low, in the result, the offset voltage appears on the current-voltage curve.

A ZVS Resonant Converter with Balanced Flying Capacitors

  • Lin, Bor-Ren;Chen, Zih-Yong
    • Journal of Power Electronics
    • /
    • v.15 no.5
    • /
    • pp.1190-1199
    • /
    • 2015
  • This paper presents a new resonant converter to achieve the soft switching of power devices. Two full-bridge converters are connected in series to clamp the voltage stress of power switches at Vin/2. Thus, power MOSFETs with a 500V voltage rating can be used for 800V input voltage applications. Two flying capacitors are connected on the AC side of the two full-bridge converters to automatically balance the two split input capacitor voltages in every switching cycle. Two resonant tanks are used in the proposed converter to share the load current and to reduce the current stress of the passive and active components. If the switching frequency is less than the series resonant frequency of the resonant tanks, the power MOSFETs can be turned on under zero voltage switching, and the rectifier diodes can be turned off under zero current switching. The switching losses on the power MOSFETs are reduced and the reverse recovery loss is improved. Experiments with a 1.5kW prototype are provided to demonstrate the performance of the proposed converter.

Filtering Techniques to Reduce the Transient Voltage of High Voltage Induction Motor on H-bridge cascaded 7- level Inverte (H-Bridge 7-레벨 인버터 구동시 고압 유도전동기에서 발생하는 과도전압 저감을 위한 필터기술)

  • Kwon, Young-Mok;Kim, Jae-Chul;Kim, Young-Sung;Lee, Yang-Jin
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
    • /
    • 2005.05a
    • /
    • pp.47-50
    • /
    • 2005
  • In this paper, we investigate a filtering technique to reduce the adverse effect of long motor leads on H-bridge cascaded 7-level inverter fed ac motor drive. The switching surge voltage becomes the major cause to occur the insulation failure by serious voltage stress in the stator winding of high voltage induction motor. However, the effect of switching surge appears un seriousin high voltage induction motor than low voltage induction motor. Consequently, we demonstrated that the filter connected to the motor terminals greatly reduces the transient voltage stress and ringing, moreover we show lowers the dv/dt of the inverter switching pulse. The results of simulation show the suppression of dv/dt and the reduced peak voltage at the motor end of a long cable.

  • PDF

Design of the LLC Half Bridge Resonant Adapter for Notebook Computers (노트북 컴퓨터용 LLC 하프 브리지 공진형 어댑터 설계)

  • Hwang, Gook-Hwa;Youn, Dae-Young;Kim, Chang-Sun
    • Proceedings of the KIEE Conference
    • /
    • 2006.07b
    • /
    • pp.1039-1040
    • /
    • 2006
  • The resonant converters cause the high voltage stress according to the input voltage, which increases the conduction loss in converter power switches. The topology of LLC half bridge resonant converter provides ZVS characteristic and also the stress of voltage and current is not higher than that of the general resonant converters. So we can expect the higher efficiency. In this paper, the LLC resonant converter is designed for the notebook computer adapter. In the adapter design, we should consider the weight, the size and overheat of the adapter. Thus the higher efficiency is an essential particular. First of all, the optimal design of transformer is the most important facts. Some parameters should be considered in order to get the highest efficiency. The adapter is designed through the considering of these parameters including the PFC circuit of the pre-regulator. It converts AC line input into about $400V_{DC}$ Link voltage of the LLC converter input and the converter has $16V_{DC}/90W$ ratings. The efficiency measured is about up to 92%.

  • PDF

A Study on Stress and Deformation through Finite Element Analysis of 2NC Head Processing Controlling AC Axis during 5-Axis Cutting Machine Training in the 4th Industrial Revolution of Machine Tool System (공작기계의 4차 산업혁명에서 5축 절삭가공기 교육 중 AC축을 제어하는 2NC 헤드 가공상의 유한요소 해석으로 응력 및 변형에 관한 연구)

  • Lee, Ji Woong
    • Journal of Practical Engineering Education
    • /
    • v.13 no.2
    • /
    • pp.327-332
    • /
    • 2021
  • Materials used for education include SM20C, Al6061, and acrylic. SM20C materials are used a lot in certification tests and functional competitions as carbon steel, but they are also used in industrial sites. Al6061 is said to be a material that produces a lot of tools because it has lower hardness than carbon steel and is highly flexible. When practical guidance is given to students using acrylic materials, it is a material that causes vibration and tool damage due to excessive cutting. In this process, we examine how impact on the 5-axis equipment 2NC head can affect precision control. The weakest part of a five-axis equipment is the head that controls the AC axis. In the event of precision and cumulative tolerances in this area, the precision of all products is reduced. Thus, a key part of the 2NC head, the spindle housing was carried out using Al7075 T6 (U.S. Alcoasa) material and the entire body using FCD450 (spherical graphite cast iron). In the vibration and cutting process acting on these two materials, the analysis was carried out to determine the value of applying the force as a finite element analysis under extreme conditions. We hope that using these analytical data will help students see and understand the structure of 5-axis machining rather than 5-axis cutting.

Stress characteristics of multilayer polysilicon for the fabrication of micro resonators (마이크로 공진 구조체 제작을 위한 다층 폴리실리콘의 스트레스 특성)

  • Choi, C.A.;Lee, C.S.;Jang, W.I.;Hong, Y.S.;Lee, J.H.;Sohn, B.K.
    • Journal of Sensor Science and Technology
    • /
    • v.8 no.1
    • /
    • pp.53-62
    • /
    • 1999
  • Micro polysilicon actuators, which are widely used in the field of MEMS (Microelectromechanical System) technology, were fabricated using polysilicon thin layers. Polysilicon deposition were carried out to have symmetrical layer structures with a LPCVD (Low Pressure Chemical Vapor Deposition) system, and we have measured physical characteristics by micro test patterns, such as bridges and cantilevers to verify minimal mechanical stress and stress gradient in the polysilicon layers according to the methods of mutilayer deposition, doping, and thermal treatment, also, analyzed the properties of each specimen, which have a different process condition, by XRD, and SIMS etc.. Finally, the fabricated planar polysilicon resonator, symmetrically stacked to $6.5{\mu}m$ thickness, showed Q of 1270 and oscillation ampitude of $5{\mu}m$ under DC 15V, AC 0.05V, and 1000 mtorr pressure. The developed micro polysilicon resonator can be utilized to micro gyroscope and accelerometer sensor.

  • PDF

Effect of an Increased Wall Thickness on Delayed Hydride Cracking in Zr-2.5Nb Pressure Tube (Zr-2.5Nb 중수로 압력관의 수소지연파괴에 미치는 압력관 두께의 영향)

  • Jeong, Yong-Hwan;Kim, Young-Suk
    • Nuclear Engineering and Technology
    • /
    • v.27 no.2
    • /
    • pp.226-233
    • /
    • 1995
  • The wall thickness of a pressure tube is increased in order to reduce the probability of failure in a pressure tube of CANDU type reactor. It is presented here that the variation of wall thickness changes stress, hydrogen concentration and delayed hydride cracking in Zr-2.5Nb pressure tube. When the wall thickness is increased from 4.2 mm to 5.2 mm, the stress exerted on the tube and the deuterium taken up during operation are reduced by 19%. Further, the calculated allowable depth of the surface flaw over which delayed hydride cracking(DHC) is susceptible increases by 50%. DHC initiation is controlled by the stress and by the hydrogen concentration in the pressure tube. The results are therefore very significant in such a respect that increased wall thickness may reduce DHC initiation. Ac the wall thickness increases the hydrostatic tension will increase. Its impact on the acceleration of the crack growth rate of DHC deserves further studies.

  • PDF