• Title/Summary/Keyword: AC/A ratio

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Nitric Oxide Synthase 3 Gene Variants and Colorectal Cancer: a Meta-Analysis

  • Chen, Yang;Li, Jie;Guo, Yun;Guo, Xiao-Yun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3811-3815
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    • 2014
  • Background: Colorectal cancer (CRC) is the worldwide disease which causes enormous losses every year. Recent studies suggested that environmental and gene factors might be the etiologies in increasing the risk of morbidity. Nitric oxide synthase 3 (NOS3) gene polymorphisms are said to be associated with CRC risk but the conclusion is still controversial. Materials and Methods: Pubmed and HuGENet databases up to December 2013 were used in this meta-analysis. Three different certain genotypic models were applied, namely dominant (AA+AC versus CC), recessive (AA versus AC+CC), per-allele analysis (A vs C). In addition, information on tumor sites and pathologic stages was collected. The strength of associations was assessed through combining odds ratio (OR) and 95% confidence interval (CI). Results: Finally, five and three studies about the rs1799983 and rs2070744 were covered in the analysis with 2,745 cases and 2,478 controls. Three models were applied, but no significant association was found for NOS3 G894T/rs1799983 (dominant: OR=0.999, 95%CI=0.797-1.253, $I^2$=63.8%; recessive: OR=0.924, 95%CI=0.589-1.450, $I^2$=59.3%; allele analysis: OR=0.979, 95%CI=0.788-1.216, $I^2$=74.9%) and T-786C/rs2070744 (dominant: OR=1.138, 95%CI=0.846-1.530, $I^2$=67.9%; recessive: OR=0.956, 95%CI=0.708-1.291, $I^2$=0.0%; allele analysis: OR=1.110, 95%CI=0.865-1.425, $I^2$=69.4%). The same results were also obtained for tumor sites and pathologic stage subgroups. After further analyzing the NOS3 gene, rs1799983 as the tag- and functional SNP was presented. Conclusions: On the basis of this meta-analysis and the characteristics of the NOS3 gene, we suggested rs1799983 might be a key locus associated with CRC risk. Further prospective studies were needed to make more comprehensive explanation of the associations.

The Study on the Property of The Heterophoria and Fusional Reserve in Adults in Jeon-buk Area (전북지역 성인의 사위와 융합여력 특성에 관한 연구)

  • Oh, Hyun-Jin;Doo, Ha-Young;Sim, Sang-Hyun;Choi, Sun Mi;Oh, Seung-Jin
    • Journal of Digital Convergence
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    • v.11 no.11
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    • pp.661-666
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    • 2013
  • The aim of this study was to evaluate the property of heterophoria and fusional reserve in Adults in Jeon-buk Area. We examined the corrected visual acuity, corrected refractive error, heterophoria and fusional reserve of 116 healthy myopes aged from 20 to 44 old who had no strabismus no ocular and phyisical diseases. Using Von Graefe test of horizontal heterophoria Measurement, we measured orthophoria(26.7%), exophoria(52.5%) and esophoria(20.7%) for at near distance. The subjects who had exophoria of 0-6${\Delta}$ in the range of normal state was 38.8%, while the subjects who had exophoria in the range of abnormal state was 61.2%. Reducing fusional reserve was associated with increasing phoria. We found a relationship between asthenopia and fusional reserve of heterophoria and considered that fusional reserve must be examined when we preserve for a patient with heterophoria. Furthermore, Gradient method AC/A ratio was found 4.03 and its relationship to refractive error could not be determined.

Effect of Rheological Properties on the Sedimentation of Capsules in an Aqueous Polymer Solution (고분자 수용액의 레올러지 특성이 캡슐의 침강에 미치는 영향)

  • Kim, Dong-Joo;Kim, Jung-Ah;Kyong, Kee-Yeol;Yoon, Moung-Suk
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.1 s.49
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    • pp.85-89
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    • 2005
  • An aim of this study is to study the correlation between rheological properties and sedimentation of capsules in aqueous polymer solution with low viscosity. Rheological properties of aqueous polymer solutions were controlled by carbomer (C), acylate/C10-30 alkyl acylate crosspolymer (AC), and ammonium acryloyldimethyltaurate/VP copolymer (AV). Small amount of polymer C solution had the highest viscosity and yield stress of polymer AV solution was higher than that of polymer C solution in the same viscosity when the concentration of polymer AV exceeded $0.35 wt\%$. Each aqueous polymer solution was tested and the results showed that as viscosity and yield stress increased, the sedimentation ratio of capsules decreased. The viscoelasticity data also showed the same tendency in a shear stress range of 0.1 to 2.0 Pa. These results demonstrated that the rheological properties of polymer solutions had a strong correlation with the sedimentation of capsules. When polymer I and AV were used, there was a synergistic effect and the correlation between rheological properties and sedimentation of capsules was very complicated. It was assumed that the characteristics of polymer structure and interaction between polymers caused this phenomena.

The Electrochemical Characteristics of Hybrid Capacitor Prepared by Chemical Activation of NaOH (NaOH 화학적 활성화로 제조된 하이브리드 커패시터의 전기화학적 특성)

  • Choi, Jeong Eun;Bae, Ga Yeong;Yang, Jeong Min;Lee, Jong Dae
    • Korean Chemical Engineering Research
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    • v.51 no.3
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    • pp.308-312
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    • 2013
  • Active carbons with high specific surface area and micro pore structure were prepared from the coconut shell char using the chemical activation method of NaOH. The preparation process has been optimized through the analysis of experimental variables such as activating chemical agents to char ratio and the flow rate of gas during carbonization. The active carbons with the surface area (2,481 $m^2/g$) and mean pore size (2.32 nm) were obtained by chemical activation with NaOH. The electrochemical performances of hybrid capacitor were investigated using $LiMn_2O_4$, $LiCoO_2$ as the positive electrode and prepared active carbon as the negative electrode. The electrochemical behaviors of hybrid capacitor using organic electrolytes ($LiPF_6$, $TEABF_4$) were characterized by constant current charge/discharge, cyclic voltammetry, cycle and leakage tests. The hybrid capacitor using $LiMn_2O_4$/AC electrodes had better capacitance than other hybrid systems and was able to deliver a specific energy as high as 131 Wh/kg at a specific power of 1,448 W/kg.

Variation of Magnetic Properties of Fe-Si Compressed Cores with Si Content (Si 함량에 따른 Fe-Si 압분코어의 자기적 특성)

  • Jang, Pyung-Woo;Lee, Bong-Han;Choi, Gwang-Bo
    • Journal of the Korean Magnetics Society
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    • v.20 no.1
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    • pp.13-17
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    • 2010
  • Fe-3, 4.2 and 6.8% Si compressed cores were fabricated, and then electrical resistivity, AC and DC magnetic properties, microhardness, and other properties were analyzed in order to know whether best soft magnetic properties could be also obtained in an Fe-Si compressed core with the well-known composition of Fe-6.5% Si. With increasing the silicon content, eddy current loss and hysteresis loss decreased and increased, respectively, so that a minimum total loss was not obtained in the well-known Fe-6.8 % Si cores, but obtained in the Fe-4.2 % Si cores. Also electrical resistivity of the cores and hardness of the particles increased monotonously with silicon content so that compaction ratio of the cores decreased. B2 and $DO_3$ ordered phase could be observed only in Fe-6.8% Si powder. A minimum loss and highest permeability of the Fe-4.2 % Si cores can be explained by the ratio of specific electrical resistivity of insulator to that of magnetic particles, micro-hardness, compaction ratio and demagnetization coefficient of the Fe-Si powder particles with silicon content.

Association between the CYP1A2 rs762551 Polymorphism and Bladder Cancer Susceptibility: a Meta-Analysis Based on Case-Control Studies

  • Zeng, Yong;Jiang, Hua-Yong;Wei, Li;Xu, Wei-Dong;Wang, Ya-Jie;Wang, Ya-Di;Liu, Chuan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.7249-7254
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    • 2015
  • Background: Previous studies evaluated associations between the CYP1A2 rs762551 polymorphism and bladder cancer risk. However, the results were inconsistent. We therefore performed a meta-analysis of the published case-control studies to assess in detail the association between CYP1A2 rs762551 polymorphism and bladder cancer risk. Materials and Methods: PubMed, Embase and Web of Science were searched to identify relevant studies and the pooled odds ratio (OR) and 95 % confidence interval (95%CI) were calculated. Results: A total of seven articles including 3,013 cases and 2,771 controls were finally included. Overall, a significant association was found between the CYP1A2 rs762551 polymorphism and bladder cancer susceptibility for CC vs AA (OR=0.82, 95% CI=0.69~0.99), but no significant associations were found for the other three models (AC vs AA: OR=0.91, 95% CI=0.81~1.02; the dominant model: OR=0.90, 95% CI=0.80~1.00; the recessive model: OR=0.84, 95% CI =0.72~1.00). In the subgroup analysis by ethnicity, we detected significant associations between the CYP1A2 rs762551 polymorphism and bladder cancer susceptibility for GA vs GG (OR = 0.78, 95% CI =0.64~0.96) and for the recessive model (OR=0.80, 95% CI=0.66~0.96) in Caucasians, but not for Asians. Conclusions: The results from the meta-analysis suggested that the CYP1A2 rs762551 polymorphism is a protective factor for bladder cancer, especially in Caucasians.

A Study on the Determination of Optimal UPFC Location (최적의 UPFC 위치 결정에 관한 연구)

  • Bae, Cherl-O
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.15 no.3
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    • pp.257-262
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    • 2009
  • The unified power flow controller(UPFC) is one of the most effective devices in the FACTS family. This paper concerns about a filtering technique for reducing the computer calculation to determine the optimal location of UPFC in a power system. The sensitivities of the power generation cost for UPFC control parameters are evaluated. This technique requires that only one optimal power flow is run to get UPFC sensitivities for all possible transmission lines. To find out a optimal locating of a single UPFC in power system, an ideal transformer model which consists of a complex turns ratio and a variable shunt admittance was used. In this model, the UPFC control variables do not depend on UPFC input and output currents and voltages. The sensitivity method was tested on a 5-bus system derived from the IEEE 14-bus system and IEEE 14-bus system to establish its effectiveness.

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Driving System of 7-Phase BLDC Motor Speed Control by Fuzzy Controller (Fuzzy 제어기를 이용한 7상 BLDC 전동기 속도제어 구동시스템)

  • Yoon, Yong-Ho
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.11
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    • pp.1663-1668
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    • 2017
  • A BLDC motor with higher number of phases has several advantages, compared to the conventional three-phase BLDC motors. It can reduce the commutation torque ripple and the iron loss without increasing the voltage per phase and increase the reliability and power density. Higher number of phases increase the torque-per-ampere ratio for the same machine volume and output power by widening the electrical conduction period. In this paper, the proposed seven-phase BLDC motor drive system is made into several functional modular blocks, so that it can be easily extended to other ac motor applications: back-EMF block, hysteresis current control block, pwm inverter block, phase current block, and speed/torque control block. Also in a system of BLDC motor drive, the PI controller has been widely used in the speed controller because of the simple implementation. To obtain a good speed response in a general drive system using the PI controller, the high bandwidth of a controller is established. therefore, in this paper, a Fuzzy controller is applied to the 7-phase BLDC motor drive system in order to improve the speed control performance. The Fuzzy controller is compared with a conventional PI controller through the experiment with respect to speed dynamic responses. These experimental results show that the Fuzzy controller of the 7-phase BLDC motor drive system is superior over the conventional PI controller. The algorithm using the Fuzzy controller can improve a comfortable ride in the field of high performance 7-phase BLDC motor drive applications.

Study on the Electrochemical Characteristics of Lithium Ion Doping to Cathode for the Lithium Ion Capacitor (리튬이온 커패시터의 음극도핑 및 전기화학특성 연구)

  • CHOI, SEONGUK;PARK, DONGJUN;HWANG, GABJIN;RYU, CHEOLHWI
    • Transactions of the Korean hydrogen and new energy society
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    • v.26 no.5
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    • pp.416-422
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    • 2015
  • Lithium Ion capacitor (LIC) is a new storage device which combines high power density and high energy density compared to conventional supercapacitors. LIC is capable of storing approximately 5.10 times more energy than conventional EDLCs and also have the benefits of high power and long cycle-life. In this study, LICs are assembled with activated carbon (AC) cathode and pre-doped graphite anode. Cathode material of natural graphite and artificial graphite kinds of MAGE-E3 was selected as the experiment proceeds. Super-P as a conductive agent and PTFE was used as binder, with the graphite: conductive agent: binder of 85: 10: 5 ratio of the negative electrode was prepared. Lithium doping condition of current density of $2mA/cm^2$ to $1mA/cm^2$, and was conducted by varying the doping. Results Analysis of Inductively Coupled Plasma Spectrometer (ICP) was used and a $1mA/cm^2$ current density, $2mA/cm^2$, when more than 1.5% of lithium ions was confirmed that contained. In addition, lithium ion doping to 0.005 V at 10, 20 and $30^{\circ}C$ temperature varying the voltage variation was confirmed, $20^{\circ}C$ cell from the low internal resistance of $4.9{\Omega}$ was confirmed.

Mixed Carbon/Polypyrrole Electrodes Doped with 2-Naphthalenesulfonic Acid for Supercapacitor (2-Naphthalenesulfonic Acid로 도핑된 혼합카본/폴리피롤을 이용한 Supercapacitor용 전극)

  • Jang, In-Young;Kang, An-Soo
    • Korean Chemical Engineering Research
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    • v.43 no.3
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    • pp.425-431
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    • 2005
  • New type of supercapacitor using high surface area activated carbons mixed with high conductivity polypyrrole (Ppy) has been prepared in order to achieve low impedance and high energy density. Mixed carbons of BP-20 and MSP-20 were used as the active electrode material, and polypyrrole doped with 2-naphthalenesulfonic acid (2-NSA) and carbon black (Super P) as conducting agents were added to activated carbons in order to enhance good electric conductivity. Electrodes prepared with the activated electrode materials and the conducting agents were added to a solution of organic binder [P(VdF-co-HFP) / NMP]. The ratio of optimum electrode composition was 78 : 17 : 5 wt.% of (MSP20 : BP-20=1 : 1), (Super P : Ppy=10 : 7) and P(VdF-co-HFP) respectively. The performance of unit cell with addition of 7 wt% Ppy have shown specific capacitance of 28.02 F/g, DC-ESR of $1.34{\Omega}$, AC-ESR of $0.36{\Omega}$, specific energy of 19.87 Wh/kg and specific power of 9.77 kW/kg. With addition of Ppy, quick charge-discharge of unit cell was possible because of low ESR, low charge transfer resistance and quick reaction rate. And good stability up to 500 chargedischarge cycles were retained about 80% of their original capacity. It was concluded that the specific capacitance originated highly from compound phenomena of the pseudocapacitance by oxidation-reduction of polypyrrole and the nonfaradaic capacitance by adsorption-desorption of activated carbons.