• Korean Journal of Optics and Photonics
• /
• v.5 no.2
• /
• pp.311-318
• /
• 1994

We fabricated fiber-optic polarizers utilizing polarization selective mode coupling between the guided mode of a fiber and the surface plasmon mode supported by a thin aluminium film deposited on the polished side of a fiber. AI thin films with various thicknesses were coated onto the 633 nm, 830 nm, 1.3 fJITI single mode fibers. The maximum extinction ratio was higher than 30 dB for most of the samples and the best result was 42 dB at 90 A film thickness, with 1.3 fJITI single mode fiber. The insertion loss ranged from 0.2 dB to 1.5 dB.1.5 dB.

• Bulletin of the Korean Mathematical Society
• /
• v.35 no.2
• /
• pp.319-324
• /
• 1998

The equation AX = BX implies $A^*X\;=\;B^X$ when A and B are normal (Fuglede-Putnam theorem). In this paper, the hypotheses on A and B can be relaxed by usin a Hilbert-Schmidt operator X: Let A be p-quasihyponormal and let $B^*$ be invertible p-quasihyponormal such that AX = XB for a Hilbert-Schmidt operator X and $|||A^*|^{1-p}||{\cdot}|||B^{-1}|^{1-p}||\;{\leq}\;1$.Then $A^*X\;=\;XB^*$.

• BMB Reports
• /
• v.49 no.4
• /
• pp.238-243
• /
• 2016

The efficacy of anticancer drugs depends on a variety of signaling pathways, which can be positively or negatively regulated. In this study, we show that SETDB1 HMTase is down-regulated at the transcriptional level by several anticancer drugs, due to its inherent instability. Using RNA sequence analysis, we identified FosB as being regulated by SETDB1 during anticancer drug therapy. FosB expression was increased by treatment with doxorubicin, taxol and siSETDB1. Moreover, FosB was associated with an increased rate of proliferation. Combinatory transfection of siFosB and siSETDB1 was slightly increased compared to transfection of siFosB. Furthermore, FosB was regulated by multiple kinase pathways. ChIP analysis showed that SETDB1 and H3K9me3 interact with a specific region of the FosB promoter. These results suggest that SETDB1-mediated FosB expression is a common molecular phenomenon, and might be a novel pathway responsible for the increase in cell proliferation that frequently occurs during anticancer drug therapy.

• Journal of Magnetics
• /
• v.1 no.1
• /
• pp.31-36
• /
• 1996

An externally applied magnetic field during heat treating the $Nd_2Fe_{14}B/Fe_3B$ based spring magnet was found to enhance the exchange coupling between the hard and soft magnetic grains. More than 30% increase in $M_r/M_s$ values for melt-spun $Nd_2Fe_{73.5}Co_3$$(Hf_{1-x}Ga_x)B_{18.5}$ (x=0, 0.5, 1) alloys was resulted from a uniform distribution of $Fe_3B, \alpha-Fe$ and $Nd_2Fe_{14}B$ phases, and also from a reduced grain size of those phases by 20%. The externally applied magnetic field induced a uniform distribution of fine grains. A study of Mossbauer effect also report that the enhancement of total magnetization of nanocomposite $Nd_2Fe_{14}B/Fe_3B$ alloys is attributed to an increased formation of $Fe_3$B after magnetic annealing.

• Bulletin of the Korean Chemical Society
• /
• v.25 no.12
• /
• pp.1845-1849
• /
• 2004

Apolipoprotein B-100 (Apo-B100) is a major protein component for low density lipoproteins (LDL). A number of mimetic peptides of Apo-B100 were screened from the phase-displayed random peptide library by utilizing monoclonal antibody (B9). Mimetic peptide for B9 epitope against apo B-100 was CRNVPPIFNDVYWIAF (pB1). From the BLAST search, the mimetic peptide pB1 had 40% homology with apo B-100. As a result of the structural determination of this mimotope using homo/hetero nuclear 2D-NMR techniques and NMR-based distance geometry (DG)/molecular dynamic (MD) computations, DG structure had low penalty value of 0.3-0.6 ${\AA}^2$ and the total RMSD was 0.5-1.5 ${\AA}. Moreover, pB1 structure included a weak $3_{10}$-helix from $Ile^7$,/TEX> to $Trp^{13}$.

• Development and Reproduction
• /
• v.15 no.3
• /
• pp.223-230
• /
• 2011

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants derived from incomplete combustion of carbons and crude oil. In this study, we investigated the effects of benzo[a]pyrene (B[a]P), a representative PAHs on in vitro sex steroid hormone production and germinal vesicle breakdown (GVBD) using isolated oocytes of longchin goby (Chasmichthys dolichognathus) and chameleon goby (Tridentiger trigonocephalus). Oocytes in diameters of 0.8-0.9 (end vitellogenic stage) and 0.9-1.0 mm (germinal vesicle migratory stage) from longchin goby and 0.5 mm (fully vitellogenic stage) from chameleon goby were used. In GVBD assay, B[a]P at 10 nM stimulated GVBD in the oocytes of 0.8-0.9 mm from longchin goby. B[a]P at 1 nM stimulated GVBD in the oocytes with diameter 0.5 mm from chameleon goby. In steroid production from oocytes of longchin goby, B[a]P at 100 nM decreased testosterone (T) production, B[a]P at 1,000 nM increased estraiol-17 (J (E2) production and 10 and 100 nM increased $17,20{\beta}$-dihydroxy-4-pregnen-3-one ($17{\alpha}20{\beta}P$) production in the oocytes with diameter 0.8-0.9 mm. B[a]P at 1,000 nM increased E2 production, 100 and 1,000 nM increased $17{\alpha}20{\beta}P$ production in the oocytes with diameter 0.9-1.0 mm. In steroid production of oocytes from chameleon goby, B[a]P at 1,000 nM increased $E_2$ production. B[a]P at 10 nM increased $17{\alpha}20{\beta}P$ production. In the ratio of $E_2$ to T ($E_2$/T), B[a]P at 100 and 1,000 nM increased $E_2$/T in the oocytes of longchin goby. B[a]P at 100 nM also increased $E_2$/T in the oocytes of chameleon goby. Taken together, these results suggest that B[a]P have not only weak estrogenic effects but progestogenic effects on oocyte maturation.

• Biomedical Science Letters
• /
• v.21 no.4
• /
• pp.218-226
• /
• 2015

The present study investigated the mechanisms of licochalcone B (LicB)-mediated inhibition of the inflammatory response in murine macrophages. RAW264.7 murine macrophages were cultured in the absence or presence of lipopolysacharide (LPS) with LicB. LicB suppressed the generation of nitric oxide and the pro-inflammatory cytokines interleukin (IL)-$1{\beta}$, IL-6 and tumor necrosis factor-${\alpha}$. LicB also inhibited the expression of mRNA for inducible nitric oxide synthase and pro-inflammatory cytokines induced by LPS. Moreover, LicB inhibited nuclear factor-${\kappa}B$ (NF-${\kappa}B$) and activator protein-1 translocation into the nucleus in a dose-dependent manner. Thus, LicB mainly exerts its anti-inflammatory effects by inhibiting the LPS-induced NF-${\kappa}B$ and activator protein-1 signaling pathways in macrophages, which subsequently diminishes the expression and release of various inflammatory mediators. LicB shows promise as a therapeutic agent in inflammatory diseases.

• Journal of Microbiology and Biotechnology
• /
• v.12 no.4
• /
• pp.679-682
• /
• 2002

The alkaloids, piperlongumine, piperine, pipernonaline, and piperoctadecalidine, isolated from Piper longum L., were found to inhibit the biosynthesis of aflatoxin $B_1$ (AF$B_1$) in Aspergillus flavus WRRC 3-90-42-12. Piperlongumine was the most active among the compounds tested, with a 96% inhibition of AF$B_1$biosynthesis at 0.2% (w/v) supplement in a potato dextrose agar (PDA) medium. The three other piperidine alkaloids, pipeline, pipernonaline, and piperoctadecalidine, also inhibited the biosynthesis of AF$B_1$. Of these three alkaloids, piperoctadecalidine exhibited a potent inhibitory activity with a 100% inhibition of AF$B_1$ production at 0.7% (w/v) supplement in a PDA medium. Therefore, piperlongumine and piperoctadecalidine could be used as antiaflatoxigenic agents in agricultural industries. To determine the antiaflatoxigenic mode of action of piperlongumine, further studies are needed.

• Korean Management Science Review
• /
• v.11 no.1
• /
• pp.129-144
• /
• 1994

B-ISDN(Broadband Integrated Services Digital Network)which is defined as a service or system requiring transmission channels capable of supporting rates above 1.5 Mbps has emerged as a new future telecommunication infrastructure. B-ISDN can integrate a wide range of services and the success of B-ISDN is crucially dependent on the development of user-needing application services. The purpose of this study is the conceptual development of B-ISDN application services. We survey on the kinds of B-ISDN service, classify application areas by user groups, and develop B-ISDN application services. Finally we categorize B-ISDN application services by their application areas and necessary services.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.28 no.1A
• /
• pp.25-33
• /
• 2003

We derive the outage probabilities for the Erlang capacity and link margin based on handoffs in the reverse link of a CDMA system of 14.4 kbps/1.9 GHz band, calculate them with the same parameters, and then with the maximum realizable Erlang capacity analyze newly the cell coverage in different areas by the COST-231 model If it decreases from 5 % to 2 % in case of $E_b/N_0$=5 dB under a soft handoff, the result shows a very reliable link with additional increment of 0.88 dB in the margin and a high quality of service within the coverage decrease of 0.12 km, 0.25 km, and 1 km in a city, suburban, and open areas respectively on the decrease of 2 Erlang in the capacity. When the $E_b/N_0$ decreases from 7 dB to 5 dB within the outage probability of 5 %, it shows the increase of 9 Erlang and of 0.2 km in a city on the same margin of 2.8 dB. Then, comparing it with a single cell, it shows the decrease of more than 10 Erlang in the capacity, but the enlargement of 0.17 km, 0.3 km, and 1 km in them on the margin decrease of 1.31 dB, also, with a hard handoff, the soft handoff gain of the increase of 10 Erlang and of 0.22 km, 0.5 km, and 2 km on the decrease of 2.16 dB.