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성대 결절 및 폴립 병변 판별 예측모형에 대한 연구 (A Study of the Lesional Grade Discrimination Model for Vocal Fold Nodules and Polyps)

  • 박수정;심현섭;정성민;김한수;박애경
    • 대한후두음성언어의학회지
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    • 제15권2호
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    • pp.112-117
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    • 2004
  • Background and Objectives : This study is purposed to investigate the statistically significant discrimination model for predicting vocal fold nodule and polyp's lesional grade, with patients' background data and objective voice evaluation parameters. Materials and Method : The retrospective research was carried out at the Ewha Womans University Hospital. 122 patients' voice examination data had been selected, and lesion screening (Grade I, II, and III) was conducted by 2 ENT specialists, with each patient's vocal fold pictures achieved during the laryngoscopy examination. Results : The Lesional Grade Discrimination Model with which the lesional grade of vocal fold nodules and polyps could be predicted was derived by the ordinal logistic regression analysis (using SPSS 10.0). With this model the lesional grades of 73 out of 122 patients(59.8%) were correctly predicted to their formerly screened ones. Conclusion : This model applied the multivariate approach, which statistically combined these currently used parameters, Jitter, Shimmer, MFR, MPT, and patient's background data such as gender and dysphonia period. It might explain the status of benign lesion of vocal folds, and furthermore expect the physiological function of vocal folds.

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Association between the Metabolic Syndrome and High Tumor Grade and Stage of Primary Urothelial Cell Carcinoma of the Bladder

  • Ozbek, Emin;Otunctemur, Alper;Dursun, Murat;Koklu, Ismail;Sahin, Suleyman;Besiroglu, Huseyin;Erkoc, Mustafa;Danis, Eyyup;Bozkurt, Muammer
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권3호
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    • pp.1447-1451
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    • 2014
  • Purpose: To compare histopathologic findings of patients who underwent transurethral resection of a bladder tumor (TUR-B) between groups with and without the metabolic syndrome. Materials and Methods: We retrospectively analyzed data of 535 patients who underwent TUR-B in our department between October 2005 and March 2011. All patients had primary urethelial cell carcinoma (UCB). Histologic stage, grade, the presence of hypertension, diabetes mellitus, body mass index (BMI), waist circumference, HDL and trigliseride levels were evaluated. The TNM classification was used, with Ta tumor accepted as lower stage and T1 and T2 tumors as higher stage bladder cancers. Also, the pathological grading adopted by the 2004 World Health Organization grading system were applied. Non-invasive papillary urothelial neoplasms of low malignant potential were regarded as low grade. Results: Among the total of 509 patients analyzed in our study, there were 439 males (86.2%) and 70 females (13.8%). Metabolic syndrome was significantly associated with high histologic grade, and high pathologic stage (p<0.001). Conclusions: The patients with metabolic syndrome were found to have statistically significant higher T stage and grade of bladder cancer. Further studies with more patients are needed to confirm our study.

한우 등심의 위치별 조지방 함량 및 근내지방도 비교 (Comparison of crude fat content and intramuscular fat score at different position of loin from Hanwoo)

  • 이철우;이한현;백준오;박준규;정사무엘;조철훈
    • 농업과학연구
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    • 제42권1호
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    • pp.47-51
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    • 2015
  • This study was conducted to make certain that the intramuscular fat score at 13th rib could represent the fat content of whole loin from Hanwoo in Korea beef grading system. A total 42 loins from 23 carcasses of grade $1^{{+}{+}}$, 16 carcasses of grade $1^+$, and 3 carcasses of grade 1 of Hanwoo were used for this study. The crude fat content and intramuscular fat score at the $1^{st}$, $6^{th}$, and $13^{th}$ rib, and the last lumbar position of loin were measured. The crude fat content was the highest at the $6^{th}$ rib of loin from the carcasses of grade $1^{{+}{+}}$ and $1^+$ (p<0.05). There were no significant difference of the intramuscular fat scores measured by image analysis and beef marbling score (BMS) between the 6th and $13^{th}$ rib of loin from the carcasses of $1^{{+}{+}}$ and $1^+$ and that were significantly higher than intramuscular fat scores at the $1^{st}$ rib and the last lumbar position of the loin. From the results, we conclude that the intramuscular fat score at the $13^{th}$ rib can represent the fat content of loin when meat graders decide the grade of Hanwoo carcass.

취학 전 미디어 노출과 어머니의 우울이 초등학교 1학년의 학교 적응에 미치는 종단적 영향: 주의집중문제의 매개효과 (Longitudinal Effects of Preschool Children's Media Exposure and Maternal Depression on School Adjustment during First Grade: Mediating Effect of Attention Problem)

  • 서보림;한희수;김태련;조진실;강민주
    • Human Ecology Research
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    • 제58권2호
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    • pp.267-278
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    • 2020
  • This study examined the longitudinal effect of preschool children's media exposure and maternal depression on first-grade children's school adjustment and the mediating effect of attention problem. Longitudinal data from the Panel Study of Korean Children (PSKC) collected by the Korea Institute of Child Care and Education (KICCE) was used to examine this hypothetical model. The subjects of the study included 2,150 children (1,091 boys and 1,059 girls) and their mothers across 2013 (5 yrs.) through 2015 (7 yrs.). The Structural Equation Model (SEM) was estimated using SPSS 25.0 and Amos 25. The results of this study were as follows. First, higher level of preschool children's media exposure and maternal depression were related to higher attention problems after a year and lower level of children's school adjustment during first-grade. Second, preschool children's media exposure and maternal depression had an indirect effect on first-grade children's school adjustment via attention problem. The results of this study will provide supporting evidence to many educators and parents for the implementation of effective practices for first-grade children to enhance their school adjustment. Furthermore, this study emphasizes the importance of maternal psychological wellbeing and the risk of indiscriminate media exposure during early childhood on first-grade's school adjustment.

저변성퇴적암 사면에서 지질특성이 차별풍화에 미치는 영향 (Effect of geological characteristics on differential weathering of low-graded metasedimentary rock slopes)

  • 정해근;서용석;임명혁
    • 한국터널지하공간학회 논문집
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    • 제15권4호
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    • pp.375-385
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    • 2013
  • 본 논문에서는 천매암을 중심으로 저변성퇴적암류에 속하는 암석을 대상으로 암석학적 특징과 풍화도의 상관성에 대하여 분석하였다. 현장 지질조사를 통하여 암석의 풍화도를 결정하였고, 구성암석의 강도 값을 추정하기 위하여 슈미트해머 테스트를 실시하였다. 9개 시료의 현미경 박편 관찰을 통하여 주구성광물의 부피비와 엽리의 간격을 측정하였다. 암석시료의 현미경 분석 결과에 의하면 풍화도가 낮을수록 풍화에 강한 석영성분이 많고, 풍화도가 높을수록 풍화에 약한 운모성분이 많은 것으로 나타났다. 또한 엽리 간격이 좁을수록 강도는 낮고 풍화도는 높은 것으로 나타났다.

Immunohistochemical Assessment of E-cadherin and β-catenin in the Histological Differentiations of Oral Squamous Cell Carcinoma

  • Zaid, Khaled Waleed
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권20호
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    • pp.8847-8853
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    • 2014
  • The aim of this study was to establish the expression and localization of E-cadherin and ${\beta}$-catenin in oral squamous cell carcinomas (OSCC) so that we could correlate the findings with prognostic-relevant histopathological variables. E-cadherin and ${\beta}$-catenin expression in normal oral epithelia and in oral squamous cell carcinomas was examined immunohistochemically, and associations with histopathological differentiation and prognosis were then analyzed in 33 patients who had been operated on for OSCC. E-cadherin expression was found in (82%) of the squamous cells of well differentiated OSCC, (61%) of moderately differentiated and (39%) of poorly differentiated. E-cadherin expression was significantly associated with histological grade (p=0.000). No nuclear staining was detected. In (19.5%) of the cells E-cadherin localized in the cytoplasm, with no correlation to the histological grade (p=0.106). ${\beta}$-Catenin expression was found in 87% of the squamous cells of well differentiated OSCC, 67% of moderately differentiated and 43% of poorly differentiated, the expression was significantly associated with histological grade (p=0.000). the nuclear ${\beta}$-Catenin expression appeared in 3.3% of the cells and it was correlated to the histological grade (p=0.000). In (23.5%) of the cells ${\beta}$-Catenin localized in the cytoplasm, with correlation to the histological grade (p=0.002). According to this study the expression of ${\beta}$-catenin and E-cadherin were independent prognostic factors for histological grade. E-cadherin was closely linked to ${\beta}$-catenin expression in OSCC (p=0.000) and to tumor differentiation. That reflects a structural association and the role of both in tumor progression.

서울 지역 일부 아동 및 청소년의 성장발달 및 식생활 비교 연구: 식품 및 영양소 섭취 실태(II) (The Physical Development and Dietary Intake for Korean Children and Adolescents: Food and Nutrient Intake)

  • 송윤주;정효지;김영남;백희영
    • Journal of Nutrition and Health
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    • 제39권1호
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    • pp.50-57
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    • 2006
  • The aim of this study was to evaluate the food and nutrient intakes in 5th to 8th grade school boys and girls. A total of 1,333 students were recruited from 1 elementary and 1 middle school, both located in Seoul. The data on food and nutrients intake were collected by 3-day food record. The food intake was calculated as the percentage of total energy intake according to 21 food subgroups. The consumption of noodles, and meat's products (including ham and sausage) groups were higher in 7th and 8th grade than 5th and 6th grade. On the other hand consumption of vegetables and milk & its products groups were lower in 7th and 8th grade. As results, calcium, riboflavin, and vitamin C intakes were lower in 7th and 8th grade students. Dietary patterns by cluster analysis resulted in $77\%$ of subjects with traditional pattern based rice and kimchi, and $23\%$ with modified pattern. All students regardless of grades showed high fat intake, above 20 percent energy intake from fat, and high cholesterol intakes. In conclusion, there was significant difference between 5th and 6th grade primary school students and 7th and 8th junior school students regarding food and nutrient intakes; It should be necessary to provide proper nutrient education and monitoring in order to establish good dietary profile.

도축검사 후 지방성 병변과 축산물 품질 연관성 조사 (A survey of the relation between fatty lesions after slaughter inspection results and cattle carcasses quality grades in Korea)

  • 성창민;지태경;최종욱;박다해;박대희;김현중;김용환;김은선
    • 한국동물위생학회지
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    • 제36권2호
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    • pp.121-125
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    • 2013
  • The survey was conducted to investigate the relation between slaughter inspection results and the quality of cattle carcasses by inquiring animal products grading service results of Korea Institute for Animal Products Quality Evaluation (KAPE) about partial-disposed cattle carcasses after dismantling inspection. Of the 13,586 slaughtered cattle, 1,343 (9.9%) cattle heads were partially disposed from January to August, 2012 at slaughterhouses in Gwangju area, Korea. Of the 1,343 partial disposed cattle, 613 (45.6%) cattle carcasses were graded into above "Grade 1". Among partially disposed 1,171 Hanwoo heads, 613 (52.3%) cattle carcasses were graded into above "Grade 1". However, none of dairy and beef cattle carcasses were graded into above "Grade 1" out of 163 and 9 partial disposals, respectively. Of the 221 partial disposals by enteric fat necrosis, 139 carcasses were graded into above "Grade 1", and the ratio; 62.9% (P=0.001), was higher than that (50.3%) of total cattle carcass grade which is above "Grade 1". From these results, it is suggested that quality of cattle carcasses which is mainly determined by marbling might be related to the fatty lesions such as fatty liver and enteric fat necrosis.

초등학교 1~2학년 수학 교과서 어휘의 등급 및 유형별 분석 (An Analysis of Vocabulary Rating and Types in Elementary Mathematics Textbooks for Grade 1-2)

  • 박미미;이은정
    • 한국수학교육학회지시리즈C:초등수학교육
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    • 제25권4호
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    • pp.361-375
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    • 2022
  • 이 연구에서는 2015 개정 교육과정에 따른 초등학교 1~2학년 수학 교과서 어휘를 등급 및 유형에 따라 분석하였다. 어휘 유형은 학습 도구어, 수학 교과 특수 개념어, 수학 교과 일반 개념어로 구분하여 분석하였다. 어휘 등급별 분석 결과, 1~2학년 수학 교과서에서는 1등급과 2등급 어휘가 대부분을 차지하고 있었다. 어휘 유형별 분석 결과, 학습 도구어 중 일부 어휘가 3등급 어휘로 나타났으며, 수학 교과 특수 개념어의 경우 미등록어이거나 1등급 어휘인 경우들이 많았다. 수학 교과 일반 개념어는 2학년 교과서에서의 빈도수가 1학년 교과서에 비해 크게 증가하였다. 이러한 결과를 기반으로 수학 교과서 어휘 지도를 위한 시사점을 제시하였다.

Effect of Tart Cherry Juice Consumption on Body Composition and Anthropometric Measures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Mohammad Reza Amini;Nastaran Payandeh;Fatemeh Sheikhhossein;Hossein Shahinfar;Sanaz Pourreza;Azita Hekmatdoost
    • Clinical Nutrition Research
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    • 제12권1호
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    • pp.65-76
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    • 2023
  • The present systematic review and meta-analysis were accomplished to understand the effects of tart cherry juice consumption on body composition and anthropometric measures. Five databases were searched using relevant keywords from inception to January 2022. All clinical trials investigating the effect of tart cherry juice consumption on body weight (BW), body mass index (BMI), waist circumference (WC), fat mass (FM), fat-free mass (FFM), and percentage body fat (PBF) were included. Out of 441 citations, 6 trials that enrolled 126 subjects were included. Tart cherry juice consumption significantly did not reduce BW (weighted mean difference [WMD], -0.4 kg; 95% confidence interval [CI], -3.25 to 2.46; p = 0.789; GRADE = low), BMI (WMD, -0.07 kg/m2; 95% CI, -0.89 to 0.74; p = 0.857; GRADE = low), FM (WMD, 0.21 kg; 95% CI, -1.83 to 2.25; p = 0.837; GRADE = low), FFM (WMD, -0.12 kg; 95% CI, -2.47 to 2.27; p = 0.919; GRADE = low), WC (WMD, 1.69 cm; 95% CI, -1.88 to 5.27; p = 0.353; GRADE = low), and PBF (WMD, 0.18%; 95% CI, -1.81 to -2.17; p = 0.858; GRADE = low). Overall, these data suggest that tart cherry juice consumption has no significant effect on BW, BMI, FM, FFM, WC, and PBF.