• 제목/요약/키워드: A-KRS

검색결과 60건 처리시간 0.023초

KAERI A-KRS 골드심 성능평가 모델 비교 검증 연구 (A-KRS GoldSim Model Verification: A Comparison Study of Performance Assessment Model)

  • 이연명;정종태
    • 방사성폐기물학회지
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    • 제11권2호
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    • pp.103-114
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    • 2013
  • 한국원자력연구원에서는 사용후핵연료를 직접 처분하는 대신 이를 처리하여 발생하는 방사성 폐기물을 심지층에 직접 처분하는 방식의 A-KRS 개념의 방사성폐기물 처분 시스템을 개발해 오고 있다. 이러한 A-KRS 개념에 대한 장기적 안전성 및 처분 시스템 성능 평가를 위한 모델을 GoldSim을 이용 개발하고 이를 지속적으로 수정 보완하고 개선해 오고 있다. KAERI에서 개발된 A-KRS 모델의 신뢰도를 증진 시키기 위하여 유사하게 개발된 다른 모델과의 벤치마킹을 통한 비교 연구의 결과를 제시하였다. A-KRS모델을 미국 NRC에서 SwRI 연구소의 협력을 통하여 개발하여 처분 시스템 성능평가에 활용한 SOAR와 비교하고 병행하여 스웨덴의 SKB에서 최근 수행한 SR-SiTE 안전성 평가를 통하여 KBS-3 개념의 처분 시스템 내 전단 응력에 따른 용기의 파손에 따른 유출 계산 결과와도 비교 검토하여, 전반적으로 상호 잘 일치하는 결과를 얻어 내었다. 보다 개선된 GoldSim으로의 모델의 이행의 필요성은 있으나 A-KRS 모델이 GoldSim을 통해 잘 이행되어 처분 시스템 안전성 평가에 적합한 것으로 나타났다.

Lysyl-tRNA Synthetase Inhibits Various Shear Stress-stimulated Signaling Pathways in Endothelial Cells

  • Park, Heon-Yong
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 2008년도 Proceedings of the Convention
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    • pp.103-115
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    • 2008
  • Hemodynamic shear stress, the dragging force generated by blood flow, is known as an anti-atherogenic factor. We tested whether lysyl-tRNA synthetase (KRS) will be utilized as an agent controlling shear-sensing systems. KRS was previously known to be secreted as a pro-inflammatory agent. Here we found that KRS inhibited various shear-stimulated signaling pathways. We further found that KRS binds to detergent-resistant membrane (DRM), indicating that KRS binding molecules exist in DRM, specialized regions of the plasma membrane. DRM plays important roles in a variety of cellular processes and consists of gangliosides, signaling molecules and cytoskeletons. We then determined that KRS was colocalized with integrins ${\alpha}4$, ${\alpha}5$ and $av{\beta}3$. In addition, KRS was shown to be associated with sialic acid, existing at the end of gangliosides. Interestingly, the adherent effect of KRS was inhibited by pretreatment with sialic acid. Moreover, treatment of endothelial cells with neuraminidase appeared to inhibit both the KRS adhesion to endothelial cells and shear-stimulated signaling. In conclusion, KRS is likely to be utilized as a vascular regulator.

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한국철도표준규격 국제규격 부합화 : 자동연결기 (The Conformity of Korean Railway Standards with International Standards : Automatic Coupler)

  • 김정국;이창영;서정원;권성태
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2009년도 춘계학술대회 논문집
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    • pp.213-218
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    • 2009
  • The Korean railway standards (KRS), formerly managed by Korea Railroad (Korail), have been managed by the Korean Ministry of Land, Transport and Maritime Affairs (ML TM). According to Korean railway safety law and its ordinances, which were established for the guarantee of railway safety, the management of KRS including enactment and revision of technical standards for railway vehicle and components, was committed to Korea Railroad Research Institute (KRRI). Currently, a total of 195 standards has been managed from the various railway applications including track, electrical, and vehicle areas. Moreover, according to the guideline on the management of KRS, the conformity of KRS with international standards is encouraged for the enlargement of international trade. In this investigation, a brief management activity of KRS and the recent activities on conformity of KRS with AAR standards on automatic coupler will be introduced.

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Antifungal and Plant Growth Promotion Activities of Recombinant Defensin Proteins from the Seed of Korean Radish (Raphanus sativus L.)

  • Hwang, Cher-Won
    • 한국환경농학회지
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    • 제28권4호
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    • pp.435-441
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    • 2009
  • In the present study, we analyzed the defensin protein deduced from Korean radish (Raphanus sativus L.) seeds.To express the genes in E. coli, we constructed a recombinant expression vector with a defensin gene, named rKRs-AFP gene isolated from Korean radish seeds. Over expressed rKRs-AFP proteins was separated by SDS-PAGE to determine the purity, and protein concentration was determined by the Bradford method. Antifungal activity was assessed by disk assay method against the tested fungi. As a result, when 500 mL of cell culture were disrupted by sonicator, 32.5 mg total proteins were obtained. The purified protein showed a single band on SDS-PAGE with estimated molecular weight about 6 KDa, consistent with the molecular mass calculated from the deduced amino acid sequence. The purified rKRs-AFP protein showed remarkable antifungal activities against several fungi including Aspergillus niger, Botrytis cinerea causing the gray mold disease, and Candida albicans. In field tests using the purified rKRs-AFP protein, the protein showed the reducing activity of disease spot and the mitigating effect of spreading of disease like agrichemicals. The immuno-assay of rKRs-AFP protein showed that the purified protein entirely accumulated at B. cinerea cytoplasm through the hyphal septa shown by fluorescence imaging. There was no fluorescence inside the cell, when the hypha was incubated without the protein. These all results indicate that the recombinant rKRs-AFP proteins can be utilized as a potential antifungal drug to control harmful plant fungal pathogens.

SAT#1 (Preliminary Integration) Test Results of KASS System

  • Jeong, Hwanho;Jang, HyunJin;Kim, Koontack;Lee, Jaeeun;Lee, ByungSeok
    • Journal of Positioning, Navigation, and Timing
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    • 제10권2호
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    • pp.145-151
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    • 2021
  • According to the Korea Augmentation Satellite System (KASS) system milestone, Site Acceptance Test (SAT) has three steps test until the end of the project. SAT#1 is the first time of SAT steps and verify the KASS Reference Station (KRS) and Sub System (S/S) for the monitoring and controllable. After the equipment and software were installed at the Mission Control Center (MCC) with Central Monitoring and Control Simulator (CMS) for the SAT#1, the 1:1 test was progressed when the KRS and S/S are ready to test. SAT#1 has a 10 steps test case and it was progressed each KRS sites. The test was finished throughout the real-time monitoring and the data collection including the data analysis all of the 7 KRS sites. Finally SAT#1 was completed on December 2020 with successfully.

Multipath Error Analysis and Scenario Generation for Verifying KRS Environment

  • Cho, Sunglyong;Choi, Heonho;Lee, Byungseok;Nam, Giwook
    • Journal of Positioning, Navigation, and Timing
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    • 제9권2호
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    • pp.71-77
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    • 2020
  • KRS which is subsystem of Korea Augmentation Satellite System (KASS) performs a role of collecting and monitoring GPS signals. In order to generate the accurate correction message, the site which meets the requirements should be selected and verification to meet each requirement should be accompanied. When the sites are selected, the environmental considerations are EMI, clear horizon (CH) and multipath. Of these, EMI and CH can be checked for satisfaction by instrumentation, but multipath error is difficult to predict. Therefore, multipath error analysis for the installation position of actual antenna at each KRS site should be preceded, and multipath scenario should be generated for each location to analyze the effects of the resulting system performance. In this paper, based on satellite signals collected from each KRS sites, the method for analyzing multipath error in each KRS sites is described, and the multipath error is analyzed. Also to perform an analysis of the effects on system performance due to multipath error, multipath error modeling is performed for the generation of simulation scenarios.

KURT 부지 조건에서 A-KRS 입지 영역 도출 (Potential repository domain for A-KRS at KURT facility site)

  • 김경수;박경우;김건영;최희주
    • 방사성폐기물학회지
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    • 제10권3호
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    • pp.151-159
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    • 2012
  • 선진핵주기 고준위폐기물 처분시스템의 개념설계를 위하여 가상의 처분장 부지인 KURT 시설 부지의 지질조건에서 A-KRS의 입지 후보영역을 선정하였다. 부지의 모암은 한반도에 폭넓게 분포하는 중생대 화강암을 대표하는 것으로 열수변질작용을 받은 흔적이 있으며, 지표수와 지하수계는 일차적으로 지형의 영향을 받아 부지에서 남동진하여 금강으로 배출된다. 부지 내에서 확인된 단열대는 2 등급 규모로서 N-S와 E-W 주향으로 우세하게 분포한다. A-KRS 입지 후보영역을 제안하기 위하여 부지 내에서 공간적으로 -500 m 심도까지 발달되는 것으로 예상되는 단열대를 교차하지 않고 동시에 단열대로부터 50 m 이상의 충분한 이격거리를 갖는 조건에서 처분장 규모의 영역을 확보할 수 있는지를 분석하였다. 분석 결과, 본 부지의 중앙부에 우세하게 분포하는 남북 방향의 주향을 갖는 단열대의 서쪽 영역의 -200 m 이하 심도에서 충분한 영역을 확보할 수 있는 것으로 확인되었다. 단열대의 분포 특성을 감안할 때 부지의 좌하단 영역이 지질학적, 수리지질학적 측면에서 A-KRS 입지 영역으로 가장 양호한 것으로 판단된다.

Scoping Calculations on Criticality and Shielding of the Improved KAERI Reference Disposal System for SNFs (KRS+)

  • Kim, In-Young;Cho, Dong-Keun;Lee, Jongyoul;Choi, Heui-Joo
    • 방사성폐기물학회지
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    • 제18권spc호
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    • pp.37-50
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    • 2020
  • In this paper, an overview of the scoping calculation results is provided with respect to criticality and radiation shielding of two KBS-3V type PWR SNF disposal systems and one NWMO-type CANDU SNF disposal system of the improved KAERI reference disposal system for SNFs (KRS+). The results confirmed that the calculated effective multiplication factors (keff) of each disposal system comply with the design criteria (< 0.95). Based on a sensitivity study, the bounding conditions for criticality assumed a flooded container, actinide-only fuel composition, and a decay time of tens of thousands of years. The necessity of mixed loading for some PWR SNFs with high enrichment and low discharge burnup was identified from the evaluated preliminary possible loading area. Furthermore, the absorbed dose rate in the bentonite region was confirmed to be considerably lower than the design criterion (< 1 Gy·hr-1). Entire PWR SNFs with various enrichment and discharge burnup can be deposited in the KRS+ system without any shielding issues. The container thickness applied to the current KRS+ design was clarified as sufficient considering the minimum thickness of the container to satisfy the shielding criterion. In conclusion, the current KRS+ design is suitable in terms of nuclear criticality and radiation shielding.

A-KRS 처분 시스템 결정론적 안전성 평가 (A Deterministic Safety Assessment of a Pyro-processed Waste Repository)

  • 이연명;정종태;최종원
    • 방사성폐기물학회지
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    • 제10권3호
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    • pp.171-188
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    • 2012
  • 파이로 처리 방사성 폐기물 처분 시스템 A-KRS에 대한 결정론적, 확률론적 안전성 평가가 가능하도록 골드심 프로그램을 개발하였다. 처분장에서 핵종이 유출되어 다양한 처분 시스템 내 매질을 이동하는 것에 관련된 주요 시나리오를 도출하기 위하여 처분 시스템을 구성하는 각 요소 별로, 그리고 처분 시스템 내 핵종의 이동에 관여하는 FEP을 인지 선별하여 수학적 모델을 개발하고 이를 골드심 템플릿 프로그램으로 개발하였다. 이 프로그램을 이용하여 폐쇄후 방사선적 안전성 평가를 결정론적으로 수행하여 5개의 정상 및 비정상 시나리오를 평가하여 그 결과를 상호 비교하였다.

Geodetic Survey Campaigns and Maintenance Plan for KASS Reference Station Antenna Coordinates

  • Hwanho, Jeong;Hyunjin, Jang;Youngsun, Yun;ByungSeok, Lee
    • Journal of Positioning, Navigation, and Timing
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    • 제12권1호
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    • pp.83-89
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    • 2023
  • The Korea Augmentation Satellite System (KASS) system is a Satellite Based Augmentation System (SBAS) under development to provide APV-I SBAS service in the Republic of Korea. The KASS ground segment generates correction and integrity information for GPS measurements of KASS users using the accurate positions of KASS Reference Station (KRS) antenna phase centers. For this reason, the accuracy of KRS reference points through geodetic survey campaigns is one of the important factors for providing the KASS service in compliance with the required navigation performance. In order to obtain accurate positions, two geodetic survey campaigns were performed at several reference points, such as Mark, Center of Mast at Ground Level (CMGL), and Center of Hole in Top Plate (CHTP), of each KRS site using three different survey methods, the Virtual Reference Station (VRS), Flächen Korrektur Parameter (FKP), and raw data post-processing methods. By comparing and analyzing the results, the computed coordinates of the reference points were verified and Antenna Phase Center (APC) positions were calculated using KRS Antenna Reference Point (ARP) data, and the first KASS Site Acceptance Test (SAT#1) was performed successfully using the verified APC coordinates. After the first site survey activities, the KASS operators should maintain the coordinates with the required performance such that the overall KASS navigation performance commitment is guaranteed during the lifetime of 15 years. Therefore, the maintenance plan for the KRS antenna coordinates should be developed before the commissioning of KASS operation planned after 2023. Therefore, this paper presents a geodetic survey method selected for the maintenance activities and provides the rationale for using this method.