• Title/Summary/Keyword: A/W

검색결과 33,299건 처리시간 0.058초

Aspergillus Terreus에 의한 이타콘산 생산을 위한 최적배양조건에 관한 연구 (Studies on the Optimal Culture Conditions for Itaconic Acid Production by Aspergilus Terreus)

  • 박승원;김승욱
    • KSBB Journal
    • /
    • 제9권4호
    • /
    • pp.436-442
    • /
    • 1994
  • Aspergillus terreus NRRL 1960에 의한 이다콘산의 생산에 관해 연구하였다. pH, 접종량, 배지조성 등의 최적조건을 확립하였다. 이타콘산의 최대생산 량은 37°C, pH 2.5의 조건에셔, 5% (w/v) glu­c cose, 0.5 % (w/v) $NH_4Cl$, 0.2 % (w/v) yeast ex­tract, 0.1 % (w/v) $MgSO_4$, 0.2 % (w/v) NaCI을 포함하는 배지에서 7일만에 $19.18g/\ell$를 얻을 수 있었다. 종균배양 배지로서 2 % malt extract가 적합하였다. 교반식 반응기에서 유리균체에 의한 이타콘 산의 회분식 생산은 플라스크 배양에 비해 비효율적 이었다.

  • PDF

유제화에 의한 경구용 항암제인 테가푸르의 장관 임파수송 (Mesenteric Lymphatic Delivery of Oral Anticancer Tegafur by Emulsion Formulations)

  • 이용복;남권호;장우익;오인준;고익배
    • Journal of Pharmaceutical Investigation
    • /
    • 제25권1호
    • /
    • pp.55-62
    • /
    • 1995
  • W/O and O/W emulsions of tegafur (50 mg/5 ml/kg) were orally administered to rats to compare with their mesenteric lymphatic delivery effects. And also in order to demonstrate the lymph targeting associated to the oral route, it was deemed necessary to investigate the fate of solution after oral administration as a control. Lymph and plasma samples were periodically taken from each subject of mesenteric lymphatic duct cannulated rats. Then, lymph and plasma levels of tegafur and its active metabolite, 5-FU, were simultaneously observed. Also pharmacokinetic parameters were compared with each others. On the other hand, most previous studies of lymphatic transport have not addressed the question of whether an increase in mesenteric or thoracic lymph transport by the manipulation of a suspected variable was due to a selective delivery to the intestinal lymphatics or an overall increase availability. Therefore, based on a physiologically based pharmacokinetic model which represents the characteristics of lymphatic systems, we are also going to determine the contributions of mesenteric lymph transport versus thoracic lymph transport of tegafur reported in reference(13). In comparison with tegafur solution, AUC and mean residence time of plasma tegafur were significantly increased in W/O emulsion but significantly decreased in O/W emulsion. Lymph flow rates were similar in both solution and W/O emulsion but half in O/W emulsion. AUC of tegafur in mesenteric lymph and in plasma for W/O emulsion were 3.7 times and 2.9 times more than those for O/W emulsion, respectively. And AUC of 5-FU in thoracic lymph for W/O emulsion was 3.7 times more than that for O/W emulsion. These results suggested that lymphatic delivery or tegafur by W/O emulsion was more effective than that by on emulsion due to its differences or formation ability of chylomicrons.

  • PDF

B와 W의 함량이 무전해 Co 합금 박막의 경도에 미치는 영향 연구 (Effect of B and W Contents on Hardness of Electroless Co Alloy Thin Films)

  • 임태호;김재정
    • Korean Chemical Engineering Research
    • /
    • 제56권6호
    • /
    • pp.895-900
    • /
    • 2018
  • 본 연구에서는 Co-B, Co-W-B 합금 박막 형성을 위한 무전해 전착법을 고안하고, 이를 통해 형성한 합금 박막의 B과 W의 함량이 박막의 경도에 미치는 영향을 살펴보았다. 무전해 전착을 통해 무정형 상태의 Co 합금 박막을 성공적으로 형성할 수 있었으며, 환원제인 dimethylamine borane과 W의 원료인 sodium tungstate dihydrate의 농도를 조절함으로써 Co 합금 박막 내 혼합되는 B과 W의 함량을 조절하였다. 이를 통해 Co 합금 박막 내 전위(dislocation)의 전파(propagation)를 억제하는 B과 W의 함량이 증가할수록 박막의 경도가 증가함을 확인할 수 있었다. 뿐만 아니라, 무전해 전착 시 포기(aeration)를 수행하지 않을 경우에 포기를 수행한 경우보다 Co 합금 박막 내 B과 W의 함량을 대폭 증가시킬 수 있었고 최종적으로 Co-W-B 합금 박막의 경도를 8.9 (${\pm}0.3$) GPa까지 향상시켰다.

비대칭 광도곡선을 갖는 W UMa 형 식쌍성 (ASTMMETRIC LIGHT CURVE OF W UMa TYPE ECLIPSING BINARY SYSTEM)

  • 오규동
    • Journal of Astronomy and Space Sciences
    • /
    • 제11권2호
    • /
    • pp.196-207
    • /
    • 1994
  • 소위 O'Connell효과라고 하는 비대칭 광도곡선을 갖는 27개의 W UMa형 식쌍성들을 수집하고 광도곡선 형태에 다라 12개의 +형과 15개의 -형으로 분류하였다. 이렇게 분류된 별들을 관측된 물리량 사이의 상대적인 상관관계와 진화상태를 조사하였다.

  • PDF

비-동질 안정 프로세스 기반 임베디드 시스템 소프트웨어의 신뢰성 특성에 관한 연구 (A study on the Reliability System Software based on NHPP(Non-Homogeneous Poisson Process)

  • 한상섭;백영구;이근석;전현덕;류호중;이기서
    • 한국철도학회:학술대회논문집
    • /
    • 한국철도학회 2001년도 춘계학술대회 논문집
    • /
    • pp.347-358
    • /
    • 2001
  • In this paper, we apply NHPP model example to s/w process in order to get to know s/w reliability. The test is constructed by a test zig of commercial product loaded real embedded system s/w. It is established to s/w reliability prediction and estimation of real-time embedded system s/w. It is computed the prediction value of cumulative failures, the failure intensity, the reliability and the estimation value of MTTF, Failure Rate. To the more realization of high reliability in the real-time embedded system s/w, if the embedded system s/w is ensured to the test coverage and constructed to stable s/w process & operating system, we can improve the performance and the reliability characteristic of the real-time embedded system s/w.

  • PDF

Crystal Structure of Pentapotassium Disodium Hexatungstoantimonate(V) Dodecahydrate, $K_5Na_2[SbW_6O_{24}]\cdot12H_2O$

  • Lee, Uk;Sasaki, Yukiyoshi
    • Bulletin of the Korean Chemical Society
    • /
    • 제8권1호
    • /
    • pp.1-3
    • /
    • 1987
  • The crystal structure of $K_5Na_2[SbW_6O_{24}]{\cdot}12H_2O$ has been determined. Final R = 0.081 for 890 observed independent reflections collected by diffractometry. Crystal data as follows; trigonal, space group R3m, a = 9.794(1) ${\AA},\;{\alpha}$ = 84.72$(1)^{\circ}$, Z = 1. The heteropolyanion has a structure with point symmetry $D_{3d}$ (3m), of the ideal Anderson-type heteropolyanion. The Sb-W and W-W distances are 3.259(2) and 3.259(3) ${\AA}$. Three types of W-O ($W-O_t,\;W-O_b\;and\;W-O_c$) distances are 1.73(2), 1.95(4) and 2.20(3) ${\AA}$. The Sb-O distance is 1.97(3) ${\AA}$.

ANSYS 프로그램을 이용한 50kW급 풍력터빈에 관한 연구 (A Study of 50kW Wind Turbine by Using ANSYS Program)

  • 이달호;박정철
    • 한국정보전자통신기술학회논문지
    • /
    • 제15권3호
    • /
    • pp.198-204
    • /
    • 2022
  • 본 논문에서는 ANSYS 유동해석 시뮬레이션 프로그램을 이용하여 5kW와 50kW 수직축 풍력터빈에 대해 연구였다. 5kW급 수직축 풍력터빈은 주 블레이드의 갯수와 보조 블레이드의 개수를 각각 30개로 하였고 주속비(TSR)를 0.2에서 06까지 변화를 주면서 전기적 특성을 분석하였다. 5kW급 수직축 풍력터빈의 전기적 특성을 기초로 하여 50kW급 수직축 풍력터빈을 설계 하였다. 5kW급 풍력발전은 주속비가 0.5일 때 9.5kW의 출력과 0.28의 효율이 최대로 나타났다. 출력전류(Ip)와 출력전압(Ep)을 계산한 결과, 주속비가 증가하면 출력전류(Ip)는 감소되고 출력전압(Ep)은 증가되는 것을 알 수가 있었다. 그리고 주속비를 변화주어도 5kW급 풍력발전은 5kW 이상 출력이 측정되었다. 주속비를 0.3부터 0.6까지 변화시켰을 때, 50kW급 풍력발전은 50kW 이상 출력되었다. 50kW급 풍력발전은 주속비가 0.4일 때, 출력은 58.37[kW]이고 효율은 0.318로 최대로 나타났으며, 제안한 50kW 풍력발전이 설계조건을 만족함을 확인하였다.

Proteome characterization reveals the role of pollen and pistil of W22 (ga1; Ga1) in maize

  • Roy, Swapan Kumar;Yu, Jin;Kamal, Abu Hena Mostafa;Kwon, Soo Jeong;Cho, Kun;Cho, Seong-Woo;So, Yoon-Sup;Woo, Sun Hee
    • 한국작물학회:학술대회논문집
    • /
    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
    • /
    • pp.129-129
    • /
    • 2017
  • The first key point to the successful pollination and fertilization in plants is the pollen pistil interaction, referring to the cellular and molecular levels, which mainly play active roles in limiting gene flow among maize populations and between maize and teosinte. This study was carried out to identify proteins and investigate the mechanism of gametophytic factors using protein analysis. W22 (ga1); which didn't carry a gametophytic factor and W22 (Ga1), a near iso-genic line were used for the proteome investigation. SDS-PAGE was executed to investigate proteins in the pollen and pistil of W22 (ga1) and W22 (Ga1). A total of 44 differentially expressed proteins were identified in the pollen and pistil on SDS-PAGE using LTQ-FTICR MS. Among the 44 proteins, a total of 24 proteins were identified in the pollen of W22 (ga1) and W22 (Ga1) whereas 20 differentially expressed proteins were identified from the pistil of W22 (Ga) and W22 (Ga1). However, in pollen, 2 proteins were identified only in the W22 (ga1) and 12 proteins only in the W22 (Ga1) whereas 10 proteins were confirmed from the both of W22 (ga1) and W22 (Ga1). In contrary, 10 proteins were appeared only in the pistil of W22 (ga1) and 7 proteins from W22 (Ga1) while 3 proteins confirmed in the both of W22 (ga1) and W22 (Ga1). Moreover, the identified proteins were generally involved in hydrolase activity, nucleic acid binding and nucleotide binding. These results help to reveal the mechanism of gametophytic factors and provide a valuable clue for the pollen and pistil research in maize. In addition, it might provide a comprehensive insight on the proteins that were involved in the regulation of pollen-pistil interaction.

  • PDF

A Study on the Effects of Salinity and Washing in on Aerobic Composting of Food Wastes

  • Park, Seok-Hwan
    • 한국환경보건학회:학술대회논문집
    • /
    • 한국환경보건학회 2004년도 International Conference Global Environmental Problems and their Health Consequences
    • /
    • pp.207-209
    • /
    • 2004
  • This study was performed to estimate the effects of salinity and washing of food wastes on temperature, pH, and salinity in aerobic composting of food wastes. Weight ratios of food wastes to water in washing were 1:0(Control), 1:1(W-1), 1:2(W-2), 1:3(W-3) and 1:4(W-4), respectively. Ratios of food wastes to wood chips in reactor of Control, W-1, W-2, W-3 and W-4 were 5kg:5L, respectively. Reactors were operated for 24 days with 1 hour stirring by 1 rpm and 2 hours aeration per day. The increase in the ratio of food wastes to water used in washing resulted in the decrease of the highest reaction temperature and the elongation of the high temperature reaction period. The lowering of the ratio of food wastes to water used in washing resulted in faster pH increase The final salinities of Control, W-1, W-2, W-3 and W-4 were 0.95%, 0.73%, 0.65%, 0.57% and 0.41%, respectively.

  • PDF

An Acoustic Study of the Perceptual Significance of F2 Transition of /w/ in English and Korean

  • Kang, Hyun-Sook
    • 음성과학
    • /
    • 제13권4호
    • /
    • pp.7-21
    • /
    • 2006
  • The intent of the present study is to investigate the acoustic properties of Korean /w/ in various phonological contexts, compare them with those of English /w/, and attempt to explain why English /w/'s are perceived differently by Korean speakers depending on the phonological contexts. Experiments 1 and 2 present the acoustic measure of F2 of Korean /w/ in various linguistic positions and show that unlike English /w/, Korean /w/ shows quite a strong coarticulation with the following vowel. Based on these experiments, Experiment 3 investigates why English /w/ is adapted differently into Korean. Specifically, it discusses why English /wain/ is adapted as /wain/ whereas English /twin/ is adapted into Korean as $/t^{h_i}win/$ with an extra vowel. This study argues that the different perception of English /w/ by Korean and English speakers is due to the different F2 transitional pattern of /w/ in Korean and English in various phonological contexts. It also argues that the F2 transitional pattern is an important factor in the perception of /w/.

  • PDF