• Proceedings of the KSMRM Conference
• /
• 1999.11a
• /
• pp.97-97
• /
• 1999

• 대한핵의학회:학술대회논문집
• /
• 1966.11a
• /
• pp.97.3-97.3
• /
• 1966

• Journal of the Korean Chemical Society
• /
• v.67 no.5
• /
• pp.348-352
• /
• 2023

p97, a universally conserved AAA+ ATPase, holds a central position in the ubiquitin-proteasome system, orchestrating myriad cellular activities with significant therapeutic implications. This protein primarily interacts with a diverse set of adaptor proteins through its N-terminal domain (NTD), which is structurally located at the periphery of the D1 hexamer ring. While there have been numerous structural elucidations of p97 complexed with adaptor proteins, the stoichiometry has remained elusive. In this work, we present the crystal structure of the p97-N/D1 hexamer bound to the FAF1-UBX domain at a resolution of 3.1 Å. Our findings reveal a 6:6 stoichiometry between the p97 hexamer and FAF1-UBX domain, deepening our understanding from preceding structural studies related to p97-NTD and UBX domain-containing proteins. These insights lay the groundwork for potential therapeutic interventions addressing cancer and neurodegenerative diseases.

• Proceedings of the Korean Ceranic Society Conference
• /
• 2002.10a
• /
• pp.97.1-97
• /
• 2002

• Journal of the Korea Construction Safety Engineering Association
• /
• s.23
• /
• pp.86-91
• /
• 1997

노동부 ‘97. 산업재해감소 목표재해율 0.74%. 사망만인율 1.99 달성을 위해 산업안전선진화 3개년 계획을 수립하고 사업장의 자율안전관리 정착, 산재취약부문 중점관리 안전문화운동 확산 등에 주력하기로 하였다. 이러한 노동부의 ‘97. 산업안전보건업무 추진 세부계획에 대하여 알아보기로 한다.

• Journal of Microbiology
• /
• v.45 no.4
• /
• pp.344-349
• /
• 2007

We have isolated previously three synthetic lethal mutants in Schizosaccharomyces pombe, which genetically interact with mex67, in order to identify the genes involved in mRNA export. A novel nup97 gene was isolated by complementation of the growth defect in one of the synthetic lethal mutants, SLMex3. The nup97 gene contains one intron and encodes an 851 amino-acid protein that is similar to nucleoporins, Nppl06p in S. pombe and Nic96p in Saccharomyces cerevisiae. The nup97 gene is essential for vegetative growth, and nup97 null mutant harboring pREP41X-Nup97 showed $poly(A)^+$ RNA export defect when expression of nup97 is repressed in the presence of thiamine. These results suggest that nup97 is involved in mRNA export from the nucleus to cytoplasm.

• Journal of the Mineralogical Society of Korea
• /
• v.25 no.2
• /
• pp.105-115
• /
• 2012

The consolidants have been widely used for the consolidation of decaying heritage stone surfaces. In this study, X-ray diffraction analysis, polarized and stereo-microscope and scanning electron microscope were used to study the surface characterization of granite, sandstone and marble, and to assess the efficiency and the effects of the developed condolidants in the field. The developed consolidants used in this experiment are 100%1T1G and 3%40nm/97%1T1G. The effects of consolidants are 3%40nm/97%1T1G${\gg}$100%1T1G in granite, 3%40nm/97%1T1G>100%1T1G in sandstone, and 3%40nm/97% 1T1G=100%1T1G in marble. The characteristics of rock surface when treated with consolidants show different result according to consolidantes type. This result of treating with consolidant can be used for the conservation of an decaying heritage stone.

• KOREAN ASSOCIATION OF OCCUPATIONAL HEALTH NURSES
• /
• v.12 no.3 s.44
• /
• pp.97-97
• /
• 2005

• The Science & Technology
• /
• v.31 no.3 s.346
• /
• pp.97-97
• /
• 1998

• The Journal of the Korean dental association
• /
• v.26 no.2 s.225
• /
• pp.97-97
• /
• 1988